225 research outputs found
Investigation of Diving Moments of a Pursuit Airplane in the Ames 16-Foot High Speed Wind Tunnel
A pursuit type airplane encountered severe diving moments in high-speed dives which make recovery difficult. For the purpose of investigating these diving moments and finding means for their reduction, a 1/6-scale model of the airplane was tested in the 16-foot high-speed wind tunnel at Ames Aeronautical Laboratory. The test results indicate that up to a Mach number of at least 0.75, the limit of the tests, the dive-recovery difficulties can be alleviated and the longitudinal maneuverability improved by the substitution of a long symmetrical fuselage for the standard fuselage
Spin Relaxation Resonances Due to the Spin-Axis Interaction in Dense Rubidium and Cesium Vapor
Resonances in the magnetic decoupling curves for the spin relaxation of dense
alkali-metal vapors prove that much of the relaxation is due to the spin-axis
interaction in triplet dimers. Initial estimates of the spin-axis coupling
coefficients for the dimers are 290 MHz for Rb; 2500 MHz for Cs.Comment: submitted to Physical Review Letters, text + 3 figure
A Sino-German 6\ cm polarization survey of the Galactic plane. V. Large supernova remnants
Observations of large supernova remnants (SNRs) at high frequencies are rare,
but provide valuable information about their physical properties. The total
intensity and polarization properties of 16 large SNRs in the Galactic plane
were investigated based on observations of the Urumqi 6\ cm
polarization survey of the Galactic plane with an angular resolution of
9\farcm5. We extracted total intensity and linear polarization maps of large
SNRs from the Urumqi 6\ cm survey, obtained their integrated flux
densities, and derived the radio spectra in context with previously published
flux densities at various frequencies. In particular, Effelsberg 11\
cm and 21\ cm survey data were used for calculating integrated flux
densities. The 6\ cm polarization data also delineate the magnetic
field structures of the SNRs. We present the first total intensity maps at
6\ cm for SNRs G106.3+2.7, G114.3+0.3, G116.5+1.1, G166.0+4.3 (VRO
42.05.01), G205.5+0.5 (Monoceros Nebula) and G206.9+2.3 (PKS 0646+06) and the
first polarization measurements at 6\ cm for SNRs G82.2+5.3 (W63),
G106.3+2.7, G114.3+0.3, G116.5+1.1, G166.0+4.3 (VRO 42.05.01), G205.5+0.5
(Monoceros Nebula) and G206.9+2.3 (PKS 0646+06). Most of the newly derived
integrated radio spectra are consistent with previous results. The new flux
densities obtained from the Urumqi 6\ cm, Effelsberg 11\ cm
and 21\ cm surveys are crucial to determine the spectra of SNR
G65.1+0.6, G69.0+2.7 (CTB 80), G93.7-0.2 and G114.3+0.3. We find that
G192.81.1 (PKS 0607+17) consists of background sources, \ion{H}{II} regions
and the extended diffuse emission of thermal nature, and conclude that
G192.81.1 is not a SNR.Comment: 15 pages, 10 figures, accepted by A&\amp;A. Language improved. For
the version with high resolution figures, please go to:
http://zmtt.bao.ac.cn/6cm/paper/gxy_largeSNR.pd
Teaching energy conservation as a unifying principle in physics
In this work we present the design and assessment of a teaching sequence aimed at introducing the principle of energy conservation at post-compulsory secondary school level (16-18 year olds). The proposal is based on the result of research into teaching-learning difficulties and on the analysis of the physics framework. Evidence is shown that this teaching sequence, together with the methodology used in the classroom, may result in students having a better grasp of the principle of energy conservation. Keywords Physics education · Energy conceptions · Teaching activitie
Combining fish and benthic communities into multiple regimes reveals complex reef dynamics
Abstract Coral reefs worldwide face an uncertain future with many reefs reported to transition from being dominated by corals to macroalgae. However, given the complexity and diversity of the ecosystem, research on how regimes vary spatially and temporally is needed. Reef regimes are most often characterised by their benthic components; however, complex dynamics are associated with losses and gains in both fish and benthic assemblages. To capture this complexity, we synthesised 3,345 surveys from Hawai‘i to define reef regimes in terms of both fish and benthic assemblages. Model-based clustering revealed five distinct regimes that varied ecologically, and were spatially heterogeneous by island, depth and exposure. We identified a regime characteristic of a degraded state with low coral cover and fish biomass, one that had low coral but high fish biomass, as well as three other regimes that varied significantly in their ecology but were previously considered a single coral dominated regime. Analyses of time series data reflected complex system dynamics, with multiple transitions among regimes that were a function of both local and global stressors. Coupling fish and benthic communities into reef regimes to capture complex dynamics holds promise for monitoring reef change and guiding ecosystem-based management of coral reefs
Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2
Background: Interleukin-1-dependent increases in glycolysis promote allergic airways disease in mice and disruption of pyruvate kinase M2 (PKM2) activity is critical herein. Glutathione-S-transferase P (GSTP) has been implicated in asthma pathogenesis and regulates the oxidation state of proteins via S-glutathionylation. We addressed whether GSTP-dependent S-glutathionylation promotes allergic airways disease by promoting glycolytic reprogramming and whether it involves the disruption of PKM2. Methods: We used house dust mite (HDM) or interleukin-1β in C57BL6/NJ WT or mice that lack GSTP. Airway basal cells were stimulated with interleukin-1β and the selective GSTP inhibitor, TLK199. GSTP and PKM2 were evaluated in sputum samples of asthmatics and healthy controls and incorporated analysis of the U-BIOPRED severe asthma cohort database. Results: Ablation of Gstp decreased total S-glutathionylation and attenuated HDM-induced allergic airways disease and interleukin-1β-mediated inflammation. Gstp deletion or inhibition by TLK199 decreased the interleukin-1β-stimulated secretion of pro-inflammatory mediators and lactate by epithelial cells. 13C-glucose metabolomics showed decreased glycolysis flux at the pyruvate kinase step in response to TLK199. GSTP and PKM2 levels were increased in BAL of HDM-exposed mice as well as in sputum of asthmatics compared to controls. Sputum proteomics and transcriptomics revealed strong correlations between GSTP, PKM2, and the glycolysis pathway in asthma. Conclusions: GSTP contributes to the pathogenesis of allergic airways disease in association with enhanced glycolysis and oxidative disruption of PKM2. Our findings also suggest a PKM2-GSTP-glycolysis signature in asthma that is associated with severe disease
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