1,177 research outputs found
On deconvolution problems: numerical aspects
An optimal algorithm is described for solving the deconvolution problem of
the form given the noisy data ,
The idea of the method consists of the
representation , where is a compact operator, is
injective, is the identity operator, is not boundedly invertible, and
an optimal regularizer is constructed for . The optimal regularizer is
constructed using the results of the paper MR 40#5130.Comment: 7 figure
Generalized Qualification and Qualification Levels for Spectral Regularization Methods
The concept of qualification for spectral regularization methods for inverse
ill-posed problems is strongly associated to the optimal order of convergence
of the regularization error. In this article, the definition of qualification
is extended and three different levels are introduced: weak, strong and
optimal. It is shown that the weak qualification extends the definition
introduced by Mathe and Pereverzev in 2003, mainly in the sense that the
functions associated to orders of convergence and source sets need not be the
same. It is shown that certain methods possessing infinite classical
qualification, e.g. truncated singular value decomposition (TSVD), Landweber's
method and Showalter's method, also have generalized qualification leading to
an optimal order of convergence of the regularization error. Sufficient
conditions for a SRM to have weak qualification are provided and necessary and
sufficient conditions for a given order of convergence to be strong or optimal
qualification are found. Examples of all three qualification levels are
provided and the relationships between them as well as with the classical
concept of qualification and the qualification introduced by Mathe and
Perevezev are shown. In particular, spectral regularization methods having
extended qualification in each one of the three levels and having zero or
infinite classical qualification are presented. Finally several implications of
this theory in the context of orders of convergence, converse results and
maximal source sets for inverse ill-posed problems, are shown.Comment: 20 pages, 1 figur
Solution to the problem of tomographic scanning of objects by small area X-Ray detectors
Standard X-Ray tomographic setups basically consist of 3 parts: radiation source, mechanics for mounting a sample and detector system. Each part of tomographic setup in one way or another contributes into the quality of reconstructed images. Detector system is responsible for data acquisition process. Development of detectors improves them in terms of resolution, acquisition speed, dark current etc. Such improvements increases costs for producing of detectors as well as their final price. Tomographic scanning of long objects requires using detectors of corresponding size. It makes tomographic setups expensive, because the price of detectors also increases with increasing of their size. Presented work proposes to solve this problem by shifting detector along the longest dimension of the sample and applying optimized filtered backprojection algorithm
The route to transcription initiation determines the mode of transcriptional bursting in E. coli
Transcription is fundamentally noisy, leading to significant heterogeneity across bacterial populations. Noise is often attributed to burstiness, but the underlying mechanisms and their dependence on the mode of promotor regulation remain unclear. Here, we measure E. coli single cell mRNA levels for two stress responses that depend on bacterial sigma factors with different mode of transcription initiation (σ70 and σ54). By fitting a stochastic model to the observed mRNA distributions, we show that the transition from low to high expression of the σ70-controlled stress response is regulated via the burst size, while that of the σ54-controlled stress response is regulated via the burst frequency. Therefore, transcription initiation involving σ54 differs from other bacterial systems, and yields bursting kinetics characteristic of eukaryotic systems
Global Saturation of Regularization Methods for Inverse Ill-Posed Problems
In this article the concept of saturation of an arbitrary regularization
method is formalized based upon the original idea of saturation for spectral
regularization methods introduced by A. Neubauer in 1994. Necessary and
sufficient conditions for a regularization method to have global saturation are
provided. It is shown that for a method to have global saturation the total
error must be optimal in two senses, namely as optimal order of convergence
over a certain set which at the same time, must be optimal (in a very precise
sense) with respect to the error. Finally, two converse results are proved and
the theory is applied to find sufficient conditions which ensure the existence
of global saturation for spectral methods with classical qualification of
finite positive order and for methods with maximal qualification. Finally,
several examples of regularization methods possessing global saturation are
shown.Comment: 29 page
Force traction microscopy: An inverse problem with pointwise observations
Force Traction Microscopy is an inversion method that allows to obtain the stress field applied by a living cell on the environment on the basis of a pointwise knowledge of the displacement produced by the cell itself. This classical biophysical problem, usually addressed in terms of Green functions, can be alternatively tackled using a variational framework and then a finite elements discretization. In such a case, a variation of the error functional under suitable regularization is operated in view of its minimization. This setting naturally suggests the introduction of a new equation, based on the adjoint operator of the elasticity problem. In this paper we illustrate the rigorous theory of the two-dimensional and three dimensional problem, involving in the former case a distributed control and in the latter case a surface control. The pointwise observations require to exploit the theory of elasticity extended to forcing terms that are Borel measure
Adaptive Covariance Estimation with model selection
We provide in this paper a fully adaptive penalized procedure to select a
covariance among a collection of models observing i.i.d replications of the
process at fixed observation points. For this we generalize previous results of
Bigot and al. and propose to use a data driven penalty to obtain an oracle
inequality for the estimator. We prove that this method is an extension to the
matricial regression model of the work by Baraud
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