421 research outputs found
Correlated theory of triplet photoinduced absorption in phenylene-vinylene chains
In this paper we present results of large-scale correlated calculations of
triplet photoinduced absorption (PA) spectrum of oligomers of
poly-(para)phenylenevinylene (PPV) containing up to five phenyl rings. In
particular, the high-energy features in the triplet PA spectrum of oligo-PPVs
are the focus of this study, which, so far, have not been investigated
theoretically, or experimentally. The calculations were performed using the
Pariser-Parr-Pople (PPP) model Hamiltonian, and many-body effects were taken
into account by means of multi-reference singles-doubles configuration
interaction procedure (MRSDCI), without neglecting any molecular orbitals. The
computed triplet PA spectrum of oligo-PPVs exhibits rich structure consisting
of alternating peaks of high and low intensities. The predicted higher energy
features of the triplet spectrum can be tested in future experiments.
Additionally, theoretical estimates of exciton binding energy are also
presented.Comment: To appear in Phys. Rev.
Theory of Electric Field-Induced Photoluminescence Quenching in Disordered Molecular Solids
The dynamics of excitons in disordered molecular solids is studied
theoretically, taking into account migration between different sites,
recombination, and dissociation into free charge carriers in the presence of an
electric field. The theory is applied to interpret the results of electric
field-induced photoluminescence (PL) quenching experiments on molecularly doped
polymers by Deussen et al. [Chem. Phys. 207, 147 (1996)]. Using an
intermolecular dissociation mechanism, the dependence of the PL quenching on
the electric field strength and the dopant concentration, and the time
evolution of the transient PL quenching can be well described. The results
constitute additional proof of the distinct exciton dissociation mechanisms in
conjugated polymer blends and molecularly doped polymers.Comment: 4 pages RevTeX, 3 Postscript figure
Harding University Course Catalog 1988-1989
Catalog of Harding University 1988-1989https://scholarworks.harding.edu/catalogs/1050/thumbnail.jp
Beyond mobile phone displays: Flat panel display technology for biomedical applications
Organ-on-Chips (OoCs) have emerged as a human-specific experimental platform for preclinical research and therapeutics testing that will reduce the cost of pre-clinical drug development, provide better physiological relevance and replace animal testing. Yet, the lack of standardization and cost-effective fabrication technologies can hamper wide-spread adoption of OoCs. In this work we validate the use of flat panel display (FPD) technology as an enabling and cost-effective technology platform for biomedical applications by demonstrating facile integration of key OoC modules like microfluidics and micro electrode arrays (MEAs) in the standardized 96-well plate format. Individual and integrated modules were tested for their biological applicability in OoCs. For microelectrode arrays we demonstrate 90–95% confluency, 3 days after cell seeding and >70% of the initial mitochondrial cell activity for microfluidic devices. Thus highlighting the biocompatibility of these modules fabricated using FPD technology. Furthermore, we provide two examples of monolithically integrated microfluidics and microelectronics, i.e. integrated electronic valves and integrated MEAs, that showcase the strength of FPD technology applied to biomedical device fabrication. Finally, the merits and opportunities provided by FPD technology are discussed through examples of advanced structures and functionalities that are unique to this enabling platform
Response to 2009 Pandemic Influenza A (H1N1) Vaccine in HIV-Infected Patients and the Influence of Prior Seasonal Influenza Vaccination
Background: The immunogenicity of 2009 pandemic influenza A(H1N1) (pH1N1) vaccines and the effect of previous influenza vaccination is a matter of current interest and debate. We measured the immune response to pH1N1 vaccine in HIV-infected patients and in healthy controls. In addition we tested whether recent vaccination with seasonal trivalent inactivated vaccine (TIV) induced cross-reactive antibodies to pH1N1. (clinicaltrials.gov Identifier:NCT01066169) Methods and Findings: In this single-center prospective cohort study MF59-adjuvanted pH1N1 vaccine (Focetria®, Novartis) was administered twice to 58 adult HIV-infected patients and 44 healthy controls in November 2009 (day 0 and day 21). Antibody responses were measured at baseline, day 21 and day 56 with hemagglutination-inhibition (HI) assay. The seroprotection rate (defined as HI titers ≥1:40) for HIV-infected patients was 88% after the first and 91% after the second vaccination. These rates were comparable to those in healthy controls. Post-vaccination GMT, a sensitive marker of the immune competence of a group, was lower in HIV-infected patients. We fou
Gender differences in the use of cardiovascular interventions in HIV-positive persons; the D:A:D Study
Peer reviewe
Influenza vaccination for immunocompromised patients: systematic review and meta-analysis from a public health policy perspective.
Immunocompromised patients are vulnerable to severe or complicated influenza infection. Vaccination is widely recommended for this group. This systematic review and meta-analysis assesses influenza vaccination for immunocompromised patients in terms of preventing influenza-like illness and laboratory confirmed influenza, serological response and adverse events
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