666 research outputs found

    Epistemological ties between Psychoanalysis and Queer Theory: Freud, Preciado and the american radical feminism

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    This paper examines the intersection of Freudian and Lacanian psychoanalysis with Queer Theory. Starting from an analysis of the Freudian reception in the Second-wave Feminism (1960-1980), the current revival of the anti-psychoanalytic debate is focused, with particular reference to the thought of the transgender philosopher Paul B. Preciado. The aim is to reveal how psychoanalysis turns out to be a valid ally of feminism from an epistemological point of view, and - more radically - how a new 'psychoanalytic feminism' can be configured. An investigation into the condition of women in contemporary times cannot but pass from the formations of the unconscious, from the Symbolic and from the structuring of Desire, towards a psychoanalysis recoinceived as a crossroad of political implications and transfeminist processes of subjectification.In questo articolo si vagliano le linee di intersezione della psicoanalisi freudiana e lacaniana con la Queer Theory. Muovendo da un’analisi sulla ricezione del freudismo nel movimento femminista radicale americano del biennio 1960-1980, ci si sofferma sull’odierna ripresa della polemica anti-psicanalitica nella teoria del filosofo transgender Paul B. Preciado. L’obiettivo è quello di mostrare come la psicoanalisi risulti, invece, in sede epistemologica, una valida alleata del femminismo, e - più radicalmente - come si possa configurare un nuovo ‘femminismo psicoanalitico’. Un’indagine sulla condizione della donna in età contemporanea non può non passare dalle formazioni dell’inconscio, dal Simbolico e dalla strutturazione del Desiderio, verso una psicoanalisi di nuovo conio, crocevia di implicazioni politiche e processi di soggettivazione transfemministi

    Genetic predisposition and induced pro-inflammatory/pro-oxidative status may play a role in increased atherothrombotic events in nilotinib treated chronic myeloid leukemia patients

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    Several reports described an increased risk of cardiovascular (CV) events, mainly atherothrombotic, in Chronic Myeloid Leukemia (CML) patients receiving nilotinib. However, the underlying mechanism remains elusive. The objective of the current cross-sectional retrospective study is to address a potential correlation between Tyrosine Kinase Inhibitors (TKIs) treatment and CV events. One hundred and 10 chronic phase CML patients in complete cytogenetic response during nilotinib or imatinib, were screened for CV events and evaluated for: traditional CV risk factors, pro/anti-inflammatory biochemical parameters and detrimental ORL1 gene polymorphisms (encoding for altered oxidized LDL receptor-1). Multivariate analysis of the whole cohort showed that the cluster of co-existing nilotinib treatment, dyslipidaemia and G allele of LOX-1 polymorphism was the only significant finding associated with CV events. Furthermore, multivariate analysis according to TKI treatment confirmed IVS4-14 G/G LOX-1 polymorphism as the strongest predictive factor for a higher incidence of CV events in nilotinib patients. Biochemical assessment showed an unbalanced pro-inflammatory cytokines network in nilotinib vs imatinib patients. Surprisingly, pre-existing traditional CV risk factors were not always predictive of CV events. We believe that in nilotinib patients an induced "inflammatory/oxidative status", together with a genetic pro-atherothrombotic predisposition, may favour the increased incidence of CV events. Prospective studies focused on this issue are ongoing

    Study of the BΛc+ΛˉcKB^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} decay

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    The decay BΛc+ΛˉcKB^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} is studied in proton-proton collisions at a center-of-mass energy of s=13\sqrt{s}=13 TeV using data corresponding to an integrated luminosity of 5 fb1\mathrm{fb}^{-1} collected by the LHCb experiment. In the Λc+K\Lambda_{c}^+ K^{-} system, the Ξc(2930)0\Xi_{c}(2930)^{0} state observed at the BaBar and Belle experiments is resolved into two narrower states, Ξc(2923)0\Xi_{c}(2923)^{0} and Ξc(2939)0\Xi_{c}(2939)^{0}, whose masses and widths are measured to be m(Ξc(2923)0)=2924.5±0.4±1.1MeV,m(Ξc(2939)0)=2938.5±0.9±2.3MeV,Γ(Ξc(2923)0)=0004.8±0.9±1.5MeV,Γ(Ξc(2939)0)=0011.0±1.9±7.5MeV, m(\Xi_{c}(2923)^{0}) = 2924.5 \pm 0.4 \pm 1.1 \,\mathrm{MeV}, \\ m(\Xi_{c}(2939)^{0}) = 2938.5 \pm 0.9 \pm 2.3 \,\mathrm{MeV}, \\ \Gamma(\Xi_{c}(2923)^{0}) = \phantom{000}4.8 \pm 0.9 \pm 1.5 \,\mathrm{MeV},\\ \Gamma(\Xi_{c}(2939)^{0}) = \phantom{00}11.0 \pm 1.9 \pm 7.5 \,\mathrm{MeV}, where the first uncertainties are statistical and the second systematic. The results are consistent with a previous LHCb measurement using a prompt Λc+K\Lambda_{c}^{+} K^{-} sample. Evidence of a new Ξc(2880)0\Xi_{c}(2880)^{0} state is found with a local significance of 3.8σ3.8\,\sigma, whose mass and width are measured to be 2881.8±3.1±8.5MeV2881.8 \pm 3.1 \pm 8.5\,\mathrm{MeV} and 12.4±5.3±5.8MeV12.4 \pm 5.3 \pm 5.8 \,\mathrm{MeV}, respectively. In addition, evidence of a new decay mode Ξc(2790)0Λc+K\Xi_{c}(2790)^{0} \to \Lambda_{c}^{+} K^{-} is found with a significance of 3.7σ3.7\,\sigma. The relative branching fraction of BΛc+ΛˉcKB^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} with respect to the BD+DKB^{-} \to D^{+} D^{-} K^{-} decay is measured to be 2.36±0.11±0.22±0.252.36 \pm 0.11 \pm 0.22 \pm 0.25, where the first uncertainty is statistical, the second systematic and the third originates from the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb public pages

    Multidifferential study of identified charged hadron distributions in ZZ-tagged jets in proton-proton collisions at s=\sqrt{s}=13 TeV

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    Jet fragmentation functions are measured for the first time in proton-proton collisions for charged pions, kaons, and protons within jets recoiling against a ZZ boson. The charged-hadron distributions are studied longitudinally and transversely to the jet direction for jets with transverse momentum 20 <pT<100< p_{\textrm{T}} < 100 GeV and in the pseudorapidity range 2.5<η<42.5 < \eta < 4. The data sample was collected with the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.64 fb1^{-1}. Triple differential distributions as a function of the hadron longitudinal momentum fraction, hadron transverse momentum, and jet transverse momentum are also measured for the first time. This helps constrain transverse-momentum-dependent fragmentation functions. Differences in the shapes and magnitudes of the measured distributions for the different hadron species provide insights into the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb public pages

    Momentum scale calibration of the LHCb spectrometer

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    For accurate determination of particle masses accurate knowledge of the momentum scale of the detectors is crucial. The procedure used to calibrate the momentum scale of the LHCb spectrometer is described and illustrated using the performance obtained with an integrated luminosity of 1.6 fb^−1 collected during 2016 in pp running. The procedure uses large samples of J/ψ → μ+ μ- and B+ → J/ψ K+ decays and leads to a relative accuracy of 3 × 10^−4 on the momentum scale

    Measurement of the ratios of branching fractions R(D)\mathcal{R}(D^{*}) and R(D0)\mathcal{R}(D^{0})

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    The ratios of branching fractions R(D)B(BˉDτνˉτ)/B(BˉDμνˉμ)\mathcal{R}(D^{*})\equiv\mathcal{B}(\bar{B}\to D^{*}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(\bar{B}\to D^{*}\mu^{-}\bar{\nu}_{\mu}) and R(D0)B(BD0τνˉτ)/B(BD0μνˉμ)\mathcal{R}(D^{0})\equiv\mathcal{B}(B^{-}\to D^{0}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(B^{-}\to D^{0}\mu^{-}\bar{\nu}_{\mu}) are measured, assuming isospin symmetry, using a sample of proton-proton collision data corresponding to 3.0 fb1{ }^{-1} of integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The tau lepton is identified in the decay mode τμντνˉμ\tau^{-}\to\mu^{-}\nu_{\tau}\bar{\nu}_{\mu}. The measured values are R(D)=0.281±0.018±0.024\mathcal{R}(D^{*})=0.281\pm0.018\pm0.024 and R(D0)=0.441±0.060±0.066\mathcal{R}(D^{0})=0.441\pm0.060\pm0.066, where the first uncertainty is statistical and the second is systematic. The correlation between these measurements is ρ=0.43\rho=-0.43. Results are consistent with the current average of these quantities and are at a combined 1.9 standard deviations from the predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb public pages

    Mario Mieli filosofo queer-freudiano: Elementi psicoanalitici di critica omosessuale

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    In questo paper si intende inquadrare i rapporti dell’attivista italiano Mario Mieli con la psicoanalisi, per definirlo come “filosofo queer-freudiano”, nonché raffinato e innovativo interprete del testo di Freud: a questo fine, bisogna innanzitutto chiarire gli elementi di queerness contenuti nei Tre saggi sulla teoria sessuale, genialmente riletti negli Elementi di critica omosessuale di Mieli. Articolerò dunque la teoria dell’ermafroditismo psichico e della bisessualità costituzionale con quella dell’omoerotismo “educastrato”, filtrata dalla lente marcusiana del freudo-marxismo che media la ricezione del Freud di Mieli. La seconda via perseguita riguarda la de-patologizzazione della schizofrenia e l’indagine sulle sofferenze sintomatiche a partire dal nesso omosessualità-suicidio, visto dalla lente psicoanalitica, in un percorso che lega i tre “casi clinici” di Mario Mieli, dell’omosessuale freudiana Dora e dell’Herculine foucaultiana.This paper examines the relationship of the italian activist Mario Mieli with psychoanalysis, in order to define him as a "queer-Freudian philosopher", as well as a refined and innovative interpreter of Freud's work: for this purpose, I first clarify the queerness elements contained in the Three Essays on Sexual Theory, brilliantly reinterpreted in Mieli's Towards A Gay Communism: Elements of a Homosexual Critique. The theory of psychic hermaphroditism and constitutional bisexuality is articulated with the “educastrated” homoeroticism, filtered through the Marcusian lens of Freudo-Marxism that mediates Mieli's reception of Freud.&nbsp; The second path I pursue concerns the de-pathologisation of schizophrenia and the investigation of the homosexuality-suicide nexus through the three "clinical cases" of Mario Mieli, the Freudian homosexual Dora, and the Foucauldian Herculine

    La relation entre le Réel et le Symbolique, du Lacan structuraliste au Lacan “immanentiste”

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    This article proposes a theoretical reconstruction of Jacques Lacan’s path from his early structuralist season to his controversial last years, marked by immanentism and a biologicist philosophy of the living. First, I investigate why Lacan is not a structuralist in the classical sense and why his notion of ‘real unconscious’ differs from both ‘trans-individual’ and ‘structured real’; so I present Lacan as not particularly indebted to Saussure and Lévi-Strauss. Detaching myself from contemporary post-structuralist readings, such as those of Zafiropoulos and Basualdo, I rather choose to ‘show’ the Lacanian Real through deconstruction, in particular through the Derridean metaphors of heliotrope and crypt. Finally, after expounding the theoretical reasons that justify the negative relationality between the Real and the Symbolic, I deny the presence of a ‘late Lacan turn’
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