Comparative analysis of export demand for manufactures in the euro area countries

Artículo de revist

Wnt Signaling as a Master Regulator of Immune Tolerance in a Tumor Microenvironment

Aberrant Wnt signaling is a hallmark of many cancer types such as colon cancer. However, the effect of altered Wnt signaling is not only restricted to cancer cells but also dynamically interacts with a tumor microenvironment and has the ability to directly regulate the anti-tumor immune response. It has been reported that tumors induce immune tolerance through the activation of canonical Wnt signaling in dendritic cells promoting T regulatory responses, and also that both canonical and noncanonical Wnt proteins program dendritic cell responses for tolerance. Thus, the Wnt signaling pathway may be a novel and promising therapeutic target for anticancer immunotherapy. In this review, we will discuss the molecular mechanisms involved in immune cell response regulation mediated by canonical and noncanonical Wnt signaling

Gender diversity, inclusive innovation and firm performance

This study delves into intra-organizational dimensions that might impact inclusive innovation. Based on the expectation states theory, we explore how gender diversity in management positions and on the board of directors affects inclusive innovation. Furthermore, drawing on the signaling theory, we examine the relationship between inclusive innovation and a firm's performance. Using a comprehensive panel data of European manufacturing companies for a period of 10 years, we provide evidence that gender diversity in management positions and the presence of at least one woman on the board of directors have a positive effect on inclusive innovation. Our results also reveal the economic value of such strategy, showing that inclusive innovation positively influences performance. Implications for theory and managerial practice are discussedMinisterio de Ciencia e Innovaci on, Grant/Award Number: PID2020-117313RB-I00Ministerio de Ciencia e Innovaci on, Grant/Award Number: PID2020-117313RB-I00Programa Operativo Andalucia FEDER 2012-202

Determination of manufacturing exports in the euro area countries using a supply-demand model

Artículo de revist

Bottom-of-the-pyramid innovations: the impact of gender diversity.

This study is aimed at exploring the factors that can promote the fulfilment of the “bottom-of-the-pyramid” approach (BoP). We focus on the intra-organizational dimensions that might impact inclusive innovation developed by firms. Given that managers and upper echelons are responsible for resource allocation and strategic decisions, they have a key role to play in fostering inclusive innovation. Therefore, we explore: (i) the influence of gender diversity in management positions and on the board of directors (BoD) in the deployment of inclusive innovation; (ii) the relationship between inclusive innovation and a company’s performance. Multiple theories support the effect of gender diversity on corporate governance. This study is based on the expectation states theory (EST), and the signalling theory. Drawing on the EST, we argue that the presence of women in management positions is identified with higher expectations given their competences and performance in social matters, such as inclusive innovation. In turn, the second theoretical lens, the signalling theory, explains inclusive innovation as an external signal for stakeholders. Thus, they identify inclusive innovation as a company's commitment to the BoP, allowing the firm to obtain better results. We study a panel dataset of European public manufacturing firms for the period 2008-2017. Our findings reveal that gender diversity in management positions and the presence of at least one woman on the BoD have a positive effect on inclusive innovation. Furthermore, our results also highlight the economic value of such strategy. By measuring its impact on business results, we provide evidence that inclusive innovation positively influences performance. This result is worthy to overcome the traditional assumption regarding the trade-off between social and economic value creation goals in firms.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Simulation and flavor compound analysis of dealcoholized beer via one-step vacuum distillation

Producción CientíficaThe coupled operation of vacuum distillation process to produce alcohol free beer at laboratory scale and Aspen HYSYS simulation software was studied to define the chemical changes during the dealcoholization process in the aroma profiles of 2 different lager beers. At the lab-scale process, 2 different parameters were chosen to dealcoholize beer samples, 102 mbar at 50 °C and 200 mbar at 67 °C. Samples taken at different steps of the process were analyzed by HS-SPME–GC–MS focusing on the concentration of 7 flavor compounds, 5 alcohols and 2 esters. For simulation process, the EoS parameters of the Wilson-2 property package were adjusted to the experimental data and one more pressure was tested (60 mbar). Simulation methods represent a viable alternative to predict results of the volatile compound composition of a final dealcoholized beer.Junta de Castilla y León (programa de apoyo a proyectos de investigación – Ref. VA330U13

Determinación de cafeína en café mediante cromatografía líquida de alta resolución (HPLC)

La determinación de cafeína es un procedimiento muy empleado para la caracterización de ciertos alimentos que contienen cafeína de manera natural como son el café, el cacao o el té, y también para el control de calidad en ciertos donde la cafeína se emplea como ingrediente, como son los refrescos y las bebidas energéticas, , En este artículo vamos a describir un procedimiento analítico utilizado para la determinación de cafeína empleando cromatografía líquida de alta resolución (HPLC) en fase reversa y detección UV.Fuentes López, A.; Fuentes López, C.; García Martínez, EM. (2018). Determinación de cafeína en café mediante cromatografía líquida de alta resolución (HPLC). http://hdl.handle.net/10251/104563DE

Robótica, realidad aumentada y TAC como herramientas clave en la metodología CLIL en Educación Infantil

In this article we present a class innovative experience where we work on CLIL methodology (Content and Language Integrated Learning) in preschool education by means of Information and Communication Technologies. The main objective of this experience is to develop CLIL methodology together with a project-based approach and introducing robots and augmented reality as a source of knowledge.  By means of using CLIL and projects, we develop linguistic competence on students and we work on content in a more meaningful way.Presentamos en este artículo una experiencia de aula en la que se trabaja la  metodología CLIL (Content and Language Integrated Learning) en educación infantil utilizando las nuevas tecnologías como recurso educativo. El objetivo principal de dicha experiencia es llevar la metodología CLIL a los proyectos de trabajo que los alumnos/as ya estén realizando en su lengua materna y emplear las TAC como recursos clave para el desarrollo de las habilidades comunicativas del alumnado. De esta forma, el aprendizaje de los contenidos propios del currículum y el desarrollo de la competencia en la lengua extranjera se realizan de forma paralela, sin ningún tipo de división temporal, espacial o didáctic

Primary production, carbon release, and respiration during spring bloom in the Baltic Sea

We determined the gross and net primary production (GPP and NPP) for the total community and the < 10 μ m size fraction, the net release of dissolved organic carbon (DOC), and the microbial respiration in the Baltic Sea during the spring bloom. Samples ( n  = 126) were taken from the surface (3 m depth) covering most subbasins and different phases of the bloom, defined by the inorganic nutrient and Chlorophyll a (Chl a ) concentrations. During the course of the bloom, the NPP rate (i.e., growth rate) decreased from 0.34 d −1  ± 0.03 (SE) to 0.15 d −1  ± 0.02 (SE), the contribution of the < 10 μ m fraction increased from 14% ± 2.5 (SE) to 47% ± 4.0 (SE) and the percent extracellular release (PER) increased from 3.8% ± 0.7 (SE) to 8.9% ± 1.5 (SE). The assimilation number, was on average 0.13 mol C (g Chl a ) −1 h −1  ± 0.01 (SE), and the average GPP:NPP rate was 1.25. The respiration increased with growth rate and was 21% of the GPP rate. The net release of DOC was relatively constant over the bloom phases, with increasing PER compensating for the reduction in biomass, and estimated to 24–36  μ mol DOC L −1 during the whole spring bloom period in all subbasins except in the Bay of Bothnia where it was 75% lower. The assimilation number was surprisingly stable, suggesting it is uncoupled from the inorganic nutrient concentration, likely a reflection of physiological acclimation and changing phytoplankton community.Academy of Finland | Ref. 259164Walter ja Andrée de Nottbeckin Sääti

Evolución criminológica, penal y penitenciaria en Cataluña desde la Reforma del Código Penal. Estudio estadístico-descriptivo.

El presente artículo surge como resultado de la recopilación de datos llevada a cabo por el equipo investigador del Observatorio del Sistema Penal y los Derechos Humanos de la Universidad de Barcelona (OSPDH), en el marco de la investigación: "¿Resocialización o incapacitación?: Sostenibilidad del Sistema Penitenciario español ante las nuevas realidades delictivas y demandas de seguridad"[1]. A lo largo del proceso de recogida de información el equipo investigador del OSPDH, fue constatando la existencia de evidencias estadísticas que ponían de manifiesto la evolución y los cambios experimentados en el sistema penitenciario catalán durante los últimos veinte años, identificándose una estrecha relación entre los mismos y los diversos periodos político-económicos vividos en el conjunto del Estado español desde la reforma del Código Penal de1995 hasta la actualidad[2]. [1] El presente trabajo se ha realizado en el marco del Proyecto de Investigación I+D+i: '¿RESOCIALIZACIÓN O INCAPACITACIÓN? SOSTENIBILIDAD DEL SISTEMA PENITENCIARIO ESPAÑOL ANTE LAS NUEVAS REALIDADES DELICTIVAS Y DEMANDAS DE SEGURIDAD, con referencia DER2011-27337, del Ministerio de Economía y Competitividad. [2] Periodos que son desarrollados en este mismo Monográfico en el artículo de Brandariz (2015), titulado: La evolución del sistema penitenciario español, 1995-2014: transformaciones de la penalidad y modificación práctica de la realidad penitenciaria