3,378 research outputs found

    Gestational surrogacy for women with recurrent pregnancy loss due to refractory chronic histiocytic intervillositis

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    Length- weight relationships, condition factor (K) and relative condition factor (Kn) of Sparids, Dentex congoensis (Maul, 1954) and Dentex angolensis (Maul and Poll, 1953), in Nigerian coastal water

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    Length-weight relationship and condition factors were estimated for Dentex congoensis and Dentex angolensis of the family sparidae trawled from Nigeria Coastal water in 2009. A total number of 534 specimens ranging from 7.2 – 3.0 cm in total length and 5.4 – 489.8 g in weight were analyzed. The lengthweight relationship is shown by the following equations: LogW –1.610 + 2.791logL (Dentex congoensis) and LogW = -1.558 + 2.776logL (D angolensis). The two species studied exhibited negative allometric growth (b < 3) with the mean b = 2.78 at p < 0.001. The correlation coefficient (R) values were 0.91 (Dentex congoensis) and 0.98 (D angolensis). The condition factor (K) and relative condition factor (Kn) were determined for each species separately. The condition factor (K) obtained for Dentex congoensis and Dentex angolensis were between 0.86 – 8.04 with mean value of 2.48 ± 0.58 and between 2.06 – 6.13 with mean value of 2.79 ± 0.42 respectively. The relative condition factor (Kn) values were 1.28 ±1.09 (Dentex congoensis) and 1.66 ± 2.44 (Dentex anoglensis). The maximum ‘Kn’ values were recorded during the length at first maturity and there was a general decreased in relative condition factor (Kn) with increase length for the two species

    Foot health education for people with rheumatoid arthritis : the practitioner's perspective

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    Background: Patient education is considered to be a key role for podiatrists in the management of patients with rheumatoid arthritis (RA). Patient education has undoubtedly led to improved clinical outcomes, however no attempts have been made to optimise its content or delivery to maximise benefits within the context of the foot affected by rheumatoid arthritis. The aim of this study was to identify the nature and content of podiatrists' foot health education for people with RA. Any potential barriers to its provision were also explored. Methods: A focus group was conducted. The audio dialogue was recorded digitally, transcribed verbatim and analysed using a structured, thematic approach. The full transcription was verified by the focus group as an accurate account of what was said. The thematic analysis framework was verified by members of the research team to ensure validity of the data. Results: Twelve members (all female) of the north west Podiatry Clinical Effectiveness Group for Rheumatology participated. Six overarching themes emerged: (i) the essence of patient education; (ii) the content; (iii) patient-centred approach to content and timing; (iv) barriers to provision; (v) the therapeutic relationship; and (vi) tools of the trade. Conclusion: The study identified aspects of patient education that this group of podiatrists consider most important in relation to its: content, timing, delivery and barriers to its provision. General disease and foot health information in relation to RA together with a potential prognosis for foot health, the role of the podiatrist in management of foot health, and appropriate self-management strategies were considered to be key aspects of content, delivered according to the needs of the individual. Barriers to foot health education provision, including financial constraints and difficulties in establishing effective therapeutic relationships, were viewed as factors that strongly influenced foot health education provision. These data will contribute to the development of a patient-centred, negotiated approach to the provision of foot health education for people with RA

    The Chronus Quantum software package

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    The Chronus Quantum (ChronusQ) software package is an open source (under the GNU General Public License v2) software infrastructure which targets the solution of challenging problems that arise in ab initio electronic structure theory. Special emphasis is placed on the consistent treatment of time dependence and spin in the electronic wave function, as well as the inclusion of relativistic effects in said treatments. In addition, ChronusQ provides support for the inclusion of uniform finite magnetic fields as external perturbations through the use of gauge-including atomic orbitals. ChronusQ is a parallel electronic structure code written in modern C++ which utilizes both message passing implementation and shared memory (OpenMP) parallelism. In addition to the examination of the current state of code base itself, a discussion regarding ongoing developments and developer contributions will also be provided. This article is categorized under: Software > Quantum Chemistry Electronic Structure Theory > Ab Initio Electronic Structure Methods Electronic Structure Theory > Density Functional Theory

    Leveraging icebreaking tasks to facilitate uptake of voice communication in multiplayer games

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    Voice Communication (VC) is widely employed by developers as an essential component of online games. Typically, it is assumed that communications through this mechanism will be helpful and enjoyable, but existing literature suggests that the entry into VC can be problematic. In this paper, we present a study that attempts to mitigate player discomfort when first engaging with VC with strangers, through the use of traditional icebreaking tasks. We integrate these into the game RET, an online cooperative first person shooter which requires effective communication for players to succeed. An online user study with 18 participants suggests that icebreaking tasks can contribute to a positive VC experience, but their inclusion also creates further issues to be considered for successful integration

    Increased Vascularity in Cervicovaginal Mucosa with Schistosoma haematobium Infection

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    Schistosomiasis is a fresh water parasite infection that affects millions of people, especially in Africa. Recent knowledge about the genital manifestations of schistosomiasis; especially its possible association with human immunodeficiency virus (HIV) infection, has led to increased focus on this neglected tropical disease. Millions of women remain undiagnosed for genital schistosomiasis, and may suffer from abnormal mucosal blood vessels, contact bleeding and lesions named sandy patches. This study analyses a unique selection of female genital biopsies containing parasite eggs. Protein detection and standard histopathological assessment are combined to quantify and study the characteristics of the mucosal blood vessels surrounding the eggs. Our results show that the genital mucosa with parasite eggs is more vascularised compared to healthy tissue, and that viable eggs tend to be surrounded by proliferating blood vessels. These findings have not yet been correlated directly to clinical manifestations. Further studies are needed in order to provide clinical advice on the risks and consequences of mucosal lesions particular to female genital schistosomiasis

    The ALMA Lupus protoplanetary disk survey: Evidence for compact gas disks and molecular rings from CN

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    The cyanide radical CN is abundant in protoplanetary disks, with line fluxes often comparable to those of 13CO. It is known to be sensitive to UV irradiation of the upper disk atmosphere, with models predicting ring-shaped emission. Aims. We seek to characterize the CN emission from 94 Class-II disks in the Lupus star-forming region, compare it to observations in other regions, and interpret our observations with a grid of models. The CN emission morphology is discussed for two primordial disks, Sz 71 and Sz 98, and is modeled in more detail. Methods. ALMA observed CN N = 32 in Lupus disks down to sensitivities better than previous surveys. Models constructed with the physico-chemical code DALI are used to study the integrated fluxes of the disks and resolved emission of CN in disks without (dust) substructures. Results. CN N = 32 is bright, and detected in 38% of sources, but its disk-integrated flux is not strongly correlated to either 13CO or continuum flux. Compared to pre-ALMA single-dish surveys, no significant difference in the CN flux distributions in Lupus and Taurus-Auriga is found, although Ophiuchus disks may be fainter on average. We find ring-shaped CN emission with peak radii of 50AU in two resolved disks. Conclusions. A large fraction of sources are faint in CN; only exponential gas surface density cutoffs at Rc 15AU can reconcile observations with models. This is the first observational evidence of such a compact gas disk population in Lupus. bsolute intensities and the emission morphology of CN are reproduced by DALI models without the need for any continuum substructure; they are unrelated to the CO snowline location. The observations presented here, together with the modeling of these rings, provide a new probe of the structure and conditions in disks, and particularly their incident UV radiation field, if disk size is determined from the data

    The ALMA Lupus protoplanetary disk survey: Evidence for compact gas disks and molecular rings from CN

    Get PDF
    The cyanide radical CN is abundant in protoplanetary disks, with line fluxes often comparable to those of 13CO. It is known to be sensitive to UV irradiation of the upper disk atmosphere, with models predicting ring-shaped emission. Aims. We seek to characterize the CN emission from 94 Class-II disks in the Lupus star-forming region, compare it to observations in other regions, and interpret our observations with a grid of models. The CN emission morphology is discussed for two primordial disks, Sz 71 and Sz 98, and is modeled in more detail. Methods. ALMA observed CN N = 32 in Lupus disks down to sensitivities better than previous surveys. Models constructed with the physico-chemical code DALI are used to study the integrated fluxes of the disks and resolved emission of CN in disks without (dust) substructures. Results. CN N = 32 is bright, and detected in 38% of sources, but its disk-integrated flux is not strongly correlated to either 13CO or continuum flux. Compared to pre-ALMA single-dish surveys, no significant difference in the CN flux distributions in Lupus and Taurus-Auriga is found, although Ophiuchus disks may be fainter on average. We find ring-shaped CN emission with peak radii of 50AU in two resolved disks. Conclusions. A large fraction of sources are faint in CN; only exponential gas surface density cutoffs at Rc 15AU can reconcile observations with models. This is the first observational evidence of such a compact gas disk population in Lupus. bsolute intensities and the emission morphology of CN are reproduced by DALI models without the need for any continuum substructure; they are unrelated to the CO snowline location. The observations presented here, together with the modeling of these rings, provide a new probe of the structure and conditions in disks, and particularly their incident UV radiation field, if disk size is determined from the data
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