10 research outputs found
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity.
- Author
- Aanensen David M
- Abudahab Khalil
- Acheson Erwan
- Adams Alexander
- Adams Helen
- Adriaenssens Evelien M
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad SY
- Alam Mohammad T
- Alcolea-Medina Adela
- Alderton Alex
- Alikhan Nabil-Fareed
- Allan John
- Allara Elias
- Amato Roberto
- Andersson Monique
- Angyal Adrienn
- Aranday-Cortes Elihu
- Ariani Cristina
- Asad Hibo
- Asamaphan Patawee
- Ashworth Jordan
- Atkinson Laura
- Attwood Stephen
- Auckland Cressida
- Awan Ali R
- Aydin Alp
- Baker David J
- Baker Paul
- Balcazar Carlos E
- Ball Jonathan
- Barton Edward
- Bashton Matthew
- Batra Rahul
- Baxter Laura
- Beale Mathew A
- Beaver Charlotte
- Beckett Angela
- Beer Robert
- Beggs Andrew
- Bell Andrew
- Bellis Katherine L
- Berger Duncan J
- Berriman Matt
- Berry Lisa
- Berry Louise
- Betancor Gilberto
- Betteridge Emma
- Bewshea Claire M
- Bibby David
- Bicknell Kelly
- Birchley Alec
- Bird Paul
- Bishop Chloe
- Blane Beth
- Bolt Frances
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Boyd Olivia
- Boyes John
- Bradley Declan T
- Bradshaw Daniel
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgewater Hannah E
- Brooks Tony T
- Broos Alice
- Brown Julianne Rose
- Brown Paul E
- Brown Rebecca
- Brunker Kirstyn
- Bucca Giselda
- Buck David
- Buddenborg Sarah K
- Bull Matthew
- Bull Matthew
- Burton-Fanning Shirelle
- Butcher Ethan
- Caddy Sarah L
- Caller Laura G
- Campbell Sharon
- Carlile Matthew
- Carmichael Stephen N
- Casey Anna
- Castellano Sergi
- Chalker Vicki
- Chand Meera
- Chapman Michael R
- Chappell Joseph G
- Charalampous Themoula
- Charles Ian G
- Chaudhry Yasmin
- Chauhan Anoop J
- Cheng Jeffrey KJ
- Churcher Carol M
- Clark Gemma
- Coll Francesc
- Collins Jennifer
- Colquhoun Rachel
- Colquhoun Rachel M
- Connor Thomas R
- Connor Thomas R
- Constantinidou Chrystala
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nicholas
- Cortes Nick
- Cottrell Simon
- Coupland Lindsay J
- Cowell Angela
- Cox Alison
- Craine Noel
- Cronin Michelle
- Crooke Derrick
- Curran Martin D
- Curran Tanya
- da Silva Filipe Ana
- da Silva Filipe Ana
- Dabrera Gavin
- Danesh John
- Darby Alistair C
- Davidson Rose K
- Davies Alisha
- Davis Thomas
- de Cesare Mariateresa
- De Lacy Elen
- de Oliveira Martins Leonardo
- de Silva Thushan I
- Debebe Johnny
- Dervisevic Samir
- Dewar Rebecca
- Dias Joana
- Diaz Maria
- Dibling Thomas
- Dorman Matthew J
- Downing Fatima
- Drury Eleanor
- du Plessis Louis
- Duckworth Nichola
- Dyal Patricia L
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- Eldirdiri Sahar
- Ellaby Nicholas
- Ellard Sian
- Elliott Scott
- Eltringham Gary
- Elumogo Ngozi
- Essex Sarah
- Evans Cariad
- Evans Johnathan M
- Eyre David
- Fairley Derek J
- Fallon Karlie
- Farbos Audrey
- Farr Ben
- Feltwell Theresa
- Fina Laia
- Findlay Jacqueline
- Fisher Chloe L
- Fleming Vicki M
- Forrest Leysa M
- Forrest Sally
- Foulser Luke
- Francois Sarah
- Fraser Christophe
- Freeman Timothy M
- Frost Lucy R
- Fuller William
- Gallagher Eileen
- Gallagher Michael D
- Garcia-Casado Maria V
- Gaskin Amy
- Gatica-Wilcox Bree
- Gavriil Artemis
- Geidelberg Lily
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P
- Gifford Laura
- Gilbert Lauren
- Gill Harmeet K
- Gilroy Rachel AJ
- Girgis Sophia T
- Glaysher Sharon
- Golubchik Tanya
- Goncalves Sonia
- Goodfellow Ian
- Goodfellow Ian G
- Goodwin Scott
- Graham Clive
- Graham Lee
- Grammatopoulos Dimitris
- Green Angie
- Green Luke R
- Greenaway Jane
- Gregory Richard
- Griffith Luke
- Groves Danielle C
- Groves Natalie
- Guest Martyn
- Gulliver Huw
- Gutierrez Ana Victoria
- Hadjirin Nazreen F
- Haldenby Sam T
- Hale Antony D
- Hall Grant
- Halstead Fenella
- Hamilton William L
- Haque Tanzina
- Harper Katherine L
- Harris Kathryn Ann
- Harrison Ewan M
- Harrison Ian
- Harrison James W
- Hartman Hassan
- Hattersley Andrew
- Heaney Judith
- Helmer Thomas
- Hesketh Andrew R
- Heyburn David
- Higginson Ellen E
- Hill Verity
- Hill Verity
- Hilvers Ember
- Hiscox Julian A
- Holden Matthew TG
- Holmes Alison
- Holmes Christopher
- Holmes Nadine
- Hoosdally Sarah
- Hopes Richard
- Hosmillo Myra
- Houldcroft Charlotte J
- Howe Robin
- Howson-Wells Hannah C
- Hubb Jonathan
- Hughes Joseph
- Hughes Margaret
- Hunter Adam D
- Hutchings Stephanie
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Jackson Ben
- Jackson Ben
- Jackson David A
- Jackson David K
- Jackson Kathryn A
- Jahun Aminu S
- James Keith
- Jamrozy Dorota
- Jarrett Ruth
- Jeffries Aaron R
- Jesudason Natasha
- Jesudason Natasha G
- John Michaela
- Johnson Kate
- Johnson Natasha
- Johnson Rob
- Johnson Robert
- Johnston Ian
- Jones Hannah
- Jones Katie
- Jones Rachel
- Jones Sophie
- Jorgensen David
- Jorgensen David
- Joseph Amelia
- Justice Anita
- Kane Leanne
- Kay Gemma L
- Kay Sally
- Keatley Jon-Paul
- Keeley Alexander J
- Kenyon Anita
- Kermack Leanne M
- Khakh Manjinder
- Khokhar Fahad A
- Kidd Stephen
- Kingsley Robert A
- Kitchen Christine
- Knight Bridget A
- Kolyva Anastasia
- Koshy Cherian
- Kraemer Moritz
- Kristiansen Mark
- Kumziene-Summerhayes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Langford Cordelia
- Lawniczak Mara
- Le-Viet Thanh
- Lee David
- Lee Jack CD
- Letchford Laura
- Levene Nick
- Levett Lisa J
- Li Kathy
- Li Kathy K
- Liggett Steven
- Lindsey Benjamin B
- Lister Michelle M
- Livett Rich
- Lloyd Allyson
- Lo Stephanie
- Loh Joshua
- Loman Nicholas J
- Loman Nicholas J
- Loose Matthew W
- Loveson Katie F
- Lowe Hannah
- Lucaci Anita O
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A
- Macfarlane-Smith Louissa R
- Machin Nicholas W
- MacIntyre-Cockett George
- Madona Pinglawathee
- Maes Mailis
- Mahungu Tabitha W
- Mair Daniel
- Maksimovic Joshua
- Manesis Nikos
- Manley Robin
- Manso Carmen
- Marchbank Angela
- Martincorena Inigo
- Martinez-Nunez Rocio T
- Masoli Jane AH
- Mason Jenifer
- Mather Alison E
- Mbisa Tamyo
- McCluggage Kathryn
- McClure Patrick C
- McCrone John T
- McCrone JT
- McGuigan Samantha
- McHugh Martin P
- McKenna James P
- McKerr Caoimhe
- McMinn Liz
- McMurray Claire
- Meader Emma J
- Meadows Lizzie
- Menegazzo Mirko
- Meredith Luke W
- Merrick Ian
- Mestek-Boukhibar Lamia
- Miah Shahjahan
- Michell Stephen L
- Michelsen Michelle L
- Molnar Zoltan
- Monaghan Lynn
- Mookerjee Siddharth
- Moore Catherine
- Moore Catrin
- Moore Christopher
- Moore Nathan
- Morgan Mari
- Morgan Sian
- Mori Matilde
- Moses Samuel
- Muir Peter
- Munn Robert
- Myers Richard
- Nascimento Fabricia F
- Nascimento Fabricia F
- Naydenova Plamena
- Neaverson Alexandra S
- Nebbia Gaia
- Nelson Andrew
- Nelson Charlotte
- Nelson Rachel
- Nicholls Sam
- Nicholls Samuel M
- Nichols Jenna
- Niebel Marc O
- Niola Paola
- Nomikou Kyriaki
- O'Toole Elaine
- O'Toole Áine
- Orton Richard J
- Osman Husam
- Ott Sascha
- O’Grady Justin
- O’Toole Áine
- Pacchiarini Nicole
- Pacchiarini Nicole
- Padgett Debra
- Page Andrew J
- Palmer Sophie
- Palmer Steve
- Panchbhaya Yasmin N
- Pandey Sarojini
- Park Naomi
- Parker Matthew D
- Parmar Surendra
- Parr Yasmin A
- Parsons Paul J
- Partridge David G
- Pascall David J
- Patel Gaurang
- Patel Minal
- Patel Vineet
- Paterson Steve
- Payne Brendan AI
- Peacock Sharon J
- Pearson Clare
- Perry Malorie
- Peto Timothy
- Pinckert Malte L
- Platt Steven
- Plimmer Amy
- Poplawski Radoslaw
- Potter Will
- Prakash Reenesh
- Prestwood Liam
- Price Anna
- Price Anna
- Price James
- Puethe Christoph
- Pybus Oliver
- Pybus Oliver G
- Pymont Hannah M
- Quail Mike
- Quick Joshua
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajatileka Shavanthi
- Rambaut Andrew
- Rambaut Andrew
- Ramsay Mary
- Randell Paul A
- Raviprakash Veena
- Raza Mohammad
- Resende Silva Paola C
- Rey Sara
- Rey Sara M
- Reynolds Nicola
- Richter Alex
- Robertson David L
- Robertson David L
- Robinson Esther
- Robinson Trevor I
- Robson Samuel C
- Rogers Hazel A
- Rooke Stefan
- Rowan Aileen
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Ryan Felicity
- Sambles Christine M
- Sang Fei
- Scarlett Garry P
- Schaefer Ulf
- Scher Emily
- Scott Carol
- Scott Garren
- Sethi Dheeraj K
- Shaaban Sharif
- Shah Divya
- Shah Rajiv
- Shah Rajiv N
- Shankar Giri
- Shaw Robert
- Shepherd James
- Shepherd James G
- Sheriff Nicola
- Shirley Lesley
- Signell Adrian W
- Sillitoe John
- Simpson David A
- Singer Joshua B
- Sivaprakasam Venkat
- Siveroni Igor
- Siveroni Igor
- Sloan Tim J
- Sluga Graciela
- Smith Christen
- Smith Colin P
- Smith Darren L
- Smith Nikki
- Smith Wendy
- Smollett Katherine L
- Snell Luke B
- Souster Emily
- Southgate Joel
- Southgate Joel
- Spellman Karla
- Spencer-Chapman Michael
- Sridhar Sushmita
- Stanley Rachael
- Stanton Thomas D
- Starinskij Igor
- Stark Richard
- Stockton Joanne
- Stuart Claire
- Studholme David J
- Swindells Emma
- Swingler Tracey
- Taha Yusri
- Tang Julian
- Taylor Ben EW
- Taylor Graham P
- Taylor Sarah
- Taylor-Joyce Grace
- Tedim Ana P
- Temperton Ben
- Templeton Kate E
- Thompson Thomas
- Thomson Emma C
- Thomson Emma C
- Thomson Nicholas M
- Thornton Alicia
- Thurston Scott
- Todd John A
- Tong Lily
- Tonkin-Hill Gerry
- Torok M Estee
- Trebes Amy
- Trotter Alexander J
- Tsoleridis Theocharis
- Tucker Rachel M
- Turtle Lance
- Tutill Helena J
- Underwood Anthony P
- Unnikrishnan Meera
- Vamos Edith E
- Vasylyeva Tetyana
- Vattipally Sreenu
- Vipond Ian B
- Volz Erik
- Volz Erik M
- Wain John
- Walsh Sarah
- Wang Dennis
- Wantoch Michelle
- Warne Ben
- Warwick-Dugdale Joanna
- Wastenge Elizabeth
- Watkins Joanne
- Watts Joanne
- Waugh Sheila
- Webber Mark A
- Weeks Sam
- Weldon Danni
- Whitehead Mark
- Williams Charlotte A
- Williams Chris
- Williams David
- Williams Rachel J
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A
- Willingham Iona
- Wilson Harry D
- Wise Emma
- Workman Trudy
- Wright Victoria
- Wyles Matthew
- Wyllie Sarah
- Yakovleva Anna
- Yasir Muhammad
- Yeats Corin A
- Yew Wen C
- Young Gregory R
- Young Jamie
- Yu Xiaoyu
- Zarebski Alex
- Publication venue
- Cell
- Publication date
- 01/09/2020
- Field of study
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike 614 variants, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the spike 614G variant have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant
Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes
- Author
- Aanensen David M.
- Abudahab Khalil
- Adams Alexander
- Adams Helen
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad SY.
- Aigrain Louise
- Alcolea-Medina Adela
- Alikhan Nabil-Fareed
- Allara Elias
- Amato Roberto
- Angyal Adrienn
- Annett Tara
- Aplin Stephen
- Ariani Cristina V.
- Asad Hibo
- Ash Amy
- Ashfield Paula
- Ashford Fiona
- Atkinson Laura
- Attwood Stephen W.
- Auckland Cressida
- Aydin Alp
- Baker David J.
- Baker Paul
- Balcazar Carlos E.
- Ball Jonathan
- Barrett Jeffrey C.
- Barrow Magdalena
- Barton Edward
- Bashton Matthew
- Bassett Andrew R.
- Batra Rahul
- Baxter Chris
- Bayzid Nadua
- Beaver Charlotte
- Beckett Angela H.
- Beckwith Shaun M.
- Bedford Luke
- Beer Robert
- Beggs Andrew
- Bellis Katherine L.
- Berry Louise
- Bertolusso Beatrice
- Best Angus
- Betteridge Emma
- Bibby David
- Bicknell Kelly
- Binns Debbie
- Birchley Alec
- Bird Paul W.
- Bishop Chloe
- Blacow Rachel
- Blakey Victoria
- Blane Beth
- Bolt Frances
- Bonfield James
- Bonner Stephen
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Boyd Olivia
- Bradley Declan T.
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgett Stephen
- Bronner Iraad F.
- Brooks Ellena
- Broos Alice
- Brown Julianne R.
- Bucca Giselda
- Buchan Sarah L.
- Buck David
- Bull Matthew
- Burns Phillipa J.
- Burton-Fanning Shirelle
- Byaruhanga Timothy
- Byott Matthew
- Campbell Sharon
- Carabelli Alessandro M.
- Cargill James S.
- Carlile Matthew
- Carvalho Sílvia F.
- Casey Anna
- Castigador Anibolina
- Catalan Jana
- Chalker Vicki
- Chaloner Nicola J.
- Chand Meera
- Chappell Joseph G.
- Charalampous Themoula
- Chatterton Wendy
- Chaudhry Yasmin
- Churcher Carol M.
- Clark Gemma
- Clarke Phillip
- Cogger Benjamin J.
- Cole Kevin
- Collins Jennifer
- Colquhoun Rachel
- Connor Thomas R.
- Cook Kate F.
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nicholas
- Cotic Marius
- Cotton S.
- Cotton Seb
- Cottrell Simon
- Coupland Lindsay
- Cox Alison
- Cox MacGregor
- Craine Noel
- Crawford Liam
- Cross Aidan
- Crown Matthew R.
- Crudgington Dorian
- Cumley Nicola
- Curran Martin D.
- Curran Tanya
- Cutino-Moguel Teresa
- da Silva Filipe Ana
- Dabrer Gavin
- Darby Alistair C.
- Davidson Rose K.
- Davies Alisha
- Davies Robert M.
- Davis Thomas
- de Angelis Daniela
- De Lacy Elen
- de Oliveira Martins Leonardo
- de Silva Thushan I.
- Debebe Johnny
- Delgado Callico Laia
- Denton-Smith Rebecca
- Dervisevic Samir
- Dewar R.
- Dewar Rebecca
- Dey Jayasree
- Dias Joana
- Dobie Donald
- Dorman Matthew J.
- Downing Fatima
- Driscoll Megan
- du Plessis Louis
- Duckworth Nichola
- Durham Jillian
- Eastick Kirstine
- Easton Lisa J.
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- El Bouzidi Kate
- Eldirdiri Sahar
- Ellaby Nicholas
- Elliott Scott
- Eltringham Gary
- Ensell Leah
- Erkiert Michelle J.
- Essex Sarah
- Evans Cariad
- Evans Johnathan M.
- Everson William
- Fairley Derek J.
- Fallon Karlie
- Fanaie Arezou
- Farr Ben W.
- Fearn Christopher
- Feltwell Theresa
- Ferguson Lynne
- Fina Laia
- Flaviani Flavia
- Fleming Vicki M.
- Forrest Sally
- Foster-Nyarko Ebenezer
- Foulkes Benjamin H.
- Foulser Luke
- Fragakis Mireille
- Frampton Dan
- Francois Sarah
- Fraser Christophe
- Freeman Timothy M.
- Fryer Helen
- Fuchs Marc
- Fuller William
- Gajee Kavitha
- Galai Katerina
- Gallagher Abbie
- Gallagher Eileen
- Gallagher Michael D.
- Gallis Marta
- Gaskin Amy
- Gatica-Wilcox Bree
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P.
- Gifford Laura
- Gilbert Lauren
- Girgis Sophia T.
- Glaysher Sharon
- Goldstein Emily J.
- Golubchik Tanya
- Gomes Andrea N.
- Gonçalves Sónia
- Goodwin Scott
- Goudarzi Salman
- Gourtovaia Marina
- Graham Clive
- Graham Lee
- Grant Paul R.
- Green Angie
- Green Luke R.
- Greenaway Jane
- Gregory Richard
- Guest Martyn
- Gunson Rory N.
- Gupta Ravi K.
- Gutierrez Bernardo
- Haas J.G.
- Haldenby Sam T.
- Hamilton William L.
- Hansford Samantha E.
- Haque Tanzina
- Harris Kathryn A.
- Harrison Ewan M.
- Harrison Ian
- Hart Jennifer
- Hartley John A.
- Harvey Matthew
- Harvey William T.
- Hassan-Ibrahim Mohammed O.
- Heaney Judith
- Helmer Thomas
- Henderson John H.
- Hesketh Andrew R.
- Hey Jessica
- Heyburn David
- Higginson Ellen E.
- Hill Jack D.
- Hill Verity
- Hilson Rachel A.
- Hilvers Ember
- Holden Matthew TG.
- Hollis Amy
- Holmes Alison H.
- Holmes Christopher W.
- Holmes Nadine
- Hopes Richard
- Hornsby Hailey R.
- Hosmillo Myra
- Houlihan Catherine
- Howson-Wells Hannah C.
- Hsu Sharon N.
- Hubb Jonathan
- Huckson Hannah
- Hughes Joseph
- Hughes Margaret
- Hughes Warwick
- Hutchings Stephanie
- Idle Giles
- Illingworth Chris J.
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Izuagbe Rhys
- Jackson Ben
- Jackson Chris
- Jackson David K.
- Jackson Kathryn A.
- Jackson Leigh M.
- Jahun Aminu S.
- James Keith
- James Victoria
- Jeanes Christopher
- Jeffries Aaron R.
- Jeremiah Sarah
- Jermy Andrew
- John Michaela
- Johnson Kate
- Johnson Rob
- Johnston Ian
- Jones Christopher R.
- Jones Hannah
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- Joseph Amelia
- Judges Sarah
- Kay Gemma L.
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- Keatley Jon-Paul
- Keeley Alexander J.
- Kele Beatrix
- Kenyon Anita
- Kermack Leanne M.
- Khakh Manjinder
- Kidd Stephen P.
- Killough Nicholas F.
- Kimuli Maimuna
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- Knight Bridget A.
- Koshy Cherian
- Kraemer Moritz UG.
- Kumziene-Summerhayes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Laing Kenneth G.
- Lampejo Temi
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- Le-Viet Thanh
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- Livett Rich
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- Ludden Catherine
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- Machin Nicholas W.
- MacIntyre-Cockett George
- Mack Andrew
- Macklin Ben
- Maclean Alasdair
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- Madona Pinglawathee
- Maes Mailis
- Maftei Laurentiu
- Mahanama Adhyana IK.
- Mahungu Tabitha W.
- Mair Daniel
- Maksimovic Joshua
- Malone Cassandra S.
- Maloney Daniel
- Manesis Nikos
- Manley Robin
- Mantzouratou Anna
- Marchbank Angela
- Mariappan Arun
- Markov Anna
- Martincorena Inigo
- Martinez Nunez Rocio T.
- Mather Alison E.
- Maxwell Patrick
- Mayhew Megan
- Mbisa Tamyo
- McCann Clare M.
- McCarthy Shane A.
- McCluggage Kathryn
- McClure Patrick C.
- McCrone J.T.
- McHugh M.P.
- McHugh Martin P.
- McKenna James P.
- McKerr Caoimhe
- McManus Georgina M.
- McMurray Claire
- McMurray Claire L.
- McNal Alan
- Meadows Lizzie
- Medd Nathan
- Megram Oliver
- Menegazzo Mirko
- Merrick Ian
- Michell Stephen L.
- Michelsen Michelle L.
- Mirfenderesky Mariyam
- Mirza Jeremy
- Miskelly Julia
- Moles-Garcia Emma
- Moll Robin J.
- Molnar Zoltan
- Monahan Irene M.
- Mondani Matteo
- Mookerjee Siddharth
- Moore Catherine
- Moore Christopher
- Moore Jonathan
- Moore Nathan
- Morcrette Helen
- Morgan Mari
- Morgan Sian
- Mori Matilde
- Morris Arthur
- Moses Samuel
- Mower Craig
- Muir Peter
- Mukaddas Afrida
- Munemo Florence
- Munn Robert
- Murray Abigail
- Murray Darren R.
- Murray Leanne J.
- Mutingwende Manasa
- Myers Richard
- Nastouli Eleni
- Nebbia Gaia
- Nelson Andrew
- Nelson Charlotte
- Nicholls Sam
- Nichols Jenna
- Nicodemi Roberto
- Nomikou Kyriaki
- O'Brien Sarah
- O'Grady Justin
- O'Toole Áine
- Odedra Mina
- Ohemeng-Kumi Natasha
- Oliver Karen
- Orton Richard J.
- Osman Husam
- Pacchiarini Nicole
- Padgett Debra
- Page Andrew J.
- Park Emily J.
- Park Naomi R.
- Parker Matthew D.
- Parmar Surendra
- Partridge David G.
- Pascall David
- Patel Amita
- Patel Bindi
- Paterson Steve
- Payne Brendan AI.
- Peacock Sharon J.
- Pearson Clare
- Pelosi Emanuela
- Percival Benita
- Perkins Jon
- Perry Malorie
- Pinckert Malte L.
- Platt Steven
- Podplomyk FD Olga
- Pohare Manoj
- Pond Marcus
- Pope Cassie F.
- Poplawski Radoslaw
- Powell Jessica
- Poyner Jennifer
- Prestwood Liam
- Price Anna
- Price James R.
- Prieto Jacqui A.
- Pritch David T.
- Prosolek Sophie J.
- Pugh Georgia
- Pusok Monika
- Pybus Oliver G.
- Pymont Hannah M.
- Quail Michael A.
- Quick Joshua
- Radulescu Clara
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajan Diana
- Rajatileka Shavanthi
- Ramadan Newara A.
- Rambaut Andrew
- Ramble John
- Randell Paul
- Randell Paul A.
- Ratcliffe Liz
- Raviprakash Veena
- Raza Mohammad
- Redshaw Nicholas M.
- Rey Sara
- Reynolds Nicola
- Richter Alex
- Robertson David L.
- Robinson Esther
- Robson Samuel C.
- Rogan Fiona
- Rooke Stefan
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Rushton Steven
- Saeed Kordo
- Samaraweera Buddhini
- Sambles Christine M.
- Sanderson Roy
- Sanderson Theo
- Sang Fei
- Sass Thea
- Scher Emily
- Scott Carol
- Scott Garren
- Sehmi Jasveen
- Shaaban Sharif
- Shah Divya
- Shaw Jessica
- Shelest Ekaterina
- Shepherd James G.
- Sheridan Liz A.
- Sheriff Nicola
- Shirley Lesley
- Sillitoe John
- Silviera Siona
- Simpson David A.
- Singh Aditi
- Singleton Dawn
- Skvortsov Timofey
- Sloan Tim J.
- Sluga Graciela
- Smith Colin P.
- Smith Darren L.
- Smith Ken
- Smith Kim S.
- Smith Louise
- Smith Nikki
- Smith Perminder
- Smollett Katherine L.
- Snell Luke B.
- Somassa Thomas
- Southgate Joel
- Spellman Karla
- Spencer Chapman Michael H.
- Spurgin Lewis G.
- Spyer Moira J.
- Stanley Rachael
- Stanley William
- Stanton Thomas D.
- Starinskij Igor
- Stockton Joanne
- Stonehouse Susanne
- Storey Nathaniel
- Studholme David J.
- Sudhanva Malur
- Swindells Emma
- Taha Yusri
- Tan Ngee Keong
- Tang Julian W.
- Tang Miao
- Taylor Ben EW.
- Taylor Joshua F.
- Taylor Sarah
- Temperton Ben
- Templeton K.
- Templeton Kate E.
- Thomas Claire
- Thomas-McEwen Peter MD.
- Thomson Emma C.
- Thomson Laura
- Thornton Alicia
- Thurston Scott AJ.
- Todd John A.
- Tomb Rachael
- Tong Lily
- Tonkin-Hill Gerry
- Tovar-Corona Jaime M.
- Trebes Amy
- Trotter Alexander J.
- Tsatsani Ioulia
- Turnbull Robyn
- Twohig Katherine A.
- Umpleby Helen
- Underwood Anthony P.
- Vamos Edith E.
- Vasylyeva Tetyana I.
- Vattipally Sreenu
- Vernet Gabrielle
- Vipond Barry B.
- Volz Erik M.
- Walsh Sarah
- Wang Dennis
- Warne Ben
- Warwick-Dugdale Joanna
- Wastnedge Elizabeth
- Watkins Joanne
- Watson DipHE Louisa K.
- Waugh Sheila
- Webster Hermione J.
- Weldon Danni
- Westwick Elaine
- Whalley Thomas
- Wheeler Helen
- Whitehead Mark
- Whiteley Max
- Whitwham Andrew
- Wierzbicki Claudia
- Willford Nicholas J.
- Williams Catryn
- Williams Charlotte A.
- Williams Cheryl
- Williams Chris
- Williams Lesley-Anne
- Williams Rachel J.
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A.
- Wilson-Davies Eleri
- Witele Eric
- Withell Karen T.
- Witney Adam A.
- Wolverson Paige
- Wong Nick
- Workma Trudy
- Wright Derek W.
- Wright Victoria
- Wyatt Tim
- Wyllie Sarah
- Xu-McCrae Li
- Yavus Mehmet
- Yaze Geraldine
- Yeats Corin A.
- Yebra Gonzalo
- Yew Wen C.
- Young Gregory R.
- Young Jamie
- Zarebski Alex E.
- Zhang Peijun
- Publication venue
- 'Elsevier BV'
- Publication date
- 09/03/2023
- Field of study
Background
The first epidemic wave of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Scotland resulted in high case numbers and mortality in care homes. In Lothian, over one-third of care homes reported an outbreak, while there was limited testing of hospital patients discharged to care homes.
Aim
To investigate patients discharged from hospitals as a source of SARS-CoV-2 introduction into care homes during the first epidemic wave.
Methods
A clinical review was performed for all patients discharges from hospitals to care homes from 1st March 2020 to 31st May 2020. Episodes were ruled out based on coronavirus disease 2019 (COVID-19) test history, clinical assessment at discharge, whole-genome sequencing (WGS) data and an infectious period of 14 days. Clinical samples were processed for WGS, and consensus genomes generated were used for analysis using Cluster Investigation and Virus Epidemiological Tool software. Patient timelines were obtained using electronic hospital records.
Findings
In total, 787 patients discharged from hospitals to care homes were identified. Of these, 776 (99%) were ruled out for subsequent introduction of SARS-CoV-2 into care homes. However, for 10 episodes, the results were inconclusive as there was low genomic diversity in consensus genomes or no sequencing data were available. Only one discharge episode had a genomic, time and location link to positive cases during hospital admission, leading to 10 positive cases in their care home.
Conclusion
The majority of patients discharged from hospitals were ruled out for introduction of SARS-CoV-2 into care homes, highlighting the importance of screening all new admissions when faced with a novel emerging virus and no available vaccine
Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study
- Author
- Aanensen David M
- Abudahab Khalil
- Acheson Erwan
- Adams Alexander
- Adams Helen
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad S Y
- Aigrain Louise
- Alam Mohammad T.
- Alcolea-Medina Adela
- Alderton Alex
- Alikhan Nabil-Fareed
- Allara Elias
- Amato Roberto
- Andersson Monique
- Angyal Adrienn
- Antonelli Michela
- Aranday-Cortes Elihu
- Ariani Cristina V
- Asad Hibo
- Asamaphan Patawee
- Ash Amy
- Ashcroft Fiona
- Atkinson Laura
- Attwood Stephen W
- Auckland Cressida
- Awan Ali R
- Aydin Alp
- Baker David J
- Baker Paul
- Balcazar Carlos E
- Ball Jonathan
- Barrett Jeff
- Barton Edward
- Bashton Matthew
- Bassett Andrew R
- Batra Rahul
- Baxter Laura
- Bayzid Nadua
- Beale Mathew A
- Beaver Charlotte
- Beckett Angela H
- Bedford Luke
- Beer Robert
- Beggs Andrew
- Bellis Katherine L
- Berry Lisa
- Berry Louise
- Best Angus
- Betancor Gilberto
- Betteridge Emma
- Bewshea Claire M
- Bibby David
- Bicknell Kelly
- Birchley Alec
- Bird Paul
- Bishop Chloe
- Blacow Rachel
- Blakey Victoria
- Blane Beth
- Bolt Frances
- Bonfield James
- Bonner Stephen
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Boyd Olivia
- BoYes John
- Bradley Amanda
- Bradley Declan T
- Bradshaw Daniel
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgewater Hannah E.
- Bronner Iraad F
- Brooks Ellena
- Broos Alice
- Brown Julianne Rose
- Brown Paul E
- Brown Rebecca
- Bucca Giselda
- Buck David
- Bull Matthew
- Burton-Fanning Shirelle
- Campbell Sharon
- Canas Liane S
- Capdevila Joan
- Carabelli Alessandro M
- Carden Holli
- Carlile Matthew
- Carmichael Stephen N
- Casey Anna
- Cerda Alberto C
- Chalker Vicki
- Chan Andrew T
- Chand Meera
- Chapman Michael R
- Chappell Joseph G
- Charalampous Themoula
- Chatterton Wendy
- Chaudhry Yasmin
- Chauhan Anoop J
- Cheng Jeffrey K.J.
- Churcher Carol M
- Clark Gemma
- Cogger Benjamin J
- Coll Francesc
- Collins Jennifer
- Connor Thomas R
- Constantinidou Chrystala
- Cook Kate
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nick
- Cotic Marius
- Cottrell Simon
- Coupland Lindsay
- Cowell Angela
- Cox Alison
- Craine Noel
- Crawford Liam
- Cronin Michelle
- Crook Derrick
- Cumley Nicola
- Curran Martin D
- Curran Tanya
- da Silva Filipe Ana
- Dabrera Gavin
- Dadrah Ashok
- Danesh John
- Darby Alistair C
- Davidson Rose K
- Davies Alisha
- Davies Robert
- Davis Thomas
- de Cesare Mariateresa
- De Lacy Elen
- de Oliveira Martins Leonardo
- de Silva Thushan I
- Debebe Johnny
- Dent Hannah
- Dervisevic Samir
- Dewar Rebecca
- Dias Joana
- Dorman Matthew J
- Downing Fatima
- Drew David A
- Drury Eleanor
- du Plessis Louis
- Duckworth Nichola
- Durham Jillian
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- Eldirdiri Sahar
- Ellaby Nicholas
- Ellard Sian
- Elliott Scott
- Eltringham Gary
- Ensell Leah
- Escalera Zamudio Marina
- Essex Sarah
- Evans Cariad
- Evans Johnathan M
- Eyre David
- Fairley Derek J
- Fallon Karlie
- Farbos Audrey
- Farr Ben W
- Fearn Christopher
- Fenton Melisa Louise
- Fina Laia
- Fisher Chloe L
- Flaviani Flavia
- Fleming Vicki M
- Forrest Sally
- Foulser Luke
- Francois Sarah
- Fraser Christophe
- Freeman Timothy M
- Frost Lucy R.
- Fuller William
- Galai Katerina
- Gallagher Eileen
- Gallagher Michael D
- Gallis Marta
- Gaskin Amy
- Gatica-Wilcox Bree
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P
- Gifford Laura
- Gilbert Lauren
- Gill Harmeet K
- Girgis Sophia T
- Glaysher Sharon
- Golubchik Tanya
- Goncalves Sonia
- Goodfellow Ian G
- Goodwin Scott
- Goudarzi Salman
- Gourtovaia Marina
- Graham Clive
- Graham Lee
- Graham Mark S
- Grammatopoulos Dimitris
- Green Angie
- Green Luke R
- Greenaway Jane
- Gregory Richard
- Groves Danielle C
- Groves Natalie
- Guest Martyn
- Gulliver Huw
- Gunson Rory N
- Gupta Ravi Kumar
- Gutierrez Bernardo
- Hadjirin Nazreen F
- Haldenby Sam T
- Hale Antony D
- Hall Grant
- Halstead Fenella
- Hamilton William L
- Hammers Alexander
- Haque Tanzina
- Harper Katherine L
- Harris Kathryn Ann
- Harrison Ewan M
- Harrison Ian
- Harrison James W
- Hart Jennifer
- Hartley John A
- Hartman Hassan
- Hassan-Ibrahim Mohammed O
- Heaney Judith
- Helmer Thomas
- Hesketh Andrew R
- Heyburn David
- Higginson Ellen E
- Hill Verity
- Hilvers Ember
- Hiscox Julian A
- Hogsden Wendy
- Holden Matthew T.G.
- Holmes Alison
- Holmes Christopher
- Holmes Nadine
- Hopes Richard
- Hosmillo Myra
- Howe Robin
- Howson-Wells Hannah C
- Hu Christina
- Hubb Jonathan
- Hughes Joseph
- Hughes Margaret
- Hutchings Stephanie
- Illingworth Chris J
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Jackson Chris
- Jackson David K
- Jackson Kathryn A
- Jahun Aminu S
- James Keith
- Jamrozy Dorota
- Jannoo Riaz
- Jeffries Aaron R
- Jeremiah Sarah
- Jesudason Natasha G
- John Michaela
- Johnson Kate
- Johnson Natasha
- Johnson Rob
- Johnston Ian
- Jones Carl
- Jones Christopher R
- Jones Hannah
- Jones Katie
- Jones Rachel
- Jones Sophie
- Jorgensen David
- Joseph Amelia
- Justice Anita
- Kane Leanne
- Karamani Angeliki
- Kay Gemma L
- Kay Sally
- Keatley Jon-Paul
- Keeley Alexander J
- Kenyon Anita
- Kermack Leanne M
- Khakh Manjinder
- Kidd Stephen
- Kitchen Christine
- Kläser Kerstin
- Knight Bridget A
- Koshy Cherian
- Kraemer Moritz UG
- Kristiansen Mark
- Kumziene-SummerhaYes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Langford Cordelia F
- Lawniczak Mara
- Le-Viet Thanh
- Ledesma Juan
- Lee David
- Lee Jack CD
- Leek Danielle
- Lensing Stefanie V
- Leonard Steven
- Letchford Laura
- Levene Nick
- Levett Lisa J
- Lewis Kevin
- Li Kathy K
- Liddle Jennifier
- Liggett Steven
- Lindsey Benjamin B
- Lister Michelle M
- Livett Rich
- Lloyd Allyson
- Lo Stephanie
- Loman Nicholas J
- Loose Matthew W
- Louka Stavroula F
- Loveson Katie F
- Lowe Hannah
- Lowe Helen L
- Lucaci Anita O
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A
- Macfarlane-Smith Louissa R
- Machin Nicholas W
- MacIntyre-Cockett George
- Maclean Alasdair
- Madona Pinglawathee
- Maes Mailis
- Mahanama Adhyana I.K
- Mahungu Tabitha W
- Mair Daniel
- Maksimovic Joshua
- Makunin Alex
- Malone Cassandra S
- Manesis Nikos
- Manley Robin
- Manso Carmen
- Marchbank Angela
- Martincorena Inigo
- Martinez Nunez Rocio T
- Masoli Jane AH
- Mason Jenifer
- Mather Alison E
- May Anna
- Mayhew Megan
- Mbisa Tamyo
- McCann Clare
- McCarthy Shane
- McCluggage Kathryn
- McClure Patrick C
- McGuigan Samantha
- McHugh Martin P
- McKenna James P
- McKerr Caoimhe
- McManus Georgina M
- McMurray Claire
- McNally Alan
- Meader Emma J
- Meadows Lizzie
- Megram Oliver
- Menegazzo Mirko
- Merrick Ian
- Merrill Tammy V
- Miah Shahjahan
- Michell Stephen L
- Michelsen Michelle L
- Mirza Jeremy
- Modat Marc
- Moles-Garcia Emma
- Moll Robin J
- Mollett Guy
- Molnar Zoltan
- Molteni Erika
- Monaghan Lynn
- Mookerjee Siddharth
- Moore Catherine
- Moore Christopher
- Moore Jonathan
- Moore Nathan
- Morgan Mari
- Morgan Sian
- Mori Matilde
- Moses Samuel
- Muir Peter
- Munn Robert
- Murray Benjamin
- Myers Richard
- Nascimento Fabricia F.
- Nebbia Gaia
- Nelson Andrew
- Nelson Charlotte
- Nelson Rachel
- Nguyen Long H
- Nicholls Sam
- Nichols Jenna
- Nickbakhsh Seema
- Niebel Marc O
- Nomikou Kyriaki
- O'Brien Sarah
- O'Grady Justin
- O'Toole Elaine
- O'Toole Áine
- Oliver Karen
- Orton Richard J
- Osman Husam
- Ott Sascha
- Ourselin Sebastien
- Pacchiarini Nicole
- Padgett Debra
- Page Andrew J
- Palmer Sophie
- Palmer Steve
- Pandey Sarojini
- Park Naomi R
- Parker Matthew D
- Parmar Surendra
- Parsons Paul J
- Partridge David G
- Patel Amita
- Patel Minal
- Patel Vineet
- Paterson Steve
- Paul Hannah
- Payne Brendan AI
- Peacock Sharon J
- Pearson Clare
- Pelosi Emanuela
- Percival Benita
- Perry Malorie
- Peto Timothy
- Pinckert Malte L
- Platt Steven
- Plimmer Amy
- Polidori Lorenzo
- Poplawski Radoslaw
- Prestwood Liam
- Price Anna
- Price James
- Prieto Jacqui A
- Puethe Christoph
- Pusok Monika
- Pybus Oliver G
- Pymont Hannah M
- Quail Michael A
- Quick Joshua
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajan Diana
- Rajatileka Shavanthi
- Rambaut Andrew
- Ramsay Mary
- Randell Paul Anthony
- Ratcliffe Liz
- Raviprakash Veena
- Raza Mohammad
- Redshaw Nicholas M
- Rey Sara
- Reynolds Nicola
- Richter Alex
- Robertson David L
- Robinson Esther
- Robinson Trevor I
- Robson Samuel C
- Rooke Stefan
- Rowan Aileen
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Rushton Steven
- Saeed Kordo
- Saluja Tranprit
- Samaraweera Buddhini
- Sambles Christine M
- Sang Fei
- Scarlett Garry P
- Schaefer Ulf
- Scott Carol
- Scott Garren
- Selvachandran Somesh
- Shaaban Sharif
- Shah Divya
- Shah Rajiv N
- Shankar Giri
- Shepherd James G
- Sheriff Nicola
- Shirley Lesley
- Signell Adrian W
- Sillitoe John
- Silveira Siona
- Simpson David A
- Singer Joshua B
- Sivaprakasam Venkat
- Siveroni Igor
- Sloan Tim J
- Sluga Graciela
- Smith Colin P
- Smith Darren
- Smith Kim S
- Smith Louise
- Smith Nikki
- Smith Wendy
- Smollett Katherine L
- Snell Luke B
- Southgate Joel
- Spector Tim D
- Spellman Karla
- Spencer Chapman Michael H
- Sridhar Sushmita
- Stanley Rachael
- Stanton Thomas D
- Starinskij Igor
- Stark Richard
- Steves Claire J
- Stockton Joanne
- Stonehouse Susanne
- Storey Nathaniel
- Studholme David J
- Sudre Carole H
- Swindells Emma
- Symmonds Amanda
- Taha Yusri
- Tang Julian
- Taylor Ben EW
- Taylor Graham P
- Taylor Sarah
- Taylor-Joyce Grace
- Temperton Ben
- Templeton Kate E
- Thompson Thomas
- Thomson Emma C
- Thornton Alicia
- Thurston Scott AJ
- Todd John A
- Tong Lily
- Tonkin-Hill Gerry
- Torok M. Estee
- Tovar-Corona Jaime M
- Trebes Amy
- Trotter Alexander J
- Tsoleridis Theocharis
- Tucker Rachel M
- Turtle Lance
- Twohig Katherine A
- Underwood Anthony P
- Unnikrishnan Meera
- Vamos Edith E
- Varsavsky Thomas
- Vasylyeva Tetyana I
- Vattipally Sreenu
- Vernet Gabrielle
- Vipond Ian B
- Volz Erik M
- Walsh Sarah
- Wang Dennis
- Wantoch Michelle
- Warne Ben
- Warwick-Dugdale Joanna
- Wastenge Elizabeth
- Watkins Joanne
- Watts Joanne
- Waugh Sheila
- Webster Hermione J
- Weldon Danni
- Westhorpe Adam P
- Whitehead Mark
- Whiteley Max
- Whitwham Andrew
- Wierzbicki Claudia
- Williams Charlotte A
- Williams Chris
- Williams David
- Williams Lesley-Anne
- Williams Rachel J
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A
- Willingham Iona
- Wilson Harry D
- Wilson Rebekah E
- Wilson-Davies Eleri
- Wise Emma
- Witele Eric
- Wolf Jonathan
- Workman Trudy
- Wright Victoria
- Wyatt Tim
- Wyles Matthew
- Wyllie Sarah
- Xu-McCrae Li
- Yeats Corin A
- Yew Wen C
- Young Greg
- Young Jamie
- Zarebski Alex E
- Zhang Peijun
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/05/2021
- Field of study
Background
The SARS-CoV-2 variant B.1.1.7 was first identified in December, 2020, in England. We aimed to investigate whether increases in the proportion of infections with this variant are associated with differences in symptoms or disease course, reinfection rates, or transmissibility.
Methods
We did an ecological study to examine the association between the regional proportion of infections with the SARS-CoV-2 B.1.1.7 variant and reported symptoms, disease course, rates of reinfection, and transmissibility. Data on types and duration of symptoms were obtained from longitudinal reports from users of the COVID Symptom Study app who reported a positive test for COVID-19 between Sept 28 and Dec 27, 2020 (during which the prevalence of B.1.1.7 increased most notably in parts of the UK). From this dataset, we also estimated the frequency of possible reinfection, defined as the presence of two reported positive tests separated by more than 90 days with a period of reporting no symptoms for more than 7 days before the second positive test. The proportion of SARS-CoV-2 infections with the B.1.1.7 variant across the UK was estimated with use of genomic data from the COVID-19 Genomics UK Consortium and data from Public Health England on spike-gene target failure (a non-specific indicator of the B.1.1.7 variant) in community cases in England. We used linear regression to examine the association between reported symptoms and proportion of B.1.1.7. We assessed the Spearman correlation between the proportion of B.1.1.7 cases and number of reinfections over time, and between the number of positive tests and reinfections. We estimated incidence for B.1.1.7 and previous variants, and compared the effective reproduction number, Rt, for the two incidence estimates.
Findings
From Sept 28 to Dec 27, 2020, positive COVID-19 tests were reported by 36 920 COVID Symptom Study app users whose region was known and who reported as healthy on app sign-up. We found no changes in reported symptoms or disease duration associated with B.1.1.7. For the same period, possible reinfections were identified in 249 (0·7% [95% CI 0·6–0·8]) of 36 509 app users who reported a positive swab test before Oct 1, 2020, but there was no evidence that the frequency of reinfections was higher for the B.1.1.7 variant than for pre-existing variants. Reinfection occurrences were more positively correlated with the overall regional rise in cases (Spearman correlation 0·56–0·69 for South East, London, and East of England) than with the regional increase in the proportion of infections with the B.1.1.7 variant (Spearman correlation 0·38–0·56 in the same regions), suggesting B.1.1.7 does not substantially alter the risk of reinfection. We found a multiplicative increase in the Rt of B.1.1.7 by a factor of 1·35 (95% CI 1·02–1·69) relative to pre-existing variants. However, Rt fell below 1 during regional and national lockdowns, even in regions with high proportions of infections with the B.1.1.7 variant.
Interpretation
The lack of change in symptoms identified in this study indicates that existing testing and surveillance infrastructure do not need to change specifically for the B.1.1.7 variant. In addition, given that there was no apparent increase in the reinfection rate, vaccines are likely to remain effective against the B.1.1.7 variant.
Funding
Zoe Global, Department of Health (UK), Wellcome Trust, Engineering and Physical Sciences Research Council (UK), National Institute for Health Research (UK), Medical Research Council (UK), Alzheimer's Society
Ethnic Issues
- Author
- A Bibb
- A Kleinman
- A Stepick
- AF Scott
- AL Hall
- B Bloch
- B Tedlock
- BL Bade
- C Nagengast
- C Zabin
- C Zabin
- CB Burke
- D Mcgill
- D Runsten
- EW Randell-David
- FNU Griffin
- H Weidman
- J Giordano
- J Grieshop
- J Schreiber
- JA Sproles
- JC Cobb
- JW Flynt
- KLS Mcvea
- L Mata
- L Stephen
- LF Snow
- M Kearney
- M Laguerre
- MA Miralles
- MB Civan
- MS Frank
- N Vlach
- NE Schoenberg
- R Trotter
- RD Baer
- RD Baer
- RD Baer
- S Cosminsky
- S Mydans
- SE Stans
- SM Lassiter
- T de Paula
- T Freedman
- WW Dressler
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2001
- Field of study
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity
- Author
- Aanensen David M
- Abudahab Khalil
- Acheson Erwan
- Adams Alexander
- Adams Helen
- Adriaenssens Evelien M
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad SY
- Alam Mohammad T
- Alcolea-Medina Adela
- Alderton Alex
- Alikhan Nabil-Fareed
- Allan John
- Allara Elias
- Amato Roberto
- Andersson Monique
- Angyal Adrienn
- Aranday-Cortes Elihu
- Ariani Cristina
- Asad Hibo
- Asamaphan Patawee
- Ashworth Jordan
- Atkinson Laura
- Attwood Stephen
- Auckland Cressida
- Awan Ali R
- Aydin Alp
- Baker David J
- Baker Paul
- Balcazar Carlos E
- Ball Jonathan
- Barton Edward
- Bashton Matthew
- Batra Rahul
- Baxter Laura
- Beale Mathew A
- Beaver Charlotte
- Beckett Angela
- Beer Robert
- Beggs Andrew
- Bell Andrew
- Bellis Katherine L
- Berger Duncan J
- Berriman Matt
- Berry Lisa
- Berry Louise
- Betancor Gilberto
- Betteridge Emma
- Bewshea Claire M
- Bibby David
- Bicknell Kelly
- Birchley Alec
- Bird Paul
- Bishop Chloe
- Blane Beth
- Bolt Frances
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Boyd Olivia
- Boyes John
- Bradley Declan T
- Bradshaw Daniel
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgewater Hannah E
- Brooks Tony T
- Broos Alice
- Brown Julianne Rose
- Brown Paul E
- Brown Rebecca
- Brunker Kirstyn
- Bucca Giselda
- Buck David
- Buddenborg Sarah K
- Bull Matthew
- Bull Matthew
- Burton-Fanning Shirelle
- Butcher Ethan
- Caddy Sarah L
- Caller Laura G
- Campbell Sharon
- Carlile Matthew
- Carmichael Stephen N
- Casey Anna
- Castellano Sergi
- Chalker Vicki
- Chand Meera
- Chapman Michael R
- Chappell Joseph G
- Charalampous Themoula
- Charles Ian G
- Chaudhry Yasmin
- Chauhan Anoop J
- Cheng Jeffrey KJ
- Churcher Carol M
- Clark Gemma
- Coll Francesc
- Collins Jennifer
- Colquhoun Rachel
- Colquhoun Rachel M
- Connor Thomas R
- Connor Thomas R
- Constantinidou Chrystala
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nicholas
- Cortes Nick
- Cottrell Simon
- Coupland Lindsay J
- Cowell Angela
- Cox Alison
- Craine Noel
- Cronin Michelle
- Crooke Derrick
- Curran Martin D
- Curran Tanya
- da Silva Filipe Ana
- da Silva Filipe Ana
- Dabrera Gavin
- Danesh John
- Darby Alistair C
- Davidson Rose K
- Davies Alisha
- Davis Thomas
- de Cesare Mariateresa
- De Lacy Elen
- de Oliveira Martins Leonardo
- de Silva Thushan I
- Debebe Johnny
- Dervisevic Samir
- Dewar Rebecca
- Dias Joana
- Diaz Maria
- Dibling Thomas
- Dorman Matthew J
- Downing Fatima
- Drury Eleanor
- du Plessis Louis
- Duckworth Nichola
- Dyal Patricia L
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- Eldirdiri Sahar
- Ellaby Nicholas
- Ellard Sian
- Elliott Scott
- Eltringham Gary
- Elumogo Ngozi
- Essex Sarah
- Evans Cariad
- Evans Johnathan M
- Eyre David
- Fairley Derek J
- Fallon Karlie
- Farbos Audrey
- Farr Ben
- Feltwell Theresa
- Fina Laia
- Findlay Jacqueline
- Fisher Chloe L
- Fleming Vicki M
- Forrest Leysa M
- Forrest Sally
- Foulser Luke
- Francois Sarah
- Fraser Christophe
- Freeman Timothy M
- Frost Lucy R
- Fuller William
- Gallagher Eileen
- Gallagher Michael D
- Garcia-Casado Maria V
- Gaskin Amy
- Gatica-Wilcox Bree
- Gavriil Artemis
- Geidelberg Lily
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P
- Gifford Laura
- Gilbert Lauren
- Gill Harmeet K
- Gilroy Rachel AJ
- Girgis Sophia T
- Glaysher Sharon
- Golubchik Tanya
- Goncalves Sonia
- Goodfellow Ian
- Goodfellow Ian G
- Goodwin Scott
- Graham Clive
- Graham Lee
- Gramatopoulos Dimitris
- Green Angie
- Green Luke R
- Greenaway Jane
- Gregory Richard
- Griffith Luke
- Groves Danielle C
- Groves Natalie
- Guest Martyn
- Gulliver Huw
- Gutierrez Ana Victoria
- Hadjirin Nazreen F
- Haldenby Sam T
- Hale Antony D
- Hall Grant
- Halstead Fenella
- Hamilton William L
- Haque Tanzina
- Harper Katherine L
- Harris Kathryn Ann
- Harrison Ewan M
- Harrison Ian
- Harrison James W
- Hartman Hassan
- Hattersley Andrew
- Heaney Judith
- Helmer Thomas
- Hesketh Andrew R
- Heyburn David
- Higginson Ellen E
- Hill Verity
- Hill Verity
- Hilvers Ember
- Hiscox Julian A
- Holden Matthew TG
- Holmes Alison
- Holmes Christopher
- Holmes Nadine
- Hoosdally Sarah
- Hopes Richard
- Hosmillo Myra
- Houldcroft Charlotte J
- Howe Robin
- Howson-Wells Hannah C
- Hubb Jonathan
- Hughes Joseph
- Hughes Margaret
- Hunter Adam D
- Hutchings Stephanie
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Jackson Ben
- Jackson Ben
- Jackson David A
- Jackson David K
- Jackson Kathryn A
- Jahun Aminu S
- James Keith
- Jamrozy Dorota
- Jarrett Ruth
- Jeffries Aaron R
- Jesudason Natasha
- Jesudason Natasha G
- John Michaela
- Johnson Kate
- Johnson Natasha
- Johnson Rob
- Johnson Robert
- Johnston Ian
- Jones Hannah
- Jones Katie
- Jones Rachel
- Jones Sophie
- Jorgensen David
- Jorgensen David
- Joseph Amelia
- Justice Anita
- Kane Leanne
- Kay Gemma L
- Kay Sally
- Keatley Jon-Paul
- Keeley Alexander J
- Kenyon Anita
- Kermack Leanne M
- Khakh Manjinder
- Khokhar Fahad A
- Kidd Stephen
- Kingsley Robert A
- Kitchen Christine
- Knight Bridget A
- Kolyva Anastasia
- Koshy Cherian
- Kraemer Moritz
- Kristiansen Mark
- Kumziene-Summerhayes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Langford Cordelia
- Lawniczak Mara
- Le-Viet Thanh
- Lee David
- Lee Jack CD
- Letchford Laura
- Levene Nick
- Levett Lisa J
- Li Kathy
- Li Kathy K
- Liggett Steven
- Lindsey Benjamin B
- Lister Michelle M
- Livett Rich
- Lloyd Allyson
- Lo Stephanie
- Loh Joshua
- Loman Nicholas J
- Loman Nicholas J
- Loose Matthew W
- Loveson Katie F
- Lowe Hannah
- Lucaci Anita O
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A
- Macfarlane-Smith Louissa R
- Machin Nicholas W
- MacIntyre-Cockett George
- Madona Pinglawathee
- Maes Mailis
- Mahungu Tabitha W
- Mair Daniel
- Maksimovic Joshua
- Manesis Nikos
- Manley Robin
- Manso Carmen
- Marchbank Angela
- Martincorena Inigo
- Martinez-Nunez Rocio T
- Masoli Jane AH
- Mason Jenifer
- Mather Alison E
- Mbisa Tamyo
- McCluggage Kathryn
- McClure Patrick C
- McCrone John T
- McCrone JT
- McGuigan Samantha
- McHugh Martin P
- McKenna James P
- McKerr Caoimhe
- McMinn Liz
- McMurray Claire
- Meader Emma J
- Meadows Lizzie
- Menegazzo Mirko
- Meredith Luke W
- Merrick Ian
- Mestek-Boukhibar Lamia
- Miah Shahjahan
- Michell Stephen L
- Michelsen Michelle L
- Molnar Zoltan
- Monaghan Lynn
- Mookerjee Siddharth
- Moore Catherine
- Moore Catrin
- Moore Christopher
- Moore Nathan
- Morgan Mari
- Morgan Sian
- Mori Matilde
- Moses Samuel
- Muir Peter
- Munn Robert
- Myers Richard
- Nascimento Fabricia F
- Nascimento Fabricia F
- Naydenova Plamena
- Neaverson Alexandra S
- Nebbia Gaia
- Nelson Andrew
- Nelson Charlotte
- Nelson Rachel
- Nicholls Sam
- Nicholls Samuel M
- Nichols Jenna
- Niebel Marc O
- Niola Paola
- Nomikou Kyriaki
- O'Toole Elaine
- O'Toole Áine
- Orton Richard J
- Osman Husam
- Ott Sascha
- O’Grady Justin
- O’Toole Áine
- Pacchiarini Nicole
- Pacchiarini Nicole
- Padgett Debra
- Page Andrew J
- Palmer Sophie
- Palmer Steve
- Panchbhaya Yasmin N
- Pandey Sarojini
- Park Naomi
- Parker Matthew D
- Parmar Surendra
- Parr Yasmin A
- Parsons Paul J
- Partridge David G
- Pascall David J
- Patel Gaurang
- Patel Minal
- Patel Vineet
- Paterson Steve
- Payne Brendan AI
- Peacock Sharon J
- Pearson Clare
- Perry Malorie
- Peto Timothy
- Pinckert Malte L
- Platt Steven
- Plimmer Amy
- Poplawski Radoslaw
- Potter Will
- Prakash Reenesh
- Prestwood Liam
- Price Anna
- Price Anna
- Price James
- Puethe Christoph
- Pybus Oliver
- Pybus Oliver G
- Pymont Hannah M
- Quail Mike
- Quick Joshua
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajatileka Shavanthi
- Rambaut Andrew
- Rambaut Andrew
- Ramsay Mary
- Randell Paul A
- Raviprakash Veena
- Raza Mohammad
- Resende Silva Paola C
- Rey Sara
- Rey Sara M
- Reynolds Nicola
- Richter Alex
- Robertson David L
- Robertson David L
- Robinson Esther
- Robinson Trevor I
- Robson Samuel C
- Rogers Hazel A
- Rooke Stefan
- Rowan Aileen
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Ryan Felicity
- Sambles Christine M
- Sang Fei
- Scarlett Garry P
- Schaefer Ulf
- Scher Emily
- Scott Carol
- Scott Garren
- Sethi Dheeraj K
- Shaaban Sharif
- Shah Divya
- Shah Rajiv
- Shah Rajiv N
- Shankar Giri
- Shaw Robert
- Shepherd James
- Shepherd James G
- Sheriff Nicola
- Shirley Lesley
- Signell Adrian W
- Sillitoe John
- Simpson David A
- Singer Joshua B
- Sivaprakasam Venkat
- Siveroni Igor
- Siveroni Igor
- Sloan Tim J
- Sluga Graciela
- Smith Christen
- Smith Colin P
- Smith Darren L
- Smith Nikki
- Smith Wendy
- Smollett Katherine L
- Snell Luke B
- Souster Emily
- Southgate Joel
- Southgate Joel
- Spellman Karla
- Spencer-Chapman Michael
- Sridhar Sushmita
- Stanley Rachael
- Stanton Thomas D
- Starinskij Igor
- Stark Richard
- Stockton Joanne
- Stuart Claire
- Studholme David J
- Swindells Emma
- Swingler Tracey
- Taha Yusri
- Tang Julian
- Taylor Ben EW
- Taylor Graham P
- Taylor Sarah
- Taylor-Joyce Grace
- Tedim Ana P
- Temperton Ben
- Templeton Kate E
- Thompson Thomas
- Thomson Emma C
- Thomson Emma C
- Thomson Nicholas M
- Thornton Alicia
- Thurston Scott
- Todd John A
- Tong Lily
- Tonkin-Hill Gerry
- Torok M Estee
- Trebes Amy
- Trotter Alexander J
- Tsoleridis Theocharis
- Tucker Rachel M
- Turtle Lance
- Tutill Helena J
- Underwood Anthony P
- Unnikrishnan Meera
- Vamos Edith E
- Vasylyeva Tetyana
- Vattipally Sreenu
- Vipond Ian B
- Volz Erik
- Volz Erik M
- Wain John
- Walsh Sarah
- Wang Dennis
- Wantoch Michelle
- Warne Ben
- Warwick-Dugdale Joanna
- Wastenge Elizabeth
- Watkins Joanne
- Watts Joanne
- Waugh Sheila
- Webber Mark A
- Weeks Sam
- Weldon Danni
- Whitehead Mark
- Williams Charlotte A
- Williams Chris
- Williams David
- Williams Rachel J
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A
- Willingham Iona
- Wilson Harry D
- Wise Emma
- Workman Trudy
- Wright Victoria
- Wyles Matthew
- Wyllie Sarah
- Yakovleva Anna
- Yasir Muhammad
- Yeats Corin A
- Yew Wen C
- Young Gregory R
- Young Jamie
- Yu Xiaoyu
- Zarebski Alex
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike 614 variants, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the spike 614G variant have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning
- Author
- Aanensen David M
- Abudahab Khalil
- Adams Alexander
- Adams Helen
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad SY
- Aigrain Louise
- Alcolea-Medina Adela
- Alikhan Nabil-Fareed
- Allara Elias
- Amato Roberto
- Angyal Adrienn
- Annett Tara
- Aplin Stephen
- Ariani Cristina V
- Asad Hibo
- Ash Amy
- Ashfield Paula
- Ashford Fiona
- Atkinson Laura
- Attwood Stephen W
- Auckland Cressida
- Aydin Alp
- Baker David J
- Baker Paul
- Balcazar Carlos E
- Ball Jonathan
- Barrett Jeffrey C
- Barrow Magdalena
- Barton Edward
- Bashton Matthew
- Bassett Andrew R
- Batra Rahul
- Baxter Chris
- Bayzid Nadua
- Beaver Charlotte
- Beckett Angela H
- Beckwith Shaun M
- Bedford Luke
- Beer Robert
- Beggs Andrew
- Bellis Katherine L
- Berry Louise
- Bertolusso Beatrice
- Best Angus
- Betteridge Emma
- Bibby David
- Bicknell Kelly
- Binns Debbie
- Birchley Alec
- Bird Paul W
- Bishop Chloe
- Blacow Rachel
- Blakey Victoria
- Blane Beth
- Bolt Frances
- Bonfield James
- Bonner Stephen
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Boyd Olivia
- Bradley Declan T
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgett Stephen
- Bronner Iraad F
- Brooks Ellena
- Broos Alice
- Brown Julianne R
- Bucca Giselda
- Buchan Sarah L
- Buck David
- Bull Matthew
- Burns Phillipa J
- Burton-Fanning Shirelle
- Byaruhanga Timothy
- Byott Matthew
- Campbell Sharon
- Carabelli Alessandro M
- Cargill James S
- Carlile Matthew
- Carmichael Stephen
- Carvalho SÃlvia F
- Casey Anna
- Castigador Anibolina
- Catalan Jana
- Chalker Vicki
- Chaloner Nicola J
- Chand Mrera
- Chapman Michael H Spencer
- Chappell Joseph G
- Charalampous Themoula
- Chatterton Wendy
- Chaudhry Yasmin
- Christofidis Nicolaos
- Churcher Carol M
- Clark Gemma
- Clarke Phillip
- Cogger Benjamin J
- Cole Kevin
- Collins Jennifer
- Colquhoun Rachel
- Connor Thomas R
- Cook Kate F
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nicholas
- Cotic Marius
- Cotton Seb
- Cottrell Simon
- Coupland Lindsay
- Cox Alison
- Cox MacGregor
- Craine Noel
- Crawford Liam
- Cross Aidan
- Crown Matthew R
- Crudgington Dorian
- Cumley Nicola
- Curran Martin D
- Curran Tanya
- da Silva Filipe Ana
- da Silva Filipe Ana
- Dabrera Gavin
- Darby Alistair C
- Davidson Rose K
- Davies Alisha
- Davies Robert M
- Davis Thomas
- de Angelis Daniela
- De Lacy Elen
- de Oliveira Martins Leonardo
- de Silva Thushan I
- Debebe Johnny
- Denton-Smith Rebecca
- Dervisevic Samir
- Dewar Rebecca
- Dey Jayasree
- Dias Joana
- Dobie Donald
- Dorman Matthew J
- Downing Fatima
- Driscoll Megan
- du Plessis Louis
- Duckworth Nichola
- Durham Jillian
- Eastick Kirstine
- Easton Lisa J
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- El Bouzidi Kate
- Eldirdiri Sahar
- Ellaby Nicholas
- Elliott Scott
- Eltringham Gary
- Enright Jessica
- Ensell Leah
- Erkiert Michelle J
- Essex Sarah
- Evans Cariad
- Evans Johnathan M
- Everson William
- Fairley Derek J
- Fallon Karlie
- Fanaie Arezou
- Farr Ben W
- Fearn Christopher
- Feltwell Theresa
- Ferguson Lynne
- Fina Laia
- Flaviani Flavia
- Fleming Vicki M
- Forrest Sally
- Foster-Nyarko Ebenezer
- Foulkes Benjamin H
- Foulser Luke
- Fragakis Mireille
- Frampton Dan
- Francois Sarah
- Fraser Christophe
- Freeman Timothy M
- Fryer Helen
- Fuchs Marc
- Fuller William
- Gajee Kavitha
- Galai Katerina
- Gallagher Abbie
- Gallagher Eileen
- Gallagher Michael D
- Gallis Marta
- Gaskin Amy
- Gatica-Wilcox Bree
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P
- Gifford Laura
- Gilbert Lauren
- Girgis Sophia T
- Glaysher Sharon
- Goldstein Emily J
- Goldstein Emily J
- Golubchik Tanya
- Gomes Andrea N
- Gonçalves Sónia
- Goodfellow Ian G
- Goodwin Scott
- Goudarzi Salman
- Gourtovaia Marina
- Graham Clive
- Graham Lee
- Grant Paul R
- Green Angie
- Green Luke R
- Greenaway Jane
- Gregory Richard
- Griffiths Emily
- Guest Martyn
- Gunson Rory N
- Gunson Rory N
- Gupta Ravi K
- Gutierrez Bernardo
- Haldenby Sam T
- Hamilton William L
- Hansford Samantha E
- Haque Tanzina
- Harris Kathryn A
- Harrison Ewan M
- Harrison Ian
- Hart Jennifer
- Harvey Matthew
- Harvey William T
- Hassan-Ibrahim Mohammed O
- Heaney Judith
- Helmer Thomas
- Henderson John H
- Hesketh Andrew R
- Hey Jessica
- Heyburn David
- Higginson Ellen E
- Hill Jack D
- Hill Verity
- Hilson Rachel A
- Hilvers Ember
- Holden Matthew TG
- Holden Matthew TG
- Hollis Amy
- Holmes Alison H
- Holmes Christopher W
- Holmes Nadine
- Hopes Richard
- Hornsby Hailey R
- Hosmillo Myra
- Houlihan Catherine
- Howson-Wells Hannah C
- Hsu Sharon N
- Hubb Jonathan
- Huckson Hannah
- Hughes Joseph
- Hughes Joseph
- Hughes Margaret
- Hughes Warwick
- Hutchings Stephanie
- Idle Giles
- Illingworth Chris J
- Illingworth Christopher JR
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Izuagbe Rhys
- Jackson Ben
- Jackson Chris
- Jackson David K
- Jackson Kathryn A
- Jackson Leigh M
- Jahun Aminu S
- James Keith
- James Victoria
- Jeanes Christopher
- Jeffries Aaron R
- Jeremiah Sarah
- Jermy Andrew
- John Michaela
- Johnson Kate
- Johnson Rob
- Johnston Ian
- Jones Christopher R
- Jones Hannah
- Jones Neil
- Jones Owen
- Jones Sophie
- Joseph Amelia
- Judges Sarah
- Kay Gemma L
- Kay Sally
- Keatley Jon-Paul
- Keeley Alexander J
- Kenyon Anita
- Kermack Leanne M
- Khakh Manjinder
- Kidd Stephen P
- Kimuli Maimuna
- Kirk Stuart
- Kitchen Christine
- Kitchman Katie
- Knight Bridget A
- Koshy Cherian
- Kraemer Moritz UG
- Kumziene-Summerhayes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Laing Kenneth G
- Lampejo Temi
- Langford Cordelia F
- Lavin Deborah
- Lawton Andrew I
- Le-Viet Thanh
- Lee David
- Lee Jack CD
- Lensing Stefanie V
- Leonard Steven
- Levett Lisa J
- Lewis Jonathan
- Lewis Kevin
- Liddle Jennifier
- Liggett Steven
- Lillie Patrick J
- Lindsey Benjamin B
- Lister Michelle M
- Livett Rich
- Lo Stephanie
- Loman Nicholas J
- Loose Matthew W
- Louka Stavroula F
- Loveson Katie F
- Lowdon Sarah
- Lowe Hannah
- Lowe Helen L
- Lucaci Anita O
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A
- Lythgoe Katrina
- Machin Nicholas W
- MacIntyre-Cockett George
- Mack Andrew
- Macklin Ben
- Maclean Alasdair
- Macnaughton Emily
- Madona Pinglawathee
- Maes Mailis
- Maftei Laurentiu
- Mahanama Adhyana IK
- Mahungu Tabitha W
- Mair Daniel
- Maksimovic Joshua
- Malone Cassandra S
- Maloney Daniel
- Manesis Nikos
- Manley Robin
- Mantzouratou Anna
- Marchbank Angela
- Mariappan Arun
- Martincorena Inigo
- Mather Alison E
- Maxwell Patrick
- Mayhew Megan
- Mbisa Tamyo
- McCann Clare M
- McCarthy Shane A
- McCluggage Kathryn
- McClure Patrick C
- McCrone JT
- McHugh Martin P
- McKenna James P
- McKerr Caoimhe
- McManus Georgina M
- McMurray Claire
- McMurray Claire L
- McNally Alan
- Meadows Lizzie
- Medd Nathan
- Megram Oliver
- Menegazzo Mirko
- Merrick Ian
- Michell Stephen L
- Michelsen Michelle L
- Milosevic Catriona
- Mirfenderesky Mariyam
- Mirza Jeremy
- Miskelly Julia
- Moles-Garcia Emma
- Moll Robin J
- Molnar Zoltan
- Monahan Irene M
- Mondani Matteo
- Mookerjee Siddharth
- Moore Catherine
- Moore Christopher
- Moore Jonathan
- Moore Nathan
- Morcrette Helen
- Morgan Mari
- Morgan Sian
- Mori Matilde
- Morriss Arthur
- Moses Samuel
- Mower Craig
- Muir Peter
- Mukaddas Afrida
- Munemo Florence
- Munn Robert
- Murray Abigail
- Murray Darren R
- Murray Leanne J
- Mutingwende Manasa
- Myers Richard
- Nastouli Eleni
- Nebbia Gaia
- Nelson Andrew
- Nelson Charlotte
- Nicholls Sam
- Nichols Jenna
- Nickbakhsh Sema
- Nicodemi Roberto
- Nomikou Kyriaki
- Nomikou Kyriaki
- Nunez Rocio T Martinez
- Odedra Mina
- Ohemeng-Kumi Natasha
- Oliver Karen
- Orton Richard
- Orton Richard J
- Osman Husam
- O’Brien Sarah
- O’Grady Justin
- O’Toole Áine
- Pacchiarini Nicole
- Padgett Debra
- Page Andrew J
- Palmalux Natasha
- Park Emily J
- Park Naomi R
- Parker Matthew D
- Parmar Surendra
- Partridge David G
- Pascall David
- Patel Amita
- Patel Bindi
- Paterson Steve
- Payne Brendan AI
- Peacock Sharon J
- Pearson Clare
- Pelosi Emanuela
- Percival Benita
- Perkins Jon
- Perry Malorie
- Pinckert Malte L
- Platt Steven
- Podplomyk Olga
- Pohare Manoj
- Pond Marcus
- Pope Cassie F
- Poplawski Radoslaw
- Powell Jessica
- Poyner Jennifer
- Prestwood Liam
- Price Anna
- Price James R
- Prieto Jacqui A
- Pritchard David T
- Prosolek Sophie J
- Pugh Georgia
- Pusok Monika
- Pybus Oliver G
- Pymont Hannah M
- Quail Michael A
- Quick Joshua
- Radulescu Clara
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajan Diana
- Rajatileka Shavanthi
- Ramadan Newara A
- Rambaut Andrew
- Ramble John
- Randell Paul
- Randell Paul A
- Ratcliffe Liz
- Raviprakash Veena
- Raza Mohammad
- Redshaw Nicholas M
- Rey Sara
- Reynolds Nicola
- Richter Alex
- Robertson David L
- Robertson David L
- Robinson Esther
- Robson Samuel C
- Rogan Fiona
- Rooke Stefan
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Rushton Steven
- Saeed Kordo
- Samaraweera Buddhini
- Sambles Christine M
- Sanderson Roy
- Sanderson Theo
- Sang Fei
- Sass Thea
- Scher Emily
- Scott Carol
- Scott Garren
- Sehmi Jasveen
- Shaaban Sharif
- Shaaban Sharif
- Shah Divya
- Shaw Jessica
- Shelest Ekaterina
- Shepherd James G
- Sheridan Liz A
- Sheriff Nicola
- Shirley Lesley
- Sillitoe John
- Silviera Siona
- Simpson David A
- Singh Aditi
- Singleton Dawn
- SkvortsovHartley Timofey John A
- Sloan Tim J
- Sluga Graciela
- Smith Colin P
- Smith Darren L
- Smith Ken
- Smith Kim S
- Smith Louise
- Smith Nikki
- Smith Perminder
- Smith-Palmer Alison
- Smollett Katherine
- Smollett Katherine L
- Snell Luke B
- Somassa Thomas
- Southgate Joel
- Spellman Karla
- Spurgin Lewis G
- Spyer Moira J
- Sreenu Vattipally B
- Stanley Rachael
- Stanley William
- Stanton Thomas D
- Starinskij Igor
- Stockton Joanne
- Stonehouse Susanne
- Storey Nathaniel
- Studholme David J
- Sudhanva Malur
- Swindells Emma
- Taha Yusri
- Tan Ngee Keong
- Tang Julian W
- Tang Miao
- Taylor Ben EW
- Taylor Joshua F
- Taylor Sarah
- Temperton Ben
- Templeton Kate
- Templeton Kate E
- Thomas Claire
- Thomson Emma
- Thomson Emma C
- Thomson Laura
- Thornton Alicia
- Thurston Scott AJ
- Todd John A
- Tomb Rachael
- Tomb Rachael M
- Tong Lily
- Tong Lily
- Tonkin-Hill Gerry
- Torok M Estee
- Tovar-Corona Jaime M
- Trebes Amy
- Trotter Alexander J
- Tsatsani Ioulia
- Turnbull Robyn
- Turtle Lance
- Twohig Katherine A
- Umpleby Helen
- Underwood Anthony P
- Vamos Edith E
- Vasylyeva Tetyana I
- Vattipally Sreenu
- Vernet Gabrielle
- Vipond Barry B
- Volz Erik M
- Walsh Sarah
- Wang Dennis
- Warne Ben
- Warwick-Dugdale Joanna
- Wastnedge Elizabeth
- Watkins Joanne
- Watson Louisa K
- Waugh Sheila
- Webster Hermione J
- Weldon Danni
- Westwick Elaine
- Whalley Thomas
- Wheeler Helen
- Whitehead Mark
- Whiteley Max
- Whitwham Andrew
- Wierzbicki Claudia
- Willford Nicholas J
- Williams Catryn
- Williams Charlotte A
- Williams Cheryl
- Williams Chris
- Williams Lesley-Anne
- Williams Rachel J
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A
- Wilson-Davies Eleri
- Witele Eric
- Withell Karen T
- Witney Adam A
- Wolverson Paige
- Wong Nick
- Workman Trudy
- Wright Derek W
- Wright Victoria
- Wyatt Tim
- Wyllie Sarah
- Xu-McCrae Li
- Yavus Mehmet
- Yaze Geraldine
- Yeats Corin A
- Yebra Gonzalo
- Yew Wen C
- Young Gregory R
- Young Jamie
- Zamudio Marina Escalera
- Zarebski Alex E
- Zhang Peijun
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 19/07/2022
- Field of study
AbstractWhole genome sequencing of SARS-CoV-2 has occurred at an unprecedented scale, and can be exploited for characterising outbreak risks at the fine-scale needed to inform control strategies. One setting at continued risk of COVID-19 outbreaks are higher education institutions, associated with student movements at the start of term, close living conditions within residential halls, and high social contact rates. Here we analysed SARS-CoV-2 whole genome sequences in combination with epidemiological data to investigate a large cluster of student cases associated with University of Glasgow accommodation in autumn 2020, Scotland. We identified 519 student cases of SARS-CoV-2 infection associated with this large cluster through contact tracing data, with 30% sequencing coverage for further analysis. We estimated at least 11 independent introductions of SARS-CoV-2 into the student population, with four comprising the majority of detected cases and consistent with separate outbreaks. These four outbreaks were curtailed within a week following implementation of control measures. The impact of student infections on the local community was short-term despite an underlying increase in community infections. Our study highlights the need for context-specific information in the formation of public health policy for higher educational settings.</jats:p
SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2
- Author
- Aanensen David M
- Abudahab Khalil
- Adams Alexander
- Adams Helen
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad SY
- Aigrain Louise
- Alcolea-Medina Adela
- Alikhan Nabil-Fareed
- Allara Elias
- Amato Roberto
- Angyal Adrienn
- Annett Tara
- Aplin Stephen
- Ariani Cristina V
- Asad Hibo
- Ash Amy
- Ashby Deborah
- Ashfield Paula
- Ashford Fiona
- Atchison Christina
- Atkinson Laura
- Attwood Stephen W
- Auckland Cressida
- Aydin Alp
- Baker David J
- Baker Paul
- Balcazar Carlos E
- Ball Jonathan
- Barclay Wendy
- Barrett Jeffrey C
- Barrow Magdalena
- Barton Edward
- Bashton Matthew
- Bassett Andrew R
- Batra Rahul
- Baxter Chris
- Bayzid Nadua
- Beaver Charlotte
- Beckett Angela H
- Beckwith Shaun M
- Bedford Luke
- Beer Robert
- Beggs Andrew
- Bellis Katherine L
- Berry Louise
- Bertolusso Beatrice
- Best Angus
- Betteridge Emma
- Bibby David
- Bicknell Kelly
- Binns Debbie
- Birchley Alec
- Bird Paul W
- Bishop Chloe
- Blacow Rachel
- Blakey Victoria
- Blane Beth
- Bodinier Barbara
- Bolt Frances
- Bonfield James
- Bonner Stephen
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Bouzidi Kate El
- Boyd Olivia
- Bradley Declan T
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgett Stephen
- Bronner Iraad F
- Brooks Ellena
- Broos Alice
- Brown Julianne R
- Bucca Giselda
- Buchan Sarah L
- Buck David
- Bull Matthew
- Burns Phillipa J
- Burton-Fanning Shirelle
- Byaruhanga Timothy
- Byott Matthew
- Campbell Sharon
- Carabelli Alessandro M
- Cargill James S
- Carlile Matthew
- Carvalho Sílvia F
- Casey Anna
- Castigador Anibolina
- Catalan Jana
- Chadeau-Hyam Marc
- Chalker Vicki
- Chaloner Nicola J
- Chand Meera
- Chapman Michael H Spencer
- Chappell Joseph G
- Charalampous Themoula
- Chatterton Wendy
- Chaudhry Yasmin
- Churcher Carol M
- Clark Gemma
- Clarke Phillip
- Cogger Benjamin J
- Cole Kevin
- Collins Jennifer
- Colquhoun Rachel
- Connor Thomas R
- Cook Kate F
- Cooke Graham
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nicholas
- Cotic Marius
- Cotton Seb
- Cottrell Simon
- Coupland Lindsay
- Cox Alison
- Cox MacGregor
- Craine Noel
- Crawford Liam
- Cross Aidan
- Crown Matthew R
- Crudgington Dorian
- Cumley Nicola
- Curran Martin D
- Curran Tanya
- da Silva Filipe Ana
- Dabrera Gavin
- Darby Alistair C
- Darzi Ara
- Davidson Rose K
- Davies Alisha
- Davies Robert M
- Davis Thomas
- de Angelis Daniela
- De Lacy Elen
- de Oliveira Martins Leonardo
- de Silva Thushan I
- Debebe Johnny
- Denton-Smith Rebecca
- Dervisevic Samir
- Dewar Rebecca
- Dey Jayasree
- Dias Joana
- Dobie Donald
- Donnelly Christl A
- Dorman Matthew J
- Downing Fatima
- Driscoll Megan
- du Plessis Louis
- Duckworth Nichola
- Durham Jillian
- Eales Oliver
- Eastick Kirstine
- Easton Lisa J
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- Eldirdiri Sahar
- Ellaby Nicholas
- Elliott Paul
- Elliott Scott
- Eltringham Gary
- Ensell Leah
- Erkiert Michelle J
- Essex Sarah
- Evans Cariad
- Evans Johnathan M
- Everson William
- Fairley Derek J
- Fallon Karlie
- Fanaie Arezou
- Farr Ben W
- Fearn Christopher
- Feltwell Theresa
- Ferguson Lynne
- Fina Laia
- Flaviani Flavia
- Fleming Vicki M
- Forrest Sally
- Foster-Nyarko Ebenezer
- Foulkes Benjamin H
- Foulser Luke
- Fragakis Mireille
- Frampton Dan
- Francois Sarah
- Fraser Christophe
- Freeman Timothy M
- Fryer Helen
- Fuchs Marc
- Fuller William
- Gajee Kavitha
- Galai Katerina
- Gallagher Abbie
- Gallagher Eileen
- Gallagher Michael D
- Gallis Marta
- Gaskin Amy
- Gatica-Wilcox Bree
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P
- Gifford Laura
- Gilbert Lauren
- Girgis Sophia T
- Glaysher Sharon
- Goldstein Emily J
- Golubchik Tanya
- Gomes Andrea N
- Gonçalves Sónia
- Goodfellow Ian G
- Goodwin Scott
- Goudarzi Salman
- Gourtovaia Marina
- Graham Clive
- Graham Lee
- Grant Paul R
- Green Angie
- Green Luke R
- Greenaway Jane
- Gregory Richard
- Guest Martyn
- Gunson Rory N
- Gupta Ravi K
- Gutierrez Bernardo
- Haldenby Sam T
- Hamilton William L
- Hansford Samantha E
- Haque Tanzina
- Harris Kathryn A
- Harrison Ewan M
- Harrison Ian
- Hart Jennifer
- Hartley John A
- Harvey Matthew
- Harvey William T
- Hassan-Ibrahim Mohammed O
- Haw David
- Heaney Judith
- Helmer Thomas
- Henderson John H
- Hesketh Andrew R
- Hey Jessica
- Heyburn David
- Higginson Ellen E
- Hill Jack D
- Hill Verity
- Hilson Rachel A
- Hilvers Ember
- Holden Matthew TG
- Hollis Amy
- Holmes Alison H
- Holmes Christopher W
- Holmes Nadine
- Hopes Richard
- Hornsby Hailey R
- Hosmillo Myra
- Houlihan Catherine
- Howson-Wells Hannah C
- Hsu Sharon N
- Hubb Jonathan
- Huckson Hannah
- Hughes Joseph
- Hughes Margaret
- Hughes Warwick
- Hutchings Stephanie
- Idle Giles
- Illingworth Chris J
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Izuagbe Rhys
- Jackson Ben
- Jackson Chris
- Jackson David K
- Jackson Kathryn A
- Jackson Leigh M
- Jahun Aminu S
- James Keith
- James Victoria
- Jeanes Christopher
- Jeffries Aaron R
- Jeremiah Sarah
- Jermy Andrew
- John Michaela
- Johnson Kate
- Johnson Rob
- Johnston Ian
- Jones Christopher R
- Jones Hannah
- Jones Neil
- Jones Owen
- Jones Sophie
- Jonnerby Jakob
- Joseph Amelia
- Judges Sarah
- Kay Gemma L
- Kay Sally
- Keatley Jon-Paul
- Keeley Alexander J
- Kenyon Anita
- Kermack Leanne M
- Khakh Manjinder
- Kidd Stephen P
- Kimuli Maimuna
- Kirk Stuart
- Kitchen Christine
- Kitchman Katie
- Knight Bridget A
- Koshy Cherian
- Kraemer Moritz UG
- Kumziene-Summerhayes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Laing Kenneth G
- Lampejo Temi
- Langford Cordelia F
- Lavin Deborah
- Lawton Andrew I
- Le-Viet Thanh
- Lee David
- Lee Jack CD
- Lensing Stefanie V
- Leonard Steven
- Levett Lisa J
- Lewis Jonathan
- Lewis Kevin
- Liddle Jennifier
- Liggett Steven
- Lillie Patrick J
- Lindsey Benjamin B
- Lister Michelle M
- Livett Rich
- Lo Stephanie
- Loman Nicholas J
- Loose Matthew W
- Louka Stavroula F
- Loveson Katie F
- Lowdon Sarah
- Lowe Hannah
- Lowe Helen L
- Lucaci Anita O
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A
- Lythgoe Katrina
- Machin Nicholas W
- MacIntyre-Cockett George
- Mack Andrew
- Macklin Ben
- Maclean Alasdair
- Macnaughton Emily
- Madona Pinglawathee
- Maes Mailis
- Maftei Laurentiu
- Mahanama Adhyana IK
- Mahungu Tabitha W
- Mair Daniel
- Maksimovic Joshua
- Malone Cassandra S
- Maloney Daniel
- Manesis Nikos
- Manley Robin
- Mantzouratou Anna
- Marchbank Angela
- Mariappan Arun
- Martincorena Inigo
- Mather Alison E
- Maxwell Patrick
- Mayhew Megan
- Mbisa Tamyo
- McCann Clare M
- McCarthy Shane A
- McCluggage Kathryn
- McClure Patrick C
- McCrone JT
- McHugh Martin P
- McKenna James P
- McKerr Caoimhe
- McManus Georgina M
- McMurray Claire
- McMurray Claire L
- McNally Alan
- Meadows Lizzie
- Medd Nathan
- Megram Oliver
- Menegazzo Mirko
- MEng Ben EW Taylor
- Merrick Ian
- Michell Stephen L
- Michelsen Michelle L
- Mirfenderesky Mariyam
- Mirza Jeremy
- Miskelly Julia
- Moles-Garcia Emma
- Moll Robin J
- Molnar Zoltan
- Monahan Irene M
- Mondani Matteo
- Mookerjee Siddharth
- Moore Catherine
- Moore Christopher
- Moore Jonathan
- Moore Nathan
- Morcrette Helen
- Morgan Mari
- Morgan Sian
- Mori Matilde
- Morriss Arthur
- Moses Samuel
- Mower Craig
- Muir Peter
- Mukaddas Afrida
- Munemo Florence
- Munn Robert
- Murray Abigail
- Murray Darren R
- Murray Leanne J
- Mutingwende Manasa
- Myers Richard
- Nastouli Eleni
- Nebbia Gaia
- Nelson Andrew
- Nelson Charlotte
- Nicholls Sam
- Nichols Jenna
- Nicodemi Roberto
- Nomikou Kyriaki
- Nunez Rocio T Martinez
- Odedra Mina
- Ohemeng-Kumi Natasha
- Oliver Karen
- Orton Richard J
- Osman Husam
- O’Brien Prof Sarah
- O’Grady Justin
- O’Toole Áine
- Pacchiarini Nicole
- Padgett Debra
- Page Andrew J
- Park Emily J
- Park Naomi R
- Parker Matthew D
- Parmar Surendra
- Partridge David G
- Pascall David
- Patel Amita
- Patel Bindi
- Paterson Steve
- Payne Brendan AI
- Peacock Sharon J
- Pearson Clare
- Pelosi Emanuela
- Percival Benita
- Perkins Jon
- Perry Malorie
- Pinckert Malte L
- Platt Steven
- Podplomyk Olga
- Pohare Manoj
- Pond Marcus
- Pope Cassie F
- Poplawski Radoslaw
- Powell Jessica
- Poyner Jennifer
- Prestwood Liam
- Price Anna
- Price James R
- Prieto Jacqui A
- Pritchard David T
- Prosolek Sophie J
- Pugh Georgia
- Pusok Monika
- Pybus Oliver G
- Pymont Hannah M
- Quail Michael A
- Quick Joshua
- Radulescu Clara
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajan Diana
- Rajatileka Shavanthi
- Ramadan Newara A
- Rambaut Andrew
- Ramble John
- Randell Paul
- Randell Paul A
- Ratcliffe Liz
- Raviprakash Veena
- Raza Mohammad
- Redshaw Nicholas M
- Rey Sara
- Reynolds Nicola
- Richter Alex
- Riley Steven
- Robertson David L
- Robinson Esther
- Robson Samuel C
- Rogan Fiona
- Rooke Stefan
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Rushton Steven
- Saeed Kordo
- Samaraweera Buddhini
- Sambles Christine M
- Sanderson Roy
- Sanderson Theo
- Sang Fei
- Sass Thea
- Scher Emily
- Scott Carol
- Scott Garren
- Sehmi Jasveen
- Shaaban Sharif
- Shah Divya
- Shaw Jessica
- Shelest Ekaterina
- Shepherd James G
- Sheridan Liz A
- Sheriff Nicola
- Shirley Lesley
- Sillitoe John
- Silviera Siona
- Simpson David A
- Singh Aditi
- Singleton Dawn
- Skvortsov Timofey
- Sloan Tim J
- Sluga Graciela
- Smith Colin P
- Smith Darren L
- Smith Ken
- Smith Kim S
- Smith Louise
- Smith Nikki
- Smith Perminder
- Smollett Katherine L
- Snell Luke B
- Somassa Thomas
- Southgate Joel
- Spellman Karla
- Spurgin Lewis G
- Spyer Moira J
- Stanley Rachael
- Stanley William
- Stanton Thomas D
- Starinskij Igor
- Stockton Joanne
- Stonehouse Susanne
- Storey Nathaniel
- Studholme David J
- Sudhanva Malur
- Swindells Emma
- Taha Yusri
- Tan Ngee Keong
- Tang Julian W
- Tang Miao
- Taylor Graham
- Taylor Joshua F
- Taylor Sarah
- Temperton Ben
- Templeton Kate E
- Thomas Claire
- Thomson Emma C
- Thomson Laura
- Thornton Alicia
- Thurston Scott AJ
- Todd John A
- Tomb Rachael
- Tong Lily
- Tonkin-Hill Gerry
- Torok M Estee
- Tovar-Corona Jaime M
- Trebes Amy
- Trotter Alexander J
- Tsatsani Ioulia
- Turnbull Robyn
- Turtle Lance
- Twohig Katherine A
- Umpleby Helen
- Underwood Anthony P
- Vamos Edith E
- Vasylyeva Tetyana I
- Vattipally Sreenu
- Vernet Gabrielle
- Vipond Barry B
- Volz Erik M
- Walsh Sarah
- Wang Dennis
- Wang Haowei
- Ward Helen
- Warne Ben
- Warwick-Dugdale Joanna
- Wastnedge Elizabeth
- Watkins Joanne
- Watson Louisa K
- Waugh Sheila
- Webster Hermione J
- Weldon Danni
- Westwick Elaine
- Whalley Thomas
- Wheeler Helen
- Whitehead Mark
- Whiteley Max
- Whitwham Andrew
- Wierzbicki Claudia
- Willford Nicholas J
- Williams Catryn
- Williams Charlotte A
- Williams Cheryl
- Williams Chris
- Williams Lesley-Anne
- Williams Rachel J
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A
- Wilson-Davies Eleri
- Witele Eric
- Withell Karen T
- Witney Adam A
- Wolverson Paige
- Wong Nick
- Workman Trudy
- Wright Derek W
- Wright Victoria
- Wyatt Tim
- Wyllie Sarah
- Xu-McCrae Li
- Yavus Mehmet
- Yaze Geraldine
- Yeats Corin A
- Yebra Gonzalo
- Yew Wen C
- Young Gregory R
- Young Jamie
- Zamudio Marina Escalera
- Zarebski Alex E
- Zhang Peijun
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 27/07/2022
- Field of study
Abstract Background Since the emergence of SARS-CoV-2, evolutionary pressure has driven large increases in the transmissibility of the virus. However, with increasing levels of immunity through vaccination and natural infection the evolutionary pressure will switch towards immune escape. Genomic surveillance in regions of high immunity is crucial in detecting emerging variants that can more successfully navigate the immune landscape. Methods We present phylogenetic relationships and lineage dynamics within England (a country with high levels of immunity), as inferred from a random community sample of individuals who provided a self-administered throat and nose swab for rt-PCR testing as part of the REal-time Assessment of Community Transmission-1 (REACT-1) study. During round 14 (9 September–27 September 2021) and 15 (19 October–5 November 2021) lineages were determined for 1322 positive individuals, with 27.1% of those which reported their symptom status reporting no symptoms in the previous month. Results We identified 44 unique lineages, all of which were Delta or Delta sub-lineages, and found a reduction in their mutation rate over the study period. The proportion of the Delta sub-lineage AY.4.2 was increasing, with a reproduction number 15% (95% CI 8–23%) greater than the most prevalent lineage, AY.4. Further, AY.4.2 was less associated with the most predictive COVID-19 symptoms (p = 0.029) and had a reduced mutation rate (p = 0.050). Both AY.4.2 and AY.4 were found to be geographically clustered in September but this was no longer the case by late October/early November, with only the lineage AY.6 exhibiting clustering towards the South of England. Conclusions As SARS-CoV-2 moves towards endemicity and new variants emerge, genomic data obtained from random community samples can augment routine surveillance data without the potential biases introduced due to higher sampling rates of symptomatic individuals. </jats:sec
Genomic reconstruction of the SARS-CoV-2 epidemic in England
- Author
- Aanensen David M
- Abnizova Irina
- Abudahab Khalil
- Adams Alexander
- Adams Helen
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad SY
- Aigrain Louise
- Alcolea Adela
- Alderton Alex
- Ali Mozam
- Alikhan Nabil-Fareed
- Allara Elias
- Allen Laura
- Amato Roberto
- Anderson Ralph
- Angyal Adrienn
- Annett Tara
- Aplin Stephen
- Ariani Cristina
- Ariani Cristina V
- Asad Hibo
- Ash Amy
- Ashfield Paula
- Ashford Fiona
- Atkinson Laura
- Attwood Stephen W
- Auckland Cressida
- Austin-Guest Siobhan
- Aydin Alp
- Baker David J
- Baker Paul
- Bala Sendu
- Balcazar Carlos E
- Ball Jonathan
- Barrett Jeffrey
- Barrett Jeffrey C
- Barrow Magdalena
- Barton Edward
- Bashton Matthew
- Bassett Andrew
- Bassett Andrew R
- Batra Rahul
- Battleday Kristina
- Baxter Chris
- Bayzid Nadua
- Beal James
- Beale Mathew
- Beaver Charlotte
- Beckett Angela H
- Beckwith Shaun M
- Bedford Luke
- Beer Robert
- Beggs Andrew
- Bellany Sam
- Bellerby Tristram
- Bellis Katherine L
- Bellis Katie
- Berger Duncan
- Berriman Matt
- Berry Louise
- Bertolusso Beatrice
- Best Angus
- Betteridge Emma
- Bevan Paul
- Bibby David
- Bicknell Kelly
- Binley Simon
- Binns Debbie
- Birchley Alec
- Bird Paul W
- Birney Ewan
- Bishop Chloe
- Bishop Jason
- Blackburn Kirsty
- Blacow Rachel
- Blakey Victoria
- Blane Beth
- Bolt Frances
- Bonfield James
- Bonner Stephen
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Boughton Nick
- Bourgeois Yann
- Bowker Sam
- Boyd Olivia
- Bradley Declan T
- Breen Cassie
- Brendler-Spaeth Timothy
- Bresner Catherine
- Breuer Judith
- Bridgett Stephen
- Bronner Iraad
- Bronner Iraad F
- Brooklyn Tanya
- Brooks Ellena
- Broos Alice
- Brown Julianne R
- Bucca Giselda
- Buchan Sarah L
- Buck David
- Buddenborg Sarah Kay
- Bull Matthew
- Burns Phillipa J
- Burton-Fanning Shirelle
- Bush Robert
- Byaruhanga Timothy
- Byott Matthew
- Caetano Catarina
- Cagan Alex
- Campbell Sharon
- Carabelli Alessandro M
- Cargill James S
- Carlile Matthew
- Carter Nicola
- Cartwright Joanna
- Carvalho Sílvia F
- Casey Anna
- Castigador Anibolina
- Catalan Jana
- Chalker Vicki
- Chaloner Nicola J
- Chand Meera
- Chand Meera
- Chapman Liz
- Chappell Joseph G
- Charalampous Themoula
- Chatterton Wendy
- Chaudhry Yasmin
- Chillingworth Tracey-Jane
- Churcher Carol M
- Clapham Peter
- Clark Gemma
- Clark Richard
- Clarke Adrian
- Clarke Catriona
- Clarke Phillip
- Cogger Benjamin J
- Cole Daryl
- Cole Kevin
- Collins Jennifer
- Colquhoun Rachel
- Connor Thomas R
- Cook Elizabeth
- Cook Kate F
- Coombes Jason
- Coppola Maria
- Corden Sally
- Cormie Claire
- Cornell Linda
- Cornwell Clare
- Cortes Nicholas
- Corton Craig
- Cotic Marius
- Cotton Seb
- Cottrell Simon
- Coupland Lindsay
- Cox Alison
- Cox MacGregor
- Crackett Abby
- Craine Noel
- Cranage Alison
- Craven Harriet
- Craw Sarah
- Crawford Liam
- Crawford Mark
- Cross Aidan
- Crown Matthew R
- Crudgington Dorian
- Cumley Nicola
- Curran Martin D
- Curran Tanya
- Cutts Tim
- da Silva Filipe Ana
- Dabrera Gavin
- Dabrowska Monika
- Darby Alistair C
- Davidson Rose K
- Davies Alisha
- Davies Matt
- Davies Robert
- Davies Robert M
- Davis Thomas
- Dawson Joseph
- Day Callum
- de Angelis Daniela
- De Lacy Elen
- De Maio Nicola
- de Oliveira Martins Leonardo
- de Silva Thushan I
- Debebe Johnny
- Densem Aiden
- Denton-Smith Rebecca
- Dervisevic Samir
- Dewar Rebecca
- Dey Jayasree
- Dias Joana
- Dibling Thomas
- Dobie Donald
- Dockree Cat
- Dodd David
- Dogga Sunil
- Dorman Matthew
- Dorman Matthew J
- Dougan Gordon
- Dougherty Martin
- Dove Alexander
- Downing Fatima
- Drummond Lucy
- Drury Eleanor
- du Plessis Louis
- Duckworth Nichola
- Dudek Monika
- Durham Jillian
- Durrant Laura
- Easthope Elizabeth
- Eastick Kirstine
- Easton Lisa J
- Eccles Richard
- Eckert Sabine
- Edgeworth Jonathan
- Edwards Sue
- El Bouzidi Kate
- Eldirdiri Sahar
- Ellaby Nicholas
- Elliott Scott
- Ellis Pete
- Eltringham Gary
- Ensell Leah
- Erkiert Michelle J
- Essex Sarah
- Evans Cariad
- Evans Johnathan M
- Everson William
- Fairley Derek J
- Fallon Karlie
- Fanaie Arezou
- Farr Ben
- Farr Ben W
- Fearn Christopher
- Feltwell Theresa
- Fenton Michael
- Ferguson Lynne
- Ferrero Marcella
- Fina Laia
- Flack Neil
- Flaviani Flavia
- Fleming Vicki M
- Fordham Howerd
- Forrest Sally
- Forsythe Grace
- Foster-Nyarko Ebenezer
- Foulkes Benjamin H
- Foulser Luke
- Fragakis Mireille
- Frampton Dan
- Francis Matt
- Francois Sarah
- Fraser Audrey
- Fraser Christophe
- Freeman Adam
- Freeman Timothy M
- Fryer Helen
- Fuchs Marc
- Fuller William
- Funk Sebastian
- Gajee Kavitha
- Galai Katerina
- Gallagher Abbie
- Gallagher Eileen
- Gallagher Michael D
- Gallis Marta
- Galvin Anastasia
- Garcia-Casado Maria
- Gaskin Amy
- Gatica-Wilcox Bree
- Gedny Alex
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P
- Gerstung Moritz
- Gifford Laura
- Gilbert Lauren
- Girgis Sophia
- Girgis Sophia T
- Glaysher Sharon
- Glover James
- Goater Richard
- Goldman Nick
- Goldstein Emily J
- Golubchik Tanya
- Gomes Andrea N
- Goncalves Sonia
- Gonçalves Sonia
- Gonçalves Sónia
- Goodfellow Ian G
- Goodwin Scott
- Goudarzi Salman
- Gould Oliver
- Gourtovaia Marina
- Graham Clive
- Graham Lee
- Grant Paul R
- Gray Andy
- Gray Emma
- Green Angie
- Green Luke R
- Greenaway Jane
- Gregory Richard
- Griffiths Coline
- Gu Yong
- Guerin Florence
- Guest Martyn
- Gunson Rory N
- Gupta Ravi K
- Gutierrez Bernardo
- Haldenby Sam T
- Hamilton Will
- Hamilton William L
- Hanks Hannah
- Hansford Samantha E
- Haque Tanzina
- Harris Kathryn A
- Harrison Ewan
- Harrison Ewan M
- Harrison Ian
- Harrott Alexandria
- Harry Edward
- Hart Jennifer
- Hartley John A
- Harvey Matthew
- Harvey William T
- Harvison Julia
- Hassan-Ibrahim Mohammed O
- Heaney Judith
- Heath Paul
- Hellewell Joel
- Helmer Thomas
- Henderson John H
- Hernandez-Koutoucheva Anastasia
- Hesketh Andrew R
- Hey Jessica
- Heyburn David
- Higginson Ellen E
- Hill Jack D
- Hill Verity
- Hilson Rachel A
- Hilvers Ember
- Hobbs Rhiannon
- Holden Matthew TG
- Holland Dave
- Hollis Amy
- Holmes Alison H
- Holmes Christopher W
- Holmes Nadine
- Holmes Sarah
- Hopes Richard
- Hornett Gary
- Hornsby Hailey R
- Hosmillo Myra
- Hough Nicholas
- Houlihan Catherine
- Howson-Wells Hannah C
- Hsu Sharon N
- Hubb Jonathan
- Huckle Liz
- Huckson Hannah
- Hughes Joseph
- Hughes Margaret
- Hughes Warwick
- Hughes-Hallet Lena
- Hunter Adam
- Hutchings Stephanie
- Idle Giles
- Illingworth Chris J
- Impey Robert
- Inglis Stephen
- Iqbal Sameena
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Izuagbe Rhys
- Jackson Adam
- Jackson Ben
- Jackson Chris
- Jackson David
- Jackson David K
- Jackson Kathryn A
- Jackson Leigh M
- Jahun Aminu S
- James Keith
- James Victoria
- Jamrozy Dorota
- Jeanes Christopher
- Jeffries Aaron R
- Jeremiah Sarah
- Jermy Andrew
- John Michaela
- Johnson Kate
- Johnson Rob
- Johnston Ian
- Jones Christopher R
- Jones Hannah
- Jones Matthew
- Jones Neil
- Jones Owen
- Jones Sophie
- Joseph Amelia
- Judges Sarah
- Jung Alexander W
- Kallepally Kalyan
- Kane Leanne
- Kay Gemma L
- Kay Keely
- Kay Sally
- Keatley Jon
- Keatley Jon-Paul
- Keeley Alexander J
- Keith Alan
- Kenyon Anita
- Kermack Leanne M
- Khakh Manjinder
- Kidd Stephen P
- Kimuli Maimuna
- King Alison
- Kirk Stuart
- Kitchen Christine
- Kitchin Lucy
- Kitchman Katie
- Kleanthous Matt
- Klimekova Martina
- Knight Bridget A
- Korlevic Petra
- Koshy Cherian
- Kraemer Moritz UG
- Krasheninnkova Ksenia
- Kumziene-Summerhayes Sara
- Kwiatkowski Dominic
- Kwiatkowski Dominic
- Lackenby Angie
- Laing Kenneth G
- Lampejo Temi
- Lane Greg
- Langford Cordelia
- Langford Cordelia F
- Laverack Adam
- Lavin Deborah
- Law Katharine
- Lawniczak Mara
- Lawton Andrew I
- Le-Viet Thanh
- Lee David
- Lee Jack CD
- Lensing Stefanie
- Lensing Stefanie V
- Leonard Steven
- Letchford Laura
- Levett Lisa J
- Lewis Jonathan
- Lewis Kevin
- Lewis-Wade Amanah
- Liddle Jennifer
- Liddle Jennifier
- Liggett Steven
- Lillie Patrick J
- Lin Quan
- Lindsay Sarah
- Lindsey Benjamin B
- Linsdell Sally
- Lister Michelle M
- Livett Rich
- Lo Stephanie
- Loman Nicholas J
- Long Rhona
- Loose Matthew W
- Louka Stavroula F
- Lovell Jamie
- Lovell Jon
- Loveson Katie F
- Lowdon Sarah
- Lowe Hannah
- Lowe Helen L
- Lucaci Anita O
- Ludden Catherine
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A
- Lythgoe Katrina
- Machin Nicholas W
- MacIntyre-Cockett George
- Mack Andrew
- Mack James
- Macklin Ben
- Maclean Alasdair
- Macnaughton Emily
- Maddison Mark
- Madona Pinglawathee
- Maes Mailis
- Maftei Laurentiu
- Mahanama Adhyana IK
- Mahungu Tabitha W
- Mair Daniel
- Maksimovic Joshua
- Makunin Aleksei
- Malone Cassandra S
- Maloney Daniel
- Mamun Irfan
- Manesis Nikos
- Manley Robin
- Mansfield Jenny
- Mantzouratou Anna
- Marchbank Angela
- Mariappan Arun
- Marriott Neil
- Martin Matt
- Martincorena Inigo
- Martinez Nunez Rocio T
- Masters Kathryn McCluggage
- Mather Alison E
- Maxwell Patrick
- Mayhew Megan
- Mayho Matthew
- Mbisa Tamyo
- McCann Clare M
- McCarthy Shane
- McCarthy Shane A
- McClintock Jo
- McClure Patrick C
- McCrone JT
- McGuigan Samantha
- McHugh Martin P
- McHugh Sandra
- McKenna James P
- McKerr Caoimhe
- McManus Georgina M
- McMinn Liz
- McMurray Claire
- McMurray Claire L
- McNally Alan
- Meadows Carl
- Meadows Lizzie
- Medd Nathan
- Megram Oliver
- Menegazzo Mirko
- Merrick Ian
- Michell Stephen L
- Michelsen Michelle L
- Mirfenderesky Mariyam
- Mirza Jeremy
- Miskelly Julia
- Mobley Emily
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- Weldon Danni
- Wells Alan
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- Westwick Elaine
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- Whalley Thomas
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- Whipp Theo
- Whitehead Mark
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- Whitton Georgia
- Whitwham Andrew
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- Wierzbicki Claudia
- Willford Nicholas J
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- Witele Eric
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- Wyllie Sarah
- Xu-McCrae Li
- Yavus Mehmet
- Yaze Geraldine
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- Yebra Gonzalo
- Yew Wen C
- Young Gregory R
- Young Jamie
- Zamudio Marina Escalera
- Zarebski Alex E
- Zhang Peijun
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 14/10/2021
- Field of study
AbstractThe evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus leads to new variants that warrant timely epidemiological characterization. Here we use the dense genomic surveillance data generated by the COVID-19 Genomics UK Consortium to reconstruct the dynamics of 71 different lineages in each of 315 English local authorities between September 2020 and June 2021. This analysis reveals a series of subepidemics that peaked in early autumn 2020, followed by a jump in transmissibility of the B.1.1.7/Alpha lineage. The Alpha variant grew when other lineages declined during the second national lockdown and regionally tiered restrictions between November and December 2020. A third more stringent national lockdown suppressed the Alpha variant and eliminated nearly all other lineages in early 2021. Yet a series of variants (most of which contained the spike E484K mutation) defied these trends and persisted at moderately increasing proportions. However, by accounting for sustained introductions, we found that the transmissibility of these variants is unlikely to have exceeded the transmissibility of the Alpha variant. Finally, B.1.617.2/Delta was repeatedly introduced in England and grew rapidly in early summer 2021, constituting approximately 98% of sampled SARS-CoV-2 genomes on 26 June 2021.</jats:p
Mapping the human genetic architecture of COVID-19
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- Abdullah T
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- zu Bentrup FM
- Zucchi P
- Zwinderman AHK
- Zyndorf M
- Publication venue
- Publication date
- 01/01/2021
- Field of study
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity. Here we describe the results of three genome-wide association meta-analyses that consist of up to 49,562 patients with COVID-19 from 46 studies across 19 countries. We report 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases3,4,5,6,7. They also represent potentially actionable mechanisms in response to infection. Mendelian randomization analyses support a causal role for smoking and body-mass index for severe COVID-19 although not for type II diabetes. The identification of novel host genetic factors associated with COVID-19 was made possible by the community of human genetics researchers coming together to prioritize the sharing of data, results, resources and analytical frameworks. This working model of international collaboration underscores what is possible for future genetic discoveries in emerging pandemics, or indeed for any complex human disease
A second update on mapping the human genetic architecture of COVID-19
- Author
- Abd Elghafar MS
- Abdel-Aziz M
- Abdelrazik M
- Abdullah MS
- Abe R
- Abe S
- Abel L
- Abel L
- Abernathy C
- Abraham R
- Abraheem A
- Abu Alragheb BO
- Abulail JA
- Acklery A
- Acosta-Herrera M
- Adachi T
- Adachi Y
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- Adanini O
- Afifi N
- Afilalo J
- Afilalo M
- Afolabi D
- Afrasiabi Z
- Afset JE
- Agasou A
- Aghemo A
- Agravante K
- Agrawal A
- Agrawal S
- Aguado JM
- Aguilar C
- Aguilar SEV
- Aguilar-Salinas CA
- Aguilera-Albesa S
- Agüero D
- Ahmad HF
- Ahmad N
- Ahmadhaider N
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- Ahmed C
- Ahram M
- Ai M
- Ain Q
- Aitkin E
- Akeroyd L
- Akhtar MN
- Akinkugbe O
- Al-Ani A
- Al-Ja’afreh MM
- Al-Kadash A
- Al-Kasasbeh MM
- Al-Moasseb H
- Al-Muftah W
- Al-Sarraj Y
- Alamer LM
- Alasdair F
- Alawneh FM
- Alawneh LM
- Albaiceta GM
- Albano G
- Albillos A
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- De Bustamante AD
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- De los Ángeles Vargas-Martínez M
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- Tuckey V
- Tuleutayev M
- Tully R
- Turebayeva G
- Turki S
- Turley C
- Turley P
- Turnbull A
- Turner L
- Turner P
- Turner V
- Turner-Bone I
- Turney S
- Turtle L
- Turvey SE
- Tusié-Luna T
- Tutt G
- Tutton R
- Twiss S
- Tyl D
- Tyler A
- Tzoulaki I
- Téllez L
- Uchimura Y
- Ueda S
- Ueda T
- Uellendahl-Werth F
- Uitterlinden AG
- Ullum H
- Umeda A
- Upadhyay KJ
- Upton J
- Urioste M
- Urrechaga E
- Usher M
- Utsugi M
- Uwamino Y
- Vadgama N
- Vadla MS
- Vaida M
- Valdeavella K
- Valdés PA
- Valencia-Ramos J
- Valenti L
- Valenzuela-Jorquera H
- Vallerga CL
- Valsecchi MG
- Van den Berge M
- Van der Laan S
- Van Heel DA
- Van Heel DA
- Van Koutrick L
- Vandernoot I
- Varghese M
- Vasilevska-Ristovska J
- Vassell K
- Vedage D
- Veerapen K
- Vega J
- Vehreschild MJGT
- Velasco DG
- Velázquez-Cruz R
- Venkatesh H
- Verdugo RA
- Verdugo RA
- Vergasova E
- Verlander M
- Vertue M
- Verula J
- Vigueras-Hernández A
- Vigurs C
- Villa A
- Villalonga JM
- Vincent R
- Virgilio E
- Virginia M-RA
- Vitart V
- Vizcaychipi M
- Vlasschaert C
- Vochin A
- Volland S
- Von Hohenstaufen Puoti KA
- Voza A
- Vuylsteke A
- Várnai R
- Vázquez-Pérez JA
- Wacker EM
- Wackett T
- Wadams B
- Waddell G
- Waddington N
- Wagner R
- Wagstaff V
- Waite AAC
- Wakabayashi A
- Wakahara K
- Wakefield P
- Wakinshaw F
- Waldron J
- Walker C
- Walker D
- Walker L
- Walker R
- Walker S
- Walker S
- Wall A
- Walsh T
- Walter J
- Walters RK
- Walton O
- Wang B
- Wang QS
- Wang X
- Wang X
- Ward D
- Ward G
- Ward K
- Ward L
- Ward M
- Ward S
- Warden S
- Warren D
- Warrington J
- Washington NL
- Wassall H
- Wasson C
- Watanabe H
- Watanabe K
- Waters A
- Waters E
- Watkins C
- Watson E
- Watson G
- Watson J
- Watters M
- Watts S
- Waugh V
- Weaver J
- Webb N
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- Webster D
- Webster K
- Wei S
- Wei Z
- Weiss ST
- Weldon CH
- Welford A
- Wells C
- Welters I
- Wendorff M
- Wendtner CM
- Werge T
- Wesse T
- West J
- Westergaard D
- Weston H
- Whileman A
- Whitaker E
- Whitbread J
- White D
- White I
- White K
- White M
- White N
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- Whitehead V
- Whitelaw L
- Whiteley S
- Whiteside J
- Whitney J
- Whitton C
- Whyte C
- Wicks SJ
- Wiegrebe S
- Wienbrandt L
- Wignall A
- Wilby L
- Wilcox L
- Wild H
- Wild L
- Wilding L
- Wiles M
- Wilfling S
- Wiliams A
- Wilkin F
- Wilkins J
- Wilkinson A
- Wilkinson B
- Williams A
- Williams A
- Williams C
- Williams D
- Williams E
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- Williams G
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- Williams M
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- Willis H
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- Willson J
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- Wilson DJ
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- Wilson JF
- Wiltfang J
- Winchester J
- Winkler TW
- Winmill H
- Winnard S
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- Winter K
- Winter-Goodwin B
- Wittig M
- Witzke O
- Wolf-Roberts R
- Wolford BN
- Wong I
- Wong J
- Wong J
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- Woodruff M
- Woods L
- Woodward E
- Woodward J
- Woolcock M
- Woolley AE
- Worner R
- Worsley L
- Wray G
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- Wreybrown C
- Wright C
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- Wright J
- Wright M
- Wright S
- Wrobel N
- Wu Y
- Wulandari R
- Wylie K
- Wyllie DH
- Wynter I
- Xavier K
- Xue X
- Yagi K
- Yamada M
- Yamada Y
- Yamagata K
- Yamasaki M
- Yang J
- Yaspan B
- Yassen AM
- Yasui Y
- Yates B
- Yatomi M
- Ye C
- Yermakovich D
- Yeung RSM
- Yi X
- Yonekawa A
- Yoo S
- Yoon K
- Yoshida K
- Yoshida S
- Yoshida S
- Yoshida T
- Yoshihara T
- Yoshiya K
- Yoshiyama T
- Young M
- Yue F
- Yun N
- Yáñez CE
- Yáñez Z
- Zainulabid UA
- Zainy T
- Zak A
- Zaki A
- Zamikula J
- Zamudio IPM
- Zanella A
- Zapata-Contreras D
- Zapatamartinez M
- Zarate R
- Zarei N
- Zavaleta DAF
- Zawadzki P
- Zawati MH
- Zborowski AC
- Zeberg H
- Zechner M
- Zhang Q
- Zhao X
- Zheng C
- Zheng T
- Zhlawi HJ
- Zhlawi MWJ
- Zholdybayeva E
- Zhou W
- Zhu W
- Zitter L
- Zoller H
- Zongo O
- Zorloni C
- Zuñiga-Pacheco P
- Zárate RN
- Zúñiga-Ramos J
- Álvarez BG
- Ávila-Arcos MA
- Ávila-Arcos MC
- Özer O
- Überla K
- Þorsteinsdóttir U
- Publication venue
- Nature Research
- Publication date
- 21/06/2023
- Field of study