5 research outputs found
Participatory Model Construction and Model Use in Natural Resource Management: a Framework for Reflection
- Author
- B Espinasse
- C Pahl-Wostl
- C Pahl-Wostl
- C. Els van Daalen
- CE Daalen van
- EJ Brown Gaddis
- F Bousquet
- F Maier
- G Rowe
- GP Richardson
- IS Mayer
- IS Mayer
- J Mingers
- J Rothenberg
- J Tippett
- L Hermans
- M Belt Van den
- M Kuit
- M Monticino
- M Shubik
- MA Janssen
- Pieter W. G. Bots
- PJ Beers
- PWG Bots
- RD Duke
- RG Dudley
- RO Mason
- S Lanini
- S Rist
- SR Arnstein
- TH Stevens
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Statistical Methods for Prehospital Care Research
- Author
- Afifi A A
- Brown C G
- Brown GW
- Craig D. Newgard
- Dawson-Saunders B
- Detsky A S
- Freiman J A
- Gaddis G M
- Gaddis G M
- Gaddis M L
- Gaddis ML
- Gallagher EJ
- Gausche M
- Goodman S N
- Lee K L
- Lee Y J
- Lewis R J
- Lewis R J
- Lewis RJ
- Lewis RJ
- Menegazzi J J
- Moher D
- O'Brien P C
- O'Brien P C
- O'Brien P C
- O'Brien P C
- O'Brien P C
- Oxman A D
- Roger J. Lewis
- Rothman K J
- Savitz D A
- Smith D G
- Young K D
- Young K D
- Yusuf S
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
TLR2 Directing PD-L2 Expression Inhibit T Cells Response in Schistosoma japonicum Infection
- Author
- A Iwasaki
- AH Sharpe
- D Onguru
- D van der Kleij
- DE Gaddis
- DG Colley
- DP McManus
- E Mendoza-Coronel
- E van Riet
- EJ Pearce
- EN Rozali
- F Goh
- F Wei
- G Grunig
- G Huang
- Geoffrey N. Gobert
- Guanling Wu
- Haiwei Wu
- J Correale
- JA Brown
- K Kiura
- L Oliveira-Nascimento
- LE Layland
- LI Terrazas
- Lin Chen
- M Chen
- M Collins
- M Moser
- M Zhang
- MB Drennan
- ME Keir
- Min Hou
- Minjun Ji
- N Watanabe
- O Takeuchi
- P Smith
- PA Saunders
- PG Thomas
- R Medzhitov
- RV Parry
- S Agrawal
- T Kawai
- T Pentcheva-Hoang
- Y Gao
- Y Kumagai
- Y Latchman
- Y Zhang
- Yanan Gao
- Yingying Chen
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Managing urban runoff in residential neighborhoods: Nitrogen and phosphorus in lawn irrigation driven runoff
- Author
- A Goonetilleke
- AK Bergström
- C Forsberg
- D Conley
- Darren Haver
- DB Lewis
- DE Line
- DJ Conley
- ED Stein
- EJ Brown Gaddis
- EM Bennett
- G Brion
- G Evanylo
- G Kim
- GA Graves
- Gurpal S. Toor
- HI Golterman
- HS Lim
- J García-Pintado
- J Ma
- J Vaze
- J Wu
- K Beckert
- K Gin
- K Johannesson
- K Song
- L Candela
- L Gray
- L Pfeifer
- LA Baker
- LHC Chua
- Lorence Oki
- LR Parsons
- M Badruzzaman
- M Lado
- M Obermann
- M Vadeboncoeur
- Marti L. Occhipinti
- MJ Paul
- MT Divers
- NP Miguntanna
- NP Miguntanna
- PM Groffman
- PM Nyenje
- R Manning
- R Uusitalo
- RJ Diaz
- S Yu
- SS Kaushal
- SS Kaushal
- SW Lee
- TA Endreny
- Tammy Majcherek
- TN McPherson
- VG Caccia
- W Rast
- WM Wollheim
- Yiu Fai Tsang
- Yun-Ya Yang
- YY Yang
- YY Yang
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Mapping the human genetic architecture of COVID-19
- Author
- Abdelrazik M
- Abdullah T
- Abe R
- Abe S
- Abecasis GR
- Abel L
- Abernathy C
- Abraheem A
- Abul-Husn NS
- Acosta-Herrera M
- Acquilini D
- Acquilini D
- Adachi T
- Adachi Y
- Adams C
- Adams K
- Adanini O
- Adeleye O
- Adeniji K
- Adra D
- Afifi N
- Afilalo J
- Afilalo M
- Afolabi D
- Afrasiabi Z
- Afset JE
- Agasou A
- Aghemo A
- Agranoff D
- Agrawal S
- Aguirre LA
- Agwuh K
- Ahmad HF
- Ahmad N
- Ahmed A
- Ahmed C
- Ahmed KA
- Ai M
- Ail D
- Akeroyd L
- Akhtar MN
- Akhtar S
- Akinkugbe O
- Aksentijevich A
- Al Thani A
- Al-Muftah W
- Al-Sarraj Y
- Alarcon C
- Alarcon-Riquelme ME
- Alasdair F
- Alaverdian D
- Alavere H
- Albertos R
- Albillos A
- Albrecht W
- Albrich W
- Albrich WC
- Aldera EL
- Aldridge J
- Alegria A
- Alex B
- Alexander P
- Alfonso J
- Algera AG
- Ali A
- Ali IMA
- Ali S
- Aliberti S
- Allan A
- Allan E
- Allan J
- Alldis Z
- Allen L
- Allen S
- Allibone S
- Allison KS
- Allos R
- Ally SM
- Almaden-Boyle C
- Altabaibeh A
- Altmueller J
- Alvaro A
- Amar D
- Amin V
- Amitrano S
- Amiya S
- Ampuero J
- Anan R
- Anania S
- Anastasescu E
- Anderson F
- Anderson J
- Anderson M
- Anderson P
- Anderson S
- Anderson S
- Anderson T
- Ando A
- Andolfo I
- Andrade V
- Andretta F
- Andreucci E
- Andreucci E
- Andrew A
- Andrew B
- Andrew G
- Andrews E
- Andrews SJ
- Andrews SJ
- Andrews SJ
- Andrews SJ
- Andrikopoulos P
- Anedda F
- Aneli S
- Anemoli V
- Angelini C
- Angus B
- Annis A
- Antcliffe D
- Antinori A
- Antoni MD
- Anumakonda V
- Anwar M
- Anzai T
- Apetri E
- Arai D
- Arana E
- Arbane G
- Archer K
- Arciero E
- Arden T
- Arias SS
- Arif S
- Arimura K
- Armstrong J
- Armstrong JA
- Armstrong L
- Armstrong R
- Arning N
- Arnold S
- Arora J
- Artuso R
- Arumugam P
- Asakura T
- Asano K
- Aschard H
- Ascolillo S
- Ashish A
- Ashley E
- Ashraf S
- Ashraf S
- Ashton L
- Ashworth M
- Asiimwe IG
- Aslibekyan S
- Asselta R
- Atanasovska B
- Atkinson D
- Atkinson EG
- Attwood B
- Aucella F
- Augustin M
- Auld D
- Auld F
- Austin K
- Austin P
- Auton A
- Auton A
- Avendano-Ortiz J
- Awano N
- Ayers A
- Azarzar S
- Aziz F
- Azuma M
- Azuure C
- Azzolini E
- Baba R
- Baba T
- Bach B
- Bacher P
- Bachetti T
- Badalamenti S
- Badia JR
- Badji RM
- Bahmer T
- Baikady RR
- Baillie JK
- Baillie JK
- Baillie JK
- Baillie JK
- Baines B
- Baines D
- Baines K
- Baird T
- Baird Y
- Bakshi S
- Bakthavatsalam D
- Balaconis MK
- Baldassarri M
- Baldini M
- Ball CA
- Bals R
- Baltzell AH
- Bamford A
- Bamford P
- Banach D
- Banagan J
- Banales JM
- Bancroft H
- Band G
- Bandera A
- Bandini M
- Bandla N
- Bano S
- Baptista D
- Barada O
- Baras A
- Baratti S
- Barber R
- Barbieri C
- Barbieri C
- Barbour A
- Barclay L
- Barclay WS
- Barda B
- Bargagli E
- Bari S
- Barker J
- Barlow G
- Barlow SL
- Barnass S
- Barnes KC
- Baroni S
- Baroni S
- Barreira A
- Barrett F
- Barrett KMS
- Barrett N
- Barron A
- Barry P
- Bartels M
- Bartley S
- Baruah R
- Baselli G
- Bashyal A
- Basikolo C
- Bassetti M
- Bassford C
- Basso MEF
- Bastion V
- Basude S
- Bates H
- Bates M
- Battle C
- Bauchmuller K
- Bax D
- Baxter D
- Baxter N
- Baya N
- Bayo L-A
- Beadle J
- Beadsworth M
- Beale R
- Bean S
- Beaumont K
- Beavis S
- Beck A
- Beckmann ND
- Beech E
- Beech V
- Beekes M
- Beesley K
- Begg C
- Beguin Y
- Behan T
- Beith CM
- Belagodu Z
- Belbin GM
- Belfield H
- Belhaj Y
- Beligni G
- Belisle A
- Bell D
- Bell G
- Bell M
- Bellamy M
- Belli MA
- Bellinghausen C
- Bellini A
- Bellwood R
- Below JE
- Bemand T
- Benetti E
- Benham L
- Bennet D
- Bennett S
- Bentley M
- Benyon S
- Beppu S
- Beranova E
- Bercades G
- Bergan J
- Bergantini L
- Berger MM
- Bergomi M
- Bergomi P
- Berkowitz N
- Bernardo D
- Bernasconi A
- Bernatoniene J
- Berridge J
- Bertrand A
- Best N
- Bettini LR
- Beudel M
- Bevan E
- Bewley J
- Bhardwaj N
- Bhatia N
- Bhatterjee R
- Bhuie P
- Bi R
- Bianchi F
- Bianco C
- Bibert S
- Bibert S
- Bibi F
- Biddle J
- Biesecker L
- Biggs H
- Biondi A
- Birch J
- Birch J
- Birch S
- Birchall K
- Birchall K
- Bird S
- Birkinshaw I
- Birney E
- Birt M
- Biscarini F
- Black E
- Black K
- Blackledge B
- Blackledge B
- Blackman H
- Blakemore H
- Blanco-Grau A
- Blasi F
- Blay N
- Blay N
- Blow S
- Blunt M
- Boada M
- Board S
- Bocciardi R
- Bocciolone M
- Bochud M
- Bochud P-Y
- Bochud PY
- Bochud PY
- Bochud PY
- Bociek A
- Boer C
- Boezen M
- Bogaard HJ
- Bogaert D
- Boillat N
- Boillat-Blanco N
- Bokhari M
- Bolton M
- Bolton R
- Bolze A
- Bombace S
- Bomers M
- Bonfanti P
- Bonner S
- Bonta PI
- Booker L
- Booth L
- Booth S
- Borislavova B
- Borra C
- Bos L
- Bosari S
- Bosio G
- Bosse Y
- Botello A
- Bothma P
- Botta G
- Botta M
- Boua PR
- Bouab M
- Bough L
- Boughton AP
- Boujemla B
- Bouras K
- Boutros P
- Bouysran Y
- Bowes A
- Bowles R
- Boyle P
- Boyle R
- Boz C
- Bradford Y
- Bradley C
- Bradley P
- Bradley-Potts J
- Bradshaw Z
- Brady A
- Brady M
- Brady R
- Brahier T
- Brandwood C
- Branney D
- Brantwood C
- Brassard N
- Braun A
- Braun N
- Brayne A
- Brealey D
- Brealey D
- Breen G
- Bremmer P
- Brennan B
- Brenner B
- Brenner T
- Bretherick AD
- Brett M
- Brett S
- Brickell K
- Bridgett V
- Brimfield L
- Brinkworth E
- Briton K
- Brittain-Long R
- Britvan B
- Bromley M
- Brooke H
- Brooks S
- Brouwer MC
- Brown A
- Brown A
- Brown A
- Brown CW
- Brown E
- Brown J
- Bruce M
- Brunak S
- Bruno R
- Brunton M
- Brusco A
- Bruttini M
- Bryant J
- Bryant S
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- Buckley C
- Buckley S
- Bugiani M
- Bujanda L
- Bulik CM
- Bulle E
- Bullock K
- Bulteel N
- Bunni L
- Burda D
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- Burn I
- Burnett C
- Burns K
- Burt K
- Burtenshaw A
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- Burton M
- Busani S
- Busson A
- Bussotti M
- Bustamante C
- Butcher D
- Buti M
- Butler A
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- Butler-Laporte G
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- Butte MJ
- Butterworth AS
- Butterworth-Cowin N
- Button H
- Buxbaum JD
- Buxbaum JD
- Buxbaum JD
- Byun J
- Caba Llero-Garralda A
- Cabrelli L
- Caceres M
- Cadilla CL
- Cagova L
- Caldarelli GP
- Calderon EJ
- Callaghan M
- Callier S
- Camby S
- Cameli P
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- Canaccini A
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- Carrabba M
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- Carreras Nolla A
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- Casey M
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- Castelli F
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- Castoldi M
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- Catlow L
- Catterall BWA
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- Chadwick D
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- Chapman S
- Charles B
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- Charney AW
- Charnock R
- Chasse M
- Chassot J
- Chaudhary K
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- Chechi K
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- Chen H-H
- Cheng N
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- Chernitsov A
- Cherubini A
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- Chittoor G
- Chiu A
- Cho JH
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- Choudhury Y
- Chowdhury M
- Christle J
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- Chueca N
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- Churchhouse C
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- Ciccarelli M
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- Cirulli ET
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- Cornely OA
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- White D
- White I
- White K
- White M
- White N
- White S
- Whitehouse T
- Whiteley S
- Whiteside J
- Whittaker P
- Whittington A
- Whittle H
- Whitton C
- Whyte C
- Wicks SJ
- Wienbrandt L
- Wiersinga WJ
- Wijesinghe M
- Wilby E
- Wilcock E
- Wilcox L
- Wilcox R
- Wild H
- Wild L
- Wild L
- Wilding L
- Wiles M
- Wilfling S
- Wilkin F
- Wilkins J
- Wilkinson A
- Wilkinson B
- Willer CJ
- Williams A
- Williams A
- Williams A
- Williams D
- Williams F
- Williams G
- Williams H
- Williams K
- Williams M
- Williams M
- Williams P
- Williams S
- Williams T
- Willis H
- Wills M
- Willson J
- Wilson A
- Wilson DJ
- Wilson J
- Wilson JF
- Wilson L
- Winchester S
- Winnard S
- Winter-Goodwin B
- Wiselka M
- Wittig M
- Witzke O
- Wolf-Roberts R
- Wolford B
- Wolford B
- Wolterman RA
- Wolverson A
- Wong J
- Wood D
- Wood H-L
- Wood S
- Wood T
- Woodford C
- Woodruff M
- Woods L
- Woodyatt W
- Woolley AE
- Wooton DG
- Working UCLAHATLASDM
- Workman A
- Worner R
- Worsley L
- Wouters D
- Wozniak H
- Wray G
- Wren L
- Wright D
- Wright J
- Wright J
- Wright M
- Wrobel N
- Wrobel N
- Wu Y
- Wulandari R
- Wyllie DH
- Wynter I
- Xavier K
- Xue X
- Yadav A
- Yagi K
- Yamada M
- Yamada Y
- Yamagata K
- Yamasaki M
- Yang G
- Yang J
- Yang Z
- Yaspan B
- Yasui Y
- Yates B
- Yates B
- Yatomi M
- Ye C
- Yengo L
- Yermakovich D
- Yi X
- Yonekawa A
- Yoon H
- Yoon KJ
- Yoshida K
- Yoshida S
- Yoshida S
- Yoshida T
- Yoshihara T
- Yoshiya K
- Yoshiyama T
- Youlton N
- Younes SE
- Young P
- Yun N
- Zak A
- Zaki A
- Zambon M
- Zamikula J
- Zanella A
- Zanella I
- Zanelli G
- Zara F
- Zara F
- Zarate R
- Zarate R
- Zborowski AC
- Zeberg H
- Zechner M
- Zechner M
- Zguro K
- Zhai R
- Zhang JE
- Zhang M
- Zhao JH
- Zhen J
- Zheng C
- Zheng T
- Zhou W
- Zhou W
- Zhu W
- Zitter L
- Zlatopolsky M
- Zoller H
- Zollner S
- Zongo O
- zu Bentrup FM
- Zucchi P
- Zwinderman AHK
- Zyndorf M
- Publication venue
- Publication date
- 01/01/2021
- Field of study
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity. Here we describe the results of three genome-wide association meta-analyses that consist of up to 49,562 patients with COVID-19 from 46 studies across 19 countries. We report 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases3,4,5,6,7. They also represent potentially actionable mechanisms in response to infection. Mendelian randomization analyses support a causal role for smoking and body-mass index for severe COVID-19 although not for type II diabetes. The identification of novel host genetic factors associated with COVID-19 was made possible by the community of human genetics researchers coming together to prioritize the sharing of data, results, resources and analytical frameworks. This working model of international collaboration underscores what is possible for future genetic discoveries in emerging pandemics, or indeed for any complex human disease