26 research outputs found

    Field Validation of Generic Type 4 Wind Turbine Models Based on IEC and WECC Guidelines

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    The generic wind turbine models developed in recent years by the International Electrotechnical Commission (IEC) and the Western Electricity Coordinated Council (WECC) are intended to meet the needs of public, standard, and relatively simple (small number of parameters and computational requirements) wind turbine and wind farm models used to conduct transient stability analysis. Moreover, the full-scale converter (FSC) wind turbine technology referred to as Type 4 by IEC and WECC, is increasingly used in current power systems due to its control benefits. Hence, the development of this generic model has become a priority.This study presents the validation of two generic Type 4 wind turbine models, which have been developed in accordance with the IEC and WECC guidelines, respectively. Field data collected from a real wind turbine located in a Spanish wind farm was used to validate both generic Type 4 wind turbine models following the IEC validation guidelines. Ten different test cases are considered, varying not only the depth and duration of the faults but also the load of the wind turbine. The parameters of the models were kept constant for all the simulation cases, aiming to evaluate the accuracy of the models when facing different voltage dips

    Hyperlipidemia-associated renal damage decreases Klotho expression in kidneys from ApoE knockout mice

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    Background: Klotho is a renal protein with anti-aging properties that is downregulated in conditions related to kidney injury. Hyperlipidemia accelerates the progression of renal damage, but the mechanisms of the deleterious effects of hyperlipidemia remain unclear. Methods: We evaluated whether hyperlipidemia modulates Klotho expression in kidneys from C57BL/6 and hyperlipidemic apolipoprotein E knockout (ApoE KO) mice fed with a normal chow diet (ND) or a Western-type high cholesterol-fat diet (HC) for 5 to 10 weeks, respectively. Results: In ApoE KO mice, the HC diet increased serum and renal cholesterol levels, kidney injury severity, kidney macrophage infiltration and inflammatory chemokine expression. A significant reduction in Klotho mRNA and protein expression was observed in kidneys from hypercholesteromic ApoE KO mice fed a HC diet as compared with controls, both at 5 and 10 weeks. In order to study the mechanism involved in Klotho down-regulation, murine tubular epithelial cells were treated with ox-LDL. Oxidized-LDL were effectively uptaken by tubular cells and decreased both Klotho mRNA and protein expression in a time- and dose-dependent manner in these cells. Finally, NF-κB and ERK inhibitors prevented ox-LDL-induced Klotho downregulation. Conclusion: Our results suggest that hyperlipidemia-associated kidney injury decreases renal expression of Klotho. Therefore, Klotho could be a key element explaining the relationship between hyperlipidemia and aging with renal disease.This work has been supported by grants from FIS (Programa Miguel Servet: CP10/00479) to JAM and ISCIII (Programa de Estabilizacio´n) and PI10/00234 to LMBC. Fundacio´n Conchita Ra´bago to CS and ARN. Ministry of Science (SAF2012/38830) and Sociedad Espan˜ola de Nefrologia to CGG. ISCIII and FEDER funds PS09/00447, Sociedad Espan˜ola de Nefrologia, ISCIII-RETIC REDinREN/RD06/0016, Comunidad de Madrid/CIFRA/S2010/BMD-2378 to AO, and ISCIII-Redes RECAVA (RD06/0014/0035) REDINREN (RD12/0021/), European Network (HEALTH F2-2008-200647), Euro Salud EUS2005-03565, cvREMOD, Fundacion Lilly, FRIAT and ISCIII fund PI10/00072 to JE. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

    Electrolytic Cell Applied for the Breakdown of Endocrine Disrupting Drugs in Aqueous Tributaries

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    In this chapter, we report previous results about advances of an electrolysis process developed for breakdown of endocrine disrupting drugs in aqueous media. The objective is to achieve the breakdown of two drugs: trimethoprim and a mixture of clavulanic acid-amoxicillin (1:7) with an electrolytic cell by means of oxidization-reduction reactions. The evaluation of the process was carried out using spectrometry techniques UV-Vis, thin layer chromatography (TLC), chemical oxygen demand (COD), and total organic carbon (TOC). Handcrafted mineral carbon electrodes doped with titanium dioxide were designed, platinum and copper wires were placed, and a potassium hydroxide solution was used as electrolyte. The electrolyte, being an alkaline salt, allows the transport of charges from one side to the other, and electrode doped with titanium dioxide is used in order to help the electronic transfer, and the mineral carbon, having a strong affinity for organic and non-polar compounds, performs an adsorption process. Results from several performed assays showed that after 1 hour of treatment, it can be seen the breakdown of the drugs present in a synthetic wastewater solution

    Evaluation of P22 ELISA for the Detection of Mycobacterium bovis-Specific Antibody in the Oral Fluid of Goats

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    The ante-mortem diagnosis of tuberculosis (TB) in ruminants is based mainly on the intradermal tuberculin test and the IFN-γ assay. Antibody (Ab)-based tests have emerged as potential tools for the detection of TB infected animals using serum, plasma, or even milk samples. Oral fluids have also been evaluated as alternative samples with which to detect specific Abs against Mycobacterium bovis in pigs or wild boars, but not in ruminants. The objective of this study was, therefore, to evaluate the performance of an in house-ELISA for TB diagnosis (P22 ELISA) in goats as an experimental model for the diagnosis of TB using oral fluid samples. Oral fluid samples from 64 goats from a TB-infected herd (n = 197) and all the animals from a TB-free herd (n = 113) were analyzed using the P22 ELISA. The estimated sensitivity (Se) and specificity (Sp) were 34.4% (95% CI: 22.4-45.6) and 100% (95% CI: 97.4-100), respectively. The optimal cut-off point was set at 100% according to the ROC analysis. Those animals with a higher level of Abs in their oral fluid attained a higher lesion score (p = 0.018). In fact, when taking into account only the setting of the animals with severe lesions (n = 16), the ELISA showed a Se of 75% (95% CI: 53.7-96.2). Results of the present study suggest that the P22 ELISA is highly specific but has a limited value detecting infected animals in oral fluid samples. Nevertheless, its performance is significantly higher in the presence of severe lesions.This study was funded by the Herramientas para alcanzar la erradicación de la tuberculosis caprina (GoaTBfree) project (PID2019-105155RB-C31) and the Spanish Government's Ministerio de Agricultura, Pesca y Alimentación. JO was supported by an FPU (Formación de Profesorado Universitario) contract-fellowship provided by the Spanish Ministerio de Ciencia, Innovación y Universidades (FPU18/05197).S

    La universidad emocional. La investigación en aprendizaje a través de las emociones. Especial referencia al ámbito universitario

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    Desde hace más de dos décadas, la Inteligencia Emocional (IE) se ha convertido en un concepto de gran interés. Una de las líneas de investigación que más interés ha suscitado en los últimos años, es el papel que tienen las emociones en el aprendizaje de los alumnos, y la influencia que tiene el constructo inteligencia emocional para determinar el rendimiento académico de los estudiantes. Debido a diferencias en la definición del constructo y a distintas metodologías empleadas, los hallazgos no han sido concluyentes. El artículo propone la continuidad en la investigación en IE y, en concreto, abrir más la investigación de la IE en el ámbito universitario (en particular en el área de Administración de Empresa y Finanzas y Contabilidad), trazar el mapa de la Universidad Emocional (alumno y profesor) ya que puede ayudar a interpretar mejor el concepto de éxito académico: buen docente, investigador y gestor; rendimiento, motivación, estilos de aprendizaje, aprensión comunicativa, competencias socio-emocionales, etc. El objetivo del trabajo es presentar la situación actual de la investigación en IE, en concreto en el ámbito universitario, en los distintos tópicos de trabajo y futuras líneas de investigación

    Differences in skin test reactions to official and defined antigens in guinea pigs exposed to non-tuberculous and tuberculous bacteria

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    The single and comparative intradermal tuberculin tests (SITT and CITT) are official in vivo tests for bovine tuberculosis (TB) diagnosis using bovine and avian purified protein derivatives (PPD-B and PPD-A). Infection with bacteria other than Mycobacterium tuberculosis complex (MTC) can result in nonspecific reactions to these tests. We evaluated the performance of the skin test with PPDs and new defined antigens in the guinea pig model. A standard dose (SD) of Rhodococcus equi, Nocardia sp., M. nonchromogenicum, M. monacense, M. intracellulare, M. avium subsp. paratuberculosis, M. avium subsp. avium, M. avium subsp. hominissuis, M. scrofulaceum, M. persicum, M. microti, M. caprae and M. bovis, and a higher dose (HD) of M. nonchromogenicum, M. monacense, M. intracellulare, M. avium subsp. paratuberculosis were tested using PPD-B, PPD-A, P22, ESAT-6-CFP-10-Rv3615c peptide cocktail long (PCL) and fusion protein (FP). The SD of R. equi, Nocardia sp., M. nonchromogenicum, M. monacense, M. intracellulare and M. avium subsp. paratuberculosis did not cause any reactions. The HD of M. nonchromogenicum, M. monacense, M. intracellulare, and M. avium subsp. paratuberculosis and the SD of M. avium subsp. hominissuis, M. scrofulaceum and M. persicum, caused nonspecific reactions (SIT). A CITT interpretation would have considered M. avium complex and M. scrofulaceum groups negative, but not all individuals from M. nonchromogenicum HD, M. monacense HD and M. persicum SD groups. Only animals exposed to M. bovis and M. caprae reacted to PCL and FP. These results support the advantage of complementing or replacing PPD-B to improve specificity without losing sensitivity.info:eu-repo/semantics/publishedVersio

    Effects of a hybrid teaching model (SEM + TGfU) and the model of personal and social responsibility on sportsmanship and enjoyment in 4° Secondary and 1° Baccalaureate students

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    The application of pedagogical models can have positive effects on sportsmanship and students’ enjoyment of Physical Education (PE) lessons. The aim of this study was to compare the influence on sportsmanship and fun of the application of, on the one hand, the combination of the Sports Education Model (SEM) and the Teaching Games for Understanding (TGfU) model and, on the other, the Personal and Social Responsibility Model (PSRM). The participants in this study were a total of 85 Spanish teenagers, 39 girls and 46 boys, studying Secondary Education. They completed the SSI questionnaires adapted to Physical Education (SSI-PE) to analyse their enjoyment, and the Multidimensional Sportsmanship Orientations Scale (MSOS) to analyse sportsmanship. Results showed significant differences in enjoyment when applying both the hybrid model (SEM+TGfU) and the PSRM model (p < .01). It is concluded that both interventions with the hybrid model and the PSRM generate positive effects on students’ enjoyment.La aplicación de modelos pedagógicos puede tener efectos positivos sobre la deportividad y la diversión del alumnado en la clases de Educación Física (EF). El objeto de estudio se basó en comparar la influencia de la aplicación de una hibridación del Modelo de Educación Deportiva (MED) y el Modelo Comprensivo (TGfU), y del Modelo de Responsabilidad Personal y Social (MRPS), sobre la deportividad y la diversión. Para ello, participaron un total de 85 estudiantes, 39 chicas (46%) y 46 chicos (54%), de edades comprendidas entre los 16 y 17 años (16.42 ± 0.50). Los participantes de dos grupos de 4º ESO y dos de 1º BACH, cumplimentaron dos cuestionarios al inicio y al final de la unidad formativa. La versión final española del cuestionario SSI adaptado a la EF (SSI-EF) para analizar la diversión, y la versión española de la Escala Multidimensional de Orientaciones a la Deportividad Multidimensional (MSOS) para analizar la deportividad. Los resultados mostraron diferencias significativas en la diversión percibida al aplicar tanto el modelo híbrido como el MRPS (p < .01). Se concluye afirmando que tanto la intervención a través de un modelo híbrido (MED + TGfU) y mediante el MRPS, genera efectos positivos sobre la diversión del alumnado

    Implementation of IEC 61400-27-1 Type 3 Model: Performance Analysis under Different Modeling Approaches

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    Forecasts for 2023 position wind energy as the third-largest renewable energy source in the world. This rapid growth brings with it the need to conduct transient stability studies to plan network operation activities and analyze the integration of wind power into the grid, where generic wind turbine models have emerged as the optimal solution. In this study, the generic Type 3 wind turbine model developed by Standard IEC 61400-27-1 was submitted to two voltage dips and implemented in two simulation tools: MATLAB/Simulink and DIgSILENT-PowerFactory. Since the Standard states that the responses of the models are independent of the software used, the active and reactive power results of both responses were compared following the IEC validation guidelines, finding, nevertheless, slight differences dependent on the specific features of each simulation software. The behavior of the generic models was assessed, and their responses were also compared with field measurements of an actual wind turbine in operation. Validation errors calculated were comprehensively analyzed, and the differences in the implementation processes of both software tools are highlighted. The outcomes obtained help to further establish the limitations of the generic wind turbine models, thus achieving a more widespread use of Standard IEC 61400-27-1

    Generic Type 3 Wind Turbine Model Based on IEC 61400-27-1: Parameter Analysis and Transient Response under Voltage Dips

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    This paper analyzes the response under voltage dips of a Type 3 wind turbine topology based on IEC 61400-27-1. The evolution of both active power and rotational speed is discussed in detail when some of the most relevant control parameters, included in the mechanical, active power and pitch control models, are modified. Extensive results are also included to explore the influence of these parameters on the model dynamic response. This work thus provides an extensive analysis of the generic Type 3 wind turbine model and provides an estimation of parameters not previously discussed in the specific literature. Indeed, the International Standard IEC 61400-27-1, recently published in February 2015, defines these generic dynamic simulation models for wind turbines, but does not provide values for the parameters to simulate the response of these models. Thus, there is a pressing need to establish correlations between IEC generic models and specific wind turbine manufacturer models to estimate suitable parameters for simulation purposes. Extensive results and simulations are also included in the paper
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