Zebrafish as animal model for aquaculture nutrition research.

The aquaculture industry continues to promote the diversification of ingredients used in aquafeed in order to achieve a more sustainable aquaculture production system. The evaluation of large numbers of diets in aquaculture species is costly and requires time-consuming trials in some species. In contrast, zebrafish (Danio rerio) can solve these drawbacks as an experimental model, and represents an ideal organism to carry out preliminary evaluation of diets. In addition, zebrafish has a sequenced genome allowing the efficient utilization of new technologies, such as RNA-sequencing and genotyping platforms to study the molecular mechanisms that underlie the organism's response to nutrients. Also, biotechnological tools like transgenic lines with fluorescently labeled neutrophils that allow the evaluation of the immune response in vivo, are readily available in this species. Thus, zebrafish provides an attractive platform for testing many ingredients to select those with the highest potential of success in aquaculture. In this perspective article aspects related to diet evaluation in which zebrafish can make important contributions to nutritional genomics and nutritional immunity are discussed

The confined hydrogen atom with a moving nucleus

We study the hydrogen atom confined to a spherical box with impenetrable walls but, unlike earlier pedagogical articles on the subject, we assume that the nucleus also moves. We obtain the ground-state energy approximately by means of first--order perturbation theory and by a more accurate variational approach. We show that it is greater than the one for the case in which the nucleus is clamped at the center of the box. Present approach resembles the well-known treatment of the helium atom with clamped nucleus

Stock mechanics: a general theory and method of energy conservation with applications on DJIA

A new method, based on the original theory of conservation of sum of kinetic and potential energy defined for prices is proposed and applied on Dow Jones Industrials Average (DJIA). The general trends averaged over months or years gave a roughly conserved total energy, with three different potential energies, i.e. positive definite quadratic, negative definite quadratic and linear potential energy for exponential rises (and falls), sinusoidal oscillations and parabolic trajectories, respectively. Corresponding expressions for force (impact) are also given. Keywords:Comment: 14 pages, 3 figures, scehudled for IJMPC 17/ issue

Morfología polínica de la subfamilia rutoideae (Rutaceae) en Andalucía

Se estudia la morfol ogía pol ínica de Ruta montana , R. cha l e pens i s , R. angusti foli a , Haplophyllum linifolium , Dictamnus a lbus y D. hispanic us tanto al microscopio óptico como al el ectrónico de barrido . Se descr iben cuatro tipos polínicos diferentes en base al tamaño , grosor de la exina y ornamentaciónThe pollen of Ruta montana , R. chal epensis, R. angus t i f o l ia, Ha plophyllum l i ni folium, Dictamnus albus and D. hispani c us are studied by light and scanning electron microscope. Using the size , ex i ne' s thickness and ornamentation, fdur types of pol l en grains are recogni ze

A model of maxilla resection to test new hybrid implants:macroporous titanium and tissue engineering elements

Maxillary bone loss in commonly found in humans, due to bone ageing, tooth loos, periodontal disease and, more severely, to trauma, radiotherapy and tumor resection. Masillofacial reconstructive surgery is a still unmet clinical demand, available therapies include grafting of autologous or heterologous bone tissue and/or the implantation of metallic plates, buy these treatments are still unable to resume form and function. The emrgence of 3D-printing technology applied to metal alloys now allows the manufacturing of customized, patient-tailored prosthetic implants. However, poor bone quiality at the implant site due to ageing or disease still hamper proper osseointegration. By combining Electron Beam Melting metal sintering and tissue engineering, we are developing hybrid maxillofacial implants, wher a metal framework of Ti6Al4V alloy confers both and appropiaate shape and mechanical stabilty, while stem cells and osteogenic molecules stimulate bone growth into the metal framework, thus pormoting osseointegration. We hereby present the in vitro work driving to the development of our hybrid maxillofacial prostheses, as well as the setting up of an in vivo model of complete maxilla full resection, created in order to test the prostheses in a preclinical studyUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

How does water get to the clouds? Building explanations about state changes in Early Childhood Education

Este estudio de caso en un aula de tercero de educación infantil (23 niñas y niños, 5-6 años, y su maestra) examina la evolución de las explicaciones del alumnado sobre cambios de estado líquido-gas a lo largo de cinco meses de un proyecto escolar de ciencias. Para construir sus explicaciones movilizaron tanto su conocimiento cotidiano como el conocimiento científico escolar. Desarrollaron la capacidad de aplicar el vocabulario científico para explicar sus experiencias cotidianas. El fenómeno de evaporación fue identificado y explicado por el alumnado con mayor facilidad que el fenómeno de condensación. Proponemos una rúbrica para analizar la construcción de explicaciones. Las implicaciones educativas sugieren que es recomendable iniciar el estudio de los cambios de estado en educación infantil, ya que el alumnado reconoce estos fenómenos, los relaciona con su conocimiento cotidiano y es capaz de construir explicaciones que pueden servir de base para desarrollar otras más complejas.This case study in a third year Early Childhood Education (ECE) classroom (23 children, 5-6 years old) and their teacher examines the evolution in children's explanations about state changes between liquid and gas in the course of a school science project that lasted for five months. They mobilized both their everyday and school science knowledge in order to build explanations. They developed the ability to apply scientific vocabulary to account for their everyday experiences. Children identified the phenomenon of evaporation more easily than the condensation. We propose a rubric for the analysis of the construction of explanations. Educational implications suggest that state changes should be addressed from ECE, since children are able to identify these phenomena, relate them to their everyday knowledge and build explanations about them, which may serve as a basis for developing more complex ones

Tycho Brahe's supernova: light from centuries past

The light curve of SN 1572 is described in the terms used nowadays to characterize SNeIa. By assembling the records of the observations done in 1572--74 and evaluating their uncertainties, it is possible to recover the light curve and the color evolution of this supernova. It is found that, within the SNe Ia family, the event should have been a SNIa with a normal rate of decline, its stretch factor being {\it s} $\sim$ 0.9. Visual light curve near maximum, late--time decline and the color evolution sustain this conclusion. After correcting for extinction, the luminosity of this supernova is found to be M$_{V}$ $=$ --19.58 --5 log (D/3.5 kpc) $\pm$ 0.42.Comment: 28 pages, 3 figures, 3 tables. submitted to ApJ (Main Journal

Aplicaciones del uso de la técnica de espectroscopía de reflectancia difusa en química forense para la carcterización de autenticidad de los sellos de correos de España

Dentro del área de las Ciencias Forenses, la Documentoscopia es una de sus secciones más atractivas. Tan atractiva como es la Filatelia, el coleccionismo de efectos postales, en el mundo moderno. La Espectroscopía de Reflectancia Difusa, debido a tener como principal característica el ser una técnica no destructiva y de fácil manejo, puede ser una herramienta de gran valor para el estudio de la autenticidad de piezas filatélicas. En este trabajo, presentamos un análisis cualitativo de varios sellos antiguos españoles procedentes de diferentes emisiones desde el reinado de Isabel II hasta Alfonso XIII, profundizando en la Serie del Gobierno Provisional de 1870 -caracterizada por la profusión de los variados colores encontrados a lo largo de los 13 valores que componen la serie completa-, e incluso estudiando efectos auténticos frente a otros ejemplares falsos indubitadosIn the area of forensic sciences, the questioned document examination is one of its most attractive sections. As attractive as philately, the collecting of postal effects, in the modern world. Diffuse reflectance spectroscopy, due to have as main characteristic being a technique of non-destructive and easy to use, can be a tool of great value to the study of the philatelic pieces authenticity. In this work, using Diffuse Reflectance Spectroscopy, we present qualitative analysis of several early Spanish stamps issued from different emissions since the reign of Queen Isabel II to King Alfonso XIII, deepening over the series of the Provisional Government issued in 1870 - characterized by the profusion of variations of the colors found among the 13 values that compose the complete series-, and even studying authentic effects against other counterfeit recognized as fake copies