12 research outputs found
Principles of 3D chromosome folding and evolutionary genome reshuffling in mammals.
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Studying the similarities and differences in genomic interactions between species provides fertile grounds for determining the evolutionary dynamics underpinning genome function and speciation. Here, we describe the principles of 3D genome folding in vertebrates and show how lineage-specific patterns of genome reshuffling can result in different chromatin configurations. We (1) identified different patterns of chromosome folding in across vertebrate species (centromere clustering versus chromosomal territories); (2) reconstructed ancestral marsupial and afrotherian genomes analyzing whole-genome sequences of species representative of the major therian phylogroups; (3) detected lineage-specific chromosome rearrangements; and (4) identified the dynamics of the structural properties of genome reshuffling through therian evolution. We present evidence of chromatin configurational changes that result from ancestral inversions and fusions/fissions. We catalog the close interplay between chromatin higher-order organization and therian genome evolution and introduce an interpretative hypothesis that explains how chromatin folding influences evolutionary patterns of genome reshuffling. [Abstract copyright: Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.
SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues
- Author
- Aarno Palotie
- Abdolmajid Hosseini
- Abdulaziz AlMalik
- Abdulraheem Alshareef
- Achille Iolascon
- Adam S. Butterworth
- Afshar Etemadi Aleagha
- Agnese Verzuri
- Agostino Ognibene
- Agostino Riva
- Ahmadreza Niavarani
- Ahna Girshick
- Aida Fiz-Lopez
- Alba Parra Martınez
- Albandary M. Alowayn
- Albert Tenesa
- Albert V. Smith
- Alessandra Guarnaccia
- Alessandra Renieri
- Alessandra Stella
- Alessandra Vergori
- Alessandro Pancrazzi
- Alessia Giorli
- Alex Serra-Llovich
- Alex Soriano
- Alex Stuckey
- Alexander Labkowsky
- Alexander T. Williams
- Alexander W. Charney
- Alexandra Aksentijevich
- Alexandre Belisle
- Ali Amirsavadkouhi
- Ali Sobh
- Alice Donati
- Alicia de Felipe Mimbrera
- Alicia R. Martin
- Alireza Adamsara
- Altaf Ali
- Amal Al Mutairi
- Amin K. Khattab
- Amr M. Yassen
- Amr Samir
- Amy Trankiem
- Anastasia Lucas
- Andre G. Uitterlinden
- Andrea Antinori
- Andrea Cossarizza
- Andrea Ganna
- Andrea Ganna
- Andrea Martın-Nalda
- Andrea Tommasi
- Andres Metspalu
- Andrew Beck
- Andrew P. Boughton
- Anil P. S. Ori
- Ann E. Woolley
- Anna Canaccini
- Anna Carreras
- Anna Dominguez-Mayoral
- Anna L. Guyatt
- Anna M. Planas
- Anna Maria Pinto
- Annarita Giliberti
- Anne E. Justice
- Anne Kallaste
- Anne Marie OâConnell
- Anne Richmond
- Anne Richmond
- Anne-Sophie Sauvage
- Annique Claringbould
- Anoud Albader
- Antonella DâArminio Monforte
- Antonella Vincenti
- Antonio Di Biagio
- Antonio Perrella Francesco Bianchi
- Anu Tamm
- Anurag Verma
- Archie Campbell
- Archie Campbell
- Arianna Emiliozzi
- Arianna Gabrieli
- Aris Baras
- Arthur Timothy D
- Asher Haug Baltzell
- Ashish Yadav
- Athanasios Kousathanas
- Attia A. S. Mohamed
- Aubrey Annis
- Augusto Rendon
- Avromie Karp
- Bader Alghamdi
- Bahareh Sharififard
- Bandar A. Suliman
- Barbara Rossetti
- Bari Britvan
- Bartlomiej P. Przychodzen
- Beatriz Cortes
- Beatriz Dietl
- Ben M. Brumpton
- Benjamin M. Neale
- Benoit Misset
- Bernard Lambermont
- Bhavi Trivedi
- Binglan Li
- Biswarup Ghosh
- BjĂžrn Olav Asvold
- Bluma Brenner
- Brett L. Collins
- Brooke Rhead
- Brooke Wolford
- Brooke Wolford
- Brooke Wolford Sebastian Zoš llner
- Bruno Frediani
- Carlo Rivolta
- Carlos Domingo
- Carlota Dobano
- Carmelo Piscopo
- Carmen Marciano
- Carolina Medina-Gomez
- Caroline Cusick
- Caroline Hayward
- Caroline Hayward
- Caterina Lo Rizzo
- Catherine A. Ball
- Catherine E. Bee
- Catherine John
- Cathy Voide
- Cesira Nencioni
- Charlotte Guzman
- Chiara Barbieri
- Chiara Batini
- Chiara Fallerini
- Chiara Gabbi
- Chiara Spertilli
- Chloe Fawns-Ritchie
- Chloe Fawns-Ritchie
- Chris C. A. Spencer
- Chris Tselios
- Christelle Meuris
- Christian Von Frenckell
- Christine Stevens
- Christine Stevens
- Christopher A. Odhams
- Christopher J. Griffiths
- Christopher J. OâDonnell
- Christopher R. Gignoux
- Christos Polymeropoulos
- Chureerat Phokaew
- Claire Churchhouse
- Claudia Suardi
- Claudio Ferri
- Clive Hoggart
- Cotton Seed
- CRiPSI
- Cristen Willer
- Cristina Mussini
- D'Antonio Matteo
- D'Antonio-Chronowska Agnieszka
- Daiana Aguero
- Dan Mason
- Daniel Auld
- Daniel E. Kaufmann
- Daniel I. Chasman
- Daniel J. Wilson
- Daniel King
- Daniel M. Jordan
- Daniel Rader
- Daniel Rhodes
- Daniela Francisci
- Danielle Henry
- Danilo Tacconi
- Danny Park
- Darin Adra
- Dave J. Carey
- David A. van Heel
- David Bennett
- David Bernardo
- David Dalmau
- David H. Wyllie
- David J. Porteous
- David J. Porteous
- David R. Morrison
- David Torrents
- Davide Grassi
- Davide Romani
- Deema AlZahrani
- Derrick W. Crook
- Dhryata Kamdar
- Diana Alaverdian
- Diego Ripamonti
- Dionysios Neofytos
- Doaa Shahin
- Domenico A. Coviello
- Dona Baraka
- Donatella Acquilini
- Dorota Pasko
- Douglas M. Shaw
- Duncan Emma
- Duncan S. Palmer
- Ebrahim S. Mahmoud
- Ebtehal Alsolm
- Eco (E. J. C. ) de geus
- Edoardo Conticini
- Edward J. Hollox
- Edward Laane
- Eimear E. Kenny
- Elena Andreucci
- Elena Bargagli
- Elena Desanctis
- Elena Jimenez-Xarrie
- Elena Muino
- Eliecer Coto
- Elisa Arribas
- Elisa Benetti
- Elisa Frullanti
- Elisabetta Menatti
- Elisabetta Schiaroli
- Elizabeth G. Atkinson
- Elizabeth W. Karlson
- Eman Barhoush
- Emanuele Catena
- Emanuele Di Angelantonio
- Emma F. Perez
- Emma L. Adams
- Ene Reimann
- Enrico Martinelli
- Eric E. Schadt
- Erik Solligard
- Erwin Schurr
- Esteban Lopera
- Esther Gonzalez-Villa
- Eugenia Quiros-Roldan
- Eurie L. Hong
- F. Kyle Satterstrom
- Fabio Lena
- Faisal Almalki
- Fatimah Alqubaishi
- Fawz Al Harthi
- Federica Gaia Miraglia
- Federico Anedda
- Federico Franchi
- Ferdinando Giannattasio
- FHoGID RegCOVID
- Filippo Aucella
- Filippo Biscarini
- FinnGen
- Floriana Valentino
- Francesca Andretta
- Francesca Fava
- Francesca Gatti
- Francesca Mari
- Francesca Montagnani
- Francesco Castelli
- Francesco Paciosi
- Francesco Paciosi
- Francesco Raimondi
- Francesco Vladimiro Segala
- Francisca Ruiz-Jaen
- Francisco Lozano
- Franco Maggiolo
- Frazer
- Frederic Frippiat
- G. Mark Lathrop
- Gabriella Coiro
- Gabriella Doddato
- Gabriella Maria Squeo
- Gavin Band
- Geetha Chittoor
- Gemma Castano-Vinyals
- Gemma Serrano-Heras
- Genes &
- Genevieve Roberts
- Genni Spargi
- Georgia Chan
- Giada Beligni
- Gian Piero Caldarelli
- Gianfranco Parati
- Gilles Darcis
- Gillian M. Belbin
- Gina Peloso
- Giordano Botta`
- Girish N. Nadkarni
- Gita A. Pathak
- Gita A. Pathak
- Giulianini Franco
- Giuseppe Fiorentino
- Giuseppe Merla
- Giusy Tiseo
- Gloria Pessina
- Goncalo R. Abecasis
- Gopal Sarma
- Guillaume Butler-Laporte
- Guillaume ButlerLaporte
- Guillermo M. Albaiceta
- Hadeel AlBardis
- Hakon Hakonarson
- Hakon Hakonarson
- Hamed Abdollahi
- Hani Al-Afghani
- Hannah Polikowski
- Hanteera S. Moahmed
- Harendra Guturu
- Health Research Team
- Helene Alavere
- Hengameh Ansari Tadi
- Hilary C. Martin
- Hilary Finucane
- Howard D. Sesso
- Hugo Zeberg
- Hung-Hsin Chen
- Huy Nguyen
- Ilaria Meloni
- Ilaria Rancan
- Iman Almohammed
- Immacolata Andolfo
- Inge Ringmets
- Irene Salib
- Irene van Blokland
- Isabella Zanella
- Israel Fernandez-Cadenas
- Ivan Galvan-Femenia
- J. Brent Richards
- J. Brent Richards
- J. Michael Gaziano
- Jaana Pesukova
- Jack A. Kosmicki
- Jacob Armstrong
- Jacqueline I. Goldstein
- Jahad Alghamdi
- Jaime Masjuan
- James B. Meigs
- James F. Wilson
- Jara Carcel-Marquez
- Jean-Baptiste Giot
- Jehad K. Albakri
- Jehan J. El-Jawhari
- Jekaterina Tabri
- Jennifer Below
- Jennifer E. Huffman
- Jennifer R. Harris
- Jessica Jacques
- Jiannis Ragoussis
- Jing Hua Zhao
- Jiongming Wang
- Joan Marti-Fabregas
- Joan Montaner Villalonga
- JoAnn E. Manson
- Joel Starkopf
- John Danesh
- John Wright
- Jonathan Afilalo
- Jonathan Grip
- Jonathan Shortt
- Jonathon LeFaive
- Jordan W. Smoller
- Jordi Perez-Tur
- Josep L. Bedini
- Josep Maria Mercader
- Josep Mercader
- Joseph B. Leader
- Joseph B. McCormick
- Joseph D. Buxbaum
- Joseph R. Glessner
- Joseph T. Glessner
- Jouke Jan Hottenga
- Juan Gomez
- Judith Garcia-Aymerich
- Judith. M. Vonk
- Judy H. Cho
- Juha Karjalainen
- Julie E. Buring
- Julie E. Horowitz
- Julien Guiot
- Julien Guntz
- Junghyun Jung
- Justine K. Rudkin
- Kai Kisand
- Kamal Okasha
- Karen A. Hunt
- Kari North
- Karolina Chwialkowska
- Katherine Keller
- Kathleen C. Barnes
- Kathrin Aprile von Hohenstaufen
- Kati Donner
- Kati Hensen
- Kati Kristiansson
- Katia Capitani
- Katja Kivinen
- Keith Noto
- Kelly A
- Kelly Cho
- Kenton DâMellow
- Kevin W. Li
- Konrad J. Karczewski
- Kristi Lall
- Kristi Niblo
- Kristian Hveem
- Kristin Rand
- Kristin Tsuo
- Kristina Zguro
- Kristjan Metsalu
- Kristy Crooks
- Kumar Veerapen
- Kumardeep Chaudhary
- Kyle Gettler
- Laetitia Laurent
- Laia Llucia-Carol
- Laila Al-Awdah
- Lara Lloret Iglesias
- Lara Tang
- Laura Bergantini
- Laura D. Venn
- Laura Di Sarno
- Laura G. Sloofman
- Laura M. Huckins
- Lauro Sumoy
- Leen Abu Safieh
- Leonardo Croci
- Leonardo Marquez
- Lia Crotti
- Liam L. Hiester
- Lili Milani
- Lill-Iren S. Trogstad
- Lindo Nkambul
- Lindokuhle Nkambul
- Lindokuhle Nkambul
- Lindokuhle Nkambule
- Lindokuhle Nkambule
- Lorenzo Salerni
- Louis Petitjean
- Louise V. Wain
- Loukas Moutsianas
- Luca Cantarini
- Luca Guidelli
- Luca Masucci
- Lude Franke Marike Boezen
- Luisa Tavecchia
- Luong Ruiz
- M. Arfan Ikram
- Maarja Lepamets
- Madeleine Durand
- Madonna M. Eltoukhy
- Maha Albeladi
- Mahmoud Abdel-Aziz
- Mairo Puusepp
- Malak Abedalthagafi
- Manal Alaamery
- Manolis Kogevinas
- Mansour Almutairi
- Manuel A. R. Ferreira
- Marc Afilalo
- Marcela Morris
- Marco Castori
- Marco Falcone
- Marco Feri
- Marco Gori
- Marco Mandala`
- Marco Rizzi
- Marco Tanfoni
- Marco Vecchia
- Margherita Baldassarri
- Mari E. K. Niemi
- Mari E. K. Niemi
- Mari E. K. Niemi
- Mari E. K. Niemi
- Mari E. K. Niemi
- Mari Kaunisto
- Maria Antonietta Mazzei
- Maria Antonietta Mencarelli
- Maria Bandini
- Maria J. Arranz
- Maria Lorubbio
- Maria Palmieri
- Maria Teresa La Rovere
- Marie Coignet
- Marie Thys
- Mario Capasso
- Mario Tumbarello
- Mario Umberto Mondelli
- Marissa Zyndorf.
- Mark Daly
- Mark J. Caulfield
- Markus Perola
- Marta Corridi
- Marta Garcıa-Clemente
- Marta GuindoMartinez
- Marta L. DeDiego
- Martin D. Tobin
- Marwa H. Elnagdy
- Mary Ann Belli
- Mary K. Balaconis
- Marylyn D. Ritchie
- Masahiro Kanai
- Masahiro Kanai
- Masahiro Kanai
- Massimiliano Fabbiani
- Massimo Carella
- Massimo Di Pietro
- Massimo Girardis
- Massimo Mangino
- Massimo Vaghi
- Mathieu Quinodoz
- Matsui Hiroko
- Matteo Bassetti
- Matteo Della Monica
- Matteo Siano
- Matthew C. Gass
- Matthew Solomonson
- Matthew Solomonson
- Matti Pirinen
- Mattia Cordioli
- Mattia Cordioli
- Mattia Cordioli
- Mattia Cordioli
- Mattia Cordioli
- Mattia Cordioli
- Mattia Cordioli
- Mattia Cordioli
- Maureen Oliveira
- Maurizio Bussotti
- Maurizio Sanarico
- Maurizio Sanguinetti
- May Alrashed
- Meike Bartels
- Melania Degli Antoni
- Menachem Zlatopolsky
- Meriem Bouab
- Miao Zhang
- Michael Gaddis
- Michael Hultstroš m
- Michael N. Cantor
- Michael Peruggia
- Michael Preuss
- Michaeš l ChasseŽ
- Michel (M. G. ) Nivard
- Michel Georges
- Michel Moutschen
- Michelle Daya
- Mihael H. Polymeropoulos
- Miklos Lipcsey
- Milos Pavlovic
- Mirella Bruttini
- Miriam Lucia Carriero
- Miriana DâAlessandro
- Mirjam Lista
- Mohamed A. F. Hegazy
- Mohamed R. El-shanshory
- Mohamed S. Abd Elghafar
- Mohamed S. Torky
- Mohammad S. Fawzy
- Mohammed A. Eid
- Mona Sawaji
- Moneera Alswailm
- Monica Poscente
- Monnat Pongpanich
- Monpat Chamnanphon
- Morteza Saeedi
- Nadia Harerimana
- Nardin Rezk Branka Vulesevic
- Natalia Blay
- Natalia Cullell
- Nathalie Brassard
- Nathan Berkowitz
- Nathan Cheng
- Nattiya Hirankarn
- Navya Shilpa Josyula
- Nguyen Jennifer P
- Nicholas Rafaels
- Nick Shrine
- Nicola Picchiotti
- Nicolas Arning
- Nicolas Tardif
- Nicole Soranzo
- Nikolas Baya
- Nils Koelling
- Noam D. Beckmann
- Noemie Boillat
- Noemie Suh
- Nofar Kimchi
- Noor Mamlouk
- Nora Aljawini
- Nouf AlDhawi
- Nour Albesher
- Noura S. Abul-Husn
- Olav Rooyackers
- Olivier Malaise
- Olumide Adeleye
- Opass Putchareon
- Oreste De Vivo
- P-PredictUs SeroCOVID
- Pajaree Chariyavilaskul
- Paloma de la Cal-Sabater
- Paloma Menendez-Valladares
- Pamela Raggi
- Paola Bergomi
- Paola Petrocelli
- Paolo Cameli
- Paolo Di Domenico
- Paolo Piacentini
- Part Peterson
- Pascale Huynen
- Patrick Deelen
- Patrick Turley
- Patrizia Zucchi
- Pattama Torvorapanit
- Paul H. Lee
- Paul M. Ridker
- Paul Naaber
- Paul OâReilly
- Paul R. H. J. Timmers
- Pauline Lanting
- Per Magnus
- Pere Soler
- Petty E. Lauren
- Phil Tsao
- Philippe LeÂŽ onard
- Pier Giorgio Scotton
- Pierpaolo Parravicini
- Pierre Lepage
- Pierre-Yves Bochud
- Pietro Pinoli
- Pimpayao Sodsai
- Pintip Suchartlikitwong
- Prabhu Arumugam
- Qin Qin Huang
- Rachel G. Liao
- Rafael de Cid
- Raffaele Bruno
- Raffaele Scala
- Raghavendran Partha
- Rahul Gupta
- Raili Allos
- Rana Hasanato
- Rasoul Aliannejad
- Ravaglia Sabrina
- Raymond K. Walters
- Reedik Magi
- Renato Polimanti
- Renzo Scaggiante
- Riccardo Colombo
- Richard C. Trembath
- Richard H. Scott
- Richard J. Packer
- Rita Perna
- Roaa T. Halawani
- Robert C. Free
- Robert C. Green
- Robert Frithiof
- Robert P. Sebra
- Robert Warmerdam
- Roberta Russo
- Roger Colobran
- Ron Do
- Rosangela Artuso
- Rossella Tita
- Rui Li
- Ruth J. F. Loos
- Ryan C. Thompson
- Sabine Claassen
- Sabino Scolletta
- Sabrina Ravaglia
- Saeideh Ahmadi
- Salam Massadeh
- Saleh Alqahtani
- Sam Bryant
- Sam Bryant
- Sam Choi
- Sameer Chavan
- Sameera AlJohani
- Sami Koskelainen
- Samira Azarzar
- Samuli Ripatti
- Sandra P. Smieszek
- Sandro Mancarella
- Sandro Panese
- Sanni Ruotsalainen
- Sara Alotaibi
- Sara Amitrano
- Sara Pigazzini
- Sara Pigazzini
- Sara Pigazzini
- Sara Pigazzini
- Sarah Alkwai
- Sarah Finer
- Sarah G. Earle
- Sauro Luchi
- Saverio Giuseppe Parisi
- Scott T. Weiss
- Sebastian Garcıa Madrona
- Semira Gonseth Nussle
- Serafina Valente
- Serena Ludovisi
- Serghei Mangul
- Sergio Daga
- Seyed Behrooz Mohseni Moghaddam
- Shang-Kuan Lin
- Shannon McCurdy
- Shawn N. Murphy
- Shawneequa Callier
- Shea J. Andrews
- Shea J. Andrews
- Shea J. Andrews
- Shefali S. Verma
- Shona M. Kerr
- Silvia Baroni
- Silvia Cappelli
- Silvia Rojo
- Simona Dei
- Simona Marcantonio
- Simona Sarzi-Braga
- Simone Furini
- Slayton J. Underwood
- Sophie Venturelli
- Souad Rahmouni
- Spencer Knight
- Stefania Mantovani
- Stefano Baratti
- Stefano Busani
- Stefano Ceri
- Stefano Rusconi
- Stephanie Bibert
- Stephen J. Wicks
- Steven Ascolillo
- SteÂŽ phanie Gofflot
- Stuart C. Sealfon
- Susan Walker
- Susanna Croci
- Susanna Guerrini
- Tala Abdullah
- Tamer A. Elhadidy
- Tess Levy
- Thanyawee Puthanakit
- Thitima B. Suttichet
- Tim D. Spector
- Tiziana Bachetti
- Tom Fowler
- Tomas Segura
- Tomislav Maricic
- Tomoko Nakanishi
- Tomoko Nakanishi
- Tonu Esko
- Tooraj Mirshahi
- Tormod Rogne
- Triin Laisk
- Tullio Trotta
- Valentina Anemoli
- Vasilios Polymeropoulos
- Veronica Rico
- Veronica Robles
- VeÂŽronique Erard
- Victor Moreno
- Vincent Mooser
- Vincenzo Forgetta
- Vincenzo Forgetta
- Voraphoj Nilaratanakul
- Vorasuk Shotelersuk
- Walaa A. Felemban
- Walaa M. El-Lawaty
- Walid T. Khafaga
- Wanna Chetruengchai
- Watsamon Jantarabenjakul
- Wei Zhou
- Wei Zhou
- Wenhan Lu
- Werner Albrich
- Xavier Farre
- Xiao Chang
- Xiao Chang
- Xiaoqing Xue
- Xueyang Wang
- Yan V. Sun
- Yaseen M. Arabi
- Yasmine Belhaj
- Yasser M. El-Sherbiny
- Yen-Chen Anne Feng
- Yuk-Lam Ho
- Yuki Bradford
- Yunsung Lee
- Yuval Itan
- Yves Beguin
- Zaman Afrasiabi
- Zeinab Naderpour
- Zhu Wanying
- Ziab Z. Alahmadey
- Ăyvind Helgeland
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between individuals is partly due to
genetic factors. Here, we identify 4 genomic loci with suggestive associations for SARS-CoV-2 susceptibility
and 19 for COVID-19 disease severity. Four of these 23 loci likely have an ethnicity-specific component.
Genome-wide association study (GWAS) signals in 11 loci colocalize with expression quantitative trait loci
(eQTLs) associated with the expression of 20 genes in 62 tissues/cell types (range: 1:43 tissues/gene),
including lung, brain, heart, muscle, and skin as well as the digestive system and immune system. We perform
genetic fine mapping to compute 99% credible SNP sets, which identify 10 GWAS loci that have eight or fewer
SNPs in the credible set, including three loci with one single likely causal SNP. Our study suggests that the
diverse symptoms and disease severity of COVID-19 observed between individuals is associated with variants across the genome, affecting gene expression levels in a wide variety of tissue types
World Congress Integrative Medicine & Health 2017: Part one
- Author
- Aarva Paulina
- Abanades Sergio
- Abbadey Miznah
- Abbadey Miznah
- Adam Daniela
- Adams Jon
- Adams Jon
- Adams Jon
- Agdal Rita
- Ahnoumy Shafekah
- Alamoudi Omer
- AlBedah Abdullah
- Alorizi Seyed M E
- AlrĂŠk Terje
- Amarell Catharina
- Amarell Catherina
- Amarell Catherina
- Amarell Catherina
- Amini Fatemeh
- Ammendola Aldo
- Amri Hakima
- Amunni Gianni
- An Ruopeng
- Andermo Susanne
- Anderson Belinda
- Anheyer Dennis
- Anheyer Dennis
- Anheyer Dennis
- Anheyer Melanie
- Anheyer Melanie
- Annese Christine
- Arau Annemarie
- Arimitsu Junsuke
- Arman Maria
- Arnon Zahi
- Arnon Zahi
- Arye Eran
- Arye Eran
- Atarzadeh Fatemeh
- Attias Samuel
- Aval Shapour B
- Avidan Benjamin
- Avshalomov David
- Azari Masoumeh A
- Azizi Hamideh
- Azizi Hamideh
- Azizi Hoda
- Azizi Hoda
- Baars Erik
- Baccetti Sonia
- Baccetti Sonia
- Bai Chen
- Balneaves Lynda
- Bandelin Lena
- Barth JĂŒrgen
- Barth JĂŒrgen
- Bashtian Maryam H
- Baumann Klaus
- Beccia Ariel
- Bedregal Paula
- Beissner Florian
- Beissner Florian
- Beljanski Sylvie
- Belland Laura
- Benson Herbert
- Bentner Martina
- Berberat Pascal O
- Berger Bettina
- Berger Bettina
- Berger Bettina
- Berger Bettina
- Beyer Jörg
- Bhasin Manoj
- Biffi Sauro
- Binstock Maxwell
- Binting Sylvia
- Binting Sylvia
- Binting Sylvia
- Binting Sylvia
- Bishop Felicity
- Bishop Felicity
- Bishop Felicity
- Blanco Mar
- Blonde Clara
- Blonde Clara
- Bocci Chiara
- Boers Inge
- Boers Inge
- Bogani Patrizia
- Bonin D
- Bonucci Massimo
- Boon Heather
- Boon Heather
- Boon Heather
- Boothroyd Clare
- Boulanger Karen
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- Bradbury Katherine
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- Brand Bernhard
- Breen Jenny
- Breitkreuz Thomas
- Briggs Josephine P
- Brinkhaus Benno
- Brinkhaus Benno
- Brinkhaus Benno
- Brinkhaus Benno
- Brinkhaus Benno
- Brinkhaus Benno
- Brodzky Marc
- Bronfort Gert
- Brooks Audrey
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- Bruin Anja
- Bruset Stig
- Bu Xiangwei
- Bucuras Petru
- Bugarcic Andrea
- Buleu Florina
- Burnstock Geoffrey
- Busch Martine
- ButtĂł Ludovica
- BĂŒssing Arndt
- BĂŒssing Arndt
- BĂŒssing Arndt
- BĂŒssing Arndt
- BĂŒssing Arndt
- Caldwell Christine
- Canella Claudia
- Cao Hui-juan
- Capler Rielle
- Carnes Dawn
- Carnes Dawn
- Castillo Noelia
- Chang Jessica
- Chang Mayling
- Chang Yinhui
- Chapman Michael
- Chen Bingzhong
- Cheon Chunhoo
- Cheshire Anna
- Ching Jessica Y L
- Cho Hyun J
- Cho Yumin
- Choi Da
- Choi Soo J
- Chouping Han
- Christodorescu Ruxandra
- Chuang Elisabeth
- Chung Vincent C H
- Coakley Amanda
- Cooley Kieran
- Cooper Cyrus
- Cotton Sian
- Cotton Sian
- Courneene Brendan
- Cramer Holger
- Cramer Holger
- Cramer Holger
- Cramer Holger
- Cramer Holger
- Cramer Holger
- Cree Margit
- Cysarz Dirk
- Dagnelie Pieter
- Daher Michel
- Daneshfard Babak
- Daneshfard Babak
- Daneshfard Babak
- Demerdash Abdulrahman
- Denninger John
- Derk Gwendolyn
- Dicen Demijon
- Diez Camino
- Dieze Helene
- Diezel Helene
- Diezel Helene
- Dimitrov Borislav
- Dimitrov Borislav
- Dobos Gustav
- Dobos Gustav
- Dobos Gustav
- Dobos Gustav
- Dobos Gustav
- Dobos Gustav
- Dong Fei
- Dong Fei
- Dongen Martien
- Dragan Simona
- DrÀger Kilian
- Dubois Julie
- Dunlap Corina
- Dusek Jeffrey
- Eckert Marion
- Eckert Marion
- Eckert Marion
- Eckert Marion
- EdelhÀuser Friedrich
- EdelhÀuser Friedrich
- Eisenberg David
- Elyakim Rami
- Empoliti Joanne
- Esmaily Habibollah
- Esmaily Habibollah
- Esmaily Habibollah
- Esmel Neus
- Espinosa Stéphane
- Estiri Nazanin
- Evans Roni
- Evans Roni
- Evans Roni
- Fahey Paul
- Falkenberg Torkel
- Falkenberg Torkel
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- Fan Xueyi
- Fang T.
- Fani Renato
- Fattahi Mohammad R
- Fawkes Carol
- Fawkes Carol
- Fei Yu-Tong
- Fei Yu-Tong
- Feng Xue
- Ferreri Rosaria
- Firenzuoli Fabio
- Firenzuoli Fabio
- Firenzuoli Fabio
- Fischer Isabell
- Fisher Peter
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- Flanagan Jane
- Flower Andrew
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- Flower Andrew
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- Fogerite Susan
- Foote Trevor R
- Foster Jo
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- Frick Eckhard
- Fuente Francisca
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- FĂžnnebĂž Vinjar
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- Gafer Nahla
- Gallo Eugenia
- Gamus Dorit
- Gao Zishan
- Goldblatt Elisabeth
- Gomez Olga
- Grabenhenrich Linus
- Gramminger Harsha
- Graz Bertrand
- Gruber Harald
- Gruber Harald
- GrĂ€Ăel Elmar
- GrĂŒnther Ralph-Achim
- Gu Xiaohong
- Gu Xiaohong
- Gu Xiaohong
- Guckenberger Matthias
- Guendling Nadine
- Guendling Peter W
- Guerrero Fanny
- Guffi Marta
- Gupta Hedwig H
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- Haas Mitch
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- Haller Dirk
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- Hamme Gesa-Meyer
- Han Dongwoon
- Han Dongwoon
- Haramati Aviad
- Haramati Aviad
- Haramati Aviad
- Haramati Aviad
- Haramati Aviad
- Hassanzadeh Malihe
- He Luzhu
- He Y.
- Heinrich Michael
- Heinrich Michael
- Helin Kaija
- Henriksson Roger
- Herrera Maria
- Heusser Peter
- Hilgard Dörte
- Ho Robin S T
- Hoff Evelyn
- Hohmann Christoph D
- Holmes Michelle
- Holtermann Christoph
- Horin Shomron
- Horneber Markus
- Hoseini Leila
- Hu Xiao-Yang
- Hu Xiao-Yang
- Huang Ching W
- Hueber Carly
- Hughes John
- Hughes John
- Hummelsberger Josef
- Hwang Ula
- Högl Manuel
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- Ijaz Nadine
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- Im Hyea B
- Irnich Dominik
- Ivaldi Giovanni B
- Jacobs Christoph
- Jaladat Amir M
- Jan Sae B
- Jang Bo H
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- Jenewein Josef
- Jian Pei
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- Jin Li
- Jocham Alexandra
- Johnson Neil
- Jong Mats
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- Jong Miek
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- Jung Sonny
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- JĂ€ger Sven F
- Kaimiklotis John
- Kao Lan
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- Kebudi Rejin
- Kemper Kathi
- Kerckhoff Annette
- Kern Alexandra
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- Khadem Nayereh
- Khadivzadeh Talat
- Khalil Mohamed
- Kienle Gunver S
- Kim Eun S
- Kim Ha Y
- Kim Jihye
- Kim Keun H
- Kim Rana
- Klafke Nadja
- Klein Hedda
- Kligler Ben
- Kligler Ben
- Kligler Ben
- Kligler Benjamin
- Klocke Carina
- Klose Petra
- Ko Seong G
- Ko Youme
- Koch Sabine
- Kopylov Uri
- Kortum Ria
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- Koshak Emad
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- Kraft Karin
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- Lahat Adi
- Lai Lily Y
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- Langhorst Jost
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- Leach Matthew
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- Leininger Brent
- Leininger Brent
- Leung Brenda
- Lewith George
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- Lewith George
- Lewith George
- Li Jin-gen
- Liang Fanrong
- Liang Ning
- Liang Ning
- Libermann Towia
- Lill JR
- Linde Klaus
- Linde Klaus
- Linka Esther
- Little Paul
- Liu Bin
- Liu Jian-Ping
- Liu Jian-Ping
- Liu Jian-ping
- Liu Jian-ping
- Liu Tiegang
- Liu Tiegang
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- Mahler Cornelia
- Mao Jun J
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- Matthes Harald
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- Meaglia Ilaria
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- Meng Fengxian
- Mengoni Alessio
- Miceli Elisangela
- Michalsen Andreas
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- Michalsen Andres
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- Motoo Yoshiharu
- Mudd Lanay M
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- Munk Niki
- Murakozy Henriette
- Musial Frauke
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- Naafs Marianne
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- Nimri Omar
- Nimrouzi Majid
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- Nordberg Johanna H
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- Ogawa Keiko
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- Ortiz Miriam
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- Passi Alvaro
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- Paul Friedemann
- Pendergrass Anna
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- Petrescu Marius
- Philpotts Lisa
- Ping Liu
- Pohlmann Urs
- Ponstein Anne
- Popovici Roxana
- Porcu Patrizia
- Preibisch Christine
- PuigmartĂ Carolina
- Pushparaj Peter
- Qutub Majdy
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- Rostock Matthias
- Rotter Gabriele
- Rotter Gabriele
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- Schiff Elad
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- SchlÀppi Marc
- Schnabel Katharina
- SchneeweiĂ Andreas
- Schneider Antonius
- Schröder Sven
- Schröer Beate
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- Schulz Craig
- Schumann Dania
- Schwartze Sophia
- Schwarz Silke
- Schömitz Meike
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- Simon Patrick
- Six Claudia
- Smith Caroline
- Sorsa Minna
- Stange Rainer
- Stange Rainer
- Stankewitz Josephin
- Steckhan Nico
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- Steel Amie
- Steel Amie
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- Stefano Mariella
- Stefano Mariella
- Steinberg Lois
- Stoichescu Gheorghe
- Stoll Sarah
- Stoltenberg Anna
- Strobl Judit
- Stuart Beth
- Stuart Beth
- Stub Trine
- Stub Trine
- Stupp Roger
- Stöckigt Barbara
- Stör Wolfram
- Suhr Ralf
- Sundberg Tobias
- Sundberg Tobias
- Szecsenyi Joachim
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- Taghanaki Hamidreza
- Takeda Wendy
- Tauschel Diethard
- Tauschel Diethard
- Tavassoli Fatemeh
- Teut Michael
- Teut Michael
- Theorell Töres
- Thijs Carel
- Tissing Wim
- Tjaden Bram
- Trapp Barbara
- Tremel Nadine
- Tröger Wilfried
- Tucek Gerhard
- Uhlmann Lorenz
- Ullmann Alexander
- Vahle Maik
- Vega Miguel
- Villanueva Irene
- Vlieger Arine
- Vliet Marja
- Vliet Marja
- VoiĂ Petra
- Voller Fabio
- von Hagens Cornelia
- Vuolanto Pia
- Wali Siraj
- Wan Yuxiang
- Wan Yuxiang
- Wan Yuxiang
- Wang Dali
- Wang J.
- Wang Li-qiong
- Wang Xuan
- Wang Ying
- Ward Lesley
- Wardle Jon
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- Wardle Jon
- Wartner Eva
- Wasson Rachel
- Watanabe Kenji
- Wayne Peter
- Weber Wendy
- Weidenhammer Wolfgang
- Wen Grace Y G
- Wenzel Claudia
- White Shelley
- Wie Li
- Wieland Lisa S
- Wieland Lisa S
- Wiesener Solveig
- Wietmarschen Herman
- Willcox Merlin
- Willcox Merlin
- Willich Stefan N
- Witt Clauda
- Witt Claudia
- Witt Claudia
- Witt Claudia
- Witt Claudia
- Witt Claudia M
- Witt Claudia M
- Wode Kathrin
- Wong Hoi L C
- Wong Lisa M
- Wong Wendy
- Wu Darong
- Wu Justin
- Wu Justin
- Wu Justin C Y
- Wu Liqun
- Wu Ruo-Han
- Wu Ruo-Han
- Wu Xin Y
- Wullinger Michael
- WĂŒst Ana P
- Xu Jingnan
- Yan Liyi
- Yan Liyi
- Yan Xianzhong
- Yang Yufei
- Yardley Lucy
- Yardley Lucy
- Yardley Lucy
- Yeh Gloria
- ying Yang
- Yu He
- Yu He
- Yu He
- Yu Shuguang
- Zabihi Reza
- Zabihi Reza
- Zakeresfahani Arash
- Zalpour Christoff
- Zarshenas Mohammad M
- Zhang X.
- Zhang Yuqing
- Zhang Zhengju
- Zhen Jianhua
- Zheng Zian
- Zheng Zian
- Zheng Zian
- Zieger Anja
- Zillgen Hannah
- Zoderer Iris
- Zwickey Heather
- Ăzbe Dominik
- ĂztĂŒrk Ali Ă
- ĂztĂŒrk Gizemnur
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
A first update on mapping the human genetic architecture of COVID-19
- Author
- Abd Elghafar Mohamed S.
- Abdel-Aziz Mahmoud
- Abdollahi Hamed
- Abdullah Tala
- Abecasis Goncalo R.
- Abedalthagafi Malak
- Abul-Husn Noura S.
- Acquilini Donatella
- Adams Emma L.
- Adamsara Alireza
- Adeleye Olumide
- Adra Darin
- Afilalo Jonathan
- Afilalo Marc
- Afrasiabi Zaman
- AgĂŒero Daiana
- Ahmadi Saeideh
- Akhtar Shaheen
- Aksentijevich Alexandra
- Al-Afghani Hani
- Al-Awdah Laila
- Alaamery Manal
- Alahmadey Ziab Z.
- Alaverdian Diana
- Alavere Helene
- Albader Anoud
- Albaiceta Guillermo M.
- Albakri Jehad K.
- AlBardis Hadeel
- Albeladi Maha
- Albesher Nour
- Albrich W. C.
- Albrich Werner
- AlDhawi Nouf
- Aleagha Afshar Etemadi
- Alghamdi Bader
- Alghamdi Jahad
- Ali Altaf
- Aliannejad Rasoul
- Aljawini Nora
- AlJohani Sameera
- Alkwai Sarah
- Allos Raili
- AlMalik Abdulaziz
- Almalki Faisal
- Almohammed Iman
- Almutairi Mansour
- Alotaibi Sara
- Alowayn Albandary M.
- Alqahtani Saleh
- Alqubaishi Fatimah
- Alrashed May
- Alshareef Abdulraheem
- Alsolm Ebtehal
- Alswailm Moneera
- AlZahrani Deema
- Amirsavadkouhi Ali
- Amitrano Sara
- Andolfo Immacolata
- Andretta Francesca
- Andreucci Elena
- Andrews Shea J.
- Anedda Federico
- Anemoli Valentina
- Angelantonio Emanuele Di
- Annis Aubrey
- Antinori Andrea
- Antoni Melania Degli
- Anwar Mohammad
- Arabi Yaseen M.
- Arciero Elena
- Armstrong Jacob
- Arning Nicolas
- Arranz Maria J.
- Arribas Elisa
- Artuso Rosangela
- Arumugam Prabhu
- Ascolillo Steven
- Ashraf Samina
- Atkinson Elizabeth G.
- Aucella Filippo
- Auld Daniel
- AZARZAR Samira
- Bachetti Tiziana
- Baillie J. Kenneth
- Balaconis Mary K.
- Baldassarri Margherita
- Ball Catherine A.
- Baltzell Asher Haug
- Band Gavin
- Bandini Maria
- Baraka Dona
- Baras Aris
- Baratti Stefano
- Barbieri Chiara
- Barda B.
- Bargagli Elena
- Barhoush Eman
- Barnes Kathleen C.
- Baroni Silvia
- Bartels Meike
- Bassetti Matteo
- Batini Chiara
- Baya Nikolas
- Beck Andrew
- Beckmann Noam D.
- Bedini Josep L.
- Bee Catherine E.
- Beguin Yves
- Belbin Gillian M.
- Belhaj Yasmine
- Beligni Giada
- Belisle Alexandre
- Belli Mary Ann
- Below Jennifer
- Benetti Elisa
- Bennett David
- Bergantini Laura
- Bergomi Paola
- Berkowitz Nathan
- Bernardo David
- Biagio Antonio Di
- Bianchi Francesco
- Bibert Stéphanie
- Bibert Stéphanie
- Biesecker Les
- Biscarini Filippo
- Blay Natalia
- Bochud M.
- Bochud P. Y.
- Bochud P. Y.
- Bochud Pierre-Yves
- Bochud Pierre-Yves
- Boezen Marike
- Boillat Noémie
- Boillat-Blanco N.
- BottĂ Giordano
- Bouab Meriem
- Boughton Andrew P.
- Bouras K.
- Bradford Yuki
- Brahier T.
- Brassard Nathalie
- Breen Gerome
- Brenner Bluma
- Britvan Bari
- Brumpton Ben M.
- Bruno Raffaele
- Bruttini Mirella
- Bryant Sam
- Bryant Sam
- Buring Julie E.
- Busani Stefano
- Bussotti Maurizio
- Butler-Laporte Guillaume
- Butterworth Adam S.
- Buxbaum Joseph D.
- Caldarelli Gian Piero
- Callier Shawneequa
- Cameli Paolo
- Campbell Archie
- Campbell Archie
- Canaccini Anna
- Cantarini Luca
- Cantor Michael N.
- Capasso Mario
- Capitani Katia
- Cappelli Silvia
- Carella Massimo
- Carey Dave J.
- Carreras Anna
- Carriero Miriam Lucia
- Castaño-Vinyals Gemma
- Castelli Francesco
- Castori Marco
- Catena Emanuele
- Caulfield Mark J.
- Ceri Stefano
- Cerny A.
- Chamnanphon Monpat
- Chan Georgia
- Chang Xiao
- Chang Xiao
- Chariyavilaskul Pajaree
- Charney Alexander W.
- Chasman Daniel I.
- Chassot J.
- Chassé Michaël
- Chaudhary Kumardeep
- Chavan Sameer
- Chen Hung-Hsin
- Cheng Nathan
- Chetruengchai Wanna
- Chittoor Geetha
- Cho Judy H.
- Cho Kelly
- Choi Sam
- Chowdhury Maharun
- Chung Raymond
- Churchhouse Claire
- Chwialkowska Karolina
- Claassen Sabine
- Claringbould Annique
- Clerc O.
- Coignet Marie
- Coiro Gabriella
- Colligan Grainne
- Collins Brett L.
- ColobrĂĄn Roger
- Colombo Riccardo
- Conen A.
- Conticini Edoardo
- Cordioli Mattia
- Cordioli Mattia
- Corridi Marta
- Cortés Beatriz
- Cossarizza Andrea
- Coto Eliecer
- Coviello Domenico A.
- Croci Leonardo
- Croci Susanna
- Crook Derrick W.
- Crooks Kristy
- Crotti Lia
- Cullell Natalia
- Curtis Charles J.
- Cusick Caroline
- CĂĄrcel-MĂĄrquez Jara
- Daga Sergio
- Dalmau David
- Daly Mark
- Daly Mark J.
- Danesh John
- Darcis Gilles
- Davis Lea
- Daya Michelle
- de Cid Rafael
- de Felipe Mimbrera Alicia
- de geus Eco E. J. C.
- de la Cal-Sabater Paloma
- DeDiego Marta L.
- Deelen Patrick
- Dei Simona
- Deloukas Panos
- Desanctis Elena
- Desgranges F.
- di Bartolomeo C.
- Dietl Beatriz
- Do Ron
- Dobaño Carlota
- Doddato Gabriella
- Domenico Paolo Di
- Domingo Carlos
- DomĂnguez-Mayoral Anna
- Donati Alice
- Donner Kati
- Durand Madeleine
- Durham Ceri
- DâAcremont V.
- DâAlessandro Miriana
- DâArminio Monforte Antonella
- DâMellow Kenton
- Earle Sarah G.
- Egger T.
- Eid Mohammed A.
- El-Jawhari Jehan J.
- El-Lawaty Walaa M.
- El-shanshory Mohamed R.
- El-Sherbiny Yasser M.
- Elhadidy Tamer A.
- Elnagdy Marwa H.
- Eltoukhy Madonna M.
- Emiliozzi Arianna
- Emma Duncan
- Erard VĂ©ronique
- Erard VĂ©ronique
- Esko TÔnu
- Estoppey Younes S.
- Fabbiani Massimiliano
- Falcone Marco
- Fallerini Chiara
- Farré Xavier
- Fava Francesca
- Fawns-Ritchie Chloe
- Fawns-Ritchie Chloe
- fawzy Mohammad S.
- Felemban Walaa A.
- Feng Yen-Chen Anne
- Feri Marco
- Fernandez-Cadenas Israel
- Ferreira Manuel A. R.
- Ferri Claudio
- Filipovic M.
- Filippidis P.
- Finer Sarah
- Finer Sarah
- Finucane Hilary
- Fiorentino Giuseppe
- Fiz-LĂłpez Aida
- Forgetta Vincenzo
- Foucras S.
- Fowler Tom
- Franchi Federico
- Francisci Daniela
- Franco Giulianini
- Franke Lude
- Frediani Bruno
- Free Robert C.
- Frenckell Christian Von
- Friolet R.
- Frippiat Frédéric
- Frischknecht M.
- Frithiof Robert
- Frullanti Elisa
- Furini Simone
- Gabbi Chiara
- Gabrieli Arianna
- Gaddis Michael
- GalvĂĄn-FemenĂa IvĂĄn
- Ganna Andrea
- Garcia-Aymerich Judith
- GarcĂa-Clemente Marta
- GarcĂa-Madrona Sebastian
- Gass Matthew C.
- Gatti Francesca
- Gaziano J. Michael
- Georges Michel
- Gettler Kyle
- Ghosh Biswarup
- Giannattasio Ferdinando
- Gignoux Christopher R.
- Giliberti Annarita
- Giorli Alessia
- Giot Jean-Baptiste
- Girardis Massimo
- Girshick Ahna
- Glessner Joseph R.
- Glessner Joseph T.
- Gofflot Stéphanie
- Goldstein Jacqueline I.
- Gomez Juan
- Gonseth Nussle S.
- GonzĂĄlez-Villa Esther
- Gori Marco
- Grassi Davide
- Green Robert C.
- Griffiths Chris
- Griffiths Christopher J.
- Grip Jonathan
- Guarnaccia Alessandra
- Guerrini Susanna
- Guidelli Luca
- Guillet A.
- Guindo-Martinez Marta
- Guiot Julien
- Guntz Julien
- Gupta Rahul
- Guturu Harendra
- Guyat-Jacques C.
- Guyatt Anna L.
- Guzman Charlotte
- Guéry B.
- Haefliger D.
- Hakonarson Hakon
- Hakonarson Hakon
- Halawani Roaa T.
- Harerimana Nadia
- Harris Jennifer R.
- Harthi Fawz Al
- Hasanato Rana
- Hayward Caroline
- Hayward Caroline
- Hegazy Mohamed A. F.
- Helgeland Ăyvind
- Henry Danielle
- Hensen Kati
- Hiester Liam L.
- Hirankarn Nattiya
- Ho Yuk-Lam
- Hoggart Clive
- Hollox Edward J.
- Hong Eurie L.
- Horowitz Julie E.
- Hosseini Abdolmajid
- Hottenga Jouke Jan
- Huang Qin Qin
- Huang Qin Qin
- Huckins Laura M.
- Huffman Jennifer E.
- Hultström Michael
- Hunt Karen A.
- Hunt Karen A.
- Hurles Matt
- Hussain Shapna
- Huynen Pascale
- Hveem Kristian
- HĂŒgli O.
- Iglesias Lara Lloret
- Ikram M. Arfan
- Iolascon Achille
- Islam Kamrul
- Itan Yuval
- Jacques Jessica
- Jantarabenjakul Watsamon
- Jaquet M.
- Jiménez-Xarrié Elena
- John Catherine
- Jordan Daniel M.
- Josyula Navya Shilpa
- Jung Junghyun
- Justice Anne E.
- Kahlert C. R.
- Kallaste Anne
- Kamdar Dhryata
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- Kanai Masahiro
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- Karczewski Konrad J.
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- Magnus Per
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- Marcantonio Simona
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- Marciano Carmen
- Mari Francesca
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- MartĂ-FĂ bregas Joan
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- Mercader Josep
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- Merla Giuseppe
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- Meuris Christelle
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- Miah Shefa
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- Petitjean Louis
- Petrocelli Paola
- Phokaew Chureerat
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- Squeo Gabriella Maria
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- Vecchia Marco
- Veerapen Kumar
- Venn Laura D.
- Venturelli Sophie
- Vergori Alessandra
- Verma Anurag
- Verma Shefali S.
- Verzuri Agnese
- Viala B.
- Villalonga Joan Montaner
- Vincenti Antonella
- Viollet R. Merlet
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- Voide Cathy
- Voide Cathy
- Vollenweider P.
- Vollenweider P.
- von Hohenstaufen Kathrin Aprile
- von Mering C.
- Vonk Judith. M.
- Vulesevic Branka
- Wain Louise V.
- Walker Susan
- Walters Raymond K.
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- Wang Xueyang
- Wanying Zhu
- Warmerdam Robert
- Weiss Scott T.
- Wicks Stephen J.
- Willer Cristen
- Williams Alexander T.
- Wilson Daniel J.
- Wilson James F.
- Wolford Brooke
- Wolford Brooke
- Wolford Brooke
- Woolley Ann E.
- Wozniak H.
- Wright John
- Wright John
- Wyllie David H.
- Xue Xiaoqing
- Yadav Ashish
- Yassen Amr M.
- Zanella Isabella
- Zeberg Hugo
- Zguro Kristina
- Zhang Miao
- Zhao Jing Hua
- Zhou Wei
- Zhou Wei
- Zlatopolsky Menachem
- zu Bentrup F. Meyer
- Zucchi Patrizia
- Zyndorf Marissa
- Zöllner Sebastian
- Ă svold BjĂžrn Olav
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
peer reviewe
The effectiveness of a cooling vest in post-exercise recovery in sprint kayaking elite male athletes
- Author
- Publication venue
- MRE Press
- Publication date
- 01/08/2022
- Field of study
Background: Cooling vests are popular and widely used in many sports. There are several studies about their efficacy but there is not much evidence about their impact on the recovery of kayak sprint male athletes. Methods: Ten elite male sprint kayakers completed an exercise protocol on a kayak ergometer on two separate days. They were randomized to wear a cold vest during a 15 min active rest on one of these days. Following the pre designed protocol, all sessions were performed in a climate chamber with controlled temperature and humidity conditions. At both moments, the blood lactate concentration was determined, as well as urine temperature. Skin temperature in the latissimus dorsi muscle area was assessed several times along the protocol, using infrared thermography. Borgâs rating of perceived exertion (RPE Scale) was applied to the protocol after each exercise bout and the perceived recovery scale was applied before the last moment of the protocol (500 m test). Results: The subjective perception of recovery was significantly higher during the cooling vest condition (p < 0.01). There were no significant differences on performance in the 500 m maximal test when comparing both days. On the other hand, after the active recovery with cold vest, the skin temperature (p < 0.01), urine temperature (p < 0.05) and blood lactate concentration were all significantly lower (p < 0.05). Discussion: Results revealed that the cooling vest is a suitable instrument to induce a decrease in skin and core temperature while paddling and also to reduce more quickly the blood lactate concentration. The vest should be tested under on-water conditions in order to consider other factors such as wind and solar radiation. Conclusions: Wearing a cooling vest during active rest after a training session or a competition seems to improve the recovery of male kayakers
Principles of 3D chromosome folding and evolutionary genome reshuffling in mammals
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Studying the similarities and differences in genomic interactions between species provides fertile grounds for determining the evolutionary dynamics underpinning genome function and speciation. Here, we describe the principles of 3D genome folding in vertebrates and show how lineage-specific patterns of genome reshuffling can result in different chromatin configurations. We (1) identified different patterns of chromosome folding in across vertebrate species (centromere clustering versus chromosomal territories); (2) reconstructed ancestral marsupial and afrotherian genomes analyzing whole-genome sequences of species representative of the major therian phylogroups; (3) detected lineage-specific chromosome rearrangements; and (4) identified the dynamics of the structural properties of genome reshuffling through therian evolution. We present evidence of chromatin configurational changes that result from ancestral inversions and fusions/fissions. We catalog the close interplay between chromatin higher-order organization and therian genome evolution and introduce an interpretative hypothesis that explains how chromatin folding influences evolutionary patterns of genome reshuffling.This work was supported by the Ministry of Economy, Industry and Competitiveness (CGL2017-83802-P to A.R.-H.) and the Spanish Ministry of Science and Innovation (PID2020-112557GB-I00 to A.R.-H. and PID2020-115696RB-I00 to M.A.M.-R.). Research funding to P.D.W. (Australian Research Council grants DP180100931, DP210103512, and DP220101429) and T.J.R. (South African National Research Foundation) are gratefully acknowledged. C.V. and L.A.-G. were supported by FPI predoctoral fellowships from the Ministry of Economy and Competitiveness (BES-2015-072924 and PRE-2018-083257). L.M.-G. was supported by an FPU predoctoral fellowship from the Spanish Ministry of Science, Innovation and University (FPU18/03867). C.A.-S. was supported by a GTA fellowship from the University of Kent
Apolipoprotein B, Residual Cardiovascular Risk After Acute Coronary Syndrome, and Effects of Alirocumab.
- Author
- Abbas Jalal
- Abbate Antonio
- Abdallah mouhamad
- Abdullakutty Jabir
- Abdullkutty Jabir
- Abhyanakar Atul D
- Aboyans Victor
- Abrantes José Antonio M
- Abu-Fadel Mazen
- Accini Mendoza Jose L
- Acevedo Monica
- Adamkova Vera
- Adamo Antony
- Adhyapak Srilakshmi
- Agarwal Himanshu
- Aggarwal Rahul
- Aggarwal Rajesh K
- Agnetti Veronique
- Aguirre Arnoldo
- Ahmed Hinan
- Ahremark Ulf
- Ahuad Guerrero Rodolfo A
- Aidar Ayoub José Carlos
- Airaksinen Juhani
- Aitken Denise
- Akatova Evgenia
- Akhter Faiq
- Ako Junya
- Akright Laura
- Akyea-Djamson Ayim
- Al Joundi Tammam
- Al-Windy Nadea YY
- Alan David
- Albert Seals
- Alcocer Gamba Marco Antonio
- Alexander John H.
- Alexander Karen
- Alexandru Tom M
- Alings Marco
- Alings Marco
- Alonso Martin Joaquin J
- Alonso Alvaro
- Alsweiler Caroline
- Alvarisqueta Andrés F
- Alves De Lima Alberto E
- Amarasekera Stanley
- Amarasena Naomali
- Amidon Thomas
- Amir Offer
- Amlani Mohamadali
- Amosova Ekaterina
- Amuchastegui Marcos
- Anchante Hernandez Henry A
- Andersen Dorthe
- Andersen Kjell
- Andersen Rolf
- Anderson Jay
- Anderson Jay
- Ando Kenji
- Annam Sharath
- Anscombe Russell
- Apostolovic Svetlana R.
- Appel Karl-Friedrich
- Arambula Rafael Suarez
- Arandjelovic Aleksandra
- Araneda Guillermo
- Arango Benecke Juan L
- Arbel Yaron
- Arif Imran
- Armaganijan Luciana
- Aroca Carlos Cotes
- Aroney Constantine
- Arstall Margaret A
- Asanin Milika R.
- Assi Nizar
- Aswegen Dina Van
- Atar Shaul
- Athyros Vasilios
- Auguadro Carla
- Ayaz Mohammad
- Aylward Philip E
- Aylward Philip E
- Aylward Philip E
- Aylward Philip E
- Azizad Masoud M
- BabiÄ Zdravko
- Badreddine Emmy
- Bagai Akshay
- Bagriy Andriy
- Bahit Maria Cecilia
- Bai Feng
- Baldari Duccio
- Balinovac Jovan
- Ball Eric
- Ball Eric
- Bang Lia E
- Banuru Sridhar
- Barakovic Fahir
- Baranov Evgeny
- Baranova Elena
- Barbarash Olga L
- Barbato Emanuele
- Barna Olga M
- Barone-Rochette Gilles
- Barr Craig
- Barraud Pauline
- Barrera Silva Sandra I
- Barrucco Robert
- Bartels Gerard L
- Basart Dirk
- Bashir Riyaz
- Bata Iqbal
- Batushkin Valeriy
- Bayat Junaid
- Bayram Llamas Edmundo Alfredo
- Bayron Carlos
- Beauloye Christophe
- Bednarski Janusz
- Behrens Steffen
- Bejuit Raphael
- Bekkouche Mhamed
- Belhassane Abdelkader
- Beltran Pascale
- Benbernou Fadela
- Benedicto Amparo
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- Benov Haralambi O
- Berdan Lisa
- Berger Rudolf
- Berglund Stefan
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- Berman Brett
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- Berti Sergio
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- Bhagwat Ajit
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- Bhatt Deepak L.
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- Binde Ronald
- Birchem Jessica
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- Blumberg Eduardo DS
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- Bodanese Luiz C
- Bojovski Stojko
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- Bourgeois Ronald
- Brabham David
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- Chaudhary Sanjeev
- Chavez Ayala Carlos A
- Cheema Muhammad
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- Chen Jiyan
- Chen Yundai
- Cheng Shi-Chi
- Cheng Xiaoshu
- Chengyue Zhu
- Chiang Chern-En
- Chiang Chern-En
- Chizhov Petr
- Chopda Manoj
- Chopra Vijay K
- Chotnoparatpat Paiboon
- Christenson Stuart
- Christopher Daniels
- Chu Alan
- Chua Terrance
- Chumakova Galina
- Chumburidze Vakhtang
- Chumburidze Vakhtang
- Cianciarulo Joseph
- Claeys Marc
- Claxton Edmund
- Clemmensen Peter
- Clerc JĂ©rĂŽme
- Cleveland David
- Clifford Piers
- Clifton Shaun
- Cobler Joanne
- Coching Raul Martin
- Codutti Oscar R
- Cohen Steven
- Colhoun Helen M.
- Collins Nicholas
- Colombo Hugo R
- Colquhoun David
- Coman Ioan
- Commerford Patrick J
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- Constantine Godwin
- Constantinescu Mircea CA
- Convens Carl
- Cools Frank
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- Cortada Jordi Bruguera
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- Coste Pierre
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- Coufal Zdenek
- Coulange Anthony
- Coverdale Steven GM
- Cristian Gabriel
- Cruz FernĂĄndez Jose M
- Cuccia Claudio
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- Daboul Nizar
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- Dandillaya Ramprasad
- Daniels Christopher
- Das Srihari
- Davidovic Goran
- Davidsen Flemming
- Davidson Laura
- Davies Richard
- Davis William
- De Berrazueta Fernåndez José R
- De Cesare Nicoletta B
- De La Tassa CĂ©sar MorĂs
- De Leon MarĂa Guerrero
- De Mora Martin Manuel
- De Salazar Dora I Molina
- de Santos Mayler ON
- de Silva H. Asita
- de Souza Juliana A
- de V Basson Matthys M
- Delarche Nicolas
- Delle-Karth Georg
- Deloatch Shalonda
- Demirtas Mustafa
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- Denham Douglas
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- DeVore Adam D.
- Diamantis Steve
- Diaz Ariel
- Diaz Rafael
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- Dickey Sheila
- Dilic Mirza
- Dilic Mirza
- Dimkovic Sinisa
- Dimov Bojidar I
- Dincic Dragan V.
- Ding Chunhua
- Dion Danielle
- Do Rose
- Dodds III George
- Dodic Slobodan
- Dohad Suhail
- Doi Yasuji
- Dombrowski Keith
- Domokos Szilvia
- Doncovska Snezana
- Dong Shaohong
- Dong Yugang
- Dorobantu Maria
- Dorobantu Maria
- Dorsel Thomas
- Dotani Imran
- Doty Daniel
- Dran Ricardo D
- Drexel Heinz
- Drexel Heinz
- Drouet Elodie
- Drzewiecka Anna
- du Toit Theron Hendrik
- Dubois-Gache Helene
- Ducas John
- Ducrocq Grégory
- Duda Norberto
- Dujardin Karl
- Dukat Andrej
- Dulak Elzbieta
- Dumitrescu Silviu
- Dupuis Robert
- Durak-Nalbantic Azra
- Durand Velasquez Julio R
- Duronto Ernesto A
- Dzupina Andrej
- Dzyak Georgiy
- DĂaz FernĂĄndez Jose Francisco
- DâUrso Michael
- Eagerton Donald
- Eapen Zubin
- East Cara
- Eaton Charles
- Ebrahim Iftikhar O
- Edelberg Jay M.
- Edward Kemala
- Egorova Liudmila
- Egydio Flavia
- Ehud Chorin
- Eisenberg Steven
- Ekanayaka Ruvan
- El Shahawy Mahfouz
- El- Ahdab Fadi
- Elias Mazen
- Elias Nizar
- Eliaschewitz Freddy G
- Elliott John
- Endsley Patricia
- Eppinger Arleen
- Erenrich Norman
- Erglis Andrejs
- Ersanli Murat
- Escudier Juan M
- Espinoza Andrey
- Etienne Alexis
- Fadlallah Hussein
- Faes Dirk
- Faggiano Pompilio
- Fairlamb James
- Faluközy József
- Fan Zhongcai
- Fang Chih-Yuan
- Fang Weiyi
- Farhat Naim
- Farrar Michael
- Faustino Douglas
- Fausto Ovando Sergio R
- Fazekas FrantiĆĄek
- Fazlibegovic Emir
- Feenema-Aardema Margriet
- Feenema-Aradema Margriet
- Feitosa Gilson S
- Fell David
- Feng Yi
- fenton Sarah
- Fernandez Ruiz Ricardo L
- Fernandez Mauricio
- Fernando Kaputella
- Fernando Nimali
- Ferrari Emile
- Ferratini Maurizio
- Ferrolino Arthur
- Filardi Pasquale Perrone
- Filho Pedro Pimentel
- Fillat Angel R. Cequier
- Fischer Stuart
- Fishberg Robert
- Fisher Daniel
- Fisher Nicholas
- Fisher Raewyn
- Florenzano Fernando
- Flores Enrique
- Fong Peter
- Fontecave Sylvie
- Forgosh Les
- Foster Malcolm
- Foster Robert
- Fournie-Lloret Dominique
- Francis Adi
- Franek Edward
- Fras Zlatko
- Fras Zlatko
- French William J
- Frey Bernhard
- Friedman Dennis
- Friedman Keith
- Frost Lars
- Fu Guosheng
- Fuchs Shmuel
- Fuentealba Victorino
- Fujii Kenshi
- Fujimoto Kazuteru
- Fujimoto Kazuteru
- Fujinaga Hiroyuki
- Fulop Peter
- Fulwani Mahesh C
- Furukawa Yutaka
- Gabor Kiss Robert
- Gache Cecile
- Galski Thomas
- Galvani Marcello
- Gamil Dawood
- Gapon Liudmila
- Garbelotto Raffaella
- Garcia Brasca Daniela F
- Garcia Duran Ruben O
- Garcia Lozada Henry J
- Garcia-Dorado David
- GarcĂa LledĂł JosĂ© Alberto
- Gardner Geraldine
- Garrahy Paul J
- Garrido Marcelo
- Garza RuĂz JosĂ© Angel
- Gavish Dov
- Ge Junbo
- Gelormini Joseph
- Gerber Jaime
- Gerber Robert
- Ghitis Arnold
- Ghlonti Ramaz
- Gibson Paul
- Gielen Stephan
- Giesler Gregory
- Gil-Extremera Blas
- Gilbert John M
- Gillespie Eve
- Gilmore Richard
- Gimple Lawrence
- Giordano Jorge A
- Giorgeto Flavio E
- Gislason Gunnar
- Giuliano Maria E
- Gniot Jacek
- Gobillot Caroline
- Goch Aleksander
- Goloborodko Borys
- Gomez Vilamajo Oscar A
- Gonsorcik Jozef
- Gonzalez-Juanatey Carlos
- Gonzalez-Juanatey Jose R
- GonzĂĄlez DĂaz Belinda
- GonzĂĄlez Salas Luis Gerardo
- Goodman Shaun G.
- Goodman Shaun G.
- Goodman Shaun G.
- Goodman Shaun G.
- Goraya Tauqir
- Gordeev Ivan
- Gordienko Alexander
- Gorny Jerzy
- Goronja Boris
- Gospodinov Maryana
- Gosselin Gilbert
- Gosselink Antonius TM
- Gotcheva Nina N
- Gotcheva Nina N
- Gouet Valerie
- Govinda Ravishankar A
- Goyal Naresh K
- Gremmler Uwe
- Grewal Jasprakash Singh
- Griffith Liddy
- Griffiths Huw
- Gring Christian
- Groenemeijer Bjorn E
- Groutars Reginald GEJ
- Grunberg Lena
- Guardigli Gabriele
- Guha Santanu
- Guillou Severine
- Gullestad Lars
- Guneri Sema
- Guneri Sema
- Guo Ying
- Gupta Jugal
- Gurevich Victor
- Guy Douglas
- Guzman Pablo N
- GĂ€mperli Oliver
- Haddad Tariq
- Hagström Emil
- Hagström Emil
- Hagström Emil
- Hagström Emil
- Hahalis Georgios
- Halabi Majdi
- Hald Flemming
- Haldis Thomas
- Hall Jason
- Halle Benjamin
- Halvorsen Sigrun
- Halvorsen Sigrun
- Hameed Adnan
- Haniffa Ruvaiz
- Hanotin Corinne
- Hansen Ole
- Haraguchi Takuya
- Harding Scott
- Harkut Pankaj
- Harrington Robert A.
- Harrington Robert A.
- Harris Barry
- Harris Bill
- Harrison Robert W.
- Hart Hamish
- Hasan Mian
- Hasin Yonathan
- Hata Yoshiki
- Hattler Brack
- Hatzitolios Apostolos
- Healy Jan
- Heath Megan
- Hedman Anu
- Heidenreich Lothar
- Heinc Petr
- Heitzer Thomas
- Hemetsberger Rayyan
- Henderson David
- Henkin Yaakov
- Henry John
- Hepditch Anita
- Herath Jagath I
- Hermans Kurt
- Hermans Walter RM
- Hernandez Zuniga Jose D
- Herrman Johannes PR
- Hersbach Ferry MRJ
- Herzog William
- Hess Connie Ng
- Hidalgo Urbano Rafael Jesus
- Higashikata Toshinori
- Higuera Juan Diego
- Hii Chris LS
- Hirayama Atsushi
- Hirooka Keiji
- Hlatky Mark A.
- Hoag Gordon
- Hodes Zachary
- Hoffer Etienne
- Hoffman David
- Hominal Miguel Angel
- Hong Taekjong
- Hoogslag Pieter AM
- Hoppe Uta
- Horak David
- Horowitz John
- Horvath IvĂĄn
- Horwitz Phillip
- Hove Jens D
- Hrabar Adrian D
- Hranai Marian
- Hsiang Lin Wei
- Hsieh I-Chang
- Hsieh Ming-Jer
- Huang Lan
- Huang ShiâAn
- Huang Tsuei-Yuan
- Huang Weijian
- Huber Kurt
- Huidobro Laura
- Huikuri Heikki
- Hunter John
- Hurtig Ulf
- Hussein Osamah
- Huynh Thao
- Hwang Juey- Jen
- Ilic Stevan
- Ilieva- Pandeva Katya A
- Ilya Masterov
- Ince Carlos
- Iqbal Syed MR
- Irimpen Anand
- Islam Othman
- Islam Shahidul
- Istratoaie Octavian
- Ito Kashima
- Ivanov Igor G
- Ivanova Raya
- Ivanovic Nikola
- Iyengar Shamanna S
- Iñiguez Andres
- Jacoby Douglas
- Jafar Zubair
- Jaffrani Naseem
- Jain Diwakar
- Jaiwal Gayatri
- Jakimov Tamara
- Janik Matthew
- Janosik Denise
- Jaramillo Nicolas
- Javierre Carine
- Jayawardena Jayanthimala
- Jensen Steen Agergaard
- Jeong Myung Ho
- Jeppesen JĂžrgen
- Jeserich Michael
- Jiang Weihong
- Jimenez Francisco Fuentes
- Jintapakorn Woravut
- Johansen Peter
- Johansen Peter Betton
- Jonas Michael
- Jones William Schuyler
- Jong Geert T
- Jordan Joseph Dedrick
- Jortveit Jarle
- Joshi Abhijeet B
- Joshi Parag
- Jovin Ion
- Jujjuru Srimannarayana
- Jukema J. Wouter
- Jukema J. Wouter
- Jukema Johan
- Jure Horacio O
- Jurgaitiene Ruta
- Jurgenson Tiina
- Kadr Honer
- Kaewsuwanna Pinij
- Kahali Dhiman
- Kaiser Sergio
- Kalashetti Suhas
- Kalil Renato
- Kamensky Gabriel
- Kamiya Haruo
- Kandasamy Balachandran
- Kanorsky Sergey
- Kapin Tibor
- Kaplan Refik
- Kapp Ilse E
- Karadzic Ana
- Karakas Mahir
- Karalis Ioannis
- Karlsberg Ronald
- Karpenko Oleksandr
- Karpenko Yuriy
- Karpov Yuri
- Karpov Yuri
- Karpov Yuriy
- Kartalis Athanasios
- Kasim Sazzli
- Kathryn Rohr
- Katona AndrĂĄs
- Katsuda Yousuke
- Katz Amos
- Kaucak Vladimir
- Kavaliauskiene Roma
- Kawakami Anelise
- Kawasaki Tomohiro
- Ke Yuannan
- Keating Friederike
- Kedev Sasko
- Kedev Sasko
- Keen William
- Kehasukcharoen Wirash
- Kelsey Sheryl F.
- Kerkar Prafulla
- Khabeishvili George
- Khaira Ajit S
- Khaisheva Larisa
- Khan Abul
- Khan Aziz
- Khasanov Niiaz
- Khera Amit
- Khintibidze Irakli
- Khlevchuk Tatiana
- Khurana Sandeep
- Kibarskis Aleksandras
- Kichukov Kostadin N
- Killat Holger
- Kim Chongjin
- Kim Hack-Lyoung
- Kim Hae Young
- Kim Hyo Soo
- Kim Hyo-Soo
- Kim Moo Hyun
- Kim Sang-Hyun
- Kim Sang-Hyun
- Kim Youngkwon
- Kimmelstiel Carey
- Kimura Kazuo
- Kimura Takeshi
- Kimura Takeshi
- King Marilyn
- Kinzfogl III George
- Kirma Cevat
- Kishi Koichi
- Kiss Robert Gabor
- Kjovkaroski Aleksandar
- Klancke Kim
- Klantsa Andriy
- Klausen Ib C
- Kline Geoffrey
- Klutstein Marc
- Knickelbine Thomas
- Knowles Joshua W.
- Knutson Thomas
- Koba Shinji
- Kobalava Zhanna
- Kobayashi John
- Koike Akihiro
- Koldas Lale
- Kolls Bradley J.
- Kondo Nicholas I
- Kong David F.
- Kopytsya Mykola
- Koren Michael
- Kormann Adrian
- Kornder Jan
- Kornowski Ran
- Korol Marek
- Kosinski Edward
- Kosmachova Elena
- Kostarska-Srokosz Edyta
- Kostis John
- Kotha Purushotham
- Kouz Simon
- Kovalskyi Ihor
- Kozuma Ken
- Kralova Katarina
- Krasowski Wlodzimierz
- Krawczyk Justine
- Krichmar Perry
- Kristensen Kjeld S
- Kristjan Arved
- Kubilius Raimondas
- Kuchar Jiri
- Kuhlman Peter
- KuliÄ Mehmed
- Kultursay Hakan
- Kumar Yerra Shiv
- Kumar Anil
- Kumar Priya
- Kumar Vinay
- Kumbla Mukund
- Kumkumian Greg
- Kuo Jen-Yuan
- Kurian John
- Kushnir Mykola
- Kutniy Oles
- Kuvin Jeffrey
- Kyiak Yulian
- Labeirie Julien
- Labroo Ajay
- Lai Christopher
- Lai Wen-Ter
- Lambert Charles
- Lamoureux Maud
- Landeo Javier Heredia
- Landmesser Ulf
- Landmesser Ulf
- Landzberg Joel
- Larry John
- Larsen John
- Laucevicius Aleksandras
- Laufs Ulrich
- Laxson David
- Lazov Petar V
- Leaes Paulo E
- Leclercq Florence
- Lecorps Guillaume
- Lecorps Guillaume
- Lee Kaeng
- Lee Kwan
- LefĂšvre Thierry
- Leggewie Stefan
- Lehman Sam J
- Leimbach Wayne
- Lekakis John
- Leo Alessandro De
- Leonard Parilak
- Leonardi Sergio
- Leone Attilio
- Lepage Serge
- Lepor Norman
- Leshchuk Oleh
- Lester F. Martin
- Leung Raymond
- Levite Howard
- Levy Terry
- Li Huanming
- Li Jianping
- Li Tianchang
- Li Xiang
- Li Xiaodong
- Li Ying
- Lianopoulos Emmanouil
- Liberman Alberto
- Liberopoulos Evangelos
- Liberopoulos Evangelos
- Liberopoulos Evangelos
- Libov Igor
- Licciardello Giovanni
- Lieber Ira
- Liem Anho AH
- Liew Houng B
- Lillis Linda
- Lin Jinxiu
- Lin Wenhua
- Lin Xuefeng
- Lindsey Jason
- Linhart Ales
- Link Chad
- Lip Gregory YH
- Lipko Jan Andrzej
- Lishner Michael
- Liu Ming-En
- Liu Shaowen
- Liu Xuebo
- Llamas EsperĂłn Guillermo Antonio
- Llerena Navarro Nassip C
- Llois Susana
- Loizeau Virginie
- Lomakin Nikita V
- Lomholdt Jens D
- Lominadze Zaza
- Lopes Renato D.
- Lopes Renato D.
- Lopes Renato D.
- Lopes Renato D.
- Lopez Rodrigo Botero
- Lorenzato Christelle
- Lorenzatti Alberto J
- Lotan Chaim
- Lottering Hanlie
- Lotun Kapildeo
- Loussararian Arthur
- Love Michael
- LovriÄ BenÄiÄ Martina
- Lozance Nensi
- Lu Qinghua
- Lubinski Andrzej
- Luca Giuseppe De
- Luciardi Hector L
- Lui Henry
- Lukenda Josip
- Luna Botia Diana C
- Luo Zhurong
- Lupkovics Geza
- Lupovitch Steven
- Luquez Hugo A
- Lutchmedial Sohrab
- Luyten Anne
- Lyamina Nadezhda
- Lysek Roman
- LĂłpez-Jaramillo Patricio
- MacDonald Paul
- Macdonell Alexander
- Mach Francois
- Machado Leandro
- Machecourt Jacques
- Machova Vilma
- Mackinnon Ignacio J
- Madrigal Jaime Carranza
- Mahaffey Kenneth W.
- Mahaffey Kenneth W.
- Mahajan Ajaykumar
- Mahal Sharan
- Maia Lilia Nigro
- MajercĂĄk Ivan
- Makoali Makotoko Ellen
- Malhotra Vinay
- Malis Mihaela
- Malozzi Christopher
- Malynovsky Yaroslav
- Manakshe Gajendra V
- Manenti Euler Roberto F Fernandes
- Mano Toshiaki
- Manolis Athanassios
- Mansourati Jacques
- Manvelian Garen
- Manzur Jatin Fernando G
- Marais H. John
- Marco Valgimigli
- Marcus Jill
- Markov Dimitar T
- Markov Valentin
- Marmor Alon
- Maron David J.
- MartĂnez SĂĄnchez Carlos Rodolfo
- Marusincova Ivana
- Marx Nikolaus
- Marx Nikolaus
- Marx Nikolaus
- Marx Roger
- MarĂn Francisco
- Maskon Oteh
- Massey Clara
- Masutani Motomaru
- Matei Adrian V
- Mathews Robin
- Mathur Rishabh
- Matiga Generoso
- Matthews Alexander
- Matuska Jiri
- May Ole
- May Wade
- Mayurathan Gnanamoorthy
- Mazur Juraj
- McClanahan Mark A.
- Mcclure Sam
- Mcgarvey Joseph
- McGinniss Jennifer
- Mcgough Martin
- Mclaurin Brent
- Medrano Allende Juan C
- Mehta Rajendra H.
- Mehta Shamir
- Mejic-Krstulovic Stanka
- Meloni Chiara
- Mendis Sepalika
- Mendonça Carlos
- Mentz Robert J.
- Merkely Bela
- Mesquita Bastos Jose
- Metra Marco
- Metwally Lamia
- Michalaros Yorghos L
- Michaud Nicolas
- Michishita Ichiro
- Micko Karol
- Midzic Zlatko
- Miklaszewicz Beata
- Mileta Dean
- Militaru Constantin
- MiliÄiÄ Davor
- Mincheva Valentina M
- Minescu Bogdan
- Mintale Iveta
- Misonis Nerijus
- Mittal Suneet
- Moccetti Tiziano
- Mody Freny
- Mohart Ann Elizabeth
- Molchanova Olga
- Mollov Mihail N
- Monier Myriam
- Monraats Pascalle
- Montalescot Gilles
- Montaña Oscar R
- Montecinos Humberto
- Monteiro Minguel R
- Monteiro Pedro
- Montenegro Valdovinos Pablo Carlos
- Moodley Rajendran
- Morais Joao
- Morais Joao
- Morales Dante D.
- Morales Ulises
- Moran Joseph
- Moreira Humberto Graner
- Morel Olivier
- Moriarty Andrew
- Moriarty Katie
- Moriarty Patrick M.
- Moriarty Patrick M.
- Morino Yoshihiro
- Morisset Anne
- Morrello Christine
- Moryusef AngĂšle
- Mosseri Morris
- Mostovoy Yuriy
- Motovska Zuzana
- Moura Jorge Jose C
- Mourgues Maxime
- Mourtzinis Georgios
- Mrabti Asmaa
- Mthombeni Bicky
- Mudawi Telal
- Muenzel Thomas
- Mulkay Angel
- Munk Peter S
- Munusamy Vengatesh
- Murillo Fernando Civeira
- Murin Jan
- Murin Jan
- Murphy Judith
- Murphy Sherrill
- Muslibegovic Adis
- Musumeci Giuseppe
- Muthusamy Rangasamy
- Mutlu Bulent
- Mynhardt Joseph H
- Myshanych Halyna
- MĂ€rtsin Kaja
- MĂŒller Christian
- MĂŒller Christian
- MĂŒller GĂĄbor
- MĂŒller-Wieland Dirk
- Nacoud Ackar Alfredo
- Nager Paul
- Nagy Lajos
- Nahhas Ahed
- Nahuelpan Leonardo
- Nakao Koichi
- Nani Sebastian
- Naplava Robert
- Natour Mohammed
- Negron Miguel Sandra A
- Nelson William
- Neto Jose A Marin
- Neuenschwander Fernando
- Neustel Mark
- Nicol Peter
- Nicolau Jose C
- Nielsen Peter Kaiser
- Nielsen Tonny
- Nieminen Markku S
- Nieminen Markku S
- Nigro Frank
- Nijmeijer Remco
- Nikolaev Konstantin
- Nikolov Fedya P
- Nikolsky Eugenia
- Ninio Daniel
- Nishibe Akira
- Nishibe Akira
- Nociar Jan
- Nogareda Gustavo
- Norkiene Sigute
- Normand Mickael
- Novaretto Leonardo P
- Novo Salvatore
- Novoa Federico
- Novotny Vojtech
- Nuding Sebastian
- NygÄrd Ottar
- NĂșñez Fragoso Juan Carlos
- Ofer Havakuk
- Offers Elmar
- Okan Betim
- Olexa Peter
- Olivares Claudia
- Olivari Zoran
- Oliveira Janaina
- Oliver Richard
- Olsson Anders G.
- Omran Heyder
- Ong Tiong Kiam
- Ono Yujiro
- Oomen Antonius
- Oomman Abraham
- Oqueli Flores Romulo E
- Orcajo Norberto Alonso
- Orlikova Olga
- Osokina Natalya
- Ossei-Gerning Nicholas
- Ostadal Petr
- Ostadal Petr
- Ourliac Anne
- OâDonnell Philip J.
- Paganelli Franck
- Pagava Zurab
- Palimkar Priya
- Palka Juraj
- Palmer Bruce
- Palvarini Michela
- Panchal Vipul
- Pancholy Samir
- Pandey Amritanshu
- Pandurangi Ulhas
- Parada Jeffrey Castellanos
- Parepa Irinel R
- Park Hyeun (Tom)
- Parkhomenko Alexander
- Parkhomenko Alexander
- Parthenakis Frangkiskos
- Pasquini John
- Patange Dr. Aparna
- Patel Chetan B.
- Paterlini Gustavo A
- Patil Chandrakant
- Patil Sachin N
- Patki Nitin
- Patocchi Cristian A
- Patsilinakos Sotiris
- Pawar Sudhir
- Pawlowicz Lidia
- Payeras Antonio Coca
- Pearce Stephen
- Pederson Robert
- Pella Daniel
- Pellan Valerie
- Pellegrin Annamaria De
- Peng Daoquan
- Penny William
- Pepine Carl
- Pereira Edward
- Pereira Helder H
- Pereira Sabrina Bernardez
- Perez Ignacio Plaza
- Perez Luis
- Pericas Laia Matas
- Peris Vicente BodĂ
- Perkins Lynn
- Perlmutter Neal
- Perthuis Aurelie
- PerĆĄiÄ Viktor
- Pesant Yves
- Petranov Stanislav L
- Petrulioniene Zaneta
- PeÄin Ivan
- Piatti Piermarco
- Picault Patrick
- Picone Mark
- Piepiorka Marek
- Pillay Thayabran
- Pincetti Cristian
- PintariÄ Hrvoje
- Piovaccari Giancarlo
- Pirenne Bruno
- Piyayotai Dilok
- Podoleanu Cristian GC
- Podpera Ivo
- Poh Kian-Keong
- Pojskic Belma
- Poklukar Janez
- Pollock Stewart
- Ponce George
- Ponnamperuma Chandrike
- Pontaga Natalija
- Pope Theodore
- Pordy Robert
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- Portales Javier Fernandez
- Porwal Sanjay
- Pothineni Ramesh B
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- Probst Vincent
- Prokhorov Alexander
- PrvuloviÄ Äeiti
- Puccioni Enrico
- Puri Sanjeev
- Purow Joshua
- Puymirat Etienne
- PĂ©rez RĂos JesĂșs Antonio
- Qu Baiming
- Quintero Ossa Alvaro M.
- Quintero Kirby
- Racca Vittorio
- Raczak Grzegorz
- Radin Michael
- Radovanovic Slavica
- Raev Dimitar H
- Raffel Owen
- Raffo Carlos A
- Raghuraman Bagirath
- Rahma Gohar
- Rahman Aref
- Rahul Patil
- Raisinghani Ajit
- Rajapaksha Ajantha
- Ramin Ebrahimi
- Ramos LĂłpez Gabriel Arturo
- Ramos LĂłpez Gabriel Arturo
- Ramos Walter Mogrovejo
- Ranadive Nandkishore
- Ranasinghe Gotabhaya
- Ranjith Naresh
- Rao Sunder
- Rasmanis Gundars
- Rasoul Saman
- Ratky Caroline
- Rauch-Kröhnert Ursula
- Raungaard Bent
- Ray Kausik K.
- Ray Michael
- Recena Javier Balaguer
- Rech Rafael
- Reddy Proddutur Naveen
- Regella Reddy
- Reiner Zeljko
- Reis Gilmar
- Reis Helder JL
- Rensing Bernard JWM
- Repincay JĂ©rĂŽme
- Reshetko Olga
- Reshotko Dmytro
- Reuter Helmuth
- Reynolds Timothy
- Rha Seungwoon
- Riaz Garda
- Richard Kerensky
- Rider James
- Rieker Werner
- Rincon Pablo Loma-Osorio
- Rishko Mykola
- Ristic Arsen D.
- Ristic Arsen D.
- Ritt Luiz Eduardo F
- Roberts-Thomson Philip
- Robinson Simon
- Rodes-Cabau Josep
- Rodriguez Chavez VĂctor E
- Rodriguez De Leon Edgar R
- Rodriguez Javier Botas
- Roe Matthew T.
- Roe Matthew T.
- Roe Matthew T.
- Roe Matthew T.
- Rogelio Gregorio
- Rogers James F
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- Rokyta Richard
- Roldan Concha Yudy M
- Romeo Stefano
- Rondel Christelle
- Ronner Eelko
- Roosen John
- Rorick Tyrus
- Rosas Enrique LĂłpez
- Rose Gregory
- Rosenberg Michael
- Rosenschein Uri
- Rosenson Robert
- Rossi Joseph
- Rossi Paulo RF
- Rossi Peter
- Rosu Doina
- Rouleau Jean-Lucien
- Rozeman Phillip
- Rozenman Yoseph
- Rubenstein Howard
- Rudenko Anatolii
- Rudenko Leonid
- Saaiman Jan A
- Saathe Shireesh
- Saavedra Silvia S
- Sabatino Kenneth
- Sabbah Eric
- Sachin Patil
- Sader Mark
- Sakagami Satoru
- Sakalyte Gintare
- Salmón Guillermo FanghÀnel
- Salomone Oscar
- Salvioni Alessandro
- Saminski Krzysztof
- Sanabria Perez Enrique S
- Sandhu Manjinder
- Sansanayudh Nakarin
- Saporito Wladmir
- Sarkar David
- Sarvan Mahomed
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- Sassone Sonia A
- Sastravaha Krisada
- Sathe Shireesh
- Sato Katsuhiko
- Savard Daniel
- Sawhney Jitendra
- Scalise Filippo
- Scemama Michel
- Scemama Michel
- Schaeufele Tim
- Schellenberg Detlev
- Schiavi Lilia B
- Schiele Francois
- Schifferdecker Branislav
- Schmalfuss Carsten
- Schmedtje John F
- Schmidberg Jorge M
- Schmidt Ekkehard
- Schmitt Susanne
- Schuchard Timothy
- Schwartz Gregory G.
- Schwartz Gregory G.
- Schwartz Michael
- Schwartz Steven
- Scott Douglas
- Sebastian Peter J
- Seferovic Petar
- Seixo Filipe
- Selecky Juraj
- Senaratne Manohara
- Senaratne Vajira
- Senni Michelle
- Serrano Antolin Jose Maria
- Sethi Sumeet
- Shaburishvili Tamaz
- Shah Anil V
- Shah Bimal R.
- Shah Vipul
- Shalaev Sergey
- Sharma Mukesh
- Sharman David
- Shaw James
- Shaw Michelle
- Shchekotov Vladimir
- Shechter Michael
- Shehova-Yankova Nina S
- Sheldon William
- Sheller Jennifer
- Sherwood Matthew W.
- Shetty Sanjay
- Shi Xubo
- Shimatani Yuji
- Shimizu Masatoshi
- Shinde Rituparna
- Shinke Toshiro
- Shou Xiling
- Shoukfeh Mohammad
- Shustov Sergey
- Shvarts Yury
- Sijbrands Eric J.G.
- Sik Park Hun
- Silva Pedro
- Silva Ricardo P
- Silveira Jose A
- Silver Kevin
- Simaitis Audrius
- Sime Iveta
- Simic Dragan
- Simon Tabassome
- Simonis Gregor
- Simoons Maarten L.
- Singal Dinesh
- Singh Narendra
- Singsaas Erlend gyllensten
- Sinha Dhurjati
- Sinnaeve Peter
- Sinnaeve Peter
- Sinnaeve Peter
- Sionis Dimitrios
- Sirisena Thilak
- Siu David CW
- Skonieczny Grzegorz
- Skorski Marcin
- Skoumas Ioannis
- Slapikas Rimvydas
- Smik Rudolf
- Smith Lucile
- Smith Simon
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- Soonfuang Wasant
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- Soran Handrean
- Soroka Eugene
- Sotnikova Tatiana
- Sotomayor Herazo Aristides
- Sotty Marc
- Sousa Luciano
- Souza Weimar KSB
- Soward Allan
- Sparby Jon Arne
- Speirs Shawn
- Spinar Jindrich
- Sporn Daniel
- Spriggs Douglas
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- Vogel Robert
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- Vora Kishor
- Vora Kishor
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- Vrolix Mathias CM
- Vulic Dusko
- Vuurmans Tycho
- Våzquez de Prada José Antonio
- VĂĄzquez Eduardo Salcido
- Vöhringer Hans Friedrich
- Völler Heinz
- Wada Atsuyuki
- Waider Winfried
- Waisman Gabriel D
- Waites Jonathon H
- Wali Andreas
- Walichiewicz Piotr Maria
- Waltenberger Johannes
- Waltman Jonathan
- Wan Mohamed Wan Mohd Izani
- Wang Jianzhong
- Wang JianâAn
- Wang Jingfeng
- Wattanakit Keattiyoat
- Wei Meng
- Weidinger Franz
- Weil Joachim
- Weintraub Howard
- Weiss Robert
- WeiĂbrodt Matthias
- Welka Stephen
- Welker James
- Welker James
- Wells Terry
- Wells Terry
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- Werner Nikos
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- Wilkins Gerard
- Wilkinson Peter
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- Wiseman Alan
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- Wlodarczak Adrian
- Wojewoda Pawel
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- Wong Yuk- Ki
- Wongpraparut Nattawut
- Worner Diz Fernando
- Wozniak Julianna
- Wright Scott
- Wu Chun
- Xavier Denis
- Xenakis Mark
- Xiang Meixiang
- Xu Biao
- Xu Dingli
- Xu Xiping
- Xu Yizhou
- Yagensky Andriy
- Yakushin Sergey
- Yan Bryan PY
- Yang Eric
- Yang Xiangjun
- Yang Xinchun
- Yao Zhuhua
- Yazdani Shahram
- Yañez Mario
- Yee Ong Hean
- Yin Wei-Hsian
- Yong Huo
- Yoon Jung Han
- Younis Liwa
- Yu Yihua
- Yuan Zuyi
- Yusoff Khalid
- Yusoff Khalid
- Zahger Doron
- Zahr Firas
- Zaidman Cesar J
- Zainea Mark
- Zaman Azfar
- Zamorano Jose Luis
- Zapata Gerardo
- Zea Nunez Carlos A
- Zeiher Andreas M.
- Zeiher Andreas M.
- Zhang Ruiyan
- Zhang Wenwu
- Zhang Xuelian
- Zhang Zheng
- Zhao Shuiping
- Zhao Xingsheng
- Zheleznyy Volodymyr
- Zheng Yang
- Zheng Zeqi
- Zhong Yi
- Zhou Yujie
- Zhu Hong
- Zhu Jianhua
- Zirlik Andreas
- Zizka Jiri
- Zobouyan Isabelle
- Zong Wenxia
- Zrazhevsky Konstantin
- Zukermann Robert
- Zurakowski Aleksander
- Zvi Vered
- Zwart Peter
- Zweiker Robert
- Ădes IstvĂĄn
- Ć ikiÄ Jozica
- Ć tambuk Kresimir
- Ć uligoj NataĆĄa ÄerniÄ
- Ćœuran Ivan
- Publication venue
- American Heart Association
- Publication date
- 30/08/2022
- Field of study
Background: Apolipoprotein B (apoB) provides an integrated measure of atherogenic risk. Whether apoB levels and apoB lowering hold incremental predictive information on residual risk after acute coronary syndrome beyond that provided by low-density lipoprotein cholesterol is uncertain. Methods: The ODYSSEY OUTCOMES trial (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) compared the proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab with placebo in 18â924 patients with recent acute coronary syndrome and elevated atherogenic lipoproteins despite optimized statin therapy. Primary outcome was major adverse cardiovascular events (MACE; coronary heart disease death, nonfatal myocardial infarction, fatal/nonfatal ischemic stroke, hospitalization for unstable angina). Associations between baseline apoB or apoB at 4 months and MACE were assessed in adjusted Cox proportional hazards and propensity scoreâmatched models. Results: Median follow-up was 2.8 years. In proportional hazards analysis in the placebo group, MACE incidence increased across increasing baseline apoB strata (3.2 [95% CI, 2.9â3.6], 4.0 [95% CI, 3.6â4.5], and 5.5 [95% CI, 5.0â6.1] events per 100 patient-years in strata 35â<50, and â€35 mg/dL, respectively). Compared with propensity scoreâmatched patients from the placebo group, treatment hazard ratios for alirocumab also decreased monotonically across achieved apoB strata. Achieved apoB was predictive of MACE after adjustment for achieved low-density lipoprotein cholesterol or nonâhigh-density lipoprotein cholesterol but not vice versa. Conclusions: In patients with recent acute coronary syndrome and elevated atherogenic lipoproteins, MACE increased across baseline apoB strata. Alirocumab reduced MACE across all strata of baseline apoB, with larger absolute reductions in patients with higher baseline levels. Lower achieved apoB was associated with lower risk of MACE, even after accounting for achieved low-density lipoprotein cholesterol or nonâhigh-density lipoprotein cholesterol, indicating that apoB provides incremental information. Achievement of apoB levels as low as â€35 mg/dL may reduce lipoprotein-attributable residual risk after acute coronary syndrome. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT01663402.gov; Unique identifier: NCT01663402.URL: https://www
Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial
- Author
- Abbas Jalal
- Abbate Antonio
- Abdallah Mouhamad
- Abdullakutty Jabir
- Abhyanakar Atul D
- Aboyans Victor
- Abrantes José Antonio M
- Abu-Fadel Mazen
- Accini Mendoza Jose L
- Acevedo Monica
- Adamkova Vera
- Adamo Antony
- Adhyapak Srilakshmi
- Agarwal Himanshu
- Agergaard Jensen Steen
- Aggarwal Rahul
- Aggarwal Rajesh K
- Agnetti Veronique
- Aguirre Arnoldo
- Ahmed Hinan
- Ahremark Ulf
- Ahuad Guerrero Rodolfo A.
- Airaksinen Juhani
- Aitken Denise
- Akatova Evgenia
- Akhter Faiq
- Ako Junya
- Akright Laura
- Akyea-Djamson Ayim
- Al Joundi Tammam
- Al-Windy Nadea YY
- Alan David
- Albert Seals
- Alcocer Gamba Marco Antonio
- Alexander John H.
- Alexander Karen
- Alexandru Tom M
- Alexopoulos Dimitrios
- Alings Marco
- Alonso Martin Joaquin J
- Alonso Orcajo Norberto
- Alonso Alvaro
- Alsweiler Caroline
- Alvarisqueta Andrés F.
- Alves De Lima Alberto E.
- Amarasekera Stanley
- Amarasena Naomali
- Amidon Thomas
- Amir Offer
- Amlani Mohamadali
- Amosova Ekaterina
- Amuchastegui Marcos
- Anchante Hernandez Henry A
- Andersen Dorthe
- Andersen Kjell
- Andersen Rolf
- Anderson Jay
- Ando Kenji
- Andrzej Lipko Jan
- Annam Sharath
- Anscombe Russell
- Apostolovic Svetlana R.
- Appel Karl-Friedrich
- Arandjelovic Aleksandra
- Araneda Guillermo
- Arango Benecke Juan L
- Arbel Yaron
- Arif Imran
- Armaganijan Luciana
- Aroney Constantine
- Arstall Margaret A
- Asanin Milika R.
- Assi Nizar
- Atar Shaul
- Athyros Vasilios
- Auguadro Carla
- Ayaz Mohammad
- Aylward Philip E.
- Ayoub José Carlos Aidar
- Azizad Masoud M
- BabiÄ Zdravko
- Baccara-Dinet Marie
- Badreddine Emmy
- Bagai Akshay
- Bagriy Andriy
- Bahit Maria Cecilia
- Bai Feng
- Balaguer Recena Javier
- Baldari Duccio
- Balinovac Jovan
- Ball Eric
- Ball Eric
- Bang Lia E
- Banuru Sridhar
- Barakovic Fahir
- Baranov Evgeny
- Baranova Elena
- Barbarash Olga L
- Barbato Emanuele
- Barna Olga M
- Barone-Rochette Gilles
- Barr Craig
- Barraud Pauline
- Barrera Silva Sandra I
- Barrucco Robert
- Bartels Gerard L
- Basart Dirk
- Bashir Riyaz
- Bata Iqbal
- Batushkin Valeriy
- Bayat Junaid
- Bayram Llamas Edmundo Alfredo
- Bayron Carlos
- Beauloye Christophe
- Bednarski Janusz
- Behrens Steffen
- Bejuit Raphael
- Bekkouche Mhamed
- Belhassane Abdelkader
- Beltran Pascale
- Benbernou Fadela
- Benedicto Amparo
- Bengrait Nafissa
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- Bengus Cristina M
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- Bhatt Deepak L.
- Binde Ronald
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- Blicharski Tomasz
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- Blonder Ronald
- Blumberg Eduardo DS
- Boccara Franck
- Bodanese Luiz C
- BodĂ Peris Vicente
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- Bokarev Igor
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- D'Urso Michael
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- Danchin Nicolas
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- Dimkovic Sinisa
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- Dimulescu Doina
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- Ding Chunhua
- Dion Danielle
- Do Rose
- Dodds III George
- Dodic Slobodan
- Dohad Suhail
- Doi Yasuji
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- Hussein Osamah
- Huynh Thao
- Hwang Juey-Jen
- Ilic Stevan
- Ilieva-Pandeva Katya A
- Ilya Masterov
- Ince Carlos
- Iqbal Syed MR
- Irimpen Anand
- Islam Othman
- Islam Shahidul
- Istratoaie Octavian
- Ito Kashima
- Ivanov Igor G
- Ivanova Raya
- Ivanovic Nikola
- Iyengar Shamanna S
- Izzo Mark
- Iñiguez Andres
- Jacoby Douglas
- Jafar Zubair
- Jaffrani Naseem
- Jain Diwakar
- Jaiwal Gayatri
- Jakimov Tamara
- Janik Matthew
- Janosik Denise
- Jaramillo Nicolas
- Javierre Carine
- Jaworska Krystyna
- Jayawardena Jayanthimala
- Jeong Myung Ho
- Jeppesen JĂžrgen
- JeriÄ Melita
- Jeserich Michael
- Jiang Weihong
- Jintapakorn Woravut
- Johansen Peter
- Jonas Michael
- Jong Geert T
- Jordan Joseph Dedrick
- Jortveit Jarle
- Joshi Abhijeet B
- Joshi Parag
- Jovin Ion
- Jujjuru Srimannarayana
- Jukema J Wouter
- Jukema J. Wouter
- Jukema Johan
- Jure Horacio O.
- Jurgaitiene Ruta
- Jurgenson Tiina
- Kadr Honer
- Kaewsuwanna Pinij
- Kahali Dhiman
- Kaiser Sergio
- Kalashetti Suhas
- Kalil Renato
- Kamensky Gabriel
- Kamiya Haruo
- Kandasamy Balachandran
- Kanorsky Sergey
- Kapin Tibor
- Kaplan Refik
- Kapp Ilse E
- Karadzic Ana
- Karakas Mahir
- Karalis Ioannis
- Karlsberg Ronald
- Karna Sunil
- Karpenko Oleksandr
- Karpenko Yuriy
- Karpov Yuri
- Karpov Yuriy
- Kartalis Athanasios
- Kasim Sazzli
- Kathryn Rohr
- Katona AndrĂĄs
- Katsuda Yousuke
- Katz Amos
- Kaucak Vladimir
- Kavaliauskiene Roma
- Kawakami Anelise
- Kawasaki Tomohiro
- Ke Yuannan
- Keating Friederike
- Kedev Sasko
- Keen William
- Kehasukcharoen Wirash
- Kelsey Sheryl F.
- Kerkar Prafulla
- Khabeishvili George
- Khaira Ajit S
- Khaisheva Larisa
- Khan Abul
- Khan Aziz
- Khan Misal
- Khasanov Niiaz
- Khera Amit
- Khintibidze Irakli
- Khlevchuk Tatiana
- Khurana Sandeep
- Kibarskis Aleksandras
- Kichukov Kostadin N
- Killat Holger
- Kim Chongjin
- Kim Hack-Lyoung
- Kim Hae Young
- Kim Hyo Soo
- Kim Hyo-Soo
- Kim Moo Hyun
- Kim Sang-Hyun
- Kim Youngkwon
- Kimmelstiel Carey
- Kimura Kazuo
- Kimura Takeshi
- Kimura Takeshi
- King Marilyn
- Kinzfogl III George
- Kirma Cevat
- Kishi Koichi
- Kiss Robert Gabor
- Kjovkaroski Aleksandar
- Klancke Kim
- Klantsa Andriy
- Klausen Ib C
- Kline Geoffrey
- Klutstein Marc
- Knickelbine Thomas
- Knowles Joshua W.
- Knutson Thomas
- Koba Shinji
- Kobalava Zhanna
- Kobayashi John
- Koike Akihiro
- Koldas Lale
- Kolls Bradley J.
- Kondo Nicholas I
- Kong David F.
- Kopytsya Mykola
- Koren Michael
- Kormann Adrian
- Kornder Jan
- Kornowski Ran
- Korol Marek
- Kosinski Edward
- Kosmachova Elena
- Kostarska-Srokosz Edyta
- Kostis John
- Kotha Purushotham
- Kouz Simon
- Kovalskyi Ihor
- Kozuma Ken
- Kralova Katarina
- Krasowski Wlodzimierz
- Krawczyk Justine
- Krichmar Perry
- Kristensen Kjeld S
- Kristjan Arved
- Kubica Jacek
- Kubilius Raimondas
- Kuchar Jiri
- Kuhlman Peter
- KuliÄ Mehmed
- Kultursay Hakan
- Kumar Anil
- Kumar Priya
- Kumar Vinay
- Kumbla Mukund
- Kumkumian Greg
- Kuo Jen-Yuan
- Kurian John
- Kushnir Mykola
- Kutniy Oles
- Kuvin Jeffrey
- Kyiak Yulian
- Labeirie Julien
- Labroo Ajay
- Lai Christopher
- Lai Wen-Ter
- Lambert Charles
- Lamoureux Maud
- Landmesser Ulf
- Landzberg Joel
- Larry John
- Larsen John
- Laucevicius Aleksandras
- Laufs Ulrich
- Laxson David
- Lazov Petar V
- Leaes Paulo E
- Leclercq Florence
- Lecorps Guillaume
- Lecorps Guillaume
- Lee Kaeng
- Lee Kwan
- LefĂšvre Thierry
- Leggewie Stefan
- Lehman Sam J
- Leimbach Wayne
- Lekakis John
- Leonard Parilak
- Leonardi Sergio
- Leone Attilio
- Lepage Serge
- Lepor Norman
- Leshchuk Oleh
- Lester F. Martin
- Leung Raymond
- Levite Howard
- Levy Terry
- Li Huanming
- Li Jianping
- Li Tianchang
- Li Xiang
- Li Xiaodong
- Li Ying
- Lianopoulos Emmanouil
- Liberman Alberto
- Liberopoulos Evangelos
- Libov Igor
- Licciardello Giovanni
- Lieber Ira
- Liem Anho AH
- Liew Houng B
- Lillis Linda
- Lin Jinxiu
- Lin Wei Hsiang
- Lin Wenhua
- Lin Xuefeng
- Lindsey Jason
- Linhart Ales
- Link Chad
- Lionarons Raymond
- Lip Gregory YH
- Lishner Michael
- Liu Ming-En
- Liu Shaowen
- Liu Xuebo
- Llamas EsperĂłn Guillermo Antonio
- Llerena Navarro Nassip C
- Llois Susana
- Loizeau Virginie
- Loizeau Virginie
- Loma-Osorio Rincon Pablo
- Lomakin Nikita V
- Lomholdt Jens D
- Lominadze Zaza
- Lopes Renato
- Lopes Renato D
- Lopes Renato D.
- Lorenzato Christelle
- Lorenzatti Alberto J.
- Lotan Chaim
- Lottering Hanlie
- Lotun Kapildeo
- Loussararian Arthur
- Love Michael
- Lozance Nensi
- Lu Qinghua
- Lubinski Andrzej
- Luciardi Hector L
- Lui Henry
- Lukenda Josip
- Luna Botia Diana C
- Luo Zhurong
- Lupkovics Geza
- Lupovitch Steven
- Luquez Hugo A
- Lutchmedial Sohrab
- Luyten Anne
- Lyamina Nadezhda
- LĂłpez Rosas Enrique
- LĂłpez-Jaramillo Patricio
- Macdonald Paul
- Macdonell Alexander
- Mach Francois
- Machado Leandro
- Machecourt Jacques
- Machova Vilma
- Mackinnon Ignacio J.
- Mahaffey Kenneth W.
- Mahajan Ajaykumar
- Mahal Sharan
- MajercĂĄk Ivan
- Makotoko Ellen Makoali
- Malhotra Vinay
- Malik Amir
- Malis Mihaela
- Malozzi Christopher
- Malynovsky Yaroslav
- Manakshe Gajendra V
- Manenti Euler Roberto Fernandes
- Mano Toshiaki
- Manolis Athanassios
- Mansourati Jacques
- Manzur Jatin Fernando G
- Marais H. John
- Marco Valgimigli
- Marcus Jill
- Marin-Neto Jose A
- Markov Dimitar T
- Markov Valentin
- Marmor Alon
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- Martins Dinis
- MartĂnez SĂĄnchez Carlos Rodolfo
- Marusincova Ivana
- Marx Nikolaus
- Marx Nikolaus
- Marx Roger
- MarĂn Francisco
- Maskon Oteh
- Massey Clara
- Masutani Motomaru
- Matas Pericas Laia
- Matei Adrian V
- Mathews Robin
- Mathur Anthony
- Mathur Rishabh
- Matiga Generoso
- Matthews Alexander
- Matuska Jiri
- May Ole
- May Wade
- Mayurathan Gnanamoorthy
- Mazur Juraj
- Mcclanahan Mark A
- Mcclure Sam
- Mcgarvey Joseph
- Mcgough Martin
- Mclaurin Brent
- Medrano Allende Juan C.
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- Mejic-Krstulovic Stanka
- Meloni Chiara
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- Metra Marco
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- Michalaros Yorghos L
- Michaud Nicolas
- Michishita Ichiro
- Micko Karol
- Midzic Zlatko
- Miklaszewicz Beata
- Mileta Dean
- Militaru Constantin
- MiliÄiÄ Davor
- Mincheva Valentina M
- Minescu Bogdan
- Mintale Iveta
- Mirek-Bryniarska Ewa
- Misonis Nerijus
- Mittal Suneet
- Moccetti Tiziano
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- Molina De Salazar Dora I
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- Montaña Oscar R.
- Montecinos Humberto
- Monteiro Minguel R
- Monteiro Pedro
- Montenegro Valdovinos Pablo Carlos
- Moodley Rajendran
- Morais Joao
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- Moriarty Andrew
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- Morino Yoshihiro
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- MĂŒller GĂĄbor
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- Nacoud Ackar Alfredo
- Nager Paul
- Nagy Lajos
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- Nahuelpan Leonardo
- Nakao Koichi
- Nani Sebastian
- Naplava Robert
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- Nicol Peter
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- Nikolaev Konstantin
- Nikolov Fedya P
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- Nishibe Akira
- Nociar Jan
- Nogareda Gustavo
- Norkiene Sigute
- Normand Mickael
- Novaretto Leonardo P.
- Novo Salvatore
- Novoa Federico
- Novotny Vojtech
- Nowins Rosemary
- Nuding Sebastian
- NygÄrd Ottar
- NĂșñez Fragoso Juan Carlos
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- Okan Betim
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- Olivari Zoran
- Oliveira Janaina
- Oliver Richard
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- Ono Yujiro
- Oomen Antonius
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- Oqueli Flores Romulo E
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- Osokina Natalya
- Ossei-Gerning Nicholas
- Ostadal Petr
- Ourliac Anne
- Paganelli Franck
- Pagava Zurab
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- Palmer Bruce
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- Panchal Vipul
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- Pandey Amritanshu
- Pandurangi Ulhas
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- Pederson Robert
- Pella Daniel
- Pellan Valerie
- Peng Daoquan
- Penny William
- Pepine Carl
- Pereira Edward
- Pereira Helder H
- Perez Luis
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- Perlmutter Neal
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- Perthuis Aurelie
- PerĆĄiÄ Viktor
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- Petrulioniene Zaneta
- PeÄin Ivan
- Piatti Piermarco
- Picault Patrick
- Picone Mark
- Piepiorka Marek
- Pillay Thayabran
- Pimentel Filho Pedro
- Pincetti Cristian
- PintariÄ Hrvoje
- Piovaccari Giancarlo
- Pirenne Bruno
- Piyayotai Dilok
- Plaza Perez Ignacio
- Podoleanu Cristian GC
- Podpera Ivo
- Poh Kian-Keong
- Pojskic Belma
- Poklukar Janez
- Pollock Stewart
- Ponce George
- Ponnamperuma Chandrike
- Pontaga Natalija
- Pope Theodore
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- PrvuloviÄ Äeiti
- Puccioni Enrico
- Puri Sanjeev
- Purow Joshua
- Putnikovic Tosic Biljana
- Puymirat Etienne
- PĂ©rez RĂos JesĂșs Antonio
- Qu Baiming
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- Radovanovic Slavica
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- Ramin Ebrahimi
- Ramos LĂłpez Gabriel Arturo
- Ranadive Nandkishore
- Ranasinghe Gotabhaya
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- Rauch-Kröhnert Ursula
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- Reshetko Olga
- Reshotko Dmytro
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- Riaz Garda
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- Roosen John
- Rorick Tyrus
- Rose Gregory
- Rosenberg Michael
- Rosenschein Uri
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- Rossi Joseph
- Rossi Paulo RF
- Rossi Peter
- Rosu Doina
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- Rozeman Phillip
- Rozenman Yoseph
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- Saavedra Silvia S
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- Sabbah Eric
- Sachin Patil
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- Salcido VĂĄzquez Eduardo
- Salomone Oscar
- Salvioni Alessandro
- Saminski Krzysztof
- Sanabria Perez Enrique S
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- Sansanayudh Nakarin
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- Scalise Filippo
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- Schaeufele Tim
- Schellenberg Detlev
- Schiavi Lilia B.
- Schiele Francois
- Schifferdecker Branislav
- Schmalfuss Carsten
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- Schmitt Susanne
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- Schuyler Jones William
- Schwartz Gregory G
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- Schwartz Michael
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- Seixo Filipe
- Selecky Juraj
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- Senaratne Vajira
- Senni Michelle
- Serrano Antolin Jose Maria
- Sethi Sumeet
- Shaburishvili Tamaz
- Shah Anil V
- Shah Bimal R.
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- Shalaev Sergey
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- Shaw James
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- Shchekotov Vladimir
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- Shetty Sanjay
- Shi Xubo
- Shimatani Yuji
- Shimizu Masatoshi
- Shinde Rituparna
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- Shvarts Yury
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- Simon Tabassome
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- Singh Narendra
- Singsaas Erlend gyllensten
- Sinha Dhurjati
- Sinnaeve Peter
- Sionis Dimitrios
- Sirisena Thilak
- Siu David CW
- Skonieczny Grzegorz
- Skorski Marcin
- Skoumas Ioannis
- Slapikas Rimvydas
- Smik Rudolf
- Smith Lucile
- Smith Simon
- Soggia Ana Priscila
- Soonfuang Wasant
- SoopĂ”ld Ăllar
- Soots Mai
- Sopena Sebastien
- Soran Handrean
- Soroka Eugene
- Sotnikova Tatiana
- Sotomayor Herazo Aristides
- Sotty Marc
- Sousa Luciano
- Souza Weimar KSB
- Soward Allan
- Sparby Jon Arne
- Speirs Shawn
- Spinar Jindrich
- Sporn Daniel
- Spriggs Douglas
- Sprigings David
- Sritara Piyamitr
- Stanescu-Cioranu Rodica
- Staneta Pawel
- Stanislavchuk Mykola
- Stankovic Aleksandar
- Stapleton Dwight
- Starcevic Boris
- Starmer Gregory
- Stasek Josef
- Stasiewski Arkadiusz
- Steg Ph. Gabriel
- Steg Philippe Gabriel
- Steiner Stephan
- Stellbrink Christoph
- Stewart Ralph
- Stojic Stevo
- Stone James
- Storey Robert
- Strader James
- Strain Janet
- Stratmann Matthias
- Strbova Jaroslava
- Strelnieks Aldis
- Striekwold Harry
- Stringfellow Kenya
- Strozzi Maja
- Stryuk Raisa
- Su Guohai
- Su Xi
- Suarez Arambula Rafael
- Suarez Otero Rodrigo
- Subherwal Sumeet
- Subkovas Eduardas
- Sudnik Wanda
- Sugino Hiroshi
- Suh David
- Sujjavanich Darin
- Sukonthasarn Apichard
- Sulit Dennis Jose
- Sultan Ayyaz
- Sumner Andrew
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- Suryapranata Harry
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- Szwed Hanna
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- Takahashi Toshiyuki
- Takata Theodore
- Takeda Yoshihiro
- Tamby Jean-François
- Tamura Ritsu
- Tan Edgar
- Tang I-Shing Justin
- Tashchuk Viktor
- Tasic Nebojsa
- Ternouth Ian
- Terzic Ibrahim
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- Thew Stephen
- Timothy Eichenlaub
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- Tissera Nirmali
- Todic Branislava
- Todorov Georgi V
- Toledo Pablo
- Toma Mustafa
- Tomala Tadeusz
- Tomulic Vjekoslav
- Tonnessen Glen
- Torstensson Ingemar
- Toursarkissian Nicole
- Tov Naveh
- Treasure II Charles
- Tretyakova Tatyana V
- Trevelyan Jasper
- Tricoci Pierluigi
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- Troquay Roland PTh
- Trotter Charlene
- Tsai Wei-Chuan
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- Tumbev Haralin S
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- Turi Tibor
- Turk Samir
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- Tyrenko Vadim V
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- Ueng Kwo-Chang
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- Utsu Noriaki
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- Vakili Babak
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- Vered Zvi
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- Vikman Saila
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- Vizel Saul
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- Voevoda Mikhail I
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- Vohra Rakesh
- Vora Kishor
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- Voyce Stephen
- Vrolix Mathias CM
- Vulic Dusko
- Vuurmans Tycho
- Våzquez de Prada José Antonio
- Vöhringer Hans Friedrich
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- Wada Atsuyuki
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- Wali Andreas
- Walichiewicz Piotr Maria
- Waltenberger Johannes
- Waltman Jonathan
- Wan Mohamed Wan Mohd Izani
- Wang Jian'An
- Wang Jianzhong
- Wang Jingfeng
- Wattanakit Keattiyoat
- Wei Meng
- Weidinger Franz
- Weil Joachim
- Weintraub Howard
- Weiss Robert
- WeiĂbrodt Matthias
- Welka Stephen
- Welker James
- Welker James
- Wells Terry
- Wells Terry
- Werner Christian
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- Westerhausen Donald
- Whitaker Jack
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- White Lindsey
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- Wiersma Jacobijne J
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- Winkelmann Bernhard
- Wiseman Alan
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- Wlodarczak Adrian
- Wojewoda Pawel
- Wolfovitz Efrat
- Wollaert Bart
- Wong Yuk-Ki
- Wongpraparut Nattawut
- Worner Diz Fernando
- Wozniak Julianna
- Wright Scott
- Wu Chun
- Xavier Denis
- Xenakis Mark
- Xiang Meixiang
- Xu Biao
- Xu Dingli
- Xu Xiping
- Xu Yizhou
- Yagensky Andriy
- Yakushin Sergey
- Yan Andrew T.
- Yan Bryan PY
- Yang Eric
- Yang Xiangjun
- Yang Xinchun
- Yao Zhuhua
- Yazdani Shahram
- Yañez Mario
- Yerra Shiv Kumar
- Yin Wei-Hsian
- Yong Huo
- Yoon Jung Han
- Younis Liwa
- Yu Yihua
- Yuan Zuyi
- Yusoff Khalid
- Zahger Doron
- Zahr Firas
- Zaidman Cesar J.
- Zainea Mark
- Zaman Azfar
- Zamorano Jose Luis
- Zapata Gerardo
- Zea Nunez Carlos A
- Zeiher Andreas M
- Zeiher Andreas M.
- Zhang Ruiyan
- Zhang Wenwu
- Zhang Xuelian
- Zhang Zheng
- Zhao Shuiping
- Zhao Xingsheng
- Zheleznyy Volodymyr
- Zheng Yang
- Zheng Zeqi
- Zhong Yi
- Zhou Yujie
- Zhu Hong
- Zhu Jianhua
- Zirlik Andreas
- Zizka Jiri
- Zobouyan Isabelle
- Zong Wenxia
- Zrazhevsky Konstantin
- Zukermann Robert
- Zurakowski Aleksander
- Zvi Vered
- Zwart Peter
- Zweiker Robert
- Ădes IstvĂĄn
- ÄerniÄ Ć uligoj NataĆĄa
- Ć ikiÄ Jozica
- Ć tambuk Kresimir
- Ćœuran Ivan
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Background After acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events. A reduction in mean LDL cholesterol to 1.4-1.8 mmol/L with ezetimibe or statins reduces cardiovascular events in patients with an acute coronary syndrome and diabetes. However, the efficacy and safety of further reduction in LDL cholesterol with an inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) after acute coronary syndrome is unknown. We aimed to explore this issue in a prespecified analysis of the ODYSSEY OUTCOMES trial of the PCSK9 inhibitor alirocumab, assessing its effects on cardiovascular outcomes by baseline glycaemic status, while also assessing its effects on glycaemic measures including risk of new-onset diabetes
COVID-19 Host Genetics Initiative. A first update on mapping the human genetic architecture of COVID-19
- Author
- A Cerny (13566592)
- A Conen (13566478)
- A Guillet (13566487)
- A Munting (13566535)
- A Perret (13566628)
- Aarno Palotie (41342)
- Abdolmajid Hosseini (13566952)
- Abdulaziz AlMalik (5215085)
- Abdulraheem Alshareef (3532520)
- Achille Iolascon (206310)
- Adam S Butterworth (3810055)
- Afshar Etemadi Aleagha (13566937)
- Agnese Verzuri (13566721)
- Agostino Ognibene (5624702)
- Agostino Riva (393458)
- Ahmadreza Niavarani (711998)
- Ahna Girshick (13566238)
- Ahsan Khan (12068159)
- Aida Fiz-Lopez (13567297)
- Alba Parra Martinez (13567294)
- Albandary M Alowayn (13567099)
- Albert Smith (5520185)
- Albert Tenesa (107674)
- Alessandra Guarnaccia (13566751)
- Alessandra Renieri (383439)
- Alessandra Stella (28791)
- Alessandra Vergori (4540474)
- Alessandro Pancrazzi (13566727)
- Alessia Giorli (13566760)
- Alex Serra-Llovich (13567288)
- Alex Soriano (3091062)
- Alex Stuckey (13567192)
- Alexander Labkowsky (13567030)
- Alexander T Williams (8950472)
- Alexander W Charney (13567054)
- Alexandra Aksentijevich (13567027)
- Alexandre Belisle (13566310)
- Ali Amirsavadkouhi (13566931)
- Ali Sobh (13566367)
- Alice Donati (6876746)
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- Alicia R Martin (12556807)
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- Amara Khan (10835145)
- Amin K Khattab (13567138)
- Amr M Yassen (13566409)
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- Amy Trankiem (13566163)
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- Xavier Farre (10317580)
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- Xiaoqing Xue (6116318)
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- Zeinab Naderpour (10054118)
- Ziab Z Alahmadey (13567144)
- Publication venue
- Publication date
- 03/08/2022
- Field of study
The COVID-19 pandemic continues to pose a major public health threat, especially in countries with low vaccination rates. To better understand the biological underpinnings of SARS-CoV-2 infection and COVID-19 severity, we formed the COVID-19 Host Genetics Initiative1. Here we present a genome-wide association study meta-analysis of up to 125,584 cases and over 2.5âmillion control individuals across 60 studies from 25 countries, adding 11 genome-wide significant loci compared with those previously identified2. Genes at new loci, including SFTPD, MUC5B and ACE2, reveal compelling insights regarding disease susceptibility and severity.</p
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- AbellĂĄn Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
- Ahmed Khalil
- Ahmed Manar
- Ahmed Masood
- Ahmed Safia
- Ahn Hong Min
- Aibe Raquel
- Aigner Felix
- Aissat Abdenour
- Aitbaeva Arai
- Akay Omer
- Akbar Ali
- Akbas Ahmet
- Akere Abidemi
- Akesen Selcan
- Akgun Erhan
- Akhtar Naseem
- Akın Emrah
- Akova Elif
- Aktas Serhat
- Akçay Ăzlem
- Al Masri Mahmoud
- Al-Alnsi Ahmed
- Al-Hutheifi Roqia'A
- Al-Jarrah Amar
- Al-Naggar Hamza
- Al-Shehari Mohammed
- Alamin Nadeen
- Alawi Raneen
- Alawlaqi Dina
- Alawneh Fade
- Alberola Maria José
- Albers Michael
- Alcolea Natalia GonzĂĄlez
- Aleem Muhammad
- Alegre InĂȘs
- Alegre Javier Martinez
- Alexandre Flavia
- Alexandrescu Corina
- Alexnder Abelevich
- Alexopoulou Kalliopi
- Alfonso Beatriz AmorĂłs
- Ali Ahmed
- Ali Che Saniati Che
- Ali Danish
- Ali Madeeha
- Ali Mahmoud Abdelwahab
- Ali Manhal Hashim
- Ali Noura Al
- Alikhanli Jhale
- Aliyeva Zumrud
- Aliyu Mohammed
- Aljawder Hasan
- Allen Kate
- Almahmeed Ebrahim
- Alonso Alfredo
- Alonso Javier Etreros
- Alsamneh Muneer
- Alsayadi Ramzi
- Altinel Yuksel
- Altintoprak Fatih
- Altomare Donato F
- Alvarenga Isabella
- Alvarez Laura Jimenez
- Alvarez-Bautista Francisco Emmanuel
- Alvarez-DĂez Marcos
- Alves Brenda Chayanny
- Amadigwe Rita
- Amado Andreia
- Amado FabĂola
- Amador Cristina GarcĂa
- Amanullah Nazli
- Amaral HĂ©lida Aline Tomacheski
- Amaral Luis
- Amin-Tai Hizami
- Aminu Bashiru
- Amir Ahmad Suhaimi
- Ammar Ahmed Siddique
- Ammar Mona Ahmed
- Ammendola Michele
- Ammerata Giorgio
- Amorim Edgar
- Ancans Guntis
- Anderson Tom
- Andrade Diogo
- Andrejevic Predrag
- AndrĂ©s Beatriz DĂaz San
- Anestiadou Elissavet
- Ang Chin Wee
- Angelo Franceschi
- Anokhin Evgeny
- Anoldo Pietro
- Antakia Ramez
- Anton Majd
- Antonelli Serena
- Antropoli Carmine
- Anula Rocio
- Anwar Jamal
- Anyadike Florence
- Apostolakidou Magda
- Apostolidi Eirini
- Aprea Giovanni
- Arabadzhiev Angel
- Arakawa Satoshi
- Arauz Jazmin
- Aravindan U
- Aremu Abdurrahman
- Aremu Isiaka
- Argawy Osama
- Arican Can
- Arida Zahed Abu
- Armellin Claudia
- Arnaoutoglou Eleni
- Arreguy-Borges Kanthya
- Artigot Mariano
- Arturi Alessandro
- Arulappan Nirupama
- Arya Shobhit
- Arynov Ardak
- Asaad Peter
- Asano Yukio
- Ascari Francesca
- Asgarov Mohsum
- Ashmawy Soad
- Aslam Muhammad Imran
- Assimakopoulou Elena
- Assis Ana
- Astilleta Romina
- Atanasov Boyko
- Atendido Tiffany
- Athanasakis Elias
- Atici Semra Demirli
- Avellaneda Nicholas
- Avellaneda Nicolas
- Avseren Goksu
- Awead Marwa
- Ayandipo Omobolaji
- Aybar Engin
- Aydin Funda
- Aydin Gaye
- Ayoub Kusay
- Aytac Erman
- Aytaç Erman
- Azevedo Jose
- Azevedo Patricia
- Azhar Najia
- Aziz Gowhar
- Azman Zairul Azwan Mohd
- AĆkar Ahmet
- Babatunde Olanrewaju
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- Baek Jeong-Heum
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- Bala Abubakar Muhammad
- Balaban Vladimir
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- Balasubramaniam Dinesh
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- Baldi Claudio
- Balestri Riccardo
- Balfour James
- Ballah Abubakar
- Ballian Nikiforos
- Balooshi Iman Al
- Baloyiannis Ioannis
- Bamford Richard
- Bandar Mahdi Al
- Banham Gail
- Bannoud Mohammad Hassan
- Baptista Victor
- Baral Jörg
- Barbalace Nicolas
- Barbato Giuseppe
- Barbosa Anderson
- Bareka Metaxia
- Baris Baver
- Barradas Renato
- Barreda Sara Castillo
- Barrena-Blazquez Silvestra
- Barton Jess
- Bartosiak Katarzyna
- Bashilkina Olga
- Bashir Mohammed
- Basile Raffaele
- Basnyat Pradeep
- Batool Sana
- Bautista Wilson Manuel SĂĄnchez
- Bayhan ZĂŒlfĂŒ
- Bayo José Manuel Muros
- BayĂłn Raquel Ălvaro
- Baños Pedro Antonio Parra
- Beard David
- Bedzhanyan Arkady
- Behilil Chakib
- Bekele Kebebe
- Belarmino Armin
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- Belev Nikolay
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- Belvedere Angela
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- Bennett James
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- Bergamini Carlo
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- Bethune Robert
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- Blasco Laura Fraile
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- Boccia Giuseppe
- Bogatikov Alexander
- Bolanle Olajide Edward
- Bomfa-Barbosa Alysson
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- Bonci Eduard-Alexandru
- Bordom Daniel Osei
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- Bose Bodhisattva
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- Caliendo Domenico
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- Campbell Marion
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- Canda Aras Emre
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- Cao Victor Hugo Bruno
- Capolupo Gabriella Teresa
- Cappiello Antonio
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- Carbone Ludovico
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- Cardoso Diogo
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- Carlos Sandra
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- Cecchini Ilaria
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- Celik Hale Kefeli
- Ceretti Andrea Pisani
- Ceron Silvia Ferrer
- Cervellera Maurizio
- Cervone Carmela
- Chacko Anil
- Chandrasinghe Pramodh
- Charakopoulou Alexandra
- Chardalias Leonidas
- Chaturvedi Arun
- Chatzikomnitsa Paraskevi
- Chaudhari Abhishek
- Chaudhry Sanjay
- Chawla Tabish
- Chee Corissa
- Chen Nevin
- Cheng Kuang I
- Chiarugi Massimo
- Chisthi Meer
- Chitnis Abhishek
- Chitul Andrei
- Chmielewski Gaspard
- Cholewa Hanna
- Chornet Marta RosellĂł
- Chowdhary Manish
- Chowdhury Sharfuddin
- Chowdhury Sharfuddin M
- Chowdri Nisar
- Christensen Peter
- Christodoulidis Grigorios
- Chrysos Emmanuel
- Chua Lorna
- Chubukova Natlia
- Chung Jun Seong
- Church Robert
- Chwat Carina
- Ciabattari Paula
- Cianchi Fabio
- Cianci Pasquale
- Ciccarese Angelo Antonio
- Ciftci Ahmet Burak
- Cigagna Luca
- Cini Charles
- Ciotarla Danut Constantin
- Cirocchi Nicholas
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- Ck Harikumar
- Clark Thomas
- Clarke Nicola
- Coccolini Federico
- Codes Lina
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- Coladonato Massimiliano
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- Conceição Luis
- Conde Juan Guillermo Ais
- Connolly Lewis
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- Convertini Ornella
- Cook Esther
- Cooke Fiachra
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- Coratti Francesco
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- Cortés Guillermo Felipe Valderas
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- CustĂłdio Pedro
- CutellĂš Clelia
- Czarnecki Roman
- D'Angelo Salvatore
- D'Ugo Stefano
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- da Silveira Sete Alexandre
- Dainius Edvinas
- Dalton Richard
- Damieta Marta Pascual
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- Danelli Piergiorgio
- Danial Aghyad Kudra
- Daniels Ian R
- Daniyan Muhammad
- Danna Riccardo
- Danys Donatas
- Dardanov Dragomir
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- DaugÄla Edvardas
- Dauri Mario
- Davidovskaja Larisa
- Davies Emma
- Davis Cian
- Dawson Brett E
- Dawson Carmel
- de Andrés-Asenjo Beatriz
- de Deken Julie
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- de Kort Chantal
- de La Plaza Llamas Roberto
- de Lacy Antonio Maria
- de Lebrusant FernĂĄndez Sara
- de LeĂłn RendĂłn Jorge Luis
- de Luca Michele
- de Lucia Chiara
- de Miranda Silvestre Simone Chaves
- de Oliveira GĂłes Igor Arantes
- de Oliveira FlĂĄvia Gomes
- de Oliveira JoĂŁo Carlos Costa
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- de Simone Giuseppe
- de Souza Artioli Luana Maria
- de Souza Pires Bruno Lucena
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- Hooper Richard L
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- Kopteyev Nikita R
- Korkolis Dimitrios
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- Loh Will
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- Longchamp Grégoire
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- Mcdermott Frank D
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- Meurette Guillaume
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- Mohamad Aya Haji
- Mohamed Haiba A
- Mohamed Mohamed
- Mohamed Nada
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- Yew Chor Kuan
- Yılmaz GĂŒlseren
- Yilmazlar Tuncay
- YiÄit Direnç
- Yoldas Tayfun
- Yonekura Hiroshi
- Yorkmui Liu
- Yoshino Kenji
- Younes Lina
- Young Trudi
- Yule Michael
- Yusoff Zakiah Mohd
- Zaari Fatimazahraa
- Zabiyaka Mikhail
- ZadroĆŒna Monika
- Zafar Madiha
- Zagaynov Eugeny
- Zaidi Syed-Nadeem
- Zaimis Tilemachos
- Zain Wan Zainira Wan
- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
- Zanoni Andrea
- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah KaÄan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Ălvarez-Llano Laura
- Ăngelo Miguel Duarte
- ĂSullivan Sara Nuñez
- Ăzçelik Mehmet Faik
- Äoza Ivo
- Ćanlı Ahmet Necati
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)