38 research outputs found
A política pública do uso do nome social por travestis e transexuais nas escolas municipais de Belo Horizonte: uma pesquisa documental
Este artigo é o relato de uma pesquisa acadêmica, financiada pelo FIP/PUC Minas, que investigou a política pública do uso do nome social por estudantes travestis e transexuais nas escolas municipais de Belo Horizonte. Por nome social, entende-se o nome pelo qual travestis e transexuais preferem ser chamados cotidianamente, uma vez que o nome civil ou de registro não reflete sua identidade de gênero. A pesquisa teve suporte epistemológico nas teorias pós-estruturalistas de gênero e como estratégia metodológica a análise documental da Resolução CME/BH nº 002/08 e do Parecer CME/BH nº 052/08, ambos do Conselho Municipal de Educação de Belo Horizonte, que legitimam o uso do nome social na educação. Inúmeras inconsistências textuais e conceituais foram encontradas nos documentos analisados, comprometendo a lógica interna do dispositivo legal. Entretanto, longe de ser o ideal, o nome social trouxe a temática para a pauta política dos direitos humanos.Palavras chave: Direitos humanos; Educação; Gênero; Nome social; Política pública.
Insecticidal Activity of [Cu(H2NTA)2].2H2O in Aedes aegypti Larvae (Diptera: Culicidae)
The demand for new insecticides and alternative strategies for the population control of Aedes aegypti has stimulated research to obtain new compounds with broad biological activity. Accordingly, the dihydrogen nitrilotriacetate complex of copper (II) dihydrate, [Cu(H2NTA)2].2H2O, was synthesized by the stoichiometric reaction of nitrilotriacetic acid (H3NTA) hydroxide with basic copper carbonate (II) (Cu2(OH)2CO3) and characterized by the spectroscopic techniques UV-Vis and FT-IR. The biological toxicity in A. aegypti was determined by bioassay using concentrations ranging from 90.0 mg L−1 to 897.4 mg L−1. The LC50 obtained was 146.11 mg L−1 [132.18–160.10] and the LT50 obtained at a concentration of 897.4 mg L−1 was 70.61 min [38.21–94.90]. The results showed that the complex obtained in this work is a potential metal-insecticide.
DOI: http://dx.doi.org/10.17807/orbital.v7i4.73
Insecticidal Activity of [Cu(H2NTA)2].2H2O in Aedes aegypti Larvae (Diptera: Culicidae)
The demand for new insecticides and alternative strategies for the population control of Aedes aegypti has stimulated research to obtain new compounds with broad biological activity. Accordingly, the dihydrogen nitrilotriacetate complex of copper (II) dihydrate, [Cu(H2NTA)2].2H2O, was synthesized by the stoichiometric reaction of nitrilotriacetic acid (H3NTA) hydroxide with basic copper carbonate (II) (Cu2(OH)2CO3) and characterized by the spectroscopic techniques UV-Vis and FT-IR. The biological toxicity in A. aegypti was determined by bioassay using concentrations ranging from 90.0 mg L−1 to 897.4 mg L−1. The LC50 obtained was 146.11 mg L−1 [132.18–160.10] and the LT50 obtained at a concentration of 897.4 mg L−1 was 70.61 min [38.21–94.90]. The results showed that the complex obtained in this work is a potential metal-insecticide.
DOI: http://dx.doi.org/10.17807/orbital.v7i4.73
In Vivo Approaches Reveal a Key Role for DCs in CD4+ T Cell Activation and Parasite Clearance during the Acute Phase of Experimental Blood-Stage Malaria
Dendritic cells (DCs) are phagocytes that are highly specialized for antigen presentation. Heterogeneous populations of macrophages and DCs form a phagocyte network inside the red pulp (RP) of the spleen, which is a major site for the control of blood-borne infections such as malaria. However, the dynamics of splenic DCs during Plasmodium infections are poorly understood, limiting our knowledge regarding their protective role in malaria. Here, we used in vivo experimental approaches that enabled us to deplete or visualize DCs in order to clarify these issues. To elucidate the roles of DCs and marginal zone macrophages in the protection against blood-stage malaria, we infected DTx (diphtheria toxin)-treated C57BL/6.CD11c-DTR mice, as well as C57BL/6 mice treated with low doses of clodronate liposomes (ClLip), with Plasmodium chabaudi AS (Pc) parasites. The first evidence suggesting that DCs could contribute directly to parasite clearance was an early effect of the DTx treatment, but not of the ClLip treatment, in parasitemia control. DCs were also required for CD4+ T cell responses during infection. The phagocytosis of infected red blood cells (iRBCs) by splenic DCs was analyzed by confocal intravital microscopy, as well as by flow cytometry and immunofluorescence, at three distinct phases of Pc malaria: at the first encounter, at pre-crisis concomitant with parasitemia growth and at crisis when the parasitemia decline coincides with spleen closure. In vivo and ex vivo imaging of the spleen revealed that DCs actively phagocytize iRBCs and interact with CD4+ T cells both in T cell-rich areas and in the RP. Subcapsular RP DCs were highly efficient in the recognition and capture of iRBCs during pre-crisis, while complete DC maturation was only achieved during crisis. These findings indicate that, beyond their classical role in antigen presentation, DCs also contribute to the direct elimination of iRBCs during acute Plasmodium infection.São Paulo Research Foundation grants: (2011/24038-1 [MRDL], 2009/08559-1 [HBdS], CAPES/IGC 04/
2012 [MRDL, CET])
Caderno de pós-graduação em direito: novas tendências do direito ambiental
Pioneirismo sempre foi uma característica do UniCEUB; outra característica
é a evolução permanente. A Instituição sempre acompanhou a evolução
tecnológica e pedagógica do ensino. Isso se coaduna com a filosofia institucional
que é a de preparar o homem integral por meio da busca do conhecimento e
da verdade, assegurando-lhe a compreensão adequada de si mesmo e de sua responsabilidade
social e profissional. Destarte, a missão institucional é a de gerar, sistematizar
e disseminar o conhecimento visando à formação de cidadãos reflexivos e empreendedores,
comprometidos com o desenvolvimento socioeconômico sustentável.
E não poderia ser diferente. Com a expansão do conteúdo acadêmico que se
transpassa do físico para o virtual, do local para o universal, do restrito para o difundido,
isso porque o papel não é mais apenas uma substância constituída por elementos
fibrosos de origem vegetal, os quais formam uma pasta que se faz secar sob a forma de
folhas delgadas donde se cria, modifica, transforma letras em palavras; palavras em textos;
textos em conhecimento, não! O papel se virtualiza, se desenvolve, agora, no infinito,
rebuscado de informações. Assim, o UniCEUB acompanha essa evolução. É dessa forma
que se desafia o leitor a compreender a atualidade, com a fonte que ora se entrega à leitura
virtual, chamada de e-book.
Isso é resultado do esforço permanente, da incorporação da ciência desenvolvida
no ambiente acadêmico, cujo resultado desperta emoção, um sentimento de beleza de
que o conteúdo científico representa o diferencial profissional.
Portanto, convido-os a leitura desta obra, que reúne uma sucessão de artigos que
são apresentados com grande presteza e maestria; com conteúdo forte e impactante; com
sentimento e método, frutos da excelência acadêmicaOrganizadores: Gabriel R. Rozendo Pinto, Leandro Soares Nunes, Naiara Ferreira Martins, Paulo Victor Lima, Pedro Almeida Costa, Pietro Pimenta, Rodrigo Gonçalves Ramos de Oliveir
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4
While the increasing availability of global databases on ecological communities has advanced our knowledge
of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In
the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of
Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus
crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced
environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian
Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by
2050. This means that unless we take immediate action, we will not be able to establish their current status,
much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio