328 research outputs found
The He(e, ed)p Reaction in q-constant Kinematics
The cross section for the He(e, ed)p reaction has been measured as a
function of the missing momentum in q -constant kinematics at
beam energies of 370 and 576 MeV for values of the three-momentum transfer
of 412, 504 and 604 \mevc. The L(+TT), T and LT structure functions have been
separated for = 412 and 504 \mevc. The data are compared to three-body
Faddeev calculations, including meson-exchange currents (MEC), and to
calculations based on a covariant diagrammatic expansion. The influence of
final-state interactions and meson-exchange currents is discussed. The
-dependence of the data is reasonably well described by all calculations.
However, the most advanced Faddeev calculations, which employ the AV18
nucleon-nucleon interaction and include MEC, overestimate the measured cross
sections, especially the longitudinal part, and at the larger values of .
The diagrammatic approach gives a fair description of the cross section, but
under(over)estimates the longitudinal (transverse) structure function.Comment: 17 pages, 7 figure
The He Cross Section at Large Missing Energy
The reaction on nuclei was studied in kinematics
designed to emphasize effects of nuclear short-range correlations. The measured
cross sections display a peak in the kinematical regions where two-nucleon
processes are expected to dominate. Theoretical models incorporating
short-range correlation effects agree reasonably with the data.Comment: 4 pages LaTeX, using espcrc1.sty and wrapfig.sty (included), two
figures. Talk presented by J. Templon at the 15th Int. Conf. on Few-Body
Problems in Physics, Groningen, The Netherlands, 22-26 July, 199
Evidence for Partial Occupancy of the 3s_1/2 Proton Orbital in 208-Pb
This research was sponsored by the National Science Foundation Grant NSF PHY 87-1440
Amyloid-driven disruption of default mode network connectivity in cognitively healthy individuals
Cortical accumulation of amyloid beta is one of the first events of Alzheimer's disease pathophysiology, and has been suggested to follow a consistent spatiotemporal ordering, starting in the posterior cingulate cortex, precuneus and medio-orbitofrontal cortex. These regions overlap with those of the default mode network, a brain network also involved in memory functions. Aberrant default mode network functional connectivity and higher network sparsity have been reported in prodromal and clinical Alzheimer's disease. We investigated the association between amyloid burden and default mode network connectivity in the preclinical stage of Alzheimer's disease and its association with longitudinal memory decline. We included 173 participants, in which amyloid burden was assessed both in CSF by the amyloid beta 42/40 ratio, capturing the soluble part of amyloid pathology, and in dynamic PET scans calculating the non-displaceable binding potential in early-stage regions. The default mode network was identified with resting-state functional MRI. Then, we calculated functional connectivity in the default mode network, derived from independent component analysis, and eigenvector centrality, a graph measure recursively defining important nodes on the base of their connection with other important nodes. Memory was tested at baseline, 2- and 4-year follow-up. We demonstrated that higher amyloid burden as measured by both CSF amyloid beta 42/40 ratio and non-displaceable binding potential in the posterior cingulate cortex was associated with lower functional connectivity in the default mode network. The association between amyloid burden (CSF and non-displaceable binding potential in the posterior cingulate cortex) and aberrant default mode network connectivity was confirmed at the voxel level with both functional connectivity and eigenvector centrality measures, and it was driven by voxel clusters localized in the precuneus, cingulate, angular and left middle temporal gyri. Moreover, we demonstrated that functional connectivity in the default mode network predicts longitudinal memory decline synergistically with regional amyloid burden, as measured by non-displaceable binding potential in the posterior cingulate cortex. Taken together, these results suggest that early amyloid beta deposition is associated with aberrant default mode network connectivity in cognitively healthy individuals and that default mode network connectivity markers can be used to identify subjects at risk of memory decline
Brain activation during cognitive planning in twins discordant or concordant for obsessive–compulsive symptoms
Neuroimaging studies have indicated abnormalities in cortico-striatal-thalamo-cortical circuits in patients with obsessive–compulsive disorder compared with controls. However, there are inconsistencies between studies regarding the exact set of brain structures involved and the direction of anatomical and functional changes. These inconsistencies may reflect the differential impact of environmental and genetic risk factors for obsessive–compulsive disorder on different parts of the brain. To distinguish between functional brain changes underlying environmentally and genetically mediated obsessive–compulsive disorder, we compared task performance and brain activation during a Tower of London planning paradigm in monozygotic twins discordant (n = 38) or concordant (n = 100) for obsessive–compulsive symptoms. Twins who score high on obsessive–compulsive symptoms can be considered at high risk for obsessive–compulsive disorder. We found that subjects at high risk for obsessive–compulsive disorder did not differ from the low-risk subjects behaviourally, but we obtained evidence that the high-risk subjects differed from the low-risk subjects in the patterns of brain activation accompanying task execution. These regions can be separated into those that were affected by mainly environmental risk (dorsolateral prefrontal cortex and lingual cortex), genetic risk (frontopolar cortex, inferior frontal cortex, globus pallidus and caudate nucleus) and regions affected by both environmental and genetic risk factors (cingulate cortex, premotor cortex and parts of the parietal cortex). Our results suggest that neurobiological changes related to obsessive–compulsive symptoms induced by environmental factors involve primarily the dorsolateral prefrontal cortex, whereas neurobiological changes induced by genetic factors involve orbitofrontal–basal ganglia structures. Regions showing similar changes in high-risk twins from discordant and concordant pairs may be part of compensatory networks that keep planning performance intact, in spite of cortico-striatal-thalamo-cortical deficits
Inclusive Electron Scattering from Nuclei at
The inclusive A(e,e') cross section for was measured on H,
C, Fe, and Au for momentum transfers from 1-7 (GeV/c). The scaling
behavior of the data was examined in the region of transition from y-scaling to
x-scaling. Throughout this transitional region, the data exhibit -scaling,
reminiscent of the Bloom-Gilman duality seen in free nucleon scattering.Comment: 4 pages, RevTeX; 4 figures (postscript in .tar.Z file
Tensor Analyzing Powers for Quasi-Elastic Electron Scattering from Deuterium
We report on a first measurement of tensor analyzing powers in quasi-elastic
electron-deuteron scattering at an average three-momentum transfer of 1.7
fm. Data sensitive to the spin-dependent nucleon density in the deuteron
were obtained for missing momenta up to 150 MeV/ with a tensor polarized
H target internal to an electron storage ring. The data are well described
by a calculation that includes the effects of final-state interaction,
meson-exchange and isobar currents, and leading-order relativistic
contributions.Comment: 4 pages, 3 figure
Spin-Momentum Correlations in Quasi-Elastic Electron Scattering from Deuterium
We report on a measurement of spin-momentum correlations in quasi-elastic
scattering of longitudinally polarized electrons with an energy of 720 MeV from
vector-polarized deuterium. The spin correlation parameter was
measured for the reaction for missing
momenta up to 350 MeV/ at a four-momentum transfer squared of 0.21
(GeV/c). The data give detailed information about the spin structure of the
deuteron, and are in good agreement with the predictions of microscopic
calculations based on realistic nucleon-nucleon potentials and including
various spin-dependent reaction mechanism effects. The experiment demonstrates
in a most direct manner the effects of the D-state in the deuteron ground-state
wave function and shows the importance of isobar configurations for this
reaction.Comment: 4 pages, 3 figures, submitted to Phys. Rev. Lett. for publicatio
Large ring polymers align FtsZ polymers for normal septum formation
The bacterial cell division protein FtsZ assembles into a circular structure at the site of cell division. SepF is important for cell division, but how it functions is not clear. Here, the findings show that SepF polymerizes into large rings that promote the assembly of FtsZ during septum formation
Proton G_E/G_M from beam-target asymmetry
The ratio of the proton's electric to magnetic form factor, G_E/G_M, can be
extracted in elastic electron-proton scattering by measuring either cross
sections, beam-target asymmetry or recoil polarization. Separate determinations
of G_E/G_M by cross sections and recoil polarization observables disagree for
Q^2 > 1 (GeV/c)^2. Measurement by a third technique might uncover an unknown
systematic error in either of the previous measurements. The beam-target
asymmetry has been measured for elastic electron-proton scattering at Q^2 =
1.51 (GeV/c)^2 for target spin orientation aligned perpendicular to the beam
momentum direction. This is the largest Q^2 at which G_E/G_M has been
determined by a beam-target asymmetry experiment. The result, \muG_E/G_M =
0.884 +/- 0.027 +/- 0.029, is compared to previous world data.Comment: 8 pages, 6 figures, Updated to be version published in Physical
Review
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