Trauma Exposure Among Women in the Pacific Rim

Purpose Healthcare professionals who provide services in the immediate or long‐term aftermath of traumatic events need to understand the nature and frequency of traumatic events in the lives of women. However, research on trauma exposure in women has only recently begun to assess events other than intimate partner and sexual violence and has not supported direct statistical comparison of cross‐national and cross‐cultural data. The purpose of this descriptive, correlational study was to describe and compare trauma exposure prevalence and type in community‐based samples of women in the United States, Colombia, and Hong Kong. Design Women were recruited through posted notices at community health sites, snowball sampling, and online advertisements (N = 576). The Life Stressor Checklist‐Revised (total score range 0 to 30) was used to determine the type and prevalence of trauma exposure. Data were collected by native language members of the research team. Methods Descriptive statistics were used to summarize demographic characteristics and trauma exposure for the total sample and each community‐based sample (location). Between‐location differences were tested using Fisher\u27s exact tests for categorical measures and general linear models with pairwise a posteriori least squares t‐test for continuous measures. Responses to open‐ended questions were translated and categorized. Findings Over 99% of women in the total sample reported at least one traumatic life event. The mean number of traumatic life events per participant was 7, ranging from 0 to 24. Although there was consistency in the most commonly reported trauma exposures across locations, the rates of specific events often differed. Conclusions Historical, political, geographic, and cultural factors may explain differences in trauma exposure among women in the four locations studied. Clinical Relevance This study offers relevant knowledge for providers in diverse locations who provide services to women who have experienced traumatic events and provides evidence for the need for future research to further enhance knowledge of trauma exposure among women, and on the effects of trauma in women\u27s lives

Desarrollo del pensamiento lógico-matemático en estudiantes de primer grado mediante el uso de las tic

En la actualidad han tomado gran auge la aplicación de estrategias didácticas, que incorporan las Tecnologías de la Información y la Comunicación más conocidas como las TIC en el proceso de enseñanza-aprendizaje en las diversas áreas del conocimiento, y las matemáticas no son la excepción, con lo cual se permite el fortalecimiento del pensamiento lógico-matemático en los estudiantes y es fundamental empezar desde el primer grado de la básica primaria. Teniendo en cuenta que, en la actualidad, las TIC hacen parte de la vida diaria de la gran mayoría de los estudiantes, se logró concluir que tomando ventaja del interés que las TIC despiertan hoy en día en los estudiantes no importando su edad, este interés se puede canalizar para fortalecer el pensamiento lógico-matemático desde muy temprana edad, ya que las TIC permiten que el proceso de enseñanza-aprendizaje sea más ameno y participativo, además se puede continuar con este proceso, fuera del aula de clases

Synthesis of the O-linked hexasaccharide containing b-D-Galp-(1→2)- D-Galf in Trypanosoma cruzi mucins. Differences on sialylation by trans-sialidase of the two constituent hexasaccharides

The hexasaccharide b-D-Galp-(1?2)-[b-D-Galp-(1?3)]-b-D-Galp-(1?6)-[b-D-Galp(1?2)-b-D-Galf(1?4)]- D-GlcNAc (10) and its b-D-Galf-(1?2)-b-D-Galf containing isomer (7) are the largest carbohydrates in mucins of some strains of Trypanosoma cruzi. The terminal b-D-Galp units are sites of sialylation by the parasite trans-sialidase. Hexasaccharide 10 was chemically synthesized for the first time by a [3+3] nitrilium based convergent approach, using the trichloroacetimidate method of glycosylation. The 1 H NMR spectrum of its alditol was identical to the spectrum of the product released by b-elimination from the parasite mucin. The trans-sialylation reaction studied on the benzyl glycoside of 10 showed two monosialylated products whose relative abundance changed with time. On the other hand, only one product was produced by sialylation of the benzyl glycoside of 7. A preparative synthesis of the latter and spectroscopic analysis of the product unequivocally established the sialylation site at the less hindered (1?3)-linked galactopyranose.Fil: Agusti, Rosalia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; ArgentinaFil: Giorgi, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; ArgentinaFil: Mendoza, Veronica Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; ArgentinaFil: Kashiwagi, Gustavo Adolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; ArgentinaFil: Muchnik, Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; ArgentinaFil: Gallo, Carola. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentin

Diurnal variation of precipitable water vapor over Central and South America

Annual and seasonal diurnal precipitable water vapor (PWV) variations over Central and South America are analyzed for the period 2007–2013. PWV values were obtained from Global Navigation Satellite Systems (GNSS) observations of sixty-nine GNSS tracking stations. Histograms by climate categories show that PWV values for temperate, polar and cold dry climate have a positive skewed distribution and for tropical climates (except for monsoon subtype) show a negative skewed distribution. The diurnal PWV and surface temperatures (T) anomaly datasets are analyzed by using principal components analysis (PCA). The first two modes represent more than 90% of the PWV variability. The first PCA mode of PWV variability shows a maximum amplitude value in the late afternoon few hours later than the respective values for surface temperature (T), therefore the temperature and the surface conditions (to yield evaporation) could be the main agents producing this variability; PWV variability in inland stations are mainly represented by this mode. The second mode of PWV variability shows a maximum amplitude at midnight, a possible explanation of this behavior is the effect of the sea/valley breeze. The coastal and valley stations are affected by this mode in most cases. Finally, the “undefined” stations, surrounded by several water bodies, are mainly affected by the second mode with negative eigenvectors. In the seasonal analysis, both the undefined and valley stations constitute the main cases that show a sea or valley breeze only during some seasons, while the rest of the year they present a behavior according to their temperature and the surface conditions. As a result, the PCA proves to be a useful numerical tool to represent the main sub-daily PWV variabilities.Fil: Meza, Amalia Margarita. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Laboratorio Maggia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Mendoza, Luciano Pedro Oscar. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Laboratorio Maggia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Natali, Maria Paula. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Laboratorio Maggia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Bianchi, Clara Eugenia. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Laboratorio Maggia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Fernandez, Laura Isabel. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Laboratorio Maggia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentin

Association of -1082 interleukin-10 gene polymorphism in Peruvian adults with chronic periodontitis

Objectives: The aim of this study was to assess association of the -1082 IL-10 gene polymorphism with chronic periodontitis CP in a Peruvian population. Study Design: Samples of venous blood and DNA were obtained from 106 Peruvian subjects: a) 53 periodontally healthy; and b) 53 with CP. The association of the -1082 IL-10 promoter sequences was assessed by Polymerase chain reaction-restriction fragment length polymorfism (PCR-RFLP). Student's t test were used to assess the clinical parameters, as well as the x2 test and the odds ratio (OR), with 95% confidence intervals (CI) used performed for estimates regarding genotype and allele frequencies. Results: There were statistically significant differences between groups regarding the mean bleeding on probing, mean attachment level and mean probing depth (p < 0.00001) indicating that the matching based on the evaluated groups was adequate. The x2 test found a statistically significant imbalance of genotypes between groups (p = 0.0172). The prevalence of CP was significantly higher in subjects harboring at least one A allele at position -1082 (AA and GA genotypes) in comparison to patients with the GG genotype (OR = 2.96; CI: 0.52; 5.41; p = 0.0099). Equally, subjects with the AA genotype were significantly associated to a diagnosis of CP (OR = 2.71; CI: 0.38; 5.04; p = 0.0231). On the other hand, subjects presenting a healthy periodontal status presented at least one G allele in comparison with the AA genotype (OR = 0.37; CI: 0.05, 0.69; p = 0.0231). For subjects with the GG genotype, the same positive association was observed (OR = 0.34; CI: 0.06, 0.62; p = 0.0099). There were no significant differences between groups amongst subjects with the GA genotype (OR = 1.19; CI: 0.22, 2.16; p = 0.6774). Conclusions: Within the limits of this study, IL-10 gene polymorphism at position -1082 does not appear to be associated to CP. Conversely, subjects with AA genotype seem to be at an increased risk of developing CP

Adiponectin, leptin and TNF-α serum levels in obese and normal weight Peruvian adults with and without chronic periodontitis

Background: TNF-α, an adipokine involved in systemic inflammation and a member of a group of cytokines that stimulate the acute phase reaction, has been related to the pathogenesis of both periodontitis and obesity. The objective of this study was to assess the serum levels of adiponectin, leptin and TNF-α of periodontally healthy normal weight (NW) patients, NW patients with chronic periodontitis (CP), periodontally healthy obese patients and obese patients with CP. Material and Methods: Ninety-three patients were enrolled in this cross-sectional study: 30 periodontally healthy NW patients; 18 NW patients with CP; 21 periodontally healthy obese patients; and 24 obese patients with CP. Analyses included clinical and anthropometric outcomes, as well as the assessment of serum levels of adiponectin, leptin and TNF-α by enzyme linked immunosorbent assay (ELISA) or fully automated chemiluminescence immunoassay. One-Way ANOVA, Kruskal-Wallis One-Way on Ranks, Dunn’s Test and multivariable logistic regression (MLR) analyses were conducted to estimate the degree of association between periodontitis and obesity. Results: Obese patients with CP showed significant more bleeding sites than the other three groups ( p <0.05). Moreover, patients from the NWCP and OPH showed similar BOP percentages, as well as OPH group showed more bleeding sites than the NWPH group ( p <0.05). The OPH group showed similar levels of adiponectin and leptin than the OCP group, but significantly higher than the NWPH and NWCP groups( p <0.05). MLR analyses showed that obesity was positively associated with the percentage of sites with bleeding on probing, with an odds ratio of 0.93 (95% confidence interval: -0.88, - 0.98; p =0.012). Conclusions: The serum levels of adiponectin, leptin and TNF-α were not influenced by CP. Obese patients showed almost 10% more sites with BoP. In chronic periodontitis patients, obese subjects presented significant more BOP sites than normal weight subject

Multi-year GNSS monitoring of atmospheric IWV over Central and South America for climate studies

Atmospheric water vapour has been acknowledged as an essential climate variable. Weather prediction and hazard assessment systems benefit from real-time observations, whereas long-term records contribute to climate studies. Nowadays, ground-based global navigation satellite system (GNSS) products have become widely employed, complementing satellite observations over the oceans. Although the past decade has seen a significant development of the GNSS infrastructure in Central and South America, its potential for atmospheric water vapour monitoring has not been fully exploited. With this in mind, we have performed a regional, 7-year-long and homogeneous analysis, comprising 136 GNSS tracking stations, obtaining high-rate and continuous observations of column-integrated water vapour and troposphere zenith total delay. As a preliminary application for this data set, we have estimated local water vapour trends, their significance, and their relation with specific climate regimes. We have found evidence of drying at temperate regions in South America, at a rate of about 2 % per decade, while a slow moistening of the troposphere over tropical regions is also weakly suggested by our results. Furthermore, we have assessed the regional performance of the empirical model GPT2w to blindly estimate troposphere delays. The model reproduces the observed mean delays fairly well, including their annual and semi-annual variations. Nevertheless, a long-term evaluation has shown systematical biases, up to 20 mm, probably inherited from the underlying atmospheric reanalysis. Additionally, the complete data set has been made openly available as supplementary material.Fil: Bianchi, Clara Eugenia. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Mendoza, Luciano Pedro Oscar. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Fernandez, Laura Isabel. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Natali, Maria Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Departamento de Georreferenciación Satelitaria; ArgentinaFil: Meza, Amalia Margarita. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Área Física Teórica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Moirano, Juan Francisco. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentin

Cardiopatías congénitas en pacientes del sistema público

En Argentina nacen cerca de 7.000 niños con cardiopatías congénitas (CC) al año, de los cuales, cerca del 2/3 requieren tratamiento quirúrgico antes del año de vida. 9 de cada 10 de los pacientes que acceden a la cirugía correctiva alcanzarán la edad adulta, con el riesgo consecuente de tener descendencia con el mismo u otro defecto cardiaco (estimado en 2-3% de recurrencia para hermanos y de 4% cuando se trate de madre a hijo). Actualmente, el Hospital de Pediatría Dr. Fernando Barreyro de la capital Misionera atiende hasta 50 consultas de cardiopatías por día. Esta estadística motivó el presente proyecto. Se buscó caracterizar las CC más frecuentes en la población infantil y juvenil atendida en el Hospital de Pediatría desde 2013 a la fecha, determinar si la frecuencia poblacional local concuerda con los valores de la media nacional publicada por la Sociedad Argentina de Pediatría y la Sociedad Argentina de Cardiología y finalmente se buscó identificar casos familiares afectados por el defecto congénito

Interpretación de las relaciones intrafamiliares y su incidencia en los comportamientos violentos de un grupo de alumnos de la escuela urbana San Luis del municipio de Sincelejo, Sucre

La investigación "Interpretación de las relaciones familiares y su incidencia en los comportamientos violentos de un grupo de alumnos de la Escuela Urbana San Luis surge de la necesidad de mejorar las relaciones en la familia y la escuela, dado al ambiente conflictivo en que se desenvuelven estas. El estudio contiene una breve descripción de la problemática que perturba el normal desarrollo de las actividades en la institución, destacando la importancia y necesidad de trabajar la violencia en el contexto familiar, para lo cual se formulan preguntas orientadoras, objetivos alcanzables, unas hipótesis teóricas comprobadas, apoyados en un marco teórico formado por dos grandes núcleos temáticos como son la familia esencialmente su estructura, vínculos afectivos, relaciones de violencia y marginalidad desde el punto de vista socio-económico; y el otro núcleo las relaciones de violencia en la escuela. Se emplea en esta investigación el enfoque etnográfico que permite describir el tipo de relaciones en el medio familiar, para lo cual se tuvo en xi cuenta los testimonios brindados por diez familias, cuyos hijos presentan comportamientos violentos Se hace un análisis descriptivo e interpretativo de los testimonios teniendo en cuenta las categorías de análisis Relaciones afectivas al interior de la familia, expresiones de violencia en la familia, autoridad ejercida en la familia y marginalidad en que vive la familia. Una vez obtenidos los resultados se elabora la propuesta de intervención pedagógica "Hacia el mejoramiento de las relaciones familiares" dirigida a docentes y padres de familia interesados en mejorar las relaciones violentas de los niños

In vitro larvicidal effect of a hydroalcoholic extract from Acacia cochliacantha leaf against ruminant parasitic nematodes

Larvicidal effect was evaluated using acacia cochliacantha leafThe aim of this study was to evaluate the in vitro lethal effect of a hydroalcoholic extract (HAE) from Acacia cochliacantha leaf against three gastrointestinal nematodes species (Haemonchus contortus, H. placei and Cooperiapunctata) of domestic ruminants. The HAE was assessed using five concentrations: 100, 125, 175, 150 and 200 mg/ml; 0.5% Ivermectin was used as a positive control and distilled water, as negative control. The data were normalized using the square root and analysed with a completely randomized design through ANOVA analysis using the general linealmodel (GLM) of the SAS program. The HAE tannin conten was determined through spectrophotometry (UV-visible) and the other major phenols, were identified by chromatographic processes. The results showed an in vitro larvicidal activity of the HAE against the three assessed nematode species with all assessed concentrations. A clear HAE increased concentration dependence effect was observed. The highest activity of the HAE was obtained at the highest concentration (close to 100%, P < 0.05). This result was similar to the one obtained with Ivermectin. On the other hand, the chemical analysis of HAE showed the presence of tannins, caffeoyls and coumaroyl derivates and quercetin as the main compounds. The results suggest that the HAE from this plant species pos- sess in vitro anthelmintic properties. The identified com- pounds in this study would good candidates for further in vivo researches.This study received financial support from CONACYT-Mexico (Project number 251244), INIFAP (Project number 9454133183, through the Researcher Retaining Program)