One-loop effects of extra dimensions on the WW\gamma and WWZ vertices

The one-loop contribution of the excited Kaluza-Klein (KK) modes of the $SU_L(2)$ gauge group on the off-shell $WW\gamma$ and $WWZ$ vertices is calculated in the context of a pure Yang-Mills theory in five dimensions and its phenomenological implications discussed. The use of a gauge-fixing procedure for the excited KK modes that is covariant under the standard gauge transformations of the $SU_L(2)$ group is stressed. A gauge-fixing term and the Faddeev-Popov ghost sector for the KK gauge modes that are separately invariant under the standard gauge transformations of $SU_L(2)$ are presented. It is shown that the one-loop contributions of the KK modes to the off-shell $WW\gamma$ and $WWZ$ vertices are free of ultraviolet divergences and well-behaved at high energies. It is found that for a size of the fifth dimension of $R^{-1}\sim 1TeV$, the one-loop contribution of the KK modes to these vertices is about one order of magnitude lower than the corresponding standard model radiative correction. This contribution is similar to the one estimated for new gauge bosons contributions in other contexts. Tree-level effects on these vertices induced by operators of higher canonical dimension are also investigated. It is found that these effects are lower than those generated at the one-loop order by the KK gauge modes.Comment: 19 pages, 9 figures. Some typos were correcte

CHARACTERIZATION OF A COMPOSITE POLYPROPYLENE /RESIDUAL CERAMIC

Abstract Composites are materials containing two or more distinct phases with an interface, the elements interact and modifying properties of virgin material. Control interface generates the interaction between the matrix and the particles, and the mechanical properties profile according to the structure of composito1. They are often added to a polymer matrix, which typically combine the advantages of its constituent phases generating improvements in their physical and chemical properties. Mullite is an excellent candidate as a reinforcing material for its properties, however, for practical applications needs to be reinforced with zirconia. Mullite is characterized by excellent mechanical properties such as: high modulus of rupture and compressive strength both cold and hot, chemical stability, thermal stability reflected by its low coefficient of thermal expansion. At the present work we produce a composite whose polymeric matrix is polypropylene added with a residual ceramic material investment casting process, Mullite - zirconia, and PPMA as compatibilizer. Mechanical tests were performed in composites varying the percentage of ceramic and compatibilizer, SEM tests were previously performed to determine the microstructure of the ceramic materia

The Discrepancy Between tau and e+e- Spectral Functions Revisited and the Consequences for the Muon Magnetic Anomaly

We revisit the procedure for comparing the pi pi spectral function measured in tau decays to that obtained in e+e- annihilation. We re-examine the isospin-breaking corrections using new experimental and theoretical input, and find improved agreement between the tau- --> pi- pi0 nu_tau branching fraction measurement and its prediction using the isospin-breaking-corrected e+e- --> pi+pi- spectral function, though not resolving all discrepancies. We recompute the lowest order hadronic contributions to the muon g-2 using e+e- and tau data with the new corrections, and find a reduced difference between the two evaluations. The new tau-based estimate of the muon magnetic anomaly is found to be 1.9 standard deviations lower than the direct measurement.Comment: 10 pages, 6 figures, submitted to Eur. Phys. J. C; (v2): Revised version with improved and uniform treatment of tau and e+e- data with HVPTools and a few minor bug fixes; (v3): Final version accepted for publicatio

Gram-negative prosthetic joint infection: outcome of a debridement, antibiotics and implant retention approach. A large multicentre study

AbstractWe aim to evaluate the epidemiology and outcome of gram-negative prosthetic joint infection (GN-PJI) treated with debridement, antibiotics and implant retention (DAIR), identify factors predictive of failure, and determine the impact of ciprofloxacin use on prognosis. We performed a retrospective, multicentre, observational study of GN-PJI diagnosed from 2003 through to 2010 in 16 Spanish hospitals. We define failure as persistence or reappearance of the inflammatory joint signs during follow-up, leading to unplanned surgery or repeat debridement >30 days from the index surgery related death, or suppressive antimicrobial therapy. Parameters predicting failure were analysed with a Cox regression model. A total of 242 patients (33% men; median age 76 years, interquartile range (IQR) 68–81) with 242 episodes of GN-PJI were studied. The implants included 150 (62%) hip, 85 (35%) knee, five (2%) shoulder and two (1%) elbow prostheses. There were 189 (78%) acute infections. Causative microorganisms were Enterobacteriaceae in 78%, Pseudomonas spp. in 20%, and other gram-negative bacilli in 2%. Overall, 19% of isolates were ciprofloxacin resistant. DAIR was used in 174 (72%) cases, with an overall success rate of 68%, which increased to 79% after a median of 25 months' follow-up in ciprofloxacin-susceptible GN-PJIs treated with ciprofloxacin. Ciprofloxacin treatment exhibited an independent protective effect (adjusted hazard ratio (aHR) 0.23; 95% CI, 0.13–0.40; p <0.001), whereas chronic renal impairment predicted failure (aHR, 2.56; 95% CI, 1.14–5.77; p 0.0232). Our results confirm a 79% success rate in ciprofloxacin-susceptible GN-PJI treated with debridement, ciprofloxacin and implant retention. New therapeutic strategies are needed for ciprofloxacin-resistant PJI

Statistical support for the hypothesis of developmental constraint in marsupial skull evolution.

Background: In contrast to placental neonates, in which all cranial bones are ossified, marsupial young have only the bones of the oral region and the exoccipital ossified at birth, in order to facilitate suckling at an early stage of development. In this study, we investigated whether this heterochronic shift in the timing of cranial ossification constrains cranial disparity in marsupials relative to placentals. Methods: We collected three-dimensional (3D) landmark data about the crania of a wide range of extant placentals and marsupials, and from six fossil metatherians (the clade including extant marsupials and their stem relatives), using a laser scanner and a 3D digitizer. Principal components analysis and delta variance tests were used to investigate the distribution and disparity of cranial morphology between different landmark sets (optimizing either number of landmarks or number of taxa) of the whole skull and of individual developmental or functional regions (neurocranium, viscerocranium, oral region) for extant placentals and marsupials. Marsupial and placental data was also compared based on shared ecological aspects including diet, habitat, and time of peak activity. Results: We found that the extant marsupial taxa investigated here occupy a much smaller area of morphospace than the placental taxa, with a significantly (P<0.01) smaller overall variance. Inclusion of fossil taxa did not significantly increase the variance of metatherian cranial shape. Fossil forms generally plotted close to or within the realm of their extant marsupial relatives. When the disparities of cranial regions were investigated separately, significant differences between placentals and marsupials were seen for the viscerocranial and oral regions, but not for the neurocranial region. Conclusion: These results support the hypothesis of developmental constraint limiting the evolution of the marsupial skull, and further suggest that the marsupial viscerocranium as a whole, rather than just the early-ossifying oral region, is developmentally constrained

Stellar population analysis on local infrared-selected galaxies

To study the stellar population of local infrared galaxies, which contain star-forming galaxies, composite galaxies, LINERs, and Seyfert 2s. We also want to find whether infrared luminosity and spectral class have any effects on their stellar populations. The sample galaxies are selected from the main galaxy sample of SDSS-DR4 and then cross-correlated with the IRAS-PSCz catalog. We fit our spectra (stellar absorption lines and continua) using the spectral synthesis code STARLIGHT on the base of the templates of Simple Stellar Population and the spectra of star clusters.Among the 4 spectral classes, LINERs present the oldest stellar populations, and the other 3 sub-samples all present substantial young and intermediate age populations and very few old populations. The importance of young populations decreases from star-forming, composite, Seyfert 2 to LINER. As to different infrared luminosity bins, ULIGs & LIGs (log($L_{IR}/L_{\odot})\geq$11) present younger populations than starbursts and normal galaxies. However, the dominant contributors to mass are old populations in all sample galaxies. The fittings by using the spectra of star clusters with different ages and metallicities as templates also give consistent results. The dominated populations in star-forming and composite galaxies are those with metallicity $Z=0.2Z_\odot$, while LINERs and Seyfert 2s are more metal-rich. The normal galaxies are more metal-rich than the ULIGs & LIGs and starbursts for the star-forming galaxies within different infrared luminosity bins. Additionally, we also compare some synthesis results with other parameters obtained from the MPA/JHU catalog.Comment: 13 pages, 11 figures, accepted for publication by A&

The Antioxidant Potential of the Mediterranean Diet in Patients at High Cardiovascular Risk: An In-Depth Review of the PREDIMED

Cardiovascular disease (CVD) is the leading global cause of death. Diet is known to be important in the prevention of CVD. The PREDIMED trial tested a relatively low-fat diet versus a high-fat Mediterranean diet (MedDiet) for the primary prevention of CVD. The resulting reduction of the CV composite outcome resulted in a paradigm shift in CV nutrition. Though many dietary factors likely contributed to this effect, this review focuses on the influence of the MedDiet on endogenous antioxidant systems and the effect of dietary polyphenols. Subgroup analysis of the PREDIMED trial revealed increased endogenous antioxidant and decreased pro-oxidant activity in the MedDiet groups. Moreover, higher polyphenol intake was associated with lower incidence of the primary outcome, overall mortality, blood pressure, inflammatory biomarkers, onset of new-onset type 2 diabetes mellitus (T2DM), and obesity. This suggests that polyphenols likely contributed to the lower incidence of the primary event in the MedDiet groups. In this article, we summarize the potential benefits of polyphenols found in the MedDiet, specifically the PREDIMED cohort. We also discuss the need for further research to confirm and expand the findings of the PREDIMED in a non-Mediterranean population and to determine the exact mechanisms of action of polyphenols

RTP801 regulates motor cortex synaptic transmission and learning.

BACKGROUND: RTP801/REDD1 is a stress-regulated protein whose upregulation is necessary and sufficient to trigger neuronal death in in vitro and in vivo models of Parkinson's and Huntington's diseases and is up regulated in compromised neurons in human postmortem brains of both neurodegenerative disorders. Indeed, in both Parkinson's and Huntington's disease mouse models, RTP801 knockdown alleviates motor-learning deficits. RESULTS: We investigated the physiological role of RTP801 in neuronal plasticity and we found RTP801 in rat, mouse and human synapses. The absence of RTP801 enhanced excitatory synaptic transmission in both neuronal cultures and brain slices from RTP801 knock-out (KO) mice. Indeed, RTP801 KO mice showed improved motor learning, which correlated with lower spine density but increased basal filopodia and mushroom spines in the motor cortex layer V. This paralleled with higher levels of synaptosomal GluA1 and TrkB receptors in homogenates derived from KO mice motor cortex, proteins that are associated with synaptic strengthening. CONCLUSIONS: Altogether, these results indicate that RTP801 has an important role modulating neuronal plasticity and motor learning. They will help to understand its role in neurodegenerative disorders where RTP801 levels are detrimentally upregulated

Comparing six evolutionary population synthesis models through spectral synthesis on galaxies

We compare six popularly used evolutionary population synthesis (EPS) models (BC03, CB07, Ma05, GALEV, GRASIL, Vazdekis/Miles) through fitting the full optical spectra of six representative types of galaxies (star-forming and composite galaxies, Seyfert 2s, LINERs, E+A and early-type galaxies), which are taken from the Sloan Digital Sky Survey (SDSS). Throughout our paper, we use the simple stellar populations (SSPs) from each EPS model and the software STARLIGHT to do our fits. Our main results are: Using different EPS models the resulted numerical values of contributed light fractions change obviously, even though the dominant populations are consistent. The stellar population synthesis does depend on the selection of age and metallicity, while it does not depend on the stellar evolution track much. The importance of young populations decreases from star-forming, composite, Seyfert 2, LINER to early-type galaxies, and E+A galaxies lie between composite galaxies and Seyfert 2s in most cases. We conclude that different EPS models do derive different stellar populations, so that it is not reasonable to directly compare stellar populations estimated from different EPS models. To get reliable results, we should use the same EPS model for the compared samples.Comment: 13 pages, 4 figures, accepted for publication in A&

Isolation of Flow and Nonflow Correlations by Two- and Four-Particle Cumulant Measurements of Azimuthal Harmonics in sNN=\sqrt{s_{_{\rm NN}}} = 200 GeV Au+Au Collisions

A data-driven method was applied to measurements of Au+Au collisions at $\sqrt{s_{_{\rm NN}}} =$ 200 GeV made with the STAR detector at RHIC to isolate pseudorapidity distance $\Delta\eta$-dependent and $\Delta\eta$-independent correlations by using two- and four-particle azimuthal cumulant measurements. We identified a component of the correlation that is $\Delta\eta$-independent, which is likely dominated by anisotropic flow and flow fluctuations. It was also found to be independent of $\eta$ within the measured range of pseudorapidity $|\eta|<1$. The relative flow fluctuation was found to be $34\% \pm 2\% (stat.) \pm 3\% (sys.)$ for particles of transverse momentum $p_{T}$ less than $2$ GeV/$c$. The $\Delta\eta$-dependent part may be attributed to nonflow correlations, and is found to be $5\% \pm 2\% (sys.)$ relative to the flow of the measured second harmonic cumulant at $|\Delta\eta| > 0.7$