El mercado en el segmento de las parejas sin hijos en Villavicencio (Colombia)

This article discusses how consists demand and supply of goods and services to meet the needs of couples formed by double income no kids called Dink segment. Also review some studies in Colombia and Mexico, to do qualitative methodology was implemented by interviewing 30 couples of different ages and socioeconomic levels. Similarly informa- tion and response with hotels, restaurants and construction, compared to the emergen- ce of these segments are met. The study was conducted in Villavicencio with the aim of characterizing the behavior of consumption of the Dink couples, so that local companies can identify business opportunities designed to meet the needs and expectations of that segment.Este artículo expone la forma como está constituida la demanda y la oferta de bienes y servicios destinados a satisfacer las necesi- dades del segmento conformado por parejas con doble ingreso sin hijos conocidas como Dink. También reseña algunos estudios rea- lizados en Colombia y en México, para ello, se implementó la metodología cualitativa, entrevistando a 30 parejas de diferentes edades y niveles socioeconómicos. De igual forma, se conoció la información y respuesta que tienen los hoteles, restaurantes y las constructoras, frente al surgimiento de es- tos segmentos. El estudio fue realizado en Villavicencio con el objetivo de caracterizar los comportamientos de consumo de las parejas Dink, de tal manera que las empresas locales puedan identificar oportunidades de negocios tendientes a satisfacer las nece- sidades, y expectativas de dicho segmento.Cet article expose la forme dans laquelle est constituée la demande et l’offre de biens et de services destinés à satisfaire les nécessi-tés du segment conformé par des paires avecune double recette sans des enfants connues comme Dink. Il rédige le signalement aussi de quelques études réalisées en Colombie et en Mexique, pour cela la méthodologie qualitative a été mise en application, ayant une entrevue à 30 paires de différents âges et de niveaux socio-économiques. Soyez égal une forme a connu l’information et la réponse qu’ont les hôtels, les restaurants et les constructrices, en face du surgissement de ces segments. L’étude a été réalisée dans Villavicencio avec l’objectif de caractériser les comportements de consommation des paires Dink, tellement que les entreprises locales peuvent identifier les opportunités d’affaires tendantes de satisfaire les néces-sités, et des attentes du dit segment

Tratamiento de la consolidación viciosa del extremo distal del radio

Las fracturas del extremo distal del radio a menudo cursan con un grupo de complicaciones importantes, dentro de estas, la consolidación viciosa constituye una de las más incapacitantes. Su manejo mediante las técnicas de rescate constituye un elemento fundamental para su resolución. Se presenta el caso de una paciente de 60 años de edad, procedencia urbana y antecedentes de salud, atendida en el Hospital General Universitario Dr. Gustavo Aldereguía Lima de Cienfuegos, aquejada de una consolidación viciosa del extremo distal del radio de la mano izquierda como consecuencia de una fractura de Colles anterior. Refirió dolor intenso que le impedía conciliar el sueño y marcada limitación para realizar las actividades de la vida diaria. Se realizó cirugía de rescate consistente en la osteotomía del extremo distal del radio de base dorsal con aporte de injerto según lo propuesto en la técnica de Fernández, con resultados satisfactorios

Tratamiento de la fractura-luxación expuesta del tobillo. Presentación de un caso

La fractura luxación expuesta del tobillo constituye una afección poco frecuente. Se presenta el caso de un paciente masculino, de 57 años de edad, con antecedentes de salud, que acudió a cuerpo de guardia del Hospital General Universitario Dr. Gustavo Aldereguía Lima, de Cienfuegos, tras sufrir un accidente laboral. Para dar solución a esta grave lesión se realizó, de manera urgente, la limpieza quirúrgica de la articulación con soluciones antisépticas, se redujo la fractura luxación y se realizó la osteosíntesis de esta. A las 12 semanas de la cirugía el paciente se reincorporó a sus actividades laborales previas

Evaluación de la seguridad y efecto terapéutico del Itolizumab en pacientes de Camagüey con psoriasis severa

Fundamento: la psoriasis es una enfermedad inflamatoria crónica de la piel que afecta la calidad de vida de los pacientes que la padecen.Objetivo: evaluar la seguridad y efecto terapéutico del anticuerpo monoclonal Itolizumab en pacientes con psoriasis severa, atendidos en el hospital universitario Manuel Ascunce Domenech, de Camagüey, durante el período comprendido entre septiembre de 2012 y diciembre de 2013.Métodos: se realizó un ensayo clínico, fase II, abierto, no controlado, no aleatorizado, del tipo Programa de Uso Clínico Expandido (PUCE), como parte del ensayo “Evaluación de la seguridad y el efecto terapéutico del anticuerpo monoclonal itolizumab (T1h) para el tratamiento de pacientes con Psoriasis severa”, en pacientes con este diagnóstico atendidos en la referida institución y período de tiempo. La muestra de estudio estuvo constituida por 10 pacientes. Los datos fueron extraídos de las historias clínicas y la variable principal de efecto fue el índice clínico definido por el PASI (índice de área y severidad de la psoriasis). El PASI fue evaluado en diferentes momentos mediante un calculador gráfico (PASI-3D). Resultados: la variante clínica en placas predominó en los pacientes estudiados. La respuesta clínica de blanqueamiento se alcanzó en más de las dos terceras partes de los pacientes al final de la fase de mantenimiento, que se mantuvo en el período de observación, con escasos eventos adversos. Conclusiones: se evidenció que el Itolizumab es un medicamento seguro y efectivo en el tratamiento de la psoriasis severa.</p

Dairy product consumption and changes in cognitive performance: two-year analysis of the PREDIMED-Plus Cohort

Scope: Dairy consumption has been suggested to impact cognition; however, evidence is limited and inconsistent. This study aims to longitudinally assess the association between dairy consumption with cognitive changes in an older Spanish population at high cardiovascular disease risk. Methods and results: Four thousand six hundred sixty eight participants aged 55–75 years, completed a validated food frequency questionnaire at baseline and a neuropsychological battery of tests at baseline and 2-year follow-up. Multivariable linear regression models are used, scaled by 100 (i.e., the units of β correspond to 1 SD/100), to assess associations between baseline tertile daily consumption and 2-year changes in cognitive performance. Participants in the highest tertile of total milk and whole-fat milk consumption have a greater decline in global cognitive function (β: –4.71, 95% CI: –8.74 to –0.69, p-trend = 0.020 and β: –6.64, 95% CI: –10.81 to –2.47, p-trend = 0.002, respectively) compared to those in the lowest tertile. No associations are observed between low fat milk, yogurt, cheese or fermented dairy consumption, and changes in cognitive performance. Conclusion:Results suggest there are no clear prospective associations between consumption of most commonly consumed dairy products and cognition, although there may be an association with a greater rate of cognitive decline over a 2-year period in older adults at high cardiovascular disease risk for whole-fat milk

Water intake, hydration status and 2-year changes in cognitive performance: a prospective cohort study

BackgroundWater intake and hydration status have been suggested to impact cognition; however, longitudinal evidence is limited and often inconsistent. This study aimed to longitudinally assess the association between hydration status and water intake based on current recommendations, with changes in cognition in an older Spanish population at high cardiovascular disease risk.MethodsA prospective analysis was conducted of a cohort of 1957 adults (aged 55-75) with overweight/obesity (BMI between >= 27 and = 300 mmol/L (dehydrated). Water intake was assessed as total drinking water intake and total water intake from food and beverages and according to EFSA recommendations. Global cognitive function was determined as a composite z-score summarizing individual participant results from all neuropsychological tests. Multivariable linear regression models were fitted to assess the associations between baseline hydration status and fluid intake, continuously and categorically, with 2-year changes in cognitive performance.ResultsThe mean baseline daily total water intake was 2871 +/- 676 mL/day (2889 +/- 677 mL/day in men; 2854 +/- 674 mL/day in women), and 80.2% of participants met the ESFA reference values for an adequate intake. Serum osmolarity (mean 298 +/- 24 mmol/L, range 263 to 347 mmol/L) indicated that 56% of participants were physiologically dehydrated. Lower physiological hydration status (i.e., greater serum osmolarity) was associated with a greater decline in global cognitive function z-score over a 2-year period (beta: - 0.010; 95% CI - 0.017 to - 0.004, p-value = 0.002). No significant associations were observed between water intake from beverages and/or foods with 2-year changes in global cognitive function.ConclusionsReduced physiological hydration status was associated with greater reductions in global cognitive function over a 2-year period in older adults with metabolic syndrome and overweight or obesity. Future research assessing the impact of hydration on cognitive performance over a longer duration is needed

Effect of a nutritional intervention based on an energy-reduced Mediterranean diet on environmental impact

[EN]To estimate the environmental impact of a dietary intervention based on an energy-reduced Mediterranean diet (MedDiet) after one year of follow-up. Methods Baseline and 1-year follow-up data were used for 5800 participants aged 55–75 years with metabolic syndrome in the PREDIMED-Plus study. Food intake was estimated through a validated semiquantitative food consumption frequency questionnaire, and adherence to the MedDiet was estimated through the Diet Score. Using the EAT-Lancet Commission tables we assessed the influence of dietary intake on environmental impact (through five indicators: greenhouse gas emissions (GHG), land use, energy used, acidification and potential eutrophication). Using multivariable linear regression models, the association between the intervention and changes in each of the environmental factors was assessed. Mediation analyses were carried out to estimate to what extent changes in each of 2 components of the intervention, namely adherence to the MedDiet and caloric reduction, were responsible for the observed reductions in environmental impact. Results We observed a significant reduction in the intervention group compared to the control group in acidification levels (−13.3 vs. -9.9 g SO2-eq), eutrophication (−5.4 vs. -4.0 g PO4-eq) and land use (−2.7 vs. -1.8 m2). Adherence to the MedDiet partially mediated the association between intervention and reduction of acidification by 15 %, eutrophication by 10 % and land use by 10 %. Caloric reduction partially mediated the association with the same factors by 55 %, 51 % and 38 % respectively. In addition, adherence to the MedDiet fully mediated the association between intervention and reduction in GHG emissions by 56 % and energy use by 53 %.SIPublicación en abierto financiada por el Consorcio de Bibliotecas Universitarias de Castilla y León (BUCLE), con cargo al Programa Operativo 2014ES16RFOP009 FEDER 2014-2020 DE CASTILLA Y LEÓN, Actuación:20007-CL - Apoyo Consorcio BUCL

Impact of COVID-19 pandemic on the PREDIMED-Plus randomized clinical trial: Effects on the interventions, participants follow-up, and adiposity

Background: The COVID-19 pandemic has affected the implementation of most ongoing clinical trials worldwide including the PREDIMED-Plus study. The PREDIMED-Plus is an ongoing, multicenter, controlled intervention trial, aimed at weight-loss and cardiovascular disease prevention, in which participants were randomized (1:1 ratio) to an intervention group (energy-reduced Mediterranean diet, promotion of physical activity, and behavioral support) or to a control group (Mediterranean diet with usual care advice). When the pandemic began, the trial was in the midst of the planned intervention. The objective of this report was to examine the effects of the pandemic on the delivery of the intervention and to describe the strategies established to mitigate the possible adverse effects of the pandemic lockdown on data collection and adiposity. Methods: We assessed the integrity of the PREDIMED-Plus trial during 5 identified periods of the COVID-19 pandemic determined according to restrictions dictated by the Spanish government authorities. A standardized questionnaire was delivered to each of the 23 PREDIMED-Plus recruiting centers to collected data regarding the trial integrity. The effect of the restrictions on intervention components (diet, physical activity) was evaluated with data obtained in the three identified lockdown phases: pre lockdown, lockdown proper, and post lockdown. Results: During the lockdown (March/2020-June/2021), 4,612 participants (48% women, mean age 65y) attended pre-specified yearly follow-up visits to receive lifestyle recommendations and obtain adiposity measures. The overall mean (SD) of the proportions reported by each center showed that 40.4% (25.4) participants had in-person visits, 39.8% (18.2) participants were contacted by telephone and 35% (26.3) by electronic means. Participants' follow-up and data collection rates increased across lockdown periods (from ≈10% at onset to ≈80% at the end). Compared to pre-lockdown, waist circumference increased during (0.75 cm [95% CI: 0.60-0.91]) and after (0.72 cm [95% CI: 0.56-0.89]) lockdown. Body weight did not change during lockdown (0.01 kg [95% CI: -0.10 to 0.13) and decreased after lockdown (-0.17 kg [95% CI: -0.30 to -0.04]). Conclusion: Mitigating strategies to enforce the intervention and patient's follow-up during lockdown have been successful in preserving the integrity of the trial and ensuring its continuation, with minor effects on adiposity. Clinical trial registration: https://doi.org/10.1186/ISRCTN89898870, identifier ISRCTN89898870. Keywords: COVID-19; Mediterraean diet; PREDIMED-Plus; clinical trial; lockdown; weight-loss. Copyright © 2023 Paz-Graniel, Fitó, Ros, Buil-Cosiales, Corella, Babio, Martínez, Alonso-Gómez, Wärnberg, Vioque, Romaguera, López-Miranda, Estruch, Tinahones, Lapetra, Serra-Majem, Bueno-Cavanillas, Tur, Martín-Sánchez, Pintó, Gaforio, Matía-Martín, Vidal, Vázquez, Daimiel, García-Gavilán, Toledo, Nishi, Sorlí, Castañer, García-Ríos, García de la Hera, Barón-López, Ruiz-Canela, Morey, Casas, Garrido-Garrido, Tojal-Sierra, Fernández-García, Vázquez-Ruiz, Fernández-Carrión, Goday, Peña-Orihuela, Compañ-Gabucio, Schröder, Martínez-Gonzalez and Salas-Salvadó. Conflict of interest statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

How Did the COVID-19 Lockdown Pandemic Affect the Depression Symptomatology in Mediterranean Older Adults with Metabolic Syndrome?

Background and Aims. To control the COVID-19 spread, in March 2020, a forced home lockdown was established in Spain. In the present study, we aimed to assess the effect of mobility and social COVID-19-established restrictions on depressive symptomatology in older adults with metabolic syndrome. We hypothesize that severe restrictions might have resulted in detrimental changes in depressive symptomatology. Methods. 2,312 PREDIMED-Plus study participants (men = 53:9%; mean age = 64:9±4:8 years) who completed a COVID-19 lockdown questionnaire to assess the severity of restrictions/lockdown and the validated Spanish version of the Beck Depression Inventory-II (BDI-II) during the three established phases concerning the COVID-19 lockdown in Spain (prelockdown, lockdown, and postlockdown) were included in this longitudinal analysis. Participants were categorized according to high or low lockdown severity. Analyses of covariance were performed to assess changes in depressive symptomatology across lockdown phases. Results. No significant differences in participant depression symptomatology changes were observed between lockdown severity categories (low/high) at the studied phases. During the lockdown phase, participants showed a decrease in BDI-II score compared to the prelockdown phase (mean (95% CI), -0.48 (-0.24, -0.72), P < 0:001); a nonsignificantly larger decrease was observed in participants allocated in the low-lockdown category (low: -0.59 (-0.95, -0.23), high: -0.43 (-0.67, -0.19)). Similar decreases in depression symptomatology were found for the physical environment dimension. The post- and prelockdown phase BDI-II scores were roughly similar. Conclusions. The COVID-19 pandemic lockdown was associated with a decrease in depressive symptomatology that returned to prelockdown levels after the lockdown. The degree of lockdown was not associated with depressive symptomatology. The potential preventive role of the physical environment and social interactions on mental disorders during forced home lockdown should be further studie

Environmental education through research as a pedagogical strategy

La educación ambiental es una herramienta teóricopráctica que permite la integración de elementos sociales propios del contexto escolar, creando una ciudadanía consciente. El estudio busco, promover la educación ambiental mediante la investigación como estrategia pedagógica, guiado bajo los lineamientos metodológicos de la IEP con un diseño basado en las trayectorias de indagación, se contó con ochenta (80) participantes de la institución educativa Tucurinca ubicada en el Municipio de Zona Bananera Magdalena. Los resultados dejaron en evidencia diferentes problemáticas ambientales observadas por los estudiantes en la comunidad mediante el proceso de indagación, donde se encontró deterioro del humedal, proliferación de insectos y hongos producidos por basuras en descomposición que afectan a la salud de la población, para esto los estudiantes se organizaron en grupos de investigación y diseñaron propuestas para dar solución a los diferentes problemas encontrados, finalmente estas propuestas fueron divulgadas y socializadas en la feria institucional de la ciencia.Environmental education is a theoretical-practical tool that allows the integration of social elements typical of the school context, creating a conscious citizenship. The study sought to promote environmental education through research as a pedagogical strategy, guided by the methodological guidelines of the IEP with a design based on the trajectories of inquiry, was attended by eighty (80) participants from the educational institution Tucurinca located in the Municipality of Magdalena Bananera Zone. The results showed different environmental problems observed by the students in the community through the process of investigation, where the wetland deterioration was found, as well as the proliferation of insects and fungi produced by decomposing garbage that affect the health of the population. students were organized in research groups and designed proposals to solve the different problems found, finally these proposals were disseminated and socialized in the institutional science fair