9 research outputs found
Comparative 3D QSAR study on β1-, β2-, and β3-adrenoceptor agonists
- Author
- AE Weber
- AV Gavai
- B Hu
- B Hu
- B Hu
- B Hu
- B Waldeck
- C Weyer
- CJ deSouza
- CL Waller
- CP Kordik
- DD Feng
- DE Uehling
- E Danforth Jr
- EM Naylor
- EM Naylor
- ER Parmee
- ER Parmee
- FW Sum
- G Stuti
- H Harada
- H Waterbeemd van De
- HO Ok
- J Gasteiger
- J Himms-Hagen
- J Wess
- JA Bikker
- JD Bloom
- JG Baker
- JR Arch
- JRS Arch
- K Mizuno
- K Mizuno
- KE Furse
- LL Brockunier
- M Kontoyianni
- M Sawa
- M Sawa
- MA Ashwell
- P Gyanendra
- P Prathipati
- P. Senthil Kumar
- Prasad V. Bharatam
- PS Kumar
- RD Cramer
- RJ Lefkowitz
- RJ Mathvink
- RL Dow
- S Wold
- SK Kashaw
- T Biftu
- T Schoneberg
- TI Oprea
- Tripos Inc
- WN Washburn
- WN Washburn
- Y Igawa
- Y Nakajima
- Publication venue
- SP Birkhäuser Verlag Boston
- Publication date
- 01/01/2009
- Field of study
A quantitative structureâactivity relationship study of tryptamine-based derivatives of β1-, β2-, and β3-adrenoceptor agonists was conducted using comparative molecular field analysis (CoMFA). Correlation coefficients (cross-validated r2) of 0.578, 0.595, and 0.558 were obtained for the three subtypes, respectively, in three different CoMFA models. All three CoMFA models have different steric and electrostatic contributions, implying different requirements inside the binding cavity. The CoMFA coefficient contour plots of the three models and comparisons among these plots provide clues regarding the main chemical features responsible for the biological activity variations and also result in predictions which correlate very well with the observed biological activity. Based on the analysis, a summary regeospecific description of the requirements for improving β-adrenoceptor subtype selectivity is given
Rising Power Clusters and the Challenges of Local and Global Standards
- Author
- A Chan
- A Fleury
- A GuarĂn
- A Malmberg
- A Marshall
- A Mezzadri
- A Mezzadri
- A PeĹa
- A Posthuma
- A Sachdeva
- A Smith
- AK Basu
- C Brandi
- C Ketels
- CF Sabel
- CK-C Chan
- CK-C Chan
- CK-C Chan
- D Boucher
- D McCormick
- D Messner
- D OâRourke
- F Khan
- FW Mayer
- G Ceglie
- G Gereffi
- G Gereffi
- G Neve De
- G Neve De
- H Bathelt
- H Schmitz
- H Schmitz
- H Schmitz
- H Schmitz
- HT Dinh
- IR Gordon
- J Henderson
- J Henderson
- J Henderson
- J Humphrey
- J Humphrey
- J Meyer-Stamer
- J Neilson
- JA Puppim de Oliviera
- JA Puppim de Oliviera
- K Nadvi
- K Nadvi
- K Nadvi
- K Nadvi
- K Nadvi
- K Nadvi
- K Nadvi
- K Nadvi
- Khalid Nadvi
- L Bazan
- L Kennedy
- L Navas-Aleman
- M Almeida
- M Amengual
- M Battaglia
- M Blowfield
- M Hess
- M Holmstrom
- M Porter
- M Tewari
- M Tewari
- MD Parrilli
- MJ Enright
- MJ Piore
- N Egels-ZandĂŠn
- N Khara
- N Pun
- N Pun
- NL Sum
- NM Coe
- P Knorringa
- P Knorringa
- P Lund-Thomsen
- P Lund-Thomsen
- P Lund-Thomsen
- P Lund-Thomsen
- P Lund-Thomsen
- P Lund-Thomsen
- Peter Knorringa
- Planning Commission Government of India
- R Gomes
- R Kaplinsky
- R Kaplinsky
- R Martin
- R Pires
- R Quadros
- R Rabellotti
- RM Locke
- RR Sinkovics
- S Breslin
- S Henson
- S Laha
- S Ponte
- S Ponte
- S Zhu
- SP Cohen
- SV Coslovsky
- T Bartley
- T Bartley
- T Donaldson
- W Cragg
- W Ge
- X Yu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Utility of scalp-recorded ictal electroencephalograms in childhood epilepsy with complex partial seizures
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Allgemeine Prinzipien und sp2âsp3-Transformation
- Author
- A Hosomi
- A Jefferson
- A Marfat
- CA Henrick
- CS Kraihanzel
- DG Batt
- DJ Faulkner
- E Wenkert
- E Winterfeldt
- EJ Corey
- F Bohlmann
- F Sato
- FE Ziegler
- FL Harris
- FW Sum
- G Kresze
- G Kresze
- GB Bennett
- H Naka-Mura
- HH Hansen
- HJ Liu
- HU Reissig
- I Fleming
- J Reucroft
- J Szmuszkovicz
- J. SAUER
- LD Boardman
- LE Overman
- LE Overman
- LE Overman
- M Alderdice
- M Julia
- M Kukushima
- M. BEDNARSKI
- ME Jung
- ME Wright
- P Chamberlain
- PE Sonnet
- R Amouroux
- R Baker
- R Grigg
- RB Miller
- RP Lutz
- S Danishefsky
- S Danishefsky
- S Danishefsky
- S Danishefsky
- S Danishefsky
- S Ranganathan
- SM Weinreb
- SM Weinreb
- SM Weinreb
- W Granitzer
- W Oppolzer
- W Oppolzer
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1988
- Field of study
mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold
- Author
- A Bartelt
- A Efeyan
- A Kauffmann
- A Kharitonenkov
- A Pfeifer
- B Cannon
- B Cannon
- B Emanuelli
- B Vandanmagsar
- BS Carvalho
- C Hu
- CF Bentzinger
- CH Vaughan
- CJ Potter
- CS Patlak
- D Richard
- DD Sarbassov
- DG Nicholls
- DO Foster
- DP Blondin
- DP Blondin
- DP Blondin
- E Hondares
- E Vander Haar
- FG Tafesse
- FW Sum
- I Ben-Sahra
- I Ben-Sahra
- IL Cameron
- J Eguchi
- J Karar
- J Klein
- J Nedergaard
- J van den Hoff
- J van den Hoff
- JB Young
- JFP BerbĂŠe
- JM Olsen
- JW Park
- K Abnous
- K Birsoy
- K Inoki
- K Martens
- K Romanino
- KA Virtanen
- KY Lee
- L Sidossis
- M Chondronikola
- M Klingenspor
- M Laplante
- MA Moura
- MN Brito
- NH Kawashita
- P Polak
- P Puigserver
- P Shende
- PL Lee
- R Hernandez
- R Taguchi
- RA Irizarry
- RC Gentleman
- S Enerbäck
- S Heber
- S Keipert
- S Sengupta
- S-H Ro
- SF Morrison
- SL Menard
- SM LabbĂŠ
- SS Bird
- T Barnd
- T Yamada
- T Yoshida
- TR Peterson
- V Albert
- V Golozoubova
- V Ouellet
- V Ouellet
- VG Tusher
- VL Bessi
- W Aherne
- WD van Marken Lichtenbelt
- WT Festuccia
- WT Festuccia
- WT Festuccia
- X Xiang
- Y Sancak
- Z Pang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Performance of the CMS Hadron Calorimeter with Cosmic Ray Muons and LHC Beam Data
- Author
- Abadjiev K
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abelev B
- Acosta D
- Acosta JG
- Acosta MV
- Actis O
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adolphi R
- Adzic P
- Afaq MA
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Ahmad M
- Ahmad WH
- Ahmed I
- Ahmed W
- Ahuja S
- Aisa D
- Aisa S
- Akchurin N
- Akgun B
- Akgun U
- Akimenko S
- Akin IV
- Alagoz E
- Alampi G
- Albajar C
- Albayrak EA
- Alberdi J
- Albergo S
- Albert E
- Albrow M
- Alexander J
- Alidra M
- Aliev T
- Allfrey P
- Almeida N
- Altenhofer G
- Altsybeev I
- Alver B
- Alverson G
- Alves GA
- Amaglobeli N
- Amapane N
- Ambroglini F
- Amsler C
- Anagnostou G
- Ananthan B
- Anastassov A
- Andelin D
- Anderson M
- Andrea J
- Andreev V
- Andreev Y
- Anghel IM
- Anguelov T
- Anisimov A
- Antillon E
- Antipov P
- Antonelli L
- Anttila E
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Apresyan A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Arnold B
- Arora S
- Artamonov A
- Asaadi J
- Asghar MI
- Ashby S
- Askew A
- Atac M
- Atramentov O
- Auffray E
- Aurisano A
- Autermann C
- Avery P
- Avetisyan A
- Avila C
- Awan MIM
- Ayan AS
- Ayhan A
- Azhgirey I
- Aziz T
- Azzi P
- Azzurri P
- Baarmand MM
- Babb J
- Babucci E
- Baccaro S
- Bacchetta N
- Bacchi W
- Bachtis M
- Baden D
- Badgett W
- Baechler J
- Baer H
- Baesso P
- Baffioni S
- Bagby L
- Bagliesi G
- Bahk SY
- Bailleux D
- Baillon P
- Bainbridge R
- Bakhshiansohi H
- Bakirci MN
- Bakken JA
- Balazs M
- Baldin B
- Ball AH
- Ball G
- Ballin J
- Bally SL
- Ban Y
- Bandurin D
- Banerjee S
- Banerjee S
- Banicz K
- Bansal S
- Banzuzi K
- Barashko V
- Barbagli G
- Barberis E
- Barbone L
- Barcala JM
- Barcellan L
- Bard R
- Bargassa P
- Baringer P
- Barnes VE
- Barnett BA
- Barney D
- Barone L
- Bartalini P
- Bartoloni A
- Bartz E
- Basegmez S
- Battilana C
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- Bauerdick LAT
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- Bazterra VE
- Bean A
- Beauceron S
- Beaudette F
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- Bechtel F
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- Bedoya CF
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- Bejar JC
- Belforte S
- Beliy N
- Bell KW
- Bellan P
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- Bellato M
- Bellinger JN
- Belotelov I
- Benaglia A
- Bencze G
- Bendavid J
- Bender W
- Benedetti D
- Benelli G
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- Besson A
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- Bhat PC
- Bhatnagar V
- Bhattacharya S
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- Blaha J
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- Blumenfeld B
- Blyweert S
- Boccali T
- Bocci A
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- Bodek A
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- CMS Collaboration
- Cockerill DJA
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- Publication venue
- Publication date
- 01/01/1
- Field of study
The CMS Hadron Calorimeter in the barrel, endcap and forward regions is fully
commissioned. Cosmic ray data were taken with and without magnetic field at the
surface hall and after installation in the experimental hall, hundred meters
underground. Various measurements were also performed during the few days of
beam in the LHC in September 2008. Calibration parameters were extracted, and
the energy response of the HCAL determined from test beam data has been
checked
Performance of the CMS hadron calorimeter with cosmic ray muons and LHC beam data
- Author
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- Inst. of Physics
- Publication date
- 01/01/1
- Field of study
This is the Pre-print version of the Article. The official published version of the Paper can be accessed from the link below - Copyright @ 2010 IOPThe CMS Hadron Calorimeter in the barrel, endcap and forward regions is fully commissioned. Cosmic ray data were taken with and without magnetic field at the surface hall and after installation in the experimental hall, hundred meters underground. Various measurements were also performed during the few days of beam in the LHC in September 2008. Calibration parameters were extracted, and the energy response of the HCAL determined from test beam data has been checked.This work is supported by FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ,
and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS
(Colombia); MSES (Croatia); RPF (Cyprus); Academy of Sciences and NICPB (Estonia);
Academy of Finland, ME, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); PAEC (Pakistan); SCSR (Poland); FCT (Portugal); JINR
(Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MST and MAE (Russia); MSTDS (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA)
Materiality - The future of Swedish municipal sustainability reporting? : An exploratory & qualitative case study on municipal materiality analysis of Agenda-2030 key figures.
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- Publication venue
- LinnĂŠuniversitetet, Institutionen fĂśr ekonomistyrning och logistik (ELO)
- Publication date
- 01/01/1
- Field of study
Studien visar att materialitetsanalys till viss del redan sker i kommunal verksamhet när de upprättar hüllbarhetsredovisning. Däremot är denna i münga fall mycket ostrukturerad och i vissa fall reflekterar inte kommunerna Üver att de prioriterar information. Materialitetsanalysen som utfÜrdes av kommunerna visade dels att Agenda 2030-nyckeltalen som är ämnade att användas och implementeras i sin helhet i münga fall är svürhanterlig med grund i kommunernas självstyre och unika sammanhang. Vidare visade studien att materialitetsanalysen kan vara användbar fÜr att hitta de nyckeltal bland Agenda 2030-nyckeltalen som faktiskt är användbara fÜr en specifik kommun. Detta eftersom vad som är att anse som materiellt eller inte till stÜrsta del verkar vara helt beroende pü varje enskild kommuns egen uppfattning. Vad som statuerar ett materiellt nyckeltal är alltsü mycket beroende pü varje enskild kommun. Däremot är det viktigt fÜr kommunerna att nyckeltalet faktiskt gür att arbeta med. Huruvida kommunen tidigare haft fram- eller motgüngar med nyckeltalet tycks inte vara av nügon stÜrre vikt. Matrisen lüter ocksü kommunerna reflektera kring och analysera nyckeltalen vilket kan utgÜra ett gott komplement till nyckeltalen i hüllbarhetsredovisningen. Kommunerna är bekanta med Agenda 2030 och vikten av att implementera denna i sin hüllbarhetsredovisning. Materialitetsanalysen tillüter detta att ske systematiskt och är användbart fÜr att ta hänsyn till varje kommuns fÜrutsättningar. Pü sü vis närmar sig kommunerna materiella hüllbarhetsredovisningar med substans snarare än generella kopior av varandra med intetsägande nyckeltal. Detta innebär ocksü att legitimitetsgapet mot samhället minskas. Explicit tryck i form av lagar fÜr att driva pü kommunal hüllbarhetsredovisning medfÜr risker. Detta kan bestü av att information tas med fÜr att tillgodose ett lagkrav och inte fÜr att det är materiellt. Materialitetsanalysen har en plats i kommunal hüllbarhetsredovisning, detta är mÜjligt utan att tvinga dit den med lagar. Genom att belysa användbarheten och det värde en strukturerad analys av nyckeltal eller annan information ger hüllbarhetsredovisningen kan ocksü en norm bildas som främjar kvalitet framfÜr inställsamhet.The study shows that materiality analysis to some extent already takes place in municipal activities when they prepare sustainability reports. However, in many cases this is unstructured and in some cases the municipalities do not reflect on the fact that they prioritize information. The materiality analysis carried out by the municipalities showed that the Agenda 2030 key figures that are intended to be used and implemented in their entirety are in many cases difficult to handle and not suitable as a national standard based on the municipalities' autonomy and unique contexts. Furthermore, the study showed that the materiality analysis can be useful for finding the key figures among the Agenda 2030 key figures that are useful for a specific municipality. This is because what is to be regarded as material or not largely seems to be dependent on each individual municipality's own perception. What constitutes a material key figure is thus highly dependent on each individual municipality. On the other hand, it is important for the municipalities that the key figure is operational. Whether the municipality has previously had successes or setbacks with the key figure does not seem to be of any major importance to if it is to be regarded material or not.The matrix also allows the municipalities to reflect on and analyze the key figures, which can be a good complement to the key figures in the sustainability report. The municipalities are familiar with Agenda 2030 and the importance of implementing this in their sustainability report. The materiality analysis allows this to take place systematically and is useful for considering the conditions of each municipality. In this way, the municipalities approach material sustainability reports with substance rather than general copies of each other with bland key figures. Doing this will help the municipal to reduce the legitimacy gap. Explicit pressure in the form of laws to push for municipal sustainability reporting entails risks. This may consist of information being disclosed to satisfy a legal requirement and not because it is material. The materiality analysis has a place in municipal sustainability reporting, and it can take this without being forced to do so by laws. By highlighting the usefulness and the value that a structured analysis of key figures or other information provides in the sustainability report, a norm can also be formed that promotes quality over conformity in municipal sustainability reporting
Performance of the CMS hadron calorimeter with cosmic ray muons and LHC beam data
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- Publication venue
- Inst. of Physics
- Publication date
- 01/01/1
- Field of study
This is the Pre-print version of the Article. The official published version of the Paper can be accessed from the link below - Copyright @ 2010 IOPThe CMS Hadron Calorimeter in the barrel, endcap and forward regions is fully commissioned. Cosmic ray data were taken with and without magnetic field at the surface hall and after installation in the experimental hall, hundred meters underground. Various measurements were also performed during the few days of beam in the LHC in September 2008. Calibration parameters were extracted, and the energy response of the HCAL determined from test beam data has been checked.This work is supported by FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ,
and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS
(Colombia); MSES (Croatia); RPF (Cyprus); Academy of Sciences and NICPB (Estonia);
Academy of Finland, ME, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); PAEC (Pakistan); SCSR (Poland); FCT (Portugal); JINR
(Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MST and MAE (Russia); MSTDS (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA)