474 research outputs found

    O que pensam os adolescentes das histórias que lêem?

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    Pesquisa feita com alunos do primeiro grau em São Paulo revela que o entendimento daquilo que lêem, sempre por obrigação escolar, é muito abaixo daquilo que se espera. Como ajudar a resolver a questão? A pesquisa aponta caminhos.A survey carried out among elementary school students in São Paulo reveals that understanding what is read, always for school work, is below the expected. How to help solve this matter? The survey reveals a few ways

    KLAXON EM MARSELHA

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    A autora apresenta a revista francesa La Criée, editada cm Marselhaentre 1921 e 1923, e que foi citada na revista modernista brasileiraKlaxon. La Criée, por sua vez, cita Klaxon, reproduz um artigode Sérgio Milliet sobre Henri Mugnier e uma tradução de "0 discobolo", de Guilherme de Almeida.Além de mostrar as relações entre as duas revistas, a autora pretende dar subsídios para fixar-se objetivamente a divulgação deKlaxon na França e para se compreender até onde chegava a participação vanguardista dos colaboradores de Klaxon

    Cardiovascular Risk Factors in End-Stage Renal Disease Patients: The Impact of Conventional Dialysis versus Online-Hemodiafiltration

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    End-stage renal disease (ESRD) patients present high incidence of cardiovascular (CV) events, which are the most common causes of death in these patients. The occurrence of CV events appears as a consequence of the high prevalence of traditional and non-traditional CV risk factors. Online-hemodiafiltration (OL-HDF) was introduced as a better alternative to conventional dialysis, as it was proposed to be more biocompatible, to increase dialysis efficacy, to reduce the inflammatory response to treatment and to improve patient’s quality of life, contributing to reduce CV and all-cause mortality risk in ESRD. However, data in literature, comparing the effect of OL-HDF with conventional dialysis for clinical CV outcome and all-cause mortality, yielded controversy about those benefits of OL-HFD over standard hemodialysis. A review of the traditional CV risk factors (e.g., arterial hypertension, diabetes mellitus, dyslipidemia, obesity, smoking and advanced age), non-traditional risk factors (e.g., anemia, oxidative stress, hyperphosphatemia, endothelial dysfunction, left ventricular hypertrophy, insulin resistance, high levels of lipoprotein(a) and inflammation) and potential renocardiovascular biomarkers, in the setting of ESRD, is presented. The impact of conventional hemodialysis and OL-HDF on CV risk factors and on the outcome of ESRD patients is also addressed

    Rio de Janeiro como Cidade Inteligente

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    O Centro de Operações Rio (COR) é uma sala de controle que reúne representantes das agências e secretarias da Prefeitura do Rio de Janeiro e monitora as imagens das câmeras espalhadas pela cidade. Além da gestão do cotidiano da cidade, o centro teve papel relevante na organização para os megaeventos. Neste contexto, a presente pesquisa explora a influência do COR nos novos processos de mediatização da experiência urbana, sobretudo no que tange as mobilidades. Como metodologia, lançamos mão de entrevistas realizadas com pessoas que tiveram papéis decisivos na criação e operação do COR, bem como de uma bibliografia que trata dos temas da mediação, da mediatização e das cidades inteligentes. Além disso, o conceito de cibermobilidades nos ajuda a evidenciar o entrelaçamento das dimensões físicas, virtuais e comunicacionais das mobilidades. A pesquisa aponta que o centro alterou as dinâmicas de mobilidades da cidade, sobretudo por sua integração com apps de navegação e trânsito e sua constante presença nos veículos de comunicação e mídias sociais

    Effect of built environment factors on pedestrian safety in Portuguese urban areas

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    This paper identifies and analyzes variables that influence pedestrian safety based on the definition of models of pedestrian crash frequency for urban areas in Portugal. It considers three groups of explanatory variables, namely: (i) built environment; (ii) pedestrian infrastructure, and (iii) road infrastructure, as well as exposure variables combining pedestrian and vehicular traffic volumes. Data on the 16 variables considered were gathered from locations in the counties of Braga and Guimarães. The inclusion of pedestrian infrastructure variables in studies of this type is an innovation that allows for measuring the impacts of the dimensions recommended for this type of infrastructure and assessing the implementation of policies to support the mobility of vulnerable users, especially pedestrians. Examples of such variables are unobstructed space for pedestrian mobility and the recommendable distance separating regulated crossings. Zero-Truncated Negative Binomial Regression Models (ZTNB) and Generalized Estimation Equations (GEE) are used to develop crash prediction models. Results show that in addition to the variables identified in similar studies such as carriageway width, other statistically significant variables like longitudinal slope and distance between crosswalks have a negative influence on pedestrian safety. On-street parking places, one-way streets, and the existence of raised medians have an opposite contribution to safety.This research was funded by FUNDAÇÃO PARA A CIÊNCIA E A TECNOLOGIA (FCT), in the scope of the projects AnPeB—Analysis of pedestrian behavior based on simulated urban environments and its incorporation in risk modelling (PTDC/ECM-TRA/3568/2014) and Studies to promote sustainable and safe urban mobility (Agreement FCT/CAPES), in the frame of the strategic project (UIDB/04029/2020) and doctoral scholarships (SFRH/BD/131638/2017) and (SFRH/BD/138728/2018)

    Biodegradable polymers on cementitious materials

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    PTDC/EPH-PAT/4684/2014 IF/01054/2014/CP1224/CT0005 UID/QUI/50006/2019 UID/Multi/04378/2019 POCI-01-0145-FEDER-007728Nowadays the sustainability and safety requirements of structures inspire the study of new self healing materials and preventive repair methods on cementitious elements. To achieve this undertaking, this research replaces widely employed synthetic polymers by biodegradable ones as consolidants and water-repellents, and assesses the protection and consolidation effect of biopolymers (obtained by using waste biomass of mixed microbial cultures from polyhydroxyalkanoates production processes) as eco-friendly healing agents by analysing the water absorption of two kind of materials. The first group of samples are cement mortar specimens whose external surface has been treated with biopolymer products and subsequently evaluated by water drop absorption test. The second group of samples are cement mortar specimens formulated with biopolymer products included in its mixing water and later the waterproofing efficiency is analysed by capillary water absorption tests. The water absorption behaviour of both kind of samples shows a potential improvement of cementitious elements durability, since water absorption results have decreased for treated samples in comparison with untreated ones.authorsversionpublishe

    Neutrophil activation and resistance to recombinant human erythropoietin therapy in Hemodialysis Patients

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    The aim of this work was to evaluate the neutrophil activation state in chronic kidney disease (CKD) patients under hemodialysis, and its linkage with resistance to recombinant human erythropoietin (rhEPO) therapy. Methods: We studied 63 CKD patients under hemodialysis and rhEPO treatment (32 responders and 31 non-responders to rhEPO therapy). In 20 of the CKD patients (10 responders and 10 non-responders to rhEPO therapy), blood samples were also collected immediately after dialysis. Twenty-six healthy volunteers were included in a control group. Hemoglobin levels, total and differential leukocyte counts, and circulating levels of C-reactive protein (CRP), elastase and lactoferrin were measured in all patients and controls. Results: Compared with controls, CKD patients presented with significantly higher CRP, neutrophil and elastase levels. When we compared the 2 groups of patients, we found that non-responders presented statistically significantly higher elastase plasma levels. A positive significant correlation was found between elastase levels and weekly rhEPO dose and CRP serum levels. After the hemodialysis procedure, a statistically significant rise in elastase, lactoferrin and, elastase/neutrophil and lactoferrin/neutrophil ratios were found. Conclusions: Our data show that CKD patients under hemodialysis present higher elastase levels (particularly in non-responding patients), which could be related to the rise in neutrophils, and to be part of the enhanced inflammatory process found in these patient
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