Customer Portfolio Analysis Using the SOM

In order to compete for profitable customers, companies are looking to add value using Customer Relationship Management (CRM). One subset of CRM is customer segmentation, which is the process of dividing customers into groups based upon common features or needs. Segmentation methods can be used for customer portfolio analysis (CPA), the process of analyzing the profitability of customers. This study was made for a case organization, who wanted to identify their profitable and unprofitable customers, in order to gain knowledge on how to develop their marketing strategies. Data about the customers were gathered from the case organization’s own database. The Self-Organizing Map (SOM) was used to divide the customers into segments, which were then analyzed in light of product sales information

From Smart Meter Data to Pricing Intelligence -- Visual Data Mining towards Real-Time BI

The deployment of smart metering in the electricity industry has opened up the opportunity for real-time BI-enabled innovative business applications, such as demand response. Taking a holistic view of BI, this study introduced a visual data mining driven application in order to exemplify the potentials of real-time BI to the electricity businesses. The empirical findings indicate that such an application is capable of extracting actionable insights about customer’s electricity consumption patterns, which will lead to turn timely measured data into pricing intelligence. Based on the findings, we proposed a real-time BI framework, and discussed how it will facilitate the formulation of strategic initiatives for transforming the electricity utility towards sustainable growth. Our research is conducted by following the design science research paradigm. By addressing an emerging issue in the problem domain, it adds empirical knowledge to the BI research landscape

Customer Feedback Analysis using Collocations

Today’s ERP and CRM systems provide companies with nearly unlimited possibilities for collecting data concerning theircustomers. More and more of these data are more or less unstructured textual data. A good example of this type of data iscustomer feedback, which can potentially be used to improve customer satisfaction.However, merely getting an overview of what lies in an unstructured mass of text is an extremely challenging task. This isthe topic of the field of computational linguistics. Collocation analysis, one of the tools emerging from this field, is a tooldeveloped for this task in particular. In this paper, we use the collocation analysis to study a text corpora consisting of 64,806pieces of customer feedback collected through a case company’s online customer portal. Collocation analysis is shown to bea very useful tool for exploratory analysis of highly unstructured customer feedback

COMBINING VISUAL CUSTOMER SEGMENTATION AND RESPONSE MODELING

Customer Relationship Management (CRM) is a central part of Business Intelligence and sales campaigns are often used for improving customer relationships. This paper explores customer behavior during sales campaigns. We provide a visual, data-driven and efficient framework for customer segmentation and campaign-response modeling. First, the customers are grouped by purchasing behavior characteristics using a self-organizing map. To this behavioral segmentation model, we link segment migration patterns using feature plane representations. This enables visual monitoring of the customer base and tracking customer behavior before and during sales campaigns. In addition to the general segment migration patterns, this method provides the capability to drill down into each segment to visually explore the dynamics. The framework is applied to a department store chain with more than one million customers

Assessing the Feasibility of Self Organizing Maps for Data Mining Financial Information

Analyzing financial performance in today’s information-rich society can be a daunting task. With the evolution of the Internet, access to massive amounts of financial data, typically in the form of financial statements, is widespread. Managers and stakeholders are in need of a data-mining tool allowing them to quickly and accurately analyze this data. An emerging technique that may be suited for this application is the self-organizing map. The purpose of this study was to evaluate the performance of self-organizing maps for analyzing financial performance of international pulp and paper companies. For the study, financial data, in the form of seven financial ratios, was collected, using the Internet as the primary source of information. A total of 77 companies, and six regional averages, were included in the study. The time frame of the study was the period 1995-00. An example analysis was performed, and the results analyzed based on information contained in the annual reports. The results of the study indicate that self-organizing maps can be feasible tools for the financial analysis of large amounts of financial data

Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans

Clonal hematopoiesis driven by somatic heterozygous TET2 loss is linked to malignant degeneration via consequent aberrant DNA methylation, and possibly to cardiovascular disease via increased cytokine and chemokine expression as reported in mice. Here, we discover a germline TET2 mutation in a lymphoma family. We observe neither unusual predisposition to atherosclerosis nor abnormal pro-inflammatory cytokine or chemokine expression. The latter finding is confirmed in cells from three additional unrelated TET2 germline mutation carriers. The TET2 defect elevates blood DNA methylation levels, especially at active enhancers and cell-type specific regulatory regions with binding sequences of master transcription factors involved in hematopoiesis. The regions display reduced methylation relative to all open chromatin regions in four DNMT3A germline mutation carriers, potentially due to TET2-mediated oxidation. Our findings provide insight into the interplay between epigenetic modulators and transcription factor activity in hematological neoplasia, but do not confirm the putative role of TET2 in atherosclerosis.Peer reviewe

Human Papillomavirus Genotype Distribution in Czech Women and Men with Diseases Etiologically Linked to HPV

The HPV prevalence and genotype distribution are important for the estimation of the impact of HPV-based cervical cancer screening and HPV vaccination on the incidence of diseases etiologically linked to HPVs. The HPV genotype distribution varies across different geographical regions. Therefore, we investigated the type-specific HPV prevalence in Czech women and men with anogenital diseases.We analyzed 157 squamous cell carcinoma samples, 695 precancerous lesion samples and 64 cervical, vulvar and anal condylomata acuminate samples. HPV detection and typing were performed by PCR with GP5+/6+ primers, reverse line blot assay and sequencing. samples. HPV types 6 and/or 11 were detected in 84% samples of condylomata acuminate samples.The prevalence of vaccinal and related HPV types in patients with HPV-associated diseases in the Czech Republic is very high. We may assume that the implementation of routine vaccination against HPV would greatly reduce the burden of HPV-associated diseases in the Czech Republic

Development and validation of combined symptom-medication scores for allergic rhinitis*

Background Validated combined symptom-medication scores (CSMSs) are needed to investigate the effects of allergic rhinitis treatments. This study aimed to use real-life data from the MASK-air(R) app to generate and validate hypothesis- and data-driven CSMSs. Methods We used MASK-air(R) data to assess the concurrent validity, test-retest reliability and responsiveness of one hypothesis-driven CSMS (modified CSMS: mCSMS), one mixed hypothesis- and data-driven score (mixed score), and several data-driven CSMSs. The latter were generated with MASK-air(R) data following cluster analysis and regression models or factor analysis. These CSMSs were compared with scales measuring (i) the impact of rhinitis on work productivity (visual analogue scale [VAS] of work of MASK-air(R), and Work Productivity and Activity Impairment: Allergy Specific [WPAI-AS]), (ii) quality-of-life (EQ-5D VAS) and (iii) control of allergic diseases (Control of Allergic Rhinitis and Asthma Test [CARAT]). Results We assessed 317,176 days of MASK-air(R) use from 17,780 users aged 16-90 years, in 25 countries. The mCSMS and the factor analyses-based CSMSs displayed poorer validity and responsiveness compared to the remaining CSMSs. The latter displayed moderate-to-strong correlations with the tested comparators, high test-retest reliability and moderate-to-large responsiveness. Among data-driven CSMSs, a better performance was observed for cluster analyses-based CSMSs. High accuracy (capacity of discriminating different levels of rhinitis control) was observed for the latter (AUC-ROC = 0.904) and for the mixed CSMS (AUC-ROC = 0.820). Conclusion The mixed CSMS and the cluster-based CSMSs presented medium-high validity, reliability and accuracy, rendering them as candidates for primary endpoints in future rhinitis trials.Peer reviewe

Consistent trajectories of rhinitis control and treatment in 16,177 weeks : The MASK-air (R) longitudinal study

Introduction: Data from mHealth apps can provide valuable information on rhinitis control and treatment patterns. However, in MASK-air (R), these data have only been analyzed cross-sectionally, without considering the changes of symptoms over time. We analyzed data from MASK-air (R) longitudinally, clustering weeks according to reported rhinitis symptoms.Methods: We analyzed MASK-air (R) data, assessing the weeks for which patients had answered a rhinitis daily questionnaire on all 7days. We firstly used k-means clustering algorithms for longitudinal data to define clusters of weeks according to the trajectories of reported daily rhinitis symptoms. Clustering was applied separately for weeks when medication was reported or not. We compared obtained clusters on symptoms and rhinitis medication patterns. We then used the latent class mixture model to assess the robustness of results.Results: We analyzed 113,239 days (16,177 complete weeks) from 2590 patients (mean age +/- SD = 39.1 +/- 13.7 years). The first clustering algorithm identified ten clusters among weeks with medication use: seven with low variability in rhinitis control during the week and three with highly-variable control. Clusters with poorly-controlled rhinitis displayed a higher frequency of rhinitis co-medication, a more frequent change of medication schemes and more pronounced seasonal patterns. Six clusters were identified in weeks when no rhinitis medication was used, displaying similar control patterns. The second clustering method provided similar results. Moreover, patients displayed consistent levels of rhinitis control, reporting several weeks with similar levels of control.Conclusions: We identified 16 patterns of weekly rhinitis control. Co-medication and medication change schemes were common in uncontrolled weeks, reinforcing the hypothesis that patients treat themselves according to their symptoms.[GRAPHICS].Peer reviewe