Cattle handling technique can induce fatigued cattle syndrome in cattle not fed a beta adrenergic agonist

Citation: Frese, D. A., Reinhardt, C. D., Bartle, S. J., Rethorst, D. N., Hutcheson, J. P., Nichols, W. T., . . . Thomson, D. U. (2016). Cattle handling technique can induce fatigued cattle syndrome in cattle not fed a beta adrenergic agonist. Journal of Animal Science, 94(2), 581-591. doi:10.2527/jas2015-9824Angus crossbred steers (n = 40; 563 +/- 44 kg) were used to examine the effects of handling method and fat thickness on the blood chemistry and physiology of market steers. Steers were blocked by backfat (BF) thickness and were randomly assigned to treatment groups: low-stress handling (LSH) and aggressive handling (AH). Cattle were then ran-domly assigned to one of 5 blocks containing 4 steers from the LSH and AH treatments. Steers in the LSH treatment were walked and AH cattle were run through a course of 1,540 m. Blood samples were obtained via jugular venipuncture before handling (BASE), at 770 m (LAP1), at 1,540 m (LAP2), and at1 h (1H) and 2 h (2H) after finishing the course. Blood samples were analyzed for plasma lactate (LAC), creatinine kinase (CK), base excess (BE), blood pH (pH), serum cortisol (CORT) concentrations, and venous carbon dioxide (PvCO2) and oxygen (PvO2) pressures. Heart rate (HR), respiratory rate (RR), and rectal temperature (TEMP) were measured at the same intervals. Cattle in the AH treatment had greater (P 0.14). Blood pH in AH cattle was decreased compared with that in LSH cattle (P 0.13) at BASE, 1H, or 2H. Heart rate and TEMP were increased in AH cattle compared to LSH (P > 0.01). Serum cortisol was increased (P < 0.05) in AH compared to that in LSH cattle at LAP1 (87.5 vs. 58.9 nmol/ L), LAP2 (144.4 vs. 93.1 nmol/ L), and 1H (113.5 vs. 53.1 nmol/ L). Although RR was not differ-ent between LSH and AH, PvCO2 was decreased in AH compared to that in LSH (P < 0.05) at LAP2 (30.6 vs. 39.3 mmHg) and PvO2 was increased at LAP1 (42.7 vs. 33.5 mmHg) and at LAP2 (51.5 vs. 36.6 mmHg). Lactate was increased in AH cattle in the thicker BF group at 1H (P < 0.05), and blood pH was decreased at LAP1, LAP2, and 1H (P < 0.05) compared to the thinner BF cohorts. Four AH steers became exhausted (EXH) and did not complete the course. Increased CK, decreased PvCO2, and muscle tremors occurred in EXH steers compared to non-exhausted AH cohorts. Results of this study show that AH causes physiologic and blood chemistry changes in steers, which can be potentially detrimental to cattle, emphasizing the need for lowstress handling practices

Efeitos de diferentes níveis de desfolha nos estádios vegetativo e reprodutivo sobre desenvolvimento da cultura da soja.

JIPE 2013

Eficiência de inseticidas, quando aplicados nas sementes de soja, associados ou não com produtos aplicados na parte aérea, no controle de pragas foliares na cultura.

JIPE 2013

DEVELOPMENT OF NAVY ACQUISITION PROFESSIONALS IN COLLABORATION WITH THE NAVY JUNIOR OFFICER COUNCIL

In coordination with the Navy Junior Officer Council (NJOC), this project examines implementation of a pilot program that U.S. Navy Supply Corps Junior Officers (JOs) attend the distance learning Master of Science in Contract Management (MSCM) program as part of their two-year Navy Acquisition Contracting Officer internship. Attending the MSCM program provides JOs with the opportunity to meet two crucial career milestones, earning both a master’s degree and achieving a Defense Acquisition University (DAU) certification in contracting. JO attendance in the MSCM program would be in place of attending the DAU residency courses necessary for the current DAU Level I/II contracting certification.Lieutenant, United States NavyApproved for public release. Distribution is unlimited

Quantum computing in optical microtraps based on the motional states of neutral atoms

We investigate quantum computation with neutral atoms in optical microtraps where the qubit is implemented in the motional states of the atoms, i.e., in the two lowest vibrational states of each trap. The quantum gate operation is performed by adiabatically approaching two traps and allowing tunneling and cold collisions to take place. We demonstrate the capability of this scheme to realize a square-root of swap gate, and address the problem of double occupation and excitation to other unwanted states. We expand the two-particle wavefunction in an orthonormal basis and analyze quantum correlations throughout the whole gate process. Fidelity of the gate operation is evaluated as a function of the degree of adiabaticity in moving the traps. Simulations are based on rubidium atoms in state-of-the-art optical microtraps with quantum gate realizations in the few tens of milliseconds duration range.Comment: 11 pages, 7 figures, for animations of the gate operation, see http://www.itp.uni-hannover.de/~eckert/na/index.htm

Optical dipole traps and atomic waveguides based on Bessel light beams

We theoretically investigate the use of Bessel light beams generated using axicons for creating optical dipole traps for cold atoms and atomic waveguiding. Zeroth-order Bessel beams can be used to produce highly elongated dipole traps allowing for the study of one-dimensional trapped gases and realization of a Tonks gas of impentrable bosons. First-order Bessel beams are shown to be able to produce tight confined atomic waveguides over centimeter distances.Comment: 20 pages, 5 figures, to appear in Phys. Rev.

Willing and able: action-state orientation and the relation between procedural justice and employee cooperation

Existing justice theory explains why fair procedures motivate employees to adopt cooperative goals, but it fails to explain how employees strive towards these goals. We study self-regulatory abilities that underlie goal striving; abilities that should thus affect employees’ display of cooperative behavior in response to procedural justice. Building on action control theory, we argue that employees who display effective self-regulatory strategies (action oriented employees) display relatively strong cooperative behavioral responses to fair procedures. A multisource field study and a laboratory experiment support this prediction. A subsequent experiment addresses the process underlying this effect by explicitly showing that action orientation facilitates attainment of the cooperative goals that people adopt in response to fair procedures, thus facilitating the display of actual cooperative behavior. This goal striving approach better integrates research on the relationship between procedural justice and employee cooperation in the self-regulation and the work motivation literature. It also offers organizations a new perspective on making procedural justice effective in stimulating employee cooperation by suggesting factors that help employees reach their adopted goals

CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer

Pancreatic ductal adenocarcinoma (PDA) is characterized by abundant desmoplasia and poor tissue perfusion. These features are proposed to limit the access of therapies to neoplastic cells and blunt treatment efficacy. Indeed, several agents that target the PDA tumor microenvironment promote concomitant chemotherapy delivery and increased antineoplastic response in murine models of PDA. Prior studies could not determine whether chemotherapy delivery or microenvironment modulation per se were the dominant features in treatment response, and such information could guide the optimal translation of these preclinical findings to patients. To distinguish between these possibilities, we used a chemical inhibitor of cytidine deaminase to stabilize and thereby artificially elevate gemcitabine levels in murine PDA tumors without disrupting the tumor microenvironment. Additionally, we used the FG-3019 monoclonal antibody (mAb) that is directed against the pleiotropic matricellular signaling protein connective tissue growth factor (CTGF/CCN2). Inhibition of cytidine deaminase raised the levels of activated gemcitabine within PDA tumors without stimulating neoplastic cell killing or decreasing the growth of tumors, whereas FG-3019 increased PDA cell killing and led to a dramatic tumor response without altering gemcitabine delivery. The response to FG-3019 correlated with the decreased expression of a previously described promoter of PDA chemotherapy resistance, the X-linked inhibitor of apoptosis protein. Therefore, alterations in survival cues following targeting of tumor microenvironmental factors may play an important role in treatment responses in animal models, and by extension in PDA patients

Горизонтальные классификаторы. Основы теории и расчета: моногр.

Приведены технологические схемы получения строительных песков при гидромеханизированной добыче, основные конструктивные схемы классификаторов, используемых при получении строительных песков. Особое внимание уделено изучению процесса взаимодействия проточной части горизонтального классификатора с совокупностью твердых частиц, расположенных в горизонтальном ускоренном потоке несущей среды. Выполнено математическое моделирование ускоренного движения горизонтального потока и твердых частиц в пределах разнонаклонных поверхностей горизонтального классификатора. Экспериментально изучено гравитационное осаждение твердых частиц, рассмотренное в виде вертикальной и горизонтальной составляющих, а также влияние стесненности движения и перемещения твердых частиц относительно несущего горизонтального потока. Приведена методика расчета и выбора параметров классификаторов, информация об опыте проектирования и внедрения горизонтальных классификаторов в составе добычных комплексов при освоении обводненных месторождений песков. Монография может быть полезна студентам, инженерно-техническим работникам, сотрудникам высших учебных заведений, научно-исследовательских институтов и проектных организаций горной промышленности