1,273 research outputs found
Civic Engagement, Community Attachment, and the Limitations of Social Media
Paper presented at the 80th Meeting of the American Society for Public Administration.In the past decade, social media has emerged as a popular tool for promoting volunteerism, giving, and community engagement. Public and nonprofit managers often feel pressure to use social media platforms to engage with the public and frequently seek advice on how to increase reach. However, as with many things, quantity does not always equal quality. Using data from interviews with 40 community leaders in the Upper Midwest, this research seeks to expand the existing literature on the role of social media and community engagement behaviors by providing a critical analysis of its usefulness and limitations.This material is based upon work supported by theNational Science Foundation under Grant No. 1822228.https://deepblue.lib.umich.edu/bitstream/2027.42/148325/1/ASPA_Million_Edwards_Hemphill_Final.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/148325/2/ASPA_Presentation_Small.pdfDescription of ASPA_Million_Edwards_Hemphill_Final.pdf : Extended AbstractDescription of ASPA_Presentation_Small.pdf : Presentation Slide
Anticipated regret to increase uptake of colorectal cancer screening (ARTICS):a randomised controlled trial
Objective. Screening is key to early detection of colorectal cancer. Our aim was to determine whether a simple anticipated regret (AR) intervention could increase colorectal cancer screening uptake. Methods. We conducted a randomised controlled trial of a simple, questionnaire-based AR intervention, delivered alongside existing pre-notification letters. 60,000 adults aged 50-74 from the Scottish National Screening programme were randomised to: 1) no questionnaire (control), 2) Health Locus of Control questionnaire (HLOC) or 3) HLOC plus anticipated regret questionnaire (AR). Primary outcome was guaiac Faecal Occult Blood Test (FOBT) return. Secondary outcomes included intention to return test kit and perceived disgust (ICK). Results. 59,366 people were analysed as allocated (Intentionto- treat (ITT)); there were no overall differences between treatment groups on FOBT uptake (control: 57.3%, HLOC: 56.9%, AR: 57.4%). 13,645 (34.2%) people returned questionnaires. Analysis of the secondary questionnaire measures showed that AR had an indirect effect on FOBT uptake via intention, whilst ICK had a direct effect on FOBT uptake over and above intention. The effect of AR on FOBT uptake was also moderated by intention strength: for less than strong intenders only, uptake was 4.2% higher in the AR (84.6%) versus the HLOC group (80.4%) (95% CI for difference (2.0, 6.5)). Conclusion. The findings show that psychological concepts including anticipated regret and perceived disgust (ICK) are important factors in determining FOBT uptake. However, there was no simple effect of the AR intervention in the ITT. We conclude that exposure to AR in those with low intentions may be required to increase FOBT uptake. Current controlled trials: www.controlledtrials. com number: ISRCTN74986452
Imiquimod 3.75% Cream Applied Daily to Treat Anogenital Warts: Combined Results from Women in Two Randomized, Placebo-Controlled Studies
Objective. To evaluate if new imiquimod formulations using a shorter treatment duration are safe and efficacious to treat anogenital warts. Methods. In two studies 534 women ≥12 years of age (mean 33.4) with 2–30 warts (mean 7.9) and total wart area ≥10 mm2 (mean 166.3) were randomized (1 : 2 : 2) to placebo (106), imiquimod 2.5% (212) or 3.75% (216) creams applied once daily until complete clearance or a maximum of 8 weeks. Results. For placebo, imiquimod 2.5% and 3.75%, respectively, complete clearance of all warts was achieved in 14.2%, 28.3%, and 36.6% of women (intent-to-treat, P = 0.008 imiquimod 2.5%, and P < 0.001 3.75% versus placebo). Mean changes in wart counts were −10.7%, −50.9%, and −63.5% (per-protocol, P < 0.001 each active versus placebo) and safety-related discontinuation rates 0.9%, 1.4%, and 2.3%. Conclusions. Imiquimod 3.75% applied daily for up to 8 weeks was well tolerated and superior to placebo in treating women with external anogenital warts
Anticipated regret to increase uptake of colorectal cancer screening in Scotland (ARTICS): Study protocol for a randomised controlled trial
Background: Colorectal cancer is the second leading cause of cancer deaths in the UK. Screening is key to early detection. The Scottish programme of colorectal cancer screening is running successfully, and involves all adults aged between 50 and 74 years being invited to post back a faecal sample for testing every 2 years. However, screening uptake is sub-optimal: for example rates for the period November 2009 to October 2011 ranged from just 39% for males living in the most deprived areas to 67% for least deprived females. Recent research has shown that asking people to consider the emotional consequences of not participating in screening (anticipated regret) can lead to a significant increase in screening uptake. Methods/Design: We will test a simple anticipated regret manipulation, in a large randomised controlled trial with 60,000 members of the general public. They will be randomly allocated to one of 3 arms, no questionnaire, control questionnaire or anticipated regret questionnaire. The primary outcome will be screening test kit return. Results will also be examined by demographic variables (age, gender, deprivation) as these are currently related to screening kit return. Discussion: If this anticipated regret intervention leads to a significant increase in colorectal cancer screening kit returns, this would represent a rare example of a theoretically-driven, simple intervention that could result in earlier detection of colorectal cancer and many more lives saved. Trial registration: Current Controlled trials: ISRCTN7498645
Quantitative Assessment of the Impact of Standard Agreement Templates on Multisite Clinical Trial Start Up Time
The worldwide marine radiocarbon reservoir effect: definitions, mechanisms, and prospects
When a carbon reservoir has a lower radiocarbon content than the atmosphere, this is referred to as a reservoir effect. This is expressed as an offset between the radiocarbon ages of samples from the two reservoirs at a single point in time. The marine reservoir effect (MRE) has been a major concern in the radiocarbon community, as it introduces an additional source of error that is often difficult to accurately quantify. For this reason, researchers are often reluctant to date marine material where they have another option. The influence of this phenomenon makes the study of the MRE important for a broad range of applications. The advent of Accelerator Mass Spectrometry (AMS) has reduced sample size requirements and increased measurement precision, in turn increasing the number of studies seeking to measure marine samples. These studies rely on overcoming the influence of the MRE on marine radiocarbon dates through the worldwide quantification of the local parameter ΔR, that is, the local variation from the global average MRE. Furthermore, the strong dependence on ocean dynamics makes the MRE a useful indicator for changes in oceanic circulation, carbon exchange between reservoirs, and the fate of atmospheric CO2, all of which impact Earth's climate. This article explores data from the Marine Reservoir Database and reviews the place of natural radiocarbon in oceanic records, focusing on key questions (e.g., changes in ocean dynamics) that have been answered by MRE studies and on their application to different subjects
Studies of the decays D^0 \rightarrow K_S^0K^-\pi^+ and D^0 \rightarrow K_S^0K^+\pi^-
The first measurements of the coherence factor R_{K_S^0K\pi} and the average
strong--phase difference \delta^{K_S^0K\pi} in D^0 \to K_S^0 K^\mp\pi^\pm
decays are reported. These parameters can be used to improve the determination
of the unitary triangle angle \gamma\ in B^- \rightarrow
decays, where is either a D^0 or a D^0-bar meson decaying to
the same final state, and also in studies of charm mixing. The measurements of
the coherence factor and strong-phase difference are made using
quantum-correlated, fully-reconstructed D^0D^0-bar pairs produced in e^+e^-
collisions at the \psi(3770) resonance. The measured values are R_{K_S^0K\pi} =
0.70 \pm 0.08 and \delta^{K_S^0K\pi} = (0.1 \pm 15.7) for an
unrestricted kinematic region and R_{K*K} = 0.94 \pm 0.12 and \delta^{K*K} =
(-16.6 \pm 18.4) for a region where the combined K_S^0 \pi^\pm
invariant mass is within 100 MeV/c^2 of the K^{*}(892)^\pm mass. These results
indicate a significant level of coherence in the decay. In addition, isobar
models are presented for the two decays, which show the dominance of the
K^*(892)^\pm resonance. The branching ratio {B}(D^0 \rightarrow
K_S^0K^+\pi^-)/{B}(D^0 \rightarrow K_S^0K^-\pi^+) is determined to be 0.592 \pm
0.044 (stat.) \pm 0.018 (syst.), which is more precise than previous
measurements.Comment: 38 pages. Version 3 updated to include the erratum information.
Errors corrected in Eqs (25), (26), 28). Fit results updated accordingly, and
external inputs updated to latest best known values. Typo corrected in Eq(3)-
no other consequence
Updated Measurement of the Strong Phase in D0 --> K+pi- Decay Using Quantum Correlations in e+e- --> D0 D0bar at CLEO
We analyze a sample of 3 million quantum-correlated D0 D0bar pairs from 818
pb^-1 of e+e- collision data collected with the CLEO-c detector at E_cm = 3.77
GeV, to give an updated measurement of \cos\delta and a first determination of
\sin\delta, where \delta is the relative strong phase between doubly
Cabibbo-suppressed D0 --> K+pi- and Cabibbo-favored D0bar --> K+pi- decay
amplitudes. With no inputs from other experiments, we find \cos\delta = 0.81
+0.22+0.07 -0.18-0.05, \sin\delta = -0.01 +- 0.41 +- 0.04, and |\delta| = 10
+28+13 -53-0 degrees. By including external measurements of mixing parameters,
we find alternative values of \cos\delta = 1.15 +0.19+0.00 -0.17-0.08,
\sin\delta = 0.56 +0.32+0.21 -0.31-0.20, and \delta = (18 +11-17) degrees. Our
results can be used to improve the world average uncertainty on the mixing
parameter y by approximately 10%.Comment: Minor revisions, version accepted by PR
Higher-order multipole amplitudes in charmonium radiative transitions
Using 24 million decays in CLEO-c, we have searched
for higher multipole admixtures in electric-dipole-dominated radiative
transitions in charmonia. We find good agreement between our data and
theoretical predictions for magnetic quadrupole (M2) amplitudes in the
transitions and ,
in striking contrast to some previous measurements. Let and
denote the normalized M2 amplitudes in the respective aforementioned decays,
where the superscript refers to the angular momentum of the . By
performing unbinned maximum likelihood fits to full five-parameter angular
distributions, we determine the ratios and , where
the theoretical predictions are independent of the charmed quark magnetic
moment and are and .Comment: 32 pages, 7 figures, acceptance updat
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