Antimicrobial Activity of Zingiber Officinale and Allium Sativum on some Drug Resistant Bacterial Isolates

Ginger and garlic are very important and useful spices and are used as therapeutic agent against many pathological infections. Increasing multi-drug resistance of pathogens forces researchers to find alternative compounds for treatment of infectious diseases. In this study, the antimicrobial potency of ginger and garlic were investigated against four clinical bacterial isolates. Three types of ginger and garlic extracts (aqueous extract, methanol extract and ethanol extract) were assayed separately against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Salmonella typhi. The antibacterial activity was determined by well diffusion method. The minimum inhibitory concentration (MIC) of different bacterial species varied from 1.5625mg/ml to 5.0mg/ml with ginger extracts having the lowest and garlic extracts having the highest respectively. All tested bacterial were most susceptible to the garlic aqueous extract and showed poor susceptibility to the ginger aqueous extract. However, ginger extracts from the mean zone of inhibition have higher antimicrobial activity when compared to garlic extracts with exception to garlic aqueous extract. This study encourages the use of spices especially ginger and garlic as alternative or supplementary medicine to reduce the burden of high cost, side effects and progressively increasing drug resistance of pathogens

Effects of Plastic Pollution of Soil on the Growth and Survival of Bacteria and Fungi

The study examined the effect of plastic waste on soil bacteria and fungi. The test soil samples were collected from Lokoja international market waste dump site and the control soil sample was collected from non plastic contaminated garden in Salem University, Lokoja. The samples were analysed using Gas chromatography with mass spectrometer. The test soil sample soil sample had high quantity of plastic contaminant which were Methylene chloride 17.45mg/kg, hexane 10.05mg/kg, chloroform 1.56mg/kg, toluene 5.87mg/kg, tetrachloroethylene 1.48mg/kg as compared to the control garden soil sample, which had methylene chloride 0.54mg/kg, hexane 0.26mg/kg, chloroform 0.31mg/kg, toluene 5.87mg/kg and tetrachloroethylene 0.01mg/kg. The result showed the presence of plastic in the soil and it effect on bacteria and fungi. The totals of 11 bacteria were isolated from both soil samples using nutrient agar. The bacteria isolated are; Corynebacterium spp. (12%), Enterobacter spp. (8%), Acinetobacter spp. (6%), Escherichia coli (16%), Epidermis, Bacillus subtilis (15%), Serratia sp. (8%), Proteus spp. (4%), Micrococcus luteus (7%), Flavobacterium spp. (10%), Pseudomonas aeruginosa (15%). Micrococcus luteus, Flavobacterium spp. and Pseudomonas aeruginose were not isolated in plastic composted soil sample due to the presence of plasticizers. The total of 6 fungi were isolated, namely Penicilliun expansion (12%), Sacchromyces sp. (24%), Aspergillus niger (19%), Fusarium spp. (20%), Rhizopus stolonifer (10%) and Mucor piriformis (15%). This study reveals the effect of plastic waste, as it inhibits the growth of microorganism that is important for soil activities, thereby reducing the soil nutrients, fertility and productivity

Outcome of Infertility Consultations in a tropical tertiary health institution in Nigeria

Aim: To examine the outcome of gynaecological consultations for infertility in a tropical Teaching Health facility.Material & Methods: This is a cross-sectional study of infertility cases seen at the Bowen University Teaching Hospital, Ogbomoso over a year (16 October, 2010 to 15 October, 2011). The patients were followed up for twelve months thereafter. Data collection was done using a designed profoma. All patients coming for gynaecological consultations because of infertility within the study period were included in the study after giving their informed consents. Patient information recorded in the profoma included age, parity, educational status, occupation, duration of infertility, investigations, modality of treatment and treatment outcome. Outcome was measured by the number of live births amongst treated patients.Results: A total of 195 patients presented for gynaecological consultations during the one year period; infertility was one of the commonest reasons for gynaecological consultation, accounting for 38.5% (75) of the cases. Tubal factor, 25(33.5%) was the commonest etiological cause. The treatment modality involved myomectomy (20, 26.6%), ovulation induction (20, 26.6%), laparoscopic adhesiolysis (8, 10.7%) and tubal surgery (5, 6.7%). Treatment of infertility resulted in 10 (13.3%) live births, with ovulation induction giving the highest percentage of live births (5, 50%).Conclusion: The outcome of treatment of infertility is poor. Therefore, establishing a standard assisted reproductive technology (ART) unit will be of immense value in improving the outcome.Keywords: Infertility, consultation, outcom

The Green Bank North Celestial Cap Pulsar Survey. III. 45 New Pulsar Timing Solutions

We provide timing solutions for 45 radio pulsars discovered by the Robert C. Byrd Green Bank Telescope. These pulsars were found in the Green Bank North Celestial Cap pulsar survey, an all-GBT-sky survey being carried out at a frequency of 350 MHz. We include pulsar timing data from the Green Bank Telescope and Low Frequency Array. Our sample includes five fully recycled millisecond pulsars (MSPs, three of which are in a binary system), a new relativistic double neutron star system, an intermediate-mass binary pulsar, a mode-changing pulsar, a 138 ms pulsar with a very low magnetic field, and several nulling pulsars. We have measured two post-Keplerian parameters and thus the masses of both objects in the double neutron star system. We also report a tentative companion mass measurement via Shapiro delay in a binary MSP. Two of the MSPs can be timed with high precision and have been included in pulsar timing arrays being used to search for low-frequency gravitational waves, while a third MSP is a member of the black widow class of binaries. Proper motion is measurable in five pulsars, and we provide an estimate of their space velocity. We report on an optical counterpart to a new black widow system and provide constraints on the optical counterparts to other binary MSPs. We also present a preliminary analysis of nulling pulsars in our sample. These results demonstrate the scientific return of long timing campaigns on pulsars of all types

Plasminogen Controls Inflammation and Pathogenesis of Influenza Virus Infections via Fibrinolysis

Detrimental inflammation of the lungs is a hallmark of severe influenza virus infections. Endothelial cells are the source of cytokine amplification, although mechanisms underlying this process are unknown. Here, using combined pharmacological and gene-deletion approaches, we show that plasminogen controls lung inflammation and pathogenesis of infections with influenza A/PR/8/34, highly pathogenic H5N1 and 2009 pandemic H1N1 viruses. Reduction of virus replication was not responsible

Long-term variations of the UV contrast on Venus observed by the Venus Monitoring Camera on board Venus Express

International audienceWe analyze the Venus ultraviolet (UV) reflectivity as observed by the Venus Monitoring Camera on board Venus Express over 2000 orbits in the years 2006 to 2011. We compare several laws for the photometric correction of global images of Venus, and find that the combined law of Lambert and Lommel-Seeliger is most suitable for our study. Our analysis of the corrected images reveals strong fluctuations in the reflectivity contrast between low and high latitude regions of up to 40%, that follow variations of the SO2 abundance above the cloud top. Additionally, the phase angle dependence of the contrast gradually change from weak to strong, which may be related with the vertical distribution of the unknown UV absorber and the overlaying upper haze layer. We suggest that these variations result from a combination of two processes. One is the meridional transport of SO2, which forms sulfuric acid aerosol particles at high latitudes. The other is the presence of vertical winds near the cloud top level, which control the vertical mixing of the unknown UV absorber and the upper haze

Verification of Seasonal Climate Forecast Towards Hydro-Climatic Information Needs of Rice Farmers in Northern Ghana

Farmers in sub-Saharan Africa face many difficulties when making farming decisions due to unexpected changes in weather and climate. Access to hydroclimatic information can potentially assist farmers to adapt. This study explores the extent to which seasonal climate forecasts can meet hydroclimatic information needs of rice farmers in northern Ghana. First, 62 rice farmers across 12 communities were interviewed about their information needs. Results showed that importance of hydroclimatic information depends on the frequency of use and farming type (rain-fed, irrigated, or both). Generally, farmers perceived rainfall distribution, dam water level, and temperature as very important information, followed by total rainfall amount and onset ranked as important. These findings informed our skills assessment of rainfall (Prcp), minimum temperature (Tmin), and maximum temperature (Tmax) from the European Centre for Medium-Range Weather Forecasts (ECMWF-S4) and at lead times of 0 to 2 months. Forecast bias, correlation, and skills for all variables vary with season and location but are generally unsystematic and relatively constant with forecast lead time. Making it possible to meet farmers’ needs at their most preferred lead time of 1 month before the farming season. ECMWF-S4 exhibited skill in Prcp, Tmin, and Tmax in northern Ghana except for a few grid cells in MAM for Prcp and SON for Tmin and Tmax. Tmin and Tmax forecasts were more skillful than Prcp. We conclude that the participatory coproduction approach used in this study provides better insight for understanding demand-driven climate information services and that the ECMWF-S4 seasonal forecast system has the potential to provide actionable hydroclimatic information that may support farmers’ decisions

Intraband spectroscopy of self-organized InAs/InAlAs nanostructures grown on InP(001)

InAs nanostructures on InAlAs/InP(0 0 1) have been fabricated using Stranski-Krastanov growth mode. Depending on growth conditions, a full coverage of the InAlAs surface by either InAs strings of elongated dots or isolated dots can be achieved. Giant intraband absorptions are observed at mid-infrared wavelengths in both nanostructures. The intraband resonances are strongly polarized in the layer plane as a consequence of the quantum confinement along either [1 1 0] and [1 −1 0] directions