Formule et titre inédits sur les dinars d’Abū ‘Inān Fāris (749/1348 - 759/1358)

Il s’agit de la présentation et la description de deux dinars mérinides inédits frappés à Fès au nom du sultan Abū ‘Inān Fāris. Cette description est suivie par un commentaire et une discussion du contenu de certaines légendes inscrites sur ces dinars

Generalized properties for Hanafi–Wold's procedure in partial least squares path modeling

AbstractPartial least squares path modeling is a statistical method that allows to analyze complex dependence relationships among several blocks of observed variables, each one represented by a latent variable. The computation of latent variable scores is an essential step of the method, achieved through an iterative procedure named here Hanafi–Wold's procedure. The present paper generalizes properties already known in the literature for this procedure, from which additional convergence results will be obtained

Le rapport d’audit de la qualité de l’école au Maroc: quelles normes?

L’objectif de cet article est de démontrer l’intérêt d’une approche managériale de l’école au Maroc. Ceci à travers une des fonctions clés du management au sens de Fayol (1924) : le contrôle ; une fonction davantage appréhendée et analysée par la théorie d’agence développée par Jensen et Meckling (1976) ainsi que par l’approche théorique du stakeholdering (Donaldson et Preston, 1995 ; Blair M., 1995 ; Jones, 1995) qui conçoit l’organisation comme « un nœud de contrats ». La conception d’un rapport d’audit de la qualité de l’école qui s’inspire des normes de rapport de l’audit financier permettrait de mieux définir les responsabilités des acteurs et intervenants au sein de l’école. Ceci est dicté par l’impact réel des rapports de certification des comptes sur les décisions des parties concernées, alors que ceux relatifs au système de l’éducation n’ont qu’un impact mitigé. C’est le cas des enquêtes internationales type TIMSS, PIRLS, PISA ou de la Banque Mondiale. Le constat est le même pour les enquêtes nationales telles que le rapport récent (novembre 2021) PNEA du Conseil Supérieur de l’Education, de la Formation et de la Recherche Scientifique (CSEFRS) sur les acquis des élèves de la 6ième du primaire et de la 3ième année du secondaire collégial

La théorie des stakeholders et la crise du Covid-19: analyse du comportement managérial d’une école privée

L’objectif de cet article est de contribuer à comprendre le comportement managérial d’une PME, en l’occurrence un cas d’une école privée à Tanger, à la lumière de la théorie des stakeholders (Freeman, 1984 ; Mitchell et al., 1997) élaborée dans la grande firme. Une approche qui trouve tout son intérêt dans un contexte de crise telle que la Covid-19 ; une crise processuelle qui remet en cause les références des stakeholders et leurs attentes en conséquence (Roux-Dufort, 2003). L’étude de cas permet d’analyser le changement du comportement des acteurs de l’école à l’aune des changements des attentes de ses différents stakeholders et l’efficacité de ce changement. Les sept types de stakeholders du modèle de Mitchell et al déclinés en 03 catégories ; « latents », « en attente » ou « définitifs » reflétant l’exhaustivité des cas de figure possibles des stakeholders ont pu être identifiés dans notre cas d’analyse. L’approche contingente de la PME (Torres, 2003), permet de mieux appréhender la question de l’adaptabilité/la transposition des approches théoriques et des outils de gestion de la grande firme à la PME tout en conservant leurs valeurs aussi bien scientifiques qu’opérationnels

(2,6-Difluoro­phen­yl)(4-methyl­piperidin-1-yl)methanone

In the title compound, C13H15F2NO, the piperidine ring adopts a chair conformation. The dihedral angle between the least-squares plane of the piperidine ring and the benzene ring is 48.75 (7)°. In the crystal structure, the mol­ecules are connected via C—H⋯O hydrogen bonds, forming a zigzag chain along the b axis

Actividad citotóxica del α-humuleno y del tras-cariofileno de Salvia officinalis en dos líneas celulares tumorales animal y humana

Background: The purpose of the present work is two-fold: the fractionation of Salvia officinalis essential oil and the cytotoxic study of this oil with its fractions “in vitro” tumor cell lines. Materials and Methods: S. officinalis essential oil was obtained by hydrodistillation and fractionated with column chromatography; the essential oil and its fractions were analyzed by gas chromatography (GC) coupled to mass spectrometry (MS). The cytotoxic activity was evaluated in cellular lines of breast cancer MCF-7, colon cancer HCT-116, and murine macrophage RAW264.7 cell lines by the MTT assay. Results: the sub-subfraction F1.1.1 of S. officinalis essential oil containing α-humulene present highest activity on RAW264.7 and HCT-116 with IC50 values of 41.9 and 77.3 μg/ml, respectively. The sub-subfraction F1.2.1 of S. officinalis essential oil with trans-caryophyllene showed less activity on RAW246.7 and HCT-116 with IC50 values of 90.5 and 145.8 μg/ml. Conclusion: This paper suggests that the α-humulene and trans-caryophyllene extracted from S.officinalis essential oil inhibit tumor cell growth.Antecedentes: Este trabajo tiene dos objetivos: el fraccionamiento del aceite esencial de la especie Salvia officinalis y la determinación de la citotoxicidad del mencionado aceite esencial con sus fracciones en líneas celulares tumorales “in vitro”. Material y Métodos: El aceite esencial de Salvia officinalis fue obtenido por hidrodestilación y fraccionado mediante cromatografía en columna; el aceite esencial y sus fracciones fueron analizadas mediante cromatografía de gases (GC) acoplada a espectrometría de masas (MS). La actividad citotóxica fue evaluada en líneas celulares de cáncer de mama MCF-7; cáncer de colon HCT-116 y en macrófago murino. RAW264.7 con el ensayo MTT. Resultados: La sub-subfracción F1.1.1 del aceite esencial de Salvia officinalis que contiene alfa-humuleno presenta la actividad mas acusada frente a las líneas celulares RAW264.7 y HCT-116, con valores de IC50 de 41,9 y de 77,3 μg/ml respectivamente. La sub-subfracción F1.2.1 del aceite esencial de Salvia officinalis con trans-cariofileno, muestra menor actividad sobre células RAW246.7 y HCT-116 con valores de IC50 de 90,5 y 145,8 μg/ml respectivamente. Conclusión: Estos resultados sugieren que el alfa-humuleno y el trans-cariofileno de los extractos del aceite esencial de Salvia officinalis inhiben el crecimiento de células tumorales

Deep Brain Stimulation in Moroccan Patients With Parkinson's Disease: The Experience of Neurology Department of Rabat

Introduction: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is known as a therapy of choice of advanced Parkinson's disease. The present study aimed to assess the beneficial and side effects of STN DBS in Moroccan Parkinsonian patients.Material and Methods: Thirty five patients underwent bilateral STN DBS from 2008 to 2016 in the Rabat University Hospital. Patients were assessed preoperatively and followed up for 6 to 12 months using the Unified Parkinson's Disease Rating Scale in four conditions (stimulation OFF and ON and medication OFF and ON), the levodopa-equivalent daily dose (LEDD), dyskinesia and fluctuation scores and PDQ39 scale for quality of life (QOL). Postoperative side effects were also recorded.Results: The mean age at disease onset was 42.31 ± 7.29 years [28–58] and the mean age at surgery was 54.66 ± 8.51 years [34–70]. The median disease duration was 11.95 ± 4.28 years [5–22]. Sixty-three percentage of patients were male. 11.4% of patients were tremor dominant while 45.71 showed akinetic-rigid form and 42.90 were classified as mixed phenotype. The LEDD before surgery was 1200 mg/day [800-1500]. All patients had motor fluctuations whereas non-motor fluctuations were present in 61.80% of cases. STN DBS decreased the LEDD by 51.72%, as the mean LEDD post-surgery was 450 [188-800]. The UPDRS-III was improved by 52.27%, dyskinesia score by 66.70% and motor fluctuations by 50%, whereas QOL improved by 27.12%. Post-operative side effects were hypophonia (2 cases), infection (3 cases), and pneumocephalus (2 cases).Conclusion: Our results showed that STN DBS is an effective treatment in Moroccan Parkinsonian patients leading to a major improvement of the most disabling symptoms (dyskinesia, motor fluctuation) and a better QOL

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake