A Metabolomic Approach to the Study of Wine Micro-Oxygenation

Wine micro-oxygenation is a globally used treatment and its effects were studied here by analysing by untargeted LC-MS the wine metabolomic fingerprint. Eight different procedural variations, marked by the addition of oxygen (four levels) and iron (two levels) were applied to Sangiovese wine, before and after malolactic fermentation

Diagnostic yield of next-generation sequencing in very early-onset inflammatory bowel diseases: a multicenter study (vol 12, pg 1104, 2021)

Transplantation and immunomodulatio

A family of regression methods derived from standard PLSR

The standard PLSR is presented from a geometric point of view consisting of two projections. In the first, the scores are obtained after an oblique projection of the spectra onto the loadings. In the second, the vector of response values is projected orthogonally onto the scores. A metric is introduced for the oblique projection and a new algorithm for the calculation of the loadings into the variables space is proposed. This work also develops a new parameter, a vector, whose different values lead to different regression models with their own abilities of prediction; one of them is the exact form of the standard PLSR. Two applications are described to illustrate the performance of the proposed method called VODKA regression, which is also a way to build least square regressions by introducing additional knowledge into the models

Nano structuration of zirconia under irradiation: A way to enhance the mechanical stability of zirconia layer

Zirconia is one of the most important ceramic materials because of the large range of industrial applications (catalysis, coatings, spacecraft shielding, paint additives, oxygen sensors, fuel cells, nuclear fuel matrix, alternative high permitivity material to replace silicon oxide as gate dielectric in MOS devices...). It is now well established that a monoclinic to tetragonal phase transition occurs in this material. This transition can for instance be trigged by the grain size. The mechanism of this phase transition is now clearly understood. Zirconia can be considered a textbook example for describing these effects. In this paper, we will discuss the mechanism of the tetragonal to monoclinic martensitic phase transition induced by irradiation within the Landau theory framework, pointing out the peculiar effects related to nanostructuration of this material by irradiation. Such a work is an illustrative example of structural modification of solids induced by irradiation