From Algorithmic Computing to Autonomic Computing

In algorithmic computing, the program follows a predefined set of rules – the algorithm. The analyst/designer of the program analyzes the intended tasks of the program, defines the rules for its expected behaviour and programs the implementation. The creators of algorithmic software must therefore foresee, identify and implement all possible cases for its behaviour in the future application! However, what if the problem is not fully defined? Or the environment is uncertain? What if situations are too complex to be predicted? Or the environment is changing dynamically? In many such cases algorithmic computing fails. In such situations, the software needs an additional degree of freedom: Autonomy! Autonomy allows software to adapt to partially defined problems, to uncertain or dynamically changing environments and to situations that are too complex to be predicted. As more and more applications – such as autonomous cars and planes, adaptive power grid management, survivable networks, and many more – fall into this category, a gradual switch from algorithmic computing to autonomic computing takes place. Autonomic computing has become an important software engineering discipline with a rich literature, an active research community, and a growing number of applications.:Introduction 5 1 A Process Data Based Autonomic Optimization of Energy Efficiency in Manufacturing Processes, Daniel Höschele 9 2 Eine autonome Optimierung der Stabilität von Produktionsprozessen auf Basis von Prozessdaten, Richard Horn 25 3 Assuring Safety in Autonomous Systems, Christian Rose 41 4 MAPE-K in der Praxis - Grundlage für eine mögliche automatische Ressourcenzuweisung, in der Cloud Michael Schneider 5

Impact and Challenges of Software in 2025: Collected Papers

Today (2014), software is the key ingredient of most products and services. Software generates innovation and progress in many modern industries. Software is an indispensable element of evolution, of quality of life, and of our future. Software development is (slowly) evolving from a craft to an industrial discipline. Software – and the ability to efficiently produce and evolve high-quality software – is the single most important success factor for many highly competitive industries. Software technology, development methods and tools, and applications in more and more areas are rapidly evolving. The impact of software in 2025 in nearly all areas of life, work, relationships, culture, and society is expected to be massive. The question of the future of software is therefore important. However – like all predictions – quite difficult. Some market forces, industrial developments, social needs, and technology trends are visible today. How will they develop and influence the software we will have in 2025?:Impact of Heterogeneous Processor Architectures and Adaptation Technologies on the Software of 2025 (Kay Bierzynski) 9 Facing Future Software Engineering Challenges by Means of Software Product Lines (David Gollasch) 19 Capabilities of Digital Search and Impact on Work and Life in 2025 (Christina Korger) 27 Transparent Components for Software Systems (Paul Peschel) 37 Functionality, Threats and Influence of Ubiquitous Personal Assistants with Regard to the Society (Jonas Rausch) 47 Evolution-driven Changes of Non-Functional Requirements and Their Architecture (Hendrik Schön) 5

Business Role-Object Specification: A Language for Behavior-aware Structural Modeling of Business Objects

Representing and reusing the business objects of a domain model for various use cases can be difficult. Especially, if the domain model is acting as a template or a guideline, it is necessary to map the enterprise’s individual structure and processes on the shared domain model. Structural modeling languages often do not meet this requirement of reusing structures and complying to established processes. We propose a modeling language called BROS (Business Role-Object Specification) for describing the business objects’ structure and behavior for structural models, based on a given domain model and process models. It utilizes roles for a use case related specification of business objects as well as events as interfaces for the business processes affecting these roles. Thus, we are able to represent and adapt the business object in different contexts with individual requirements, without changing the underlying domain model. We demonstrate our approach by modeling a simple case

Autonomic Computing: State of the Art - Promises - Impact

Software has never been as important as today – and its impact on life, work and society is growing at an impressive rate. We are in the flow of a software-induced transformation of nearly all aspects of our way of life and work. The dependence on software has become almost total. Malfunctions and unavailability may threaten vital areas of our society, life and work at any time. The two massive challenges of software are one hand the complexity of the software and on the other hand the disruptive environment. Complexity of the software is a result of the size, the continuously growing functionality, the more complicated technology and the growing networking. The unfortunate consequence is that complexity leads to many problems in design, development, evolution and operation of software-systems, especially of large software-systems. All software-systems live in an environment. Many of today’s environments can be disruptive and cause severe problems for the systems and their users. Examples of disruptions are attacks, failures of partner systems or networks, faults in communications or malicious activities. Traditionally, both growing complexity and disruptions from the environment have been tackled by better and better software engineering. The development and operating processes are constantly being improved and more powerful engineering tools are introduced. For defending against disruptions, predictive methods – such as risk analysis or fault trees – are used. All this techniques are based on the ingenuity, experience and skills of the engineers! However, the growing complexity and the increasing intensity of possible disruptions from the environment make it more and more questionable, if people are really able to successfully cope with this raising challenge in the future. Already, serious research suggests that this is not the case anymore and that we need assistance from the software-systems themselves! Here enters “autonomic computing” – A promising branch of software science which enables software-systems with self-configuring, self-healing, self-optimization and self-protection capabilities. Autonomic computing systems are able to re-organize, optimize, defend and adapt themselves with no real-time human intervention. Autonomic computing relies on many branches of science – especially computer science, artificial intelligence, control theory, machine learning, multi-agent systems and more. Autonomic computing is an active research field which currently transfers many of its results into software engineering and many applications. This Hauptseminar offered the opportunity to learn about the fascinating technology “autonomic computing” and to do some personal research guided by a professor and assisted by the seminar peers.:Introduction 5 1 What Knowledge Does a Taxi Need? – Overview of Rule Based, Model Based and Reinforcement Learning Systems for Autonomic Computing (Anja Reusch) 11 2 Chancen und Risiken von Virtual Assistent Systemen (Felix Hanspach) 23 3 Evolution einer Microservice Architektur zu Autonomic Computing (Ilja Bauer) 37 4 Mögliche Einflüsse von autonomen Informationsdiensten auf ihre Nutzer (Jan Engelmohr) 49 5 The Benefits of Resolving the Trust Issues between Autonomic Computing Systems and their Users (Marc Kandler) 6

Autonomic Computing: State of the Art - Promises - Impact

Software has never been as important as today – and its impact on life, work and society is growing at an impressive rate. We are in the flow of a software-induced transformation of nearly all aspects of our way of life and work. The dependence on software has become almost total. Malfunctions and unavailability may threaten vital areas of our society, life and work at any time. The two massive challenges of software are one hand the complexity of the software and on the other hand the disruptive environment. Complexity of the software is a result of the size, the continuously growing functionality, the more complicated technology and the growing networking. The unfortunate consequence is that complexity leads to many problems in design, development, evolution and operation of software-systems, especially of large software-systems. All software-systems live in an environment. Many of today’s environments can be disruptive and cause severe problems for the systems and their users. Examples of disruptions are attacks, failures of partner systems or networks, faults in communications or malicious activities. Traditionally, both growing complexity and disruptions from the environment have been tackled by better and better software engineering. The development and operating processes are constantly being improved and more powerful engineering tools are introduced. For defending against disruptions, predictive methods – such as risk analysis or fault trees – are used. All this techniques are based on the ingenuity, experience and skills of the engineers! However, the growing complexity and the increasing intensity of possible disruptions from the environment make it more and more questionable, if people are really able to successfully cope with this raising challenge in the future. Already, serious research suggests that this is not the case anymore and that we need assistance from the software-systems themselves! Here enters “autonomic computing” – A promising branch of software science which enables software-systems with self-configuring, self-healing, self-optimization and self-protection capabilities. Autonomic computing systems are able to re-organize, optimize, defend and adapt themselves with no real-time human intervention. Autonomic computing relies on many branches of science – especially computer science, artificial intelligence, control theory, machine learning, multi-agent systems and more. Autonomic computing is an active research field which currently transfers many of its results into software engineering and many applications. This Hauptseminar offered the opportunity to learn about the fascinating technology “autonomic computing” and to do some personal research guided by a professor and assisted by the seminar peers.:Introduction 5 1 What Knowledge Does a Taxi Need? – Overview of Rule Based, Model Based and Reinforcement Learning Systems for Autonomic Computing (Anja Reusch) 11 2 Chancen und Risiken von Virtual Assistent Systemen (Felix Hanspach) 23 3 Evolution einer Microservice Architektur zu Autonomic Computing (Ilja Bauer) 37 4 Mögliche Einflüsse von autonomen Informationsdiensten auf ihre Nutzer (Jan Engelmohr) 49 5 The Benefits of Resolving the Trust Issues between Autonomic Computing Systems and their Users (Marc Kandler) 6

Cognitive Computing: Collected Papers

Cognitive Computing' has initiated a new era in computer science. Cognitive computers are not rigidly programmed computers anymore, but they learn from their interactions with humans, from the environment and from information. They are thus able to perform amazing tasks on their own, such as driving a car in dense traffic, piloting an aircraft in difficult conditions, taking complex financial investment decisions, analysing medical-imaging data, and assist medical doctors in diagnosis and therapy. Cognitive computing is based on artificial intelligence, image processing, pattern recognition, robotics, adaptive software, networks and other modern computer science areas, but also includes sensors and actuators to interact with the physical world. Cognitive computers – also called 'intelligent machines' – are emulating the human cognitive, mental and intellectual capabilities. They aim to do for human mental power (the ability to use our brain in understanding and influencing our physical and information environment) what the steam engine and combustion motor did for muscle power. We can expect a massive impact of cognitive computing on life and work. Many modern complex infrastructures, such as the electricity distribution grid, railway networks, the road traffic structure, information analysis (big data), the health care system, and many more will rely on intelligent decisions taken by cognitive computers. A drawback of cognitive computers will be a shift in employment opportunities: A raising number of tasks will be taken over by intelligent machines, thus erasing entire job categories (such as cashiers, mail clerks, call and customer assistance centres, taxi and bus drivers, pilots, grid operators, air traffic controllers, …). A possibly dangerous risk of cognitive computing is the threat by “super intelligent machines” to mankind. As soon as they are sufficiently intelligent, deeply networked and have access to the physical world they may endanger many areas of human supremacy, even possibly eliminate humans. Cognitive computing technology is based on new software architectures – the “cognitive computing architectures”. Cognitive architectures enable the development of systems that exhibit intelligent behaviour.:Introduction 5 1. Applying the Subsumption Architecture to the Genesis Story Understanding System – A Notion and Nexus of Cognition Hypotheses (Felix Mai) 9 2. Benefits and Drawbacks of Hardware Architectures Developed Specifically for Cognitive Computing (Philipp Schröppe)l 19 3. Language Workbench Technology For Cognitive Systems (Tobias Nett) 29 4. Networked Brain-based Architectures for more Efficient Learning (Tyler Butler) 41 5. Developing Better Pharmaceuticals – Using the Virtual Physiological Human (Ben Blau) 51 6. Management of existential Risks of Applications leveraged through Cognitive Computing (Robert Richter) 6

Management of MDR-TB in HIV co-infected patients in Eastern Europe: Results from the TB: HIV study

Objectives: Mortality among HIV patients with tuberculosis (TB) remains high in Eastern Europe (EE), but details of TB and HIV management remain scarce. Methods: In this prospective study, we describe the TB treatment regimens of patients with multi-drug resistant (MDR) TB and use of antiretroviral therapy (ART). Results: A total of 105 HIV-positive patients had MDR-TB (including 33 with extensive drug resistance) and 130 pan-susceptible TB. Adequate initial TB treatment was provided for 8% of patients with MDR-TB compared with 80% of those with pan-susceptible TB. By twelve months, an estimated 57.3% (95%CI 41.5-74.1) of MDR-TB patients had started adequate treatment. While 67% received ART, HIV-RNA suppression was demonstrated in only 23%. Conclusions: Our results show that internationally recommended MDR-TB treatment regimens were infrequently used and that ART use and viral suppression was well below the target of 90%, reflecting the challenging patient population and the environment in which health care is provided. Urgent improvement of management of patients with TB/HIV in EE, in particular for those with MDR-TB, is needed and includes widespread access to rapid TB diagnostics, better access to and use of second-line TB drugs, timely ART initiation with viral load monitoring, and integration of TB/HIV care

The Incidence of AIDS-Defining Illnesses at a Current CD4 Count ≥200 Cells/µL in the Post-Combination Antiretroviral Therapy Era

The incidence of AIDS was higher in patients with a current CD4 count of 500-749 cells/µL compared to 750-999 cells/µL, but did not decrease further at higher CD4 levels. Results were similar in those virologically suppressed on combination antiretroviral therapy, suggesting immune reconstitution is incomplete until CD4 >750/µ

Acute Muscular Sarcocystosis: An International Investigation Among Ill Travelers Returning From Tioman Island, Malaysia, 2011-2012

A large outbreak of acute muscular sarcocystosis (AMS) among international tourists who visited Tioman Island, Malaysia, is described. Clinicians evaluating travelers returning ill from Malaysia with myalgia, with or without fever, should consider AMS in their differential diagnosi

School Effects on the Wellbeing of Children and Adolescents

Well-being is a multidimensional construct, with psychological, physical and social components. As theoretical basis to help understand this concept and how it relates to school, we propose the Self-Determination Theory, which contends that self-determined motivation and personality integration, growth and well-being are dependent on a healthy balance of three innate psychological needs of autonomy, relatedness and competence. Thus, current indicators involve school effects on children’s well-being, in many diverse modalities which have been explored. Some are described in this chapter, mainly: the importance of peer relationships; the benefits of friendship; the effects of schools in conjunction with some forms of family influence; the school climate in terms of safety and physical ecology; the relevance of the teacher input; the school goal structure and the implementation of cooperative learning. All these parameters have an influence in promoting optimal functioning among children and increasing their well-being by meeting the above mentioned needs. The empirical support for the importance of schools indicates significant small effects, which often translate into important real-life effects as it is admitted at present. The conclusion is that schools do make a difference in children’s peer relationships and well-being