166 research outputs found
Teachers' ICT-related self-efficacy, job resources, and positive emotions: Their structural relations with autonomous motivation and work engagement
Different variables related to information and communication technologies (ICT), such as digital self-efficacy for teaching, perceived institutional support for innovation, ICT positive emotions, and satisfaction with institutional support, are key factors in the teaching-learning process. The main purpose of this study is to analyze the structural relationships of these constructs with teachers' autonomous motivation and work engagement. Data were collected from 350 in-service secondary education teachers through a self-report questionnaire and were analyzed using a two-step Structural Equation Model (SEM) approach. After testing the adequacy of the measurement model, the structural model showed that all ICT-related variables significantly predicted autonomous motivation, with 26% of explained variance. ICT-related variables and autonomous motivation explained 69% of the variance of work engagement. Emotional variables also were predicted by digital self-efficacy and institutional support. Autonomous motivation and emotional variables mediated the effects of digital self-efficacy and support for innovation on work engagement. These results shed light on the critical role of these ICT-related variables for teachers’ work motivation and engagement
Subjective age-of-acquisition norms for 7,039 Spanish words
[EN]Subjective estimations of age of acquisition (AoA)
for a large pool of Spanish words were collected from college
students in Spain. The average score for each word (based on 50
individual responses, on a scale from 1 to 11) was taken as an
AoA indicator, and normative values for a total of 7,039 single
words are provided as supplemental materials. Beyond its in trinsic value as a standalone corpus, the largest of its kind for
Spanish, the value of the database is enhanced by the fact that it
contains most of the words that are currently included in other
normative studies, allowing for a more complete characteriza tion of the lexical stimuli that are usually employed in studies
with Spanish-speaking participants. The norms are available for
downloading as supplemental materials with this article
Instructors’ teaching styles: relation with competences, self-efficacy, and commitment in pre-service teachers
Instructors’ teaching styles in higher education are an issue of major importance because these interactions affect students’ self-perceptions, involvement, and achievement. This study aimed to test a theoretical model of relations between perceived teaching styles (autonomy support, structure, and control) and competences, self-efficacy, and commitment in pre-service teachers; to assess the invariance of the model in two samples; and to analyze the mediated relations between these variables. Measures were collected from 842 Spanish pre-service teachers. As main research implications, teaching styles predicted acquired competences, competences predicted teaching self-efficacy, and self-efficacy predicted commitment to the profession. This model was equivalent in two samples of childhood and primary education pre-service teachers. Competences and self-efficacy mediated the relationships between variables. As practical implications, this study clearly shows the need for different interventions to enhance adequate instructors’ teaching styles and to foster among novice pre-service teachers the acquisition of professional competences, initial self-efficacy, and a good level of commitment to their profession
DBP rs16846876 and rs12512631 polymorphisms are associated with progression to AIDS naïve HIV-infected patients: a retrospective study
BACKGROUND: Most of the circulating Vitamin D (VitD) is transported bound to vitamin D-binding protein (DBP), and several DBP single nucleotide polymorphisms (SNPs) have been related to circulating VitD concentration and disease. In this study, we evaluated the association among DBP SNPs and AIDS progression in antiretroviral treatment (ART)-naïve-HIV-infected patients. METHODS: We performed a retrospective study in 667 patients who were classified according to their pattern of AIDS progression (183 long-term non-progressors (LTNPs), 334 moderate progressors (MPs), and 150 rapid progressors (RPs)) and 113 healthy blood donors (HIV, HCV, and HBV negative subjects). We genotyped seven DBP SNPs (rs16846876, rs12512631, rs2070741, rs2282679, rs7041, rs1155563, rs2298849) using Agena Bioscience's MassARRAY platform. The genetic association was evaluated by Generalized Linear Models adjusted by age at the moment of HIV diagnosis, gender, risk group, and VDR rs2228570 SNP. Multiple testing correction was performed by the false discovery rate (Benjamini and Hochberg procedure; q-value). RESULTS: All SNPs were in HWE (p > 0.05) and had similar genotypic frequencies for DBP SNPs in healthy-controls and HIV-infected patients. In unadjusted GLMs, we only found significant association with AIDS progression in rs16846876 and rs12512631 SNPs. In adjusted GLMs, DBP rs16846876 SNP showed significant association under the recessive inheritance model [LTNPs vs. RPs (adjusted odds ratio (aOR) = 3.53; q-value = 0.044) and LTNPs vs. MPs (aOR = 3.28; q-value = 0.030)] and codominant [LTNPs vs. RPs (aOR = 4.92; q-value = 0.030) and LTNPs vs. MPs (aOR = 3.15; q-value = 0.030)]. Also, we found DBP rs12512631 SNP showed significant association in the inheritance model dominant [LTNPs vs. RPs (aOR = 0.49; q-value = 0.031) and LTNPs vs. MPs (aOR = 0.6; q-value = 0.047)], additive [LTNPs vs. RPs (aOR = 0.61; q-value = 0.031)], overdominant [LTNPs vs. MPs (aOR = 0.55; q-value = 0.032)], and codominant [LTNPs vs. RPs (aOR = 0.52; q-value = 0.036) and LTNPs vs. MPs (aOR = 0.55; q-value = 0.032)]. Additionally, we found a significant association between DBP haplotypes (composed by rs16846876 and rs12512631) and AIDS progression (LTNPs vs RPs): DBP haplotype AC (aOR = 0.63; q-value = 0.028) and the DBP haplotype TT (aOR = 1.64; q-value = 0.028). CONCLUSIONS: DBP rs16846876 and rs12512631 SNPs are related to the patterns of clinical AIDS progression (LTNP, MP, and RP) in ART-naïve HIV-infected patients. Our findings provide new knowledge about AIDS progression that may be relevant to understanding the pathogenesis of HIV infection.This work has been (partially) funded by the RD16/0025/0019 and RD16CIII/0002/0002, projects as part of Acción Estratégica en Salud, Plan Nacional de Investigación Científica, Desarrollo e Innovación Tecnológica (2013–2016) and cofinanced by Instituto de Salud Carlos III (ISCIII-Subdirección General de Evaluación) and Fondo Europeo de Desarrollo Regional (FEDER), RETIC PT17/0015/0042, Fondo de Investigación Sanitaria (FIS) (grant number PI16/01863, PI17/01115, PI17CIII/00003), EPIICAL Project and Comunidad de Madrid B2017/BMD-3703. Programa de Investigación de la Consejería de Sanidad de la Comunidad de Madrid to JLJ. CIBER-BBN is an initiative funded by the VI National R&D&i Plan 2008–2011, Iniciativa Ingenio 2010, the Consolider Program, and CIBER Actions and financed by ISCIII with assistance from the European Regional Development Fund. This work has been supported partially by a EUROPARTNER: Strengthening and spreading international partnership activities of the Faculty of Biology and Environmental Protection for interdisciplinary research and innovation of the University of Lodz Programme: NAWA International Academic Partnership Programme. This article/publication is based upon work from COST Action CA 17140 “Cancer Nanomedicine from the Bench to the Bedside” supported by COST (European Cooperation in Science and Technology). AFR and MAJS are supported by “Instituto de Salud Carlos III” [grant number CP14/0010 and CP17CIII/00007, respectivelly]
Evaluation of a multiplex panel for the diagnosis of acute infectious diarrhea in immunocompromised hematologic patients
Introduction: diarrhea is a frequent complication in hematologic patients, being an infectious cause frequently suspected. Rapid and accurate detection of gastrointestinal pathogens is vital in immunocompromised hosts. The aim of this study was to compare routine diagnostic methods versus a multiplex polymerase chain reaction (PCR) assay for the diagnosis of infectious diarrhea in immunocompromised hematologic patients. Material and methods: we conducted a prospective observational study from March 2015 to January 2016 to compare conventional methods for the diagnosis of infectious diarrhea with FIlmArray GI Panel (BioFire-bioMérieux, France). Samples from adult immunocompromised hematologic patients with acute diarrhea were collected. In cases with discordant results, a second multiplex assay was performed (Allplex, Seegene, Korea). The result was considered positive or negative when the same result was obtained by at least two of the methods. Results: a total of 95 samples were obtained from 95 patients (median age of 52 years (46-64)). Sixty-one (64%) episodes were hospital-acquired and 34 (36%) were community-acquired diarrhea. Twenty-five (26%) patients had a positive microbiological result, being Clostridium difficile the most frequent pathogen, followed by Campylobacter spp and norovirus. The concordance between FilmArray methods was good (k = 0.79). The FilmArray GI panel showed a sensitivity of 95%, a specificity of 100% for positive results. The time required to obtain results was markedly reduced with the use of multiplex PCR methods. Conclusions: multiplex molecular panels provide a rapid and sensitive tool for the diagnosis of infectious diarrhea, thereby allowing more timely clinical decisions in immunocompromised hematologic patients
Biogeochemistry of dissolved and suspended organic matter in the Cape Vert Frontal Zone (NW Africa)
Oral communicationThe Cape Verde Frontal Zone (CVFZ) in the southern boundary of the
Canary Current Upwelling Ecosystem, is a highly dynamic area,
featuring large vertical and horizontal export fluxes of organic matter
(OM) due to the interaction of the Cape Verde Front (CVF) with the
Mauritanian upwelling. To study the interplay between transport and
biogeochemical processes driving the distribution of OM in the CVFZ,
full-depth profiles of dissolved (DOM) and suspended particulate
(POM) OM were obtained during the FLUXES I cruise in August 2017.
Distributions of surface DOM and POM and their stoichiometry were
influenced by the mesoscale variability at the frontal region, showing
significant differences north and south of the CVF and between
stations close and distant to the Mauritanian coast. The C:N
molar ratio of DOM and POM showed average vertical gradients,
increasing from 12.1 and 8.0 in surface to 15.6 and 17.0 respectively
in deeps waters, deviating from the traditional Redfield ratio. In the
meso- and bathypelagic zones, meridional and cross-shore gradients
were detected within samples belonging to the same water mass,
indicating that their properties were re-shaped by biogeochemical
processes within the CVFZ. Correlations between apparent oxygen
utilization and OM indicate that DOM+POM contributed only to
8.1% of the carbon and 17.8% of the nitrogen
mineralisation in the water column, suggesting that the local carbon
demand is mainly supported by sinking POM and N containing
compounds are mineralised to a larger extend than C containing compoundsASL
Provision of ecological infrastructures to increase pollinators and other beneficial organisms in rainfed crops in Central Spain
In sustainable intensive agriculture, the biodiversity of monoculture fields can be increased by managing the field margins to provide ecological infrastructures that serve as refuges and resources for beneficial organisms (pollinators and natural enemies). In the present work we summarize two years of field trials following the goal to increase biodiversity of beneficial fauna in a barley field in Central Spain by sowing different herbaceous mixtures in the field margins. The presence of arthropods visiting flowers on plots sown with different types of seed mixtures and unsown natural flora (control plot) was compared by visual sampling every week between April and June. The results showed that a combination of herbaceous big-size seeds was the most successful mixture emerging under our experimental conditions and achieved a higher number of visits of beneficial arthropods than the unsown natural vegetation
C2-Domain Abscisic Acid-Related Proteins Mediate the Interaction of PYR/PYL/RCAR Abscisic Acid Receptors with the Plasma Membrane and Regulate Abscisic Acid Sensitivity in Arabidopsis
Supplemental Data: http://www.plantcell.org/content/26/12/4802/suppl/DC1© 2014 American Society of Plant BiologistsMembrane-delimited abscisic acid (ABA) signal transduction plays a critical role in early ABA signaling, but the molecular mechanisms linking core signaling components to the plasma membrane are unclear. We show that transient calcium-dependent interactions of PYR/PYL ABA receptors with membranes are mediated through a 10-member family of C2-domain ABA-related (CAR) proteins in Arabidopsis thaliana. Specifically, we found that PYL4 interacted in an ABA-independent manner with CAR1 in both the plasma membrane and nucleus of plant cells. CAR1 belongs to a plant-specific gene family encoding CAR1 to CAR10 proteins, and bimolecular fluorescence complementation and coimmunoprecipitation assays showed that PYL4-CAR1 as well as other PYR/PYL-CAR pairs interacted in plant cells. The crystal structure of CAR4 was solved, which revealed that, in addition to a classical calcium-dependent lipid binding C2 domain, a specific CAR signature is likely responsible for the interaction with PYR/PYL receptors and their recruitment to phospholipid vesicles. This interaction is relevant for PYR/PYL function and ABA signaling, since different car triple mutants affected in CAR1, CAR4, CAR5, and CAR9 genes showed reduced sensitivity to ABA in seedling establishment and root growth assays. In summary, we identified PYR/PYL-interacting partners that mediate a transient Ca2+-dependent interaction with phospholipid vesicles, which affects PYR/PYL subcellular localization and positively regulates ABA signaling.We thank Joerg Kudla (University of Munster) for kindly providing plasma membrane markers. This work was supported by the Ministerio de Ciencia e Innovacion, Fondo Europeo de Desarrollo Regional, and Consejo Superior de Investigaciones Cientificas (Grants BIO2011-23446 to P.L.R and BFU2011-25384 to A. A.; fellowships to L.R., R.A., and A.C.I.-G.; BES-2009- 016569; JAE-DOC contract to M.G.-G.) as well as the Senacyt-Ifarhu (Panama) (fellowship to M.D.).Rodriguez, L.; Gonzalez Guzman, M.; Díaz, M.; Rodrigues, A.; Izquierdo Garcia, AC.; Peirats-Llobet, M.; Fernández López, MA.... (2014). C2-Domain Abscisic Acid-Related Proteins Mediate the Interaction of PYR/PYL/RCAR Abscisic Acid Receptors with the Plasma Membrane and Regulate Abscisic Acid Sensitivity in Arabidopsis. Plant Cell. 26(12):4802-4820. doi:10.1105/tpc.114.129973S48024820261
Recuperación laboral en empleados fuera del trabajo: una revisión paraguas de revisiones sistemáticas y meta-análisis
Work is a fundamental condition of human life, but it can become dysfunctional because in certain situations it may lead to undesirable and harmful consequences. In this context, recovery from work (recovery) is conceived as a counterpoint to the straining processes to which the employee is exposed in the workplace. Among the different recovery strategies adopted by workers, those carried out outside working hours are especially relevant. Scientific interest in this filed is evidenced by the publication of numerous systematic reviews in recent years. The aim of this study is to shed light and provide evidence on the results of the systematic reviews carried out to date. Thus, it was conducted an umbrella review of systematic reviews and meta-analyses on work recovery outside working hours. To this end, a systematic search of potentially relevant documents was implemented in six databases, both thematic and multidisciplinary. Eight systematic reviews and meta-analyses that met the established inclusion criteria were retrieved. The content analysis of the selected papers enabled us to identify different approaches to the study of external work recovery: (a) time period; (b) work characteristics; (c) recovery experiences; (d) recovery activities; (e) processes that hinder effective recovery; and (f) variables proxy to the recovery process. Likewise, the main considered substantive occupational and psychosocial variables were systematized. It is discussed the scarce attention paid in the reviewed studies to possible cultural differences that could potentially influence the recovery process. Furthermore, no research has made special reference to the COVID-19 pandemic in work recovery, nor to the potential influence of new emerging work realities such as teleworking or co-working.El trabajo es una condición fundamental de la vida humana pero puede resultar disfuncional por acarrear consecuencias indeseadas y nefastas en determinadas situaciones. En este contexto se entiende la recuperación del trabajo (recovery) como contrapunto a los procesos de tensión a los que se ve sometida la persona en su puesto de trabajo. Dentro de las diferentes estrategias que los trabajadores ponen en marcha para recuperarse, resultan de especial relevancia las llevadas a cabo fuera de su horario laboral. El interés científico en esta materia queda patente en la publicación de numerosas revisiones sistemáticas en los últimos años. El objetivo de este estudio es clarificar y aportar evidencia sobre los resultados de las revisiones sistemáticas realizadas hasta la fecha. Así, se realizó una revisión paraguas de revisiones sistemáticas y metaanálisis sobre la recuperación laboral fuera del horario de trabajo. Para ello se llevó a cabo una búsqueda sistemática de documentos potencialmente relevantes en seis bases de datos, tanto temáticas como multidisciplinares. Se recuperaron ocho revisiones sistemáticas y metanálisis que cumplieron los criterios de inclusión establecidos. El análisis de contenido de los trabajos seleccionados permitió identificar diversas perspectivas o encuadres en el estudio de la recuperación laboral externa: (a) el período temporal; (b) las características del trabajo; (c) las experiencias de recuperación; (d) las actividades de recuperación; (e) los procesos que impiden que la recuperación sea efectiva; y (f) las variables cercanas al proceso de recuperación. Asimismo, se sistematizaron las principales variables sustantivas de naturaleza laboral y psicosocial consideradas en los diversos trabajos. Se discute la escasa atención prestada en los estudios revisados a las posibles diferencias culturales que podrían afectar al proceso de recuperación. Además, ninguna investigación hace mención especial a la pandemia por la COVID-19 en la recuperación laboral, ni tampoco a la potencial influencia de las nuevas realidades laborales en auge como el teletrabajo o los espacios virtuales compartidos (co-working)
Veterinaria es Calidad
En una Universidad tan grande y antigua como la UCM donde las dinámicas de funcionamiento llevan décadas implantadas, la Cultura de la Calidad no ha sido entendida y acogida por una parte del colectivo universitario, que ve en ella una imposición, moda o, cuanto menos, la ruptura de una dinámica existente. Romper esta inercia depende de que todo el colectivo reconozca la necesidad y utilidad de estos métodos que permiten seguir avanzando adaptándose a una sociedad en continua evolución. Nuestro objetivo era que la comunidad universitaria del centro fuera consciente de la existencia de un sistema de calidad que era, en gran parte, responsable de las mejoras de las que todos disfrutamos
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