6 research outputs found
Radio-induced low-grade glioma: report of two cases and review of the literature
With the increasing number of cancer survivors,
we can observe a population that will present a higher
risk of developing secondary long-term toxicities related to
adjuvant chemo and radiotherapy regimens. Among these,
children surviving from acute lymphoblastic leukemia
(ALL) that were treated with prophylactic cranial irradiation
represent a group of patients at a high risk of
developing secondary brain tumors. Radiation-induced
intracranial tumors have been documented since 1950, and
today, more than one-hundred cases have been described.
We report our experience with two young patients who
were hospitalized for low grade gliomas and had a positive
anamnesis for ALL and consequent radiotherapy