10,726 research outputs found
Post-Lie Algebras, Factorization Theorems and Isospectral-Flows
In these notes we review and further explore the Lie enveloping algebra of a
post-Lie algebra. From a Hopf algebra point of view, one of the central
results, which will be recalled in detail, is the existence of a second Hopf
algebra structure. By comparing group-like elements in suitable completions of
these two Hopf algebras, we derive a particular map which we dub post-Lie
Magnus expansion. These results are then considered in the case of
Semenov-Tian-Shansky's double Lie algebra, where a post-Lie algebra is defined
in terms of solutions of modified classical Yang-Baxter equation. In this
context, we prove a factorization theorem for group-like elements. An explicit
exponential solution of the corresponding Lie bracket flow is presented, which
is based on the aforementioned post-Lie Magnus expansion.Comment: 49 pages, no-figures, review articl
Nonequilibrium Dynamics in Noncommutative Spacetime
We study the effects of spacetime noncommutativity on the nonequilibrium
dynamics of particles in a thermal bath. We show that the noncommutative
thermal bath does not suffer from any further IR/UV mixing problem in the sense
that all the finite-temperature non-planar quantities are free from infrared
singularities. We also point out that the combined effect of finite temperature
and noncommutative geometry has a distinct effect on the nonequilibrium
dynamics of particles propagating in a thermal bath: depending on the momentum
of the mode of concern, noncommutative geometry may switch on or switch off
their decay and thermalization. This momentum dependent alternation of the
decay and thermalization rates could have significant impacts on the
nonequilibrium phenomena in the early universe at which spacetime
noncommutativity may be present. Our results suggest a re-examination of some
of the important processes in the early universe such as reheating after
inflation, baryogenesis and the freeze-out of superheavy dark matter
candidates.Comment: 24 pages, 2 figure
Impact of chronic obstructive pulmonary disease (COPD) in the Asia-Pacific region: the EPIC Asia population-based survey.
published_or_final_versio
Nucleation mechanism for the direct graphite-to-diamond phase transition
Graphite and diamond have comparable free energies, yet forming diamond from
graphite is far from easy. In the absence of a catalyst, pressures that are
significantly higher than the equilibrium coexistence pressures are required to
induce the graphite-to-diamond transition. Furthermore, the formation of the
metastable hexagonal polymorph of diamond instead of the more stable cubic
diamond is favored at lower temperatures. The concerted mechanism suggested in
previous theoretical studies cannot explain these phenomena. Using an ab initio
quality neural-network potential we performed a large-scale study of the
graphite-to-diamond transition assuming that it occurs via nucleation. The
nucleation mechanism accounts for the observed phenomenology and reveals its
microscopic origins. We demonstrated that the large lattice distortions that
accompany the formation of the diamond nuclei inhibit the phase transition at
low pressure and direct it towards the hexagonal diamond phase at higher
pressure. The nucleation mechanism proposed in this work is an important step
towards a better understanding of structural transformations in a wide range of
complex systems such as amorphous carbon and carbon nanomaterials
The FMOS-COSMOS survey of star-forming galaxies at z~1.6. IV: Excitation state and chemical enrichment of the interstellar medium
We investigate the physical conditions of ionized gas in high-z star-forming
galaxies using diagnostic diagrams based on the rest-frame optical emission
lines. The sample consists of 701 galaxies with an Ha detection at , from the FMOS-COSMOS survey, that represent the normal
star-forming population over the stellar mass range with those at being
well sampled. We confirm an offset of the average location of star-forming
galaxies in the BPT diagram ([OIII]/Hb vs. [NII]/Ha), primarily towards higher
[OIII]/Hb, compared with local galaxies. Based on the [SII] ratio, we measure
an electron density (), that is higher
than that of local galaxies. Based on comparisons to theoretical models, we
argue that changes in emission-line ratios, including the offset in the BPT
diagram, are caused by a higher ionization parameter both at fixed stellar mass
and at fixed metallicity with additional contributions from a higher gas
density and possibly a hardening of the ionizing radiation field. Ionization
due to AGNs is ruled out as assessed with Chandra. As a consequence, we revisit
the mass-metallicity relation using [NII]/Ha and a new calibration including
[NII]/[SII] as recently introduced by Dopita et al. Consistent with our
previous results, the most massive galaxies ()
are fully enriched, while those at lower masses have metallicities lower than
local galaxies. Finally, we demonstrate that the stellar masses, metallicities
and star formation rates of the FMOS sample are well fit with a
physically-motivated model for the chemical evolution of star-forming galaxies.Comment: 38 pages; Accepted for publication in Ap
Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent Apoptosis, but are insensitive to direct activation with exogenous fas ligand
Introduction
Cholangiocarcinoma is a rare malignancy of the biliary tract, the incidence of which is rising, but the pathogenesis of which remains uncertain. No common genetic defects have been described but it is accepted that chronic inflammation is an important contributing factor. We have shown that primary human cholangiocyte and hepatocyte survival is tightly regulated via co-operative interactions between two tumour necrosis family (TNF) receptor family members; CD40 and Fas (CD95). Functional deficiency of CD154, the ligand for CD40, leads to a failure of clearance of biliary tract infections and a predisposition to cholangiocarcinoma implying a direct link between TNF receptor-mediated apoptosis and the development of cholangiocarcinoma.
Aims
To determine whether malignant cholangiocytes display defects in CD40 mediated apoptosis. By comparing CD40 and Fas-mediated apoptosis and intracellular signalling in primary human cholangiocytes and three cholangiocyte cell lines.
Results
Primary cholangiocytes and cholangiocyte cell lines were relatively insensitive to direct Fas-mediated killing with exogenous FasL when compared with Jurkat cells, which readily underwent Fas-mediated apoptosis, but were extremely sensitive to CD154 stimulation. The sensitivity of cells to CD40 activation was similar in magnitude in both primary and malignant cells and was STAT-3 and AP-1 dependent in both.
Conclusions
1) Both primary and malignant cholangiocytes are relatively resistant to Fas–mediated killing but show exquisite sensitivity to CD154, suggesting that the CD40 pathway is intact and fully functional in both primary and malignant cholangiocytes 2) The relative insensitivity of cholangiocytes to Fas activation demonstrates the importance of CD40 augmentation of Fas dependent death in these cells. Agonistic therapies which target CD40 and associated intracellular signalling pathways may be effective in promoting apoptosis of malignant cholangiocytes
Instantons and Condensate
We argue that the is similar to .Comment: 6 pages, 1 fig., 1 tab., RevTeX to be use
Some Applications of Thermal Field Theory to Quark-Gluon Plasma
The lecture provides a brief introduction of thermal field theory within
imaginary time formalism, the Hard Thermal Loop perturbation theory and some of
its application to the physics of the quark-gluon plasma, possibly created in
relativistic heavy ion collisions.Comment: 17 pages, 12 figures : Lectures given in "Workshop on Hadron Physics"
during March 7-17, 2005, Puri, Indi
Molecular excitation in the Interstellar Medium: recent advances in collisional, radiative and chemical processes
We review the different excitation processes in the interstellar mediumComment: Accepted in Chem. Re
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