Integración de Repositorios Digitales para la Gestión del Conocimiento en el ámbito universitario Colombiano

This article presents the steps to realize the changes of integration and migration of information of digital repositories in different platforms of Open Source (Open Source) in order to guarantee the standardization of any proper informatic solutions of the Universities of High School (UHS). In addition to improving the access to the application preventing persons not authorized to the UHS from registering inside the system. Addition to this problem, it exists the one that hasappearing inside the Information Technologies and the Communications (ITCs), with the heyday of information that is registered second to second on a global scale by the phenomenon of the Web 2.0 [9]. Information that in most cases cannot be re-used so much by research centers and/or academic sector after there did not exist suitable informatic tools that allow to centralize the knowledge management in a certain place and of way specialized according to the different Basic Nuclei of the Knowledge (BNK) that exist inside the educational sector [5], without forgetting also the costs in the licenses of software that could exist. Although the movements of the free software [6] 7] and with the open source [8], which must not make a mistake, they have provided some informatic tools for the knowledge management; in most cases this tools cannot integrate between themselves with other information systems who has an UHS, due to few documentation that exists and/or to the only specification started to a certain computer language and/or engine of database and/or technological platform with which they were developed, between others. Forcing that in a certain UHS has to realize different implementations decentralized with redundant information in his information systems, without these being synchronized with other informatic solutions that the same institution has.Este artículo presenta los pasos para realizar los cambios de integración y migración de información de los repositorios digitales en diversas plataformas de código abierto (Open Source) con el fin de garantizar la estandarización de las soluciones informáticas propias de las Instituciones de Educación Superior (IES). Además de mejorar el acceso a la aplicación impendiendo que personas no autorizadas a la IES se registren dentro del sistema. Adición a este problema, existe el que se viene presentando dentro de las Tecnologías de la Información y las Comunicaciones (TICs), con el auge de información que es registrada segundo a segundo a nivel mundial por el fenómeno de la Web 2.0 [9]. Información que en la mayoría de los casos no puede ser reutilizada tanto por centros de investigación y/o sector académico al no existir adecuadas herramientas informáticas que permitan centralizar la gestión del conocimiento en un determinado sitio y de manera especializada según los diferentes Núcleos Básicos del Conocimiento (NBC) que existen dentro del sector educativo [5], sin olvidar además los costos en las licencias de software que puedan existir. Pese a que los movimientos del software libre [6][7] y del código abierto [8], los que no se deben confundir, hayan suministrado algunas herramientas informáticas para la gestión del conocimiento; en la mayoría de los casos estas herramientas no se pueden integrar entre sí con otros sistemas de información que tenga una IES, debido a la poca documentación que existe y/o a la especificación única dada a un determinado lenguaje de programación y/o motor de base de datos y/o plataforma tecnológica con que fueron desarrollados, entre otros. Obligando a que en una determinada IES tenga que realizar diferentes implementaciones descentralizadas con información redundante en sus sistemas de información, sin que éstas estén sincronizadas con otras soluciones informáticas que tenga la misma institución

The effects of retinol oral supplementation in 6-hydroxydopamine dopaminergic denervation model in Wistar rats

Vitamin A (retinol) is involved in signaling pathways regulating gene expression and was postulated to be a major antioxidant and anti-inflammatory compound of the diet. Parkinson's disease (PD) is a progressive neurodegenerative disorder, characterized by loss of nigral dopaminergic neurons, involving oxidative stress and pro-inflammatory activation. The aim of the present study was to evaluate the neuroprotective effects of retinol oral supplementation against 6-hydroxydopamine (6-OHDA, 12 μg per rat) nigrostriatal dopaminergic denervation in Wistar rats. Animals supplemented with retinol (retinyl palmitate, 3000 IU/kg/day) during 28 days exhibited increased retinol content in liver, although circulating retinol levels (serum) were unaltered. Retinol supplementation did not protect against the loss of dopaminergic neurons (assessed through tyrosine hydroxylase immunofluorescence and Western blot). Retinol supplementation prevented the effect of 6-OHDA on Iba-1 levels but had no effect on 6-OHDA-induced GFAP increase. Moreover, GFAP levels were increased by retinol supplementation alone. Rats pre-treated with retinol did not present oxidative damage or thiol redox modifications in liver, and the circulating levels of TNF-α, IL-1β, IL-6 and IL-10 were unaltered by retinol supplementation, demonstrating that the protocol used here did not cause systemic toxicity to animals. Our results indicate that oral retinol supplementation is not able to protect against 6-OHDA-induced dopaminergic denervation, and it may actually stimulate astrocyte reactivity without altering parameters of systemic toxicity

Integración de Repositorios Digitales para la Gestión del Conocimiento en el ámbito universitario Colombiano

This article presents the steps to realize the changes of integration and migration of information of digital repositories in different platforms of Open Source (Open Source) in order to guarantee the standardization of any proper informatic solutions of the Universities of High School (UHS). In addition to improving the access to the application preventing persons not authorized to the UHS from registering inside the system. Addition to this problem, it exists the one that hasappearing inside the Information Technologies and the Communications (ITCs), with the heyday of information that is registered second to second on a global scale by the phenomenon of the Web 2.0 [9]. Information that in most cases cannot be re-used so much by research centers and/or academic sector after there did not exist suitable informatic tools that allow to centralize the knowledge management in a certain place and of way specialized according to the different Basic Nuclei of the Knowledge (BNK) that exist inside the educational sector [5], without forgetting also the costs in the licenses of software that could exist. Although the movements of the free software [6] 7] and with the open source [8], which must not make a mistake, they have provided some informatic tools for the knowledge management; in most cases this tools cannot integrate between themselves with other information systems who has an UHS, due to few documentation that exists and/or to the only specification started to a certain computer language and/or engine of database and/or technological platform with which they were developed, between others. Forcing that in a certain UHS has to realize different implementations decentralized with redundant information in his information systems, without these being synchronized with other informatic solutions that the same institution has.Este artículo presenta los pasos para realizar los cambios de integración y migración de información de los repositorios digitales en diversas plataformas de código abierto (Open Source) con el fin de garantizar la estandarización de las soluciones informáticas propias de las Instituciones de Educación Superior (IES). Además de mejorar el acceso a la aplicación impendiendo que personas no autorizadas a la IES se registren dentro del sistema. Adición a este problema, existe el que se viene presentando dentro de las Tecnologías de la Información y las Comunicaciones (TICs), con el auge de información que es registrada segundo a segundo a nivel mundial por el fenómeno de la Web 2.0 [9]. Información que en la mayoría de los casos no puede ser reutilizada tanto por centros de investigación y/o sector académico al no existir adecuadas herramientas informáticas que permitan centralizar la gestión del conocimiento en un determinado sitio y de manera especializada según los diferentes Núcleos Básicos del Conocimiento (NBC) que existen dentro del sector educativo [5], sin olvidar además los costos en las licencias de software que puedan existir. Pese a que los movimientos del software libre [6][7] y del código abierto [8], los que no se deben confundir, hayan suministrado algunas herramientas informáticas para la gestión del conocimiento; en la mayoría de los casos estas herramientas no se pueden integrar entre sí con otros sistemas de información que tenga una IES, debido a la poca documentación que existe y/o a la especificación única dada a un determinado lenguaje de programación y/o motor de base de datos y/o plataforma tecnológica con que fueron desarrollados, entre otros. Obligando a que en una determinada IES tenga que realizar diferentes implementaciones descentralizadas con información redundante en sus sistemas de información, sin que éstas estén sincronizadas con otras soluciones informáticas que tenga la misma institución

Age and provenance of the Mio-Pleistocene sediments from the Sacaco area, Peruvian continental margin

International audienceOver the last decades, rocks from the East Pisco Basin (EPB), on the Central Peruvian coast (13 •-16 • S), have yielded an abundant and diverse collection of coastal-marine fossils, which are key for characterizing the onset and evolution of the modern Humboldt Current. Despite its paleontological richness, and after almost 40 years of study, the spatio-temporal context of the deposits of the southern part of the EPB (Sacaco area) remains only broadly constrained, being mostly tailored to particular vertebrate-rich levels occurring throughout the area. Here we build a composite stratigraphic section for the Sacaco area including three lithostratigraphic units (Pisco, Caracoles, and Pongo formations), which documents several discontinuities and intraformational unconformities. We infer depositional ages based on new radiometric (U-Pb), isotopic (Sr) and biostratigraphic data, synthesize previous litho-, chemo-, and bio-stratigraphic studies, and present a comprehensive chronostratigraphic review of the Mio-Pleistocene record for the Sacaco sub-basin that allows us to identify various local and basinal events. Our results indicate that, in the Sacaco area, the Pisco Formation ranges from ~9.6 to 4.5 Ma, the overlying Caracoles Formation from 2.7 to ~1.9 Ma, and the Pongo Formation accumulated from ~1.9 up to at least 1.4 Ma. These sedimentary successions accumulated in a continually subsiding setting and show a shallowing-upwards trend. Zircon U-Pb provenance analysis mainly record Neoproterozoic, Cretaceous, and Mio-Pleistocene populations, revealing discrete up-section changes in source areas. Mio-Pleistocene and Cretaceous sources are continuously present, while older recycled-orogen sources vary through time in presence and abundance, indicating either paleogeographic changes or source exhaustion

Age and provenance of the Mio-Pleistocene sediments from the Sacaco area, Peruvian continental margin

International audienceOver the last decades, rocks from the East Pisco Basin (EPB), on the Central Peruvian coast (13 •-16 • S), have yielded an abundant and diverse collection of coastal-marine fossils, which are key for characterizing the onset and evolution of the modern Humboldt Current. Despite its paleontological richness, and after almost 40 years of study, the spatio-temporal context of the deposits of the southern part of the EPB (Sacaco area) remains only broadly constrained, being mostly tailored to particular vertebrate-rich levels occurring throughout the area. Here we build a composite stratigraphic section for the Sacaco area including three lithostratigraphic units (Pisco, Caracoles, and Pongo formations), which documents several discontinuities and intraformational unconformities. We infer depositional ages based on new radiometric (U-Pb), isotopic (Sr) and biostratigraphic data, synthesize previous litho-, chemo-, and bio-stratigraphic studies, and present a comprehensive chronostratigraphic review of the Mio-Pleistocene record for the Sacaco sub-basin that allows us to identify various local and basinal events. Our results indicate that, in the Sacaco area, the Pisco Formation ranges from ~9.6 to 4.5 Ma, the overlying Caracoles Formation from 2.7 to ~1.9 Ma, and the Pongo Formation accumulated from ~1.9 up to at least 1.4 Ma. These sedimentary successions accumulated in a continually subsiding setting and show a shallowing-upwards trend. Zircon U-Pb provenance analysis mainly record Neoproterozoic, Cretaceous, and Mio-Pleistocene populations, revealing discrete up-section changes in source areas. Mio-Pleistocene and Cretaceous sources are continuously present, while older recycled-orogen sources vary through time in presence and abundance, indicating either paleogeographic changes or source exhaustion

Age and provenance of the Mio-Pleistocene sediments from the Sacaco area, Peruvian continental margin

International audienceOver the last decades, rocks from the East Pisco Basin (EPB), on the Central Peruvian coast (13 •-16 • S), have yielded an abundant and diverse collection of coastal-marine fossils, which are key for characterizing the onset and evolution of the modern Humboldt Current. Despite its paleontological richness, and after almost 40 years of study, the spatio-temporal context of the deposits of the southern part of the EPB (Sacaco area) remains only broadly constrained, being mostly tailored to particular vertebrate-rich levels occurring throughout the area. Here we build a composite stratigraphic section for the Sacaco area including three lithostratigraphic units (Pisco, Caracoles, and Pongo formations), which documents several discontinuities and intraformational unconformities. We infer depositional ages based on new radiometric (U-Pb), isotopic (Sr) and biostratigraphic data, synthesize previous litho-, chemo-, and bio-stratigraphic studies, and present a comprehensive chronostratigraphic review of the Mio-Pleistocene record for the Sacaco sub-basin that allows us to identify various local and basinal events. Our results indicate that, in the Sacaco area, the Pisco Formation ranges from ~9.6 to 4.5 Ma, the overlying Caracoles Formation from 2.7 to ~1.9 Ma, and the Pongo Formation accumulated from ~1.9 up to at least 1.4 Ma. These sedimentary successions accumulated in a continually subsiding setting and show a shallowing-upwards trend. Zircon U-Pb provenance analysis mainly record Neoproterozoic, Cretaceous, and Mio-Pleistocene populations, revealing discrete up-section changes in source areas. Mio-Pleistocene and Cretaceous sources are continuously present, while older recycled-orogen sources vary through time in presence and abundance, indicating either paleogeographic changes or source exhaustion

Age and provenance of the Mio-Pleistocene sediments from the Sacaco area, Peruvian continental margin

International audienceOver the last decades, rocks from the East Pisco Basin (EPB), on the Central Peruvian coast (13 •-16 • S), have yielded an abundant and diverse collection of coastal-marine fossils, which are key for characterizing the onset and evolution of the modern Humboldt Current. Despite its paleontological richness, and after almost 40 years of study, the spatio-temporal context of the deposits of the southern part of the EPB (Sacaco area) remains only broadly constrained, being mostly tailored to particular vertebrate-rich levels occurring throughout the area. Here we build a composite stratigraphic section for the Sacaco area including three lithostratigraphic units (Pisco, Caracoles, and Pongo formations), which documents several discontinuities and intraformational unconformities. We infer depositional ages based on new radiometric (U-Pb), isotopic (Sr) and biostratigraphic data, synthesize previous litho-, chemo-, and bio-stratigraphic studies, and present a comprehensive chronostratigraphic review of the Mio-Pleistocene record for the Sacaco sub-basin that allows us to identify various local and basinal events. Our results indicate that, in the Sacaco area, the Pisco Formation ranges from ~9.6 to 4.5 Ma, the overlying Caracoles Formation from 2.7 to ~1.9 Ma, and the Pongo Formation accumulated from ~1.9 up to at least 1.4 Ma. These sedimentary successions accumulated in a continually subsiding setting and show a shallowing-upwards trend. Zircon U-Pb provenance analysis mainly record Neoproterozoic, Cretaceous, and Mio-Pleistocene populations, revealing discrete up-section changes in source areas. Mio-Pleistocene and Cretaceous sources are continuously present, while older recycled-orogen sources vary through time in presence and abundance, indicating either paleogeographic changes or source exhaustion

Age and provenance of the Mio-Pleistocene sediments from the Sacaco area, Peruvian continental margin

International audienceOver the last decades, rocks from the East Pisco Basin (EPB), on the Central Peruvian coast (13 •-16 • S), have yielded an abundant and diverse collection of coastal-marine fossils, which are key for characterizing the onset and evolution of the modern Humboldt Current. Despite its paleontological richness, and after almost 40 years of study, the spatio-temporal context of the deposits of the southern part of the EPB (Sacaco area) remains only broadly constrained, being mostly tailored to particular vertebrate-rich levels occurring throughout the area. Here we build a composite stratigraphic section for the Sacaco area including three lithostratigraphic units (Pisco, Caracoles, and Pongo formations), which documents several discontinuities and intraformational unconformities. We infer depositional ages based on new radiometric (U-Pb), isotopic (Sr) and biostratigraphic data, synthesize previous litho-, chemo-, and bio-stratigraphic studies, and present a comprehensive chronostratigraphic review of the Mio-Pleistocene record for the Sacaco sub-basin that allows us to identify various local and basinal events. Our results indicate that, in the Sacaco area, the Pisco Formation ranges from ~9.6 to 4.5 Ma, the overlying Caracoles Formation from 2.7 to ~1.9 Ma, and the Pongo Formation accumulated from ~1.9 up to at least 1.4 Ma. These sedimentary successions accumulated in a continually subsiding setting and show a shallowing-upwards trend. Zircon U-Pb provenance analysis mainly record Neoproterozoic, Cretaceous, and Mio-Pleistocene populations, revealing discrete up-section changes in source areas. Mio-Pleistocene and Cretaceous sources are continuously present, while older recycled-orogen sources vary through time in presence and abundance, indicating either paleogeographic changes or source exhaustion

Age and provenance of the Mio-Pleistocene sediments from the Sacaco area, Peruvian continental margin

International audienceOver the last decades, rocks from the East Pisco Basin (EPB), on the Central Peruvian coast (13°-16°S), have yielded an abundant and diverse collection of coastal-marine fossils, which are key for characterizing the onset and evolution of the modern Humboldt Current. Despite its paleontological richness, and after almost 40 years of study, the spatio-temporal context of the deposits of the southern part of the EPB (Sacaco area) remains only broadly constrained, being mostly tailored to particular vertebrate-rich levels occurring throughout the area. Here we build a composite stratigraphic section for the Sacaco area including three lithostratigraphic units (Pisco, Caracoles, and Pongo formations), which documents several discontinuities and intraformational unconformities. We infer depositional ages based on new radiometric (U-Pb), isotopic (Sr) and biostratigraphic data, synthesize previous litho-, chemo-, and bio-stratigraphic studies, and present a comprehensive chronostratigraphic review of the Mio-Pleistocene record for the Sacaco sub-basin that allows us to identify various local and basinal events. Our results indicate that, in the Sacaco area, the Pisco Formation ranges from ∼9.6 to 4.5 Ma, the overlying Caracoles Formation from 2.7 to ∼1.9 Ma, and the Pongo Formation accumulated from ∼1.9 up to at least 1.4 Ma. These sedimentary successions accumulated in a continually subsiding setting and show a shallowing-upwards trend. Zircon U-Pb provenance analysis mainly record Neoproterozoic, Cretaceous, and Mio-Pleistocene populations, revealing discrete up-section changes in source areas. Mio-Pleistocene and Cretaceous sources are continuously present, while older recycled-orogen sources vary through time in presence and abundance, indicating either paleogeographic changes or source exhaustion

Memorias del primer Simposio Nacional de Ciencias Agronómicas

Primer simposio nacional de Ciencias Agronómicas: El renacer del espacio de discusión científica para el Agro colombiano