Quelle organisation du conseil pour accompagner l'innovation en agriculture de conservation ? Le cas du Lac Aloatra à Madagascar.

La zone du Lac Aloatra fait face à un accroissement de sa population, une stagnation de la production rizicole et une augmentation des cultures sur des terres exondées peu fertiles. Pour favoriser une agriculture durable des techniques d'agriculture de conservation, et notamment les systèmes de semis sous couverture végétale, sont proposés par des projets. La progression des superficies concernées par ces nouvelles techniques reste modeste et interroge la pertinence des appuis fournis aux paysans, notamment en matière de conseil. L'objectif de cette communication est de définir la nature d'un conseil permettant d'accompagner une innovation systémique et radicale (le développement des SCV) en favorisant les apprentissages et l'accès aux services. Le travail s'appuie sur des enquêtes auprès des paysans et des acteurs du conseil. Les résultats montrent la dominance du conseil technique fourni par un projet dédié à la promotion des SCV, la volonté mais aussi difficulté à promouvoir un conseil qui aborde la complexité de l'exploitation en interaction avec les changements techniques proposés. Les résultats interrogent la méthode de conseil mobilisée pour atteindre les objectifs mais aussi la capacité des conseillers à développer un conseil co-construit. Ils montrent également la prééminence des fournisseurs de conseil et du projet dans les orientations du conseil et la faible capacité des paysans à influer sur les choix qui sont faits. Ils interrogent la durabilité du dispositif de conseil dans un contexte de financement du conseil par l'aide extérieure

Generating and Adding Flows on Locally Complete Metric Spaces

As a generalization of a vector field on a manifold, the notion of an arc field on a locally complete metric space was introduced in \cite{BC}. In that paper, the authors proved an analogue of the Cauchy-Lipschitz Theorem i.e they showed the existence and uniqueness of solution curves for a time independent arc field. In this paper, we extend the result to the time dependent case, namely we show the existence and uniqueness of solution curves for a time dependent arc field. We also introduce the notion of the sum of two time dependent arc fields and show existence and uniqueness of solution curves for this sum.Comment: 29 pages,6 figure

Heavy Viable Trajectories of Controlled Systems

We define and study the concept of heavy viable trajectories of a controlled system with feedbacks. Viable trajectories are trajectories satisfying at each instant given constraints on the state. The controls regulating viable trajectories evolve according a set-valued feedback map. Heavy viable trajectories are the ones which are associated to the controls in the feedback map whose velocity has at each instant the minimal norm. We construct the differential equation governing the evolution of the controls associated to heavy viable trajectories and we prove their existence

Evaluation of hydrological models on small mountainous catchments: impact of the meteorological forcings

Hydrological modelling of small mountainous catchments is particularly challenging because of the high spatio-temporal resolution required for the meteorological forcings. In situ measurements of precipitation are typically scarce in these remote areas, particularly at high elevations. Precipitation reanalyses propose different alternative forcings for the simulation of streamflow using hydrological models. In this paper, we evaluate the performances of two hydrological models representing some of the key processes for small mountainous catchments (&lt; 300 km2), using different meteorological products with a fine spatial and temporal resolution. The evaluation is performed on 55 small catchments of the northern French Alps. While the simulated streamflows are adequately reproduced for most of the configurations, these evaluations emphasize the added value of radar measurements, in particular for the reproduction of flood events. However, these better performances are only obtained because the hydrological models correct the underestimations of accumulated amounts (e.g. annual) from the radar data in high-elevation areas.</p

The opposite of Dante's hell? The transfer of ideas for social housing at international congresses in the 1850s–1860s

With the advent of industrialization, the question of developing adequate housing for the emergent working classes became more pressing than before. Moreover, the problem of unhygienic houses in industrial cities did not stop at the borders of a particular nation-state; sometimes literally as pandemic diseases spread out 'transnationally'. It is not a coincidence that in the nineteenth century the number of international congresses on hygiene and social topics expanded substantially. However, the historiography about social policy in general and social housing in particular, has often focused on individual cases because of the different pace of industrial and urban development and is thus dominated by national perspectives. In this paper, I elaborate on transnational exchange processes and local adaptations and transformations. I focus on the transfer of the housing model of SOMCO in Mulhouse, (a French house building association) during social international congresses. I examine whether cross-national networking enabled and facilitated the implementation of ideas on the local scale. I will elaborate on the transmission and the local adaptation of the Mulhouse-model in Belgium. Convergences, divergences, and different factors that influenced the local transformations (personal choice, political situation, socioeconomic circumstances) will be taken into accoun

Experimental evidences for the use of two macroalgal species, Ascophyllum nodosum and Fucus vesiculosus as biomonitors of N sources

Proyecto ANILE (CTM2009-08396, CTM2010-08804-E) Plan Nacional de I+D+i y Proyecto RADIALES (IEO)Postprint2,263

The Regulation of MS-KIF18A Expression and Cross Talk with Estrogen Receptor

This study provides a novel view on the interactions between the MS-KIF18A, a kinesin protein, and estrogen receptor alpha (ERα) which were studied in vivo and in vitro. Additionally, the regulation of MS-KIF18A expression by estrogen was investigated at the gene and protein levels. An association between recombinant proteins; ERα and MS-KIF18A was demonstrated in vitro in a pull down assay. Such interactions were proven also for endogenous proteins in MBA-15 cells were detected prominently in the cytoplasm and are up-regulated by estrogen. Additionally, an association between these proteins and the transcription factor NF-κB was identified. MS-KIF18A mRNA expression was measured in vivo in relation to age and estrogen level in mice and rats models. A decrease in MS-KIF18A mRNA level was measured in old and in OVX-estrogen depleted rats as compared to young animals. The low MS-KIF18A mRNA expression in OVX rats was restored by estrogen treatment. We studied the regulation of MS-KIF18A transcription by estrogen using the luciferase reporter gene and chromatin immuno-percipitation (ChIP) assays. The luciferase reporter gene assay demonstrated an increase in MS-KIF18A promoter activity in response to 10−8 M estrogen and 10−7M ICI-182,780. Complimentary, the ChIP assay quantified the binding of ERα and pcJun to the MS-KIF18A promoter that was enhanced in cells treated by estrogen and ICI-182,780. In addition, cells treated by estrogen expressed higher levels of MS-KIF18A mRNA and protein and the protein turnover in MBA-15 cells was accelerated. Presented data demonstrated that ERα is a defined cargo of MS-KIF18A and added novel insight on the role of estrogen in regulation of MS-KIF18A expression both in vivo and in vitro

Estradiol Regulates Expression of Estrogen Receptor ERα46 in Human Macrophages

BACKGROUND:Monocytes and macrophages are key innate immune effector cells that produce cytokines and chemokines upon activation. We and others have shown that 17beta-estradiol (E2) has a direct role in the modulation of monocyte and macrophage immune function. However, relatively little is known about the ability of E2 to regulate isoform expression of estrogen receptors (ERs) in these cells. METHODOLOGY/PRINCIPAL FINDINGS:In this study, we quantify expression of ERalpha and ERbeta in human monocytes and macrophages. We also show for the first time that the N-terminal truncated ERalpha variant, ERalpha46, is expressed in both cell types. Promoter utilization studies reveal that transcription of ERalpha in both cell types occurs from upstream promoters E and F. Treatment with E2 induces ERalpha expression in macrophages but has no effect on ERbeta levels in either cell type. During monocyte-to-macrophage differentiation, ERalpha is upregulated in a time-dependent manner. Previous studies by our group demonstrated that E2 treatment attenuates production of the chemokine CXCL8 in an ER-dependent manner. We now show that ERalpha expression levels parallel the ability of E2 to suppress CXCL8 production. CONCLUSIONS/SIGNIFICANCE:This work demonstrates for the first time that human macrophages predominantly express the truncated ER variant ERalphap46, which is estradiol-inducible. This is mediated through usage of the ERalpha F promoter. Alternative promoter usage may account for tissue and cell type-specific differences in estradiol-induced effects on gene expression. These studies signify the importance of ERalpha expression and regulation in the ability of E2 to modulate innate immune responses

Modelling of the effect of ELMs on fuel retention at the bulk W divertor of JET

Effect of ELMs on fuel retention at the bulk W target of JET ITER-Like Wall was studied with multi-scale calculations. Plasma input parameters were taken from ELMy H-mode plasma experiment. The energetic intra-ELM fuel particles get implanted and create near-surface defects up to depths of few tens of nm, which act as the main fuel trapping sites during ELMs. Clustering of implantation-induced vacancies were found to take place. The incoming flux of inter-ELM plasma particles increases the different filling levels of trapped fuel in defects. The temperature increase of the W target during the pulse increases the fuel detrapping rate. The inter-ELM fuel particle flux refills the partially emptied trapping sites and fills new sites. This leads to a competing effect on the retention and release rates of the implanted particles. At high temperatures the main retention appeared in larger vacancy clusters due to increased clustering rate