Studying the laws of software evolution in a long-lived FLOSS project

ome free, open-source software projects have been around for quite a long time, the longest living ones dating from the early 1980s. For some of them, detailed information about their evolution is available in source code management systems tracking all their code changes for periods of more than 15 years. This paper examines in detail the evolution of one of such projects, glibc, with the main aim of understanding how it evolved and how it matched Lehman's laws of software evolution. As a result, we have developed a methodology for studying the evolution of such long-lived projects based on the information in their source code management repository, described in detail several aspects of the history of glibc, including some activity and size metrics, and found how some of the laws of software evolution may not hold in this cas

Blended transdiagnostic group CBT for emotional disorders: A feasibility trial protocol

Introduction: Emotional disorders (anxiety and depressive disorders) are a relevant public health concern associated with high prevalence, high costs, and important disability. Therefore, research priorities include designing and testing cost-effective interventions to reach everyone in need. Internet-delivered interventions for emotional disorders are effective and can help to disseminate and implement evidence-based treatments. However, although these treatments are generally effective, not all patients benefit from this treatment format equally. Blended treatments are a new form of intervention that combines the strengths of face-to-face and Internet approaches. Nevertheless, research on blended interventions has focused primarily on individual therapy, and less attention has been paid to the potential of using this format in group psychotherapy. This study aims to analyze the feasibility of blended transdiagnostic group CBT for emotional disorders. The current article describes the study protocol for this trial. Method and analysis: A one-armed pilot trial will be conducted. Participants will be 30 adults suffering from DSM-5 anxiety and/or depressive disorders. The treatment consists of a blended transdiagnostic group intervention delivered during a period of 24 weeks. Groups of 6 to 10 patients will attend a total of eight 2-hour, face-to-face sessions, alternated with the use of an online platform where they will find the contents of the treatment protocol. The intervention has four core components: present-focused awareness, cognitive flexibility, identification and modification of behavioral and cognitive patterns of emotional avoidance, and interoceptive and situational exposure. These components are delivered in 16 modules. Assessments will be performed at baseline, during the treatment, at post-treatment, and at 3-month follow-up. Clinical and treatment acceptability outcomes will be included. Quantitative and qualitative data (participants’ views about blended group psychotherapy) will be analyzed. Ethics and dissemination: The trial has received ethical approval from the Ethics Committee of Universitat Jaume I (September 2019) and will be conducted in accordance with the study protocol, the Declaration of Helsinki, and good clinical practice. The results of this study will be disseminated by presentation at conferences and will be submitted for publication in a peer-reviewed journal. Trial registration: ClinicalTrials.gov Identifier: NCT04008576. Registered 05 July 2019, https://clinicaltrials.gov/ct2/show/NCT0400857

Blended transdiagnostic group CBT for emotional disorders: a feasibility trial protocol

Emotional disorders (anxiety and depressive disorders) are a relevant public health concern associated with high prevalence, high costs, and important disability. Therefore, research priorities include designing and testing cost-effective interventions to reach everyone in need. Internet-delivered interventions for emotional disorders are effective and can help to disseminate and implement evidence-based treatments. However, although these treatments are generally effective, not all patients benefit from this treatment format equally. Blended treatments are a new form of intervention that combines the strengths of face-to-face and Internet approaches. Nevertheless, research on blended interventions has focused primarily on individual therapy, and less attention has been paid to the potential of using this format in group psychotherapy. This study aims to analyze the feasibility of blended transdiagnostic group CBT for emotional disorders. The current article describes the study protocol for this trial

Three-dimensional spatial distribution of synapses in the neocortex: A dual-beam electron microscopy study

In the cerebral cortex, most synapses are found in the neuropil, but relatively little is known about their 3-dimensional organization. Using an automated dual-beam electron microscope that combines focused ion beam milling and scanning electron microscopy, we have been able to obtain 10 three-dimensional samples with an average volume of 180 µm(3) from the neuropil of layer III of the young rat somatosensory cortex (hindlimb representation). We have used specific software tools to fully reconstruct 1695 synaptic junctions present in these samples and to accurately quantify the number of synapses per unit volume. These tools also allowed us to determine synapse position and to analyze their spatial distribution using spatial statistical methods. Our results indicate that the distribution of synaptic junctions in the neuropil is nearly random, only constrained by the fact that synapses cannot overlap in space. A theoretical model based on random sequential absorption, which closely reproduces the actual distribution of synapses, is also presented

Diagnóstico pré-natal de síndrome de Noonan: relato de caso: Prenatal diagnosis Noonan syndrome: a case report

A síndrome de Noonan caracteriza-se por se manifestar como uma doença do tipo genético na qual será apresentada uma tríade composta por cardiopatia congênita, baixa estatura e diferentes características faciais. Sua incidência em todo o mundo é de 1 caso em 1.000 a 2.500 recém-nascidos. Os sinais que ocorrem no pré-natal geralmente são inespecíficos e podem incluir aumento da transluscência nucal, higroma cístico e ascite. Quando houver suspeita, uma ultrassonografia pré-natal deve ser realizada nas semanas 12, 14 e 20 de gestação. No entanto, o diagnóstico pré-natal principalmente na síndrome de Noonan é feito através de vilosidades coriônicas ou líquido amniótico, quando há maior suspeita clínica, deve-se realizar estudo molecular. O presente caso é de uma paciente de 19 anos, primeira gestação, com histórico de hipotireoidismo e diabetes gestacional em tratamento. Ela vai ao centro de saúde para controle devido a uma gravidez de 36 semanas pela data da última menstruação, onde foi realizada uma ultrassonografia, que está dentro dos parâmetros normais, uma cesariana é realizada na semana 38 devido ao histórico patológico, onde recém-nascido com fácies é evidenciado sugestivo de síndrome de Noonan, que no pré e pós-natal não foi adequadamente diagnosticada, por ser um caso muito raro e complicado, apresentou um diagnóstico clínico difícil. Diagnosticar uma Síndrome de Noonan no pré-natal é útil no momento do parto, pois melhora a sobrevida do recém-nascido e ajuda a agir de forma interdisciplinar, devido às complicações que a própria síndrome acarreta. O diagnóstico pré-natal na Síndrome de Noonan é complicado devido à sua baixa prevalência, além das características ultrassonográficas indeterminadas que existem

Quid: observatorio de medios

Informe organizado en cinco capítulos. En "El sistema de comunicación en Guadalajara" se incluyen trabajos sobre la transformación de algunos medios de comunicación, nuevos medios de comunicación en línea, periodismo religioso, la falta de institucionalidad en el Sistema Jalisciense de Radio y Televisión, y el sistema legal de radiodifusión y telecomunicaciones. En "Libertad de expresión en Jalisco", se presentan trabajos sobre la inseguridad laboral en los medios de comunicación, el desinformado cuarto de guerra del gobernador Aristóteles Sandoval, y sobre los periodistas escritores. En el apartado "Derecho a la información en Jalisco", se presenta un trabajo sobre la mucha administración y dosificada transparencia del Instituto de Trasparencia e Información Pública de Jalisco. El quinto apartado es una semblanza sobre “Rudy”, Rodolfo Rosales López, fotoperiodista tapatío. En el último apartado, “La investigación del observatorio de medios”, se presenta un trabajo sobre la cobertura en temas de medio ambiente y cambio climático en el periódico El Informador.ITESO, A.C

Journal of Roleplaying Studies and STEAM (JRPSSTEAM) Vol. 2 [2023], Issue 1.

Journal of Roleplaying Studies and STEAM (JRPSSTEAM) Vol. 2 [2023], Issue 1

Q ITESO: Análisis Crítico de Medios

En esta séptima entrega de Q ITESO: Análisis Crítico de Medios se examina un 2014 colmado de acontecimientos sobre la reconfiguración de los medios de Jalisco y del país, y sus relaciones con el estado, los empresarios y el público. Destaca la aprobación de la Ley Federal de Telecomunicaciones y Radiocomunicación y los nuevos equilibrios de poder que esto supone. También, se analizan las alianzas de algunos diarios nacionales y del estado con medios extranjeros, para compensar algunas carencias y ampliar su oferta editorial e informativa. Otras cuestiones no menos relevantes tienen que ver con la libertad de expresión y la inseguridad laboral en la que viven muchos trabajadores de los medios de comunicación jaliscienses, sobre todo los impresos, y el caso emblemático del llamado “cuarto de guerra” al servicio del gobernador del estado, Aristóteles Sandoval, para espiar -y en ocasiones hasta coaccionar- a directivos y reporteros de medios para atenuar la crítica al gobierno. El derecho a la información, la transparencia, la situación de los nuevos medios en línea, los periodistas que publican libros, el cambio climático y los periodistas que ya no están con nosotros merecen también una mirada atenta en este informe.ITESO, A.C

Breve historia de la Facultad de Odontología

La Facultad de Odontología se fundó el 27 de diciembre de 1963 e inició actividades el 3 de marzo de 1964. Años más tarde, el 19 de mayo de 1986, el H. Consejo Universitario aprobó su cambio de escuela a Facultad de Odontología. La conmemoración de 55 años de esta Facultad y 40 años de hermandad con las Universidades de Meikai y Asahi, se constituye un momento oportuno para manifestar el testimonio de cuanto han realizado hombres y mujeres que han dejado huella en esta institución

Bronchoscopist's perception of the quality of the single-use bronchoscope (Ambu aScope4™) in selected bronchoscopies: a multicenter study in 21 Spanish pulmonology services

Background: The disposable bronchoscope is an excellent alternative to face the problem of SARS-CoV-2 and other cross infections, but the bronchoscopist’s perception of its quality has not been evaluated. Methods: To evaluate the quality of the Ambu-aScope4 disposable bronchoscope, we carried out a cross-sectional study in 21 Spanish pulmonology services. We use a standardized questionnaire completed by the bronchoscopists at the end of each bronchoscopy. The variables were described with absolute and relative frequencies, measures of cen‑ tral tendency and dispersion depending on their nature. The existence of learning curves was evaluated by CUSUM analysis. Results: The most frequent indications in 300 included bronchoscopies was bronchial aspiration in 69.3% and the median duration of these was 9.1 min. The route of entry was nasal in 47.2% and oral in 34.1%. The average score for ease of use, image, and aspiration quality was 80/100. All the planned techniques were performed in 94.9% and the bronchoscopist was satisfed in 96.6% of the bronchoscopies. They highlighted the portability and immediacy of the aScope4TM to start the procedure in 99.3%, the possibility of taking and storing images in 99.3%. The CUSUM analysis showed average scores>70/100 from the frst procedure and from the 9th procedure more than 80% of the scores exceeded the 80/100 score