10 research outputs found
De cómo en el fragor de la batalla el entrometido dijo “hablemos” y por qué rara razón los contendientes, brazo en alto, detuvieron el gesto y el arma para escucharle/ No es cine para Hombres
This text focus on various cinematographic works documentaries, and films principally, but also musicals, sociological studies, photographic montage, philosophical works, theater, and news –to highlight the masculine subjectivity that inhabits them–. Talking like a man today, calling oneself a man, and acting like a man, is different today than calling oneself a man, and acting as such, two, three or more decades ago. This text, this author, claim the current world is emptied of masculinityEl presente texto se sumerge en diversas obras cinematográficas, de ficción y documentales, principalmente, pero también musicales, sociológicas, fotográficas, filosóficas, teatrales, mediáticas..., para poner de manifiesto la subjetividad –masculina– que habita en ellas. El decir del hombre hoy; el decirse y actuar como hombre hoy es diferente al decirse hombre y actuar como tal hace dos, tres o más décadas. El resultado, dice el texto, dice su autor, es un mundo vaciado de sustancia masculina
¿Cómo escribir poesía después de "GH2"?: El Yoyas como crítico cultural en verso
This article proposes an approach to the phenomenon of trash culture from the perspective of aesthetics and cultural criticism. From a humoristic perspective, the author connects two trash genres that are apparently unrelated: television and poetry. The object of the study is the television personality and writer Carlos Navarro Merino, whose work is discussed as a case of a double link, both aesthetic and social in nature
Estética del relato posmoderno
El presente trabajo de investigación se propone ofrecer una definición conceptual y tipológica del paradigma del relato breve literario a lo largo de la época posmoderna. Partiendo de una perspectiva comparatista, la base de esta investigación consiste en un conjunto de oposiciones en relación con el modelo moderno. A partir de ellas tesis toma como caso central el movimiento posmoderno norteamericano y traza una serie de vínculos teóricos y conceptuales, principalmente con las literaturas del ámbito hispánico y, en menor medida, con casos de estudio procedentes de las letras inglesas e italianas. En la línea de las investigaciones que abordan la época posmoderna desde una posición conclusiva, este trabajo abarca un arco temporal que va desde la emergencia del movimiento posmoderno a finales de los años sesenta hasta su reformulación en el la corriente avant-pop a mediados de los noventa.
Palabras clave: posmodernismo, comparatismo, relato, fin de siglo, estudios culturales, tipologíaThis research aims to provide a conceptual and typological definition of the paradigm of short story along the postmodern era. From a comparative perspective, this research is based on a set of oppositions in relation to the modern model. Using theAmerican postmodern movement as a central case, it draws a series of theoretical and conceptual links, mainly to Hispanic literatures and to a lesser extent to English and Italian authors. In the line of research that addresses the postmodern era from a conclusive position, this work covers a time span ranging from the emergence of the postmodern movement in the late sixties to its final reformulation in the avant-pop current of the mid-nineties.
Keywords: postmodernism, comparative literature, short story, end of the century, cultural studies, tipolog
Vecindarios productivos sostenibles a partir de la acupuntura rural. Vivienda rural progresiva en el municipio de Caparrapí, Cundinamarca
Artículo de GradoA través del aprendizaje basado en problemas, se identifica el desequilibrio en las cadenas de comercialización agrícolas en Caparrapí, Cundinamarca. El diseño concurrente permite consolidar una estrategia territorial a partir de la acupuntura rural y la construcción de vecindarios productivos sostenibles en el municipio para mejorar sus procesos de producción y comercialización, y se consolida la vivienda rural como el equipamiento principal en las fincas productivas que redefine la forma de habitar la ruralidad.INTRODUCCIÓN
1. METODOLOGÍA
2. RESULTADOS
3. DISCUSIÓN
4. CONCLUSIONES
AGRADECIMIENTOS
REFERENCIAS
ANEXOSPregradoArquitect
Marrow versus peripheral blood for geno-identical allogeneic stem cell transplantation in acute myelocytic leukemia: Influence of dose and stem cell source shows better outcome with rich marrow
Several studies have compared bone marrow (BM) and peripheral blood (PB) as stem cell sources in patients receiving allografts, but the cell doses infused have not been considered, especially for BM. Using the ALWP/EBMT registry, we retrospectively studied 881 adult patients with acute myelocytic leukemia (AML), who received a non-T-depleted allogeneic BM (n = 515) or mobilized PB (n = 366) standard transplant, in first remission (CR1), from an HLA-identical sibling, over a 5-year period from January 1994. The BM cell dose ranged from 0.17 to 29 × 108/kg with a median of 2.7 × 108/kg. The PB cell dose ranged from 0.02 to 77 × 10 8/kg with a median of 9.3 × 108/kg. The median dose for patients receiving BM (2.7 × 108/kg) gave the greatest discrimination. In multivariate analyses, high-dose BM compared to PB was associated with lower transplant-related mortality (RR = 0.61; 95% CI, 0.39-0.98; P = .04), better leukemia-free survival (RR = 0.65; 95% CI, 0.46-0.91; P = .013), and better overall survival (RR = 0.64; 95% CI, 0.44-0. 92; P = .016). The present study in patients with AML receiving allografts in first remission indicates a better outcome with BM as compared to PB, when the dose of BM infused is rich. © 2003 by The American Society of Hematology
Marrow versus peripheral blood for geno-identical allogeneic stem cell transplantation in acute myelocytic leukemia: Influence of dose and stem cell source shows better outcome with rich marrow
PubMed ID: 12829583Several studies have compared bone marrow (BM) and peripheral blood (PB) as stem cell sources in patients receiving allografts, but the cell doses infused have not been considered, especially for BM. Using the ALWP/EBMT registry, we retrospectively studied 881 adult patients with acute myelocytic leukemia (AML), who received a non-T-depleted allogeneic BM (n = 515) or mobilized PB (n = 366) standard transplant, in first remission (CR1), from an HLA-identical sibling, over a 5-year period from January 1994. The BM cell dose ranged from 0.17 to 29 × 10 8 /kg with a median of 2.7 × 10 8 /kg. The PB cell dose ranged from 0.02 to 77 × 10 8 /kg with a median of 9.3 × 10 8 /kg. The median dose for patients receiving BM (2.7 × 10 8 /kg) gave the greatest discrimination. In multivariate analyses, high-dose BM compared to PB was associated with lower transplant-related mortality (RR = 0.61; 95% CI, 0.39-0.98; P = .04), better leukemia-free survival (RR = 0.65; 95% CI, 0.46-0.91; P = .013), and better overall survival (RR = 0.64; 95% CI, 0.44-0. 92; P = .016). The present study in patients with AML receiving allografts in first remission indicates a better outcome with BM as compared to PB, when the dose of BM infused is rich. © 2003 by The American Society of Hematology
Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
Objective:To develop and validate a prediction model (STOMA score) for 1-year stoma-free survival in patients with rectal cancer (RC) with anastomotic leakage (AL).Background:AL after RC resection often results in a permanent stoma.Methods:This international retrospective cohort study (TENTACLE-Rectum) encompassed 216 participating centres and included patients who developed AL after RC surgery between 2014 and 2018. Clinically relevant predictors for 1-year stoma-free survival were included in uni and multivariable logistic regression models. The STOMA score was developed and internally validated in a cohort of patients operated between 2014 and 2017, with subsequent temporal validation in a 2018 cohort. The discriminative power and calibration of the models' performance were evaluated.Results:This study included 2499 patients with AL, 1954 in the development cohort and 545 in the validation cohort. Baseline characteristics were comparable. One-year stoma-free survival was 45.0% in the development cohort and 43.7% in the validation cohort. The following predictors were included in the STOMA score: sex, age, American Society of Anestesiologist classification, body mass index, clinical M-disease, neoadjuvant therapy, abdominal and transanal approach, primary defunctioning stoma, multivisceral resection, clinical setting in which AL was diagnosed, postoperative day of AL diagnosis, abdominal contamination, anastomotic defect circumference, bowel wall ischemia, anastomotic fistula, retraction, and reactivation leakage. The STOMA score showed good discrimination and calibration (c-index: 0.71, 95% CI: 0.66-0.76).Conclusions:The STOMA score consists of 18 clinically relevant factors and estimates the individual risk for 1-year stoma-free survival in patients with AL after RC surgery, which may improve patient counseling and give guidance when analyzing the efficacy of different treatment strategies in future studies
Stoma-free survival after anastomotic leak following rectal cancer resection: worldwide cohort of 2470 patients
Background: The optimal treatment of anastomotic leak after rectal cancer resection is unclear. This worldwide cohort study aimed to provide an overview of four treatment strategies applied. Methods: Patients from 216 centres and 45 countries with anastomotic leak after rectal cancer resection between 2014 and 2018 were included. Treatment was categorized as salvage surgery, faecal diversion with passive or active (vacuum) drainage, and no primary/secondary faecal diversion. The primary outcome was 1-year stoma-free survival. In addition, passive and active drainage were compared using propensity score matching (2: 1). Results: Of 2470 evaluable patients, 388 (16.0 per cent) underwent salvage surgery, 1524 (62.0 per cent) passive drainage, 278 (11.0 per cent) active drainage, and 280 (11.0 per cent) had no faecal diversion. One-year stoma-free survival rates were 13.7, 48.3, 48.2, and 65.4 per cent respectively. Propensity score matching resulted in 556 patients with passive and 278 with active drainage. There was no statistically significant difference between these groups in 1-year stoma-free survival (OR 0.95, 95 per cent c.i. 0.66 to 1.33), with a risk difference of -1.1 (95 per cent c.i. -9.0 to 7.0) per cent. After active drainage, more patients required secondary salvage surgery (OR 2.32, 1.49 to 3.59), prolonged hospital admission (an additional 6 (95 per cent c.i. 2 to 10) days), and ICU admission (OR 1.41, 1.02 to 1.94). Mean duration of leak healing did not differ significantly (an additional 12 (-28 to 52) days). Conclusion: Primary salvage surgery or omission of faecal diversion likely correspond to the most severe and least severe leaks respectively. In patients with diverted leaks, stoma-free survival did not differ statistically between passive and active drainage, although the increased risk of secondary salvage surgery and ICU admission suggests residual confounding
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)