Parameters affecting electrostatic cooling

A high voltage electrostatic field is discussed which enhances the rate of normal convective cooling. This cooling rate is a function of starting temperature and voltage applied, and an inverse function of atmospheric pressure or the heat capacity of the surrounding media. It appears that the cooling rate is also a function of current flow; however, additional work is needed to separate other variables from the effect of current flow. The maximum increase in heat loss over the normal convective cooling was approximately 0.167 C/sec (0.3 F/sec) at 316 C (600 F) and 20,000 V. From the data taken it is assumed that the addeded rate of cooling would be increased with higher temperatures and higher voltages. It appears that a high voltage field disrupts the molecular layer of air surrounding a hot body and increases the rate of convective cooling

North Korean Civil-Military Trends: Military-First Politics to a Point

Civil-military relations is one of the most challenging dimensions to deal with regarding North Korea. Since 1998, Pyongyang\u27s foremost policy has been declared as military-first. While experts debate the precise meaning and significance of this policy, considerable consensus exists that it gives the leading role to the Korean People\u27s Army (KPA. Hence, military leaders in the Democratic People\u27s Republic of Korea are very powerful and influential figures. Who are they? What kind of power and influence do these leaders wield, and how do they exert it? How do KPA leaders interact with dictator Kim Jong Il and their civilian counterparts? Mr. Ken Gause sets out to answer these questions in this monograph.https://press.armywarcollege.edu/monographs/1710/thumbnail.jp

Effects of nitrogen and potassium fertilization on the susceptibility of tomatoes to post-harvest proliferation of Salmonella enterica

Fresh fruits and vegetables are increasingly recognized as vehicles of salmonellosis. Pre- and post-harvest environmental conditions, and physiological, and genetic factors are thought to contribute to the ability of human pathogens to persist in the production environment, attach to, colonize and proliferate in and on raw produce. How field production conditions affect the post-harvest food safety outcomes is not entirely understood. This study tested how varying nitrogen and potassium fertilization levels affected the "susceptibility" of tomatoes to Salmonella infections following the harvest of fruits. Two tomato varieties grown over three seasons under high, medium, and low levels of nitrogen and potassium fertilization in two locations were inoculated with seven strains of Salmonella. Even though the main effects of nitrogen and potassium fertilization on the susceptibility of tomatoes to infections with Salmonella enterica were not statistically significant overall, differences in nitrogen concentrations in plant tissues correlated with the susceptibility of partially ripe tomatoes (cv. Solar Fire) to Salmonella. Tomato maturity and the season in which tomatoes were produced had the strongest effect on the ability of Salmonella to multiply in tomatoes. Tomato phenolics, accumulation of which is known to correlate with rates of the N fertilization, did not inhibit growth of Salmonella in vitro

Niche partitioning in a sympatric cryptic species complex

Competition theory states that multiple species should not be able to occupy the same niche indefinitely. Morphologically, similar species are expected to be ecologically alike and exhibit little niche differentiation, which makes it difficult to explain the co-occurrence of cryptic species. Here, we investigated interspeci- fic niche differentiation within a complex of cryptic bumblebee species that co-occur extensively in the United Kingdom. We compared the interspecific variation along different niche dimensions, to determine how they partition a niche to avoid competitive exclusion. We studied the species B. cryptarum, B. lucorum, and B. magnus at a single location in the northwest of Scotland throughout the flight season. Using mitochondrial DNA for species identifica- tion, we investigated differences in phenology, response to weather variables and forage use. We also estimated niche region and niche overlap between different castes of the three species. Our results show varying levels of niche partitioning between the bumblebee species along three niche dimensions. The species had contrasting phenologies: The phenology of B. magnus was delayed relative to the other two species, while B. cryptarum had a relatively extended phenology, with workers and males more common than B. lucorum early and late in the season. We found divergent thermal specialisation: In contrast to B. cryptarum and B. magnus, B. lucorum worker activity was skewed toward warmer, sunnier conditions, leading to interspecific temporal variation. Further- more, the three species differentially exploited the available forage plants: In particular, unlike the other two species, B. magnus fed predominantly on species of heather. The results suggest that ecological divergence in different niche dimensions and spatio-temporal heterogeneity in the environment may contribute to the persistence of cryptic species in sympatry. Furthermore, our study suggests that cryptic species provide distinct and unique ecosystem services, demonstrating that morphological similarity does not necessarily equate to ecological equivalence

Quantifying niche availability, niche overlap and competition for recruitment sites in plant populations without explicit knowledge of niche axes

1. Niche availability, niche overlap and competitive ability are key determinants of the distribution and abundance of species. However, quantifying each of these components is difficult because it is not always possible to identify or measure relevant environmental gradients (niche axes) along which species might partition or compete for niche space. 2. We describe a method that uses seed addition experiments to quantify the number of ‘safe-sites’ (microsites suitable for a species to recruit from seed) at a location and show how this method can be used to quantify niche availability, niche overlap and competitive ability. We illustrate our approach using two seed addition experiments in grassland. 3. In the first experiment, we added seeds of one native and two exotic grass species, alone and in mixture, to plots that were arrayed along a gradient of soil moisture availability. We show that the three species partitioned safe-sites, implying that all three species could locally co-occur through niche partitioning, in part due to different responses to moisture availability. 4. In the second experiment, we added seeds of three commonly co-occurring native grass species, alone and in mixture, to plots with no obvious environmental gradients. One species out-competed two others for site occupancy, allowing us to quantify both the degree of niche overlap and the relative ability of each species to compete for safe-site occupancy without a priori knowledge of the niche axes. Results from both experiments demonstrate the fine-scales at which species can partition niches to facilitate co-occurrence. 5. Synthesis. By conceptualising a plot of ground as containing a limited number of microsites that are safe for the recruitment of a given species, and using seed addition experiments to measure both the number of safe-sites and degree of safe-site overlap among species, we show how niche availability, niche overlap and competitive ability can be quantified at fine-scales without a priori knowledge of niche axes. Our approach allows questions about niche availability and competition for shared niche space to be empirically tested, and to examine how these processes vary along environmental gradients to shape species distributions and patterns of co‐occurrence

gas phase vibrational spectroscopy of V3O6-8+

We present gas phase vibrational spectra of the trinuclear vanadium oxide cations V3O6+·He1–4, V3O7+·Ar0,1, and V3O8+·Ar0,2 between 350 and 1200 cm−1. Cluster structures are assigned based on a comparison of the experimental and simulated IR spectra. The latter are derived from B3LYP/TZVP calculations on energetically low-lying isomers identified in a rigorous search of the respective configurational space, using higher level calculations when necessary. V3O7+ has a cage-like structure of C3v symmetry. Removal or addition of an O-atom results in a substantial increase in the number of energetically low-lying structural isomers. V3O8+ also exhibits the cage motif, but with an O2 unit replacing one of the vanadyl oxygen atoms. A chain isomer is found to be most stable for V3O6+. The binding of the rare gas atoms to V3O6–8+ clusters is found to be strong, up to 55 kJ/mol for Ar, and markedly isomer-dependent, resulting in two interesting effects. First, for V3O7+·Ar and V3O8+·Ar an energetic reordering of the isomers compared to the bare ion is observed, making the ring motif the most stable one. Second, different isomers bind different number of rare gas atoms. We demonstrate how both effects can be exploited to isolate and assign the contributions from multiple isomers to the vibrational spectrum. The present results exemplify the structural variability of vanadium oxide clusters, in particular, the sensitivity of their structure on small perturbations in their environment

Analytic Behaviour of Competition among Three Species

We analyse the classical model of competition between three species studied by May and Leonard ({\it SIAM J Appl Math} \textbf{29} (1975) 243-256) with the approaches of singularity analysis and symmetry analysis to identify values of the parameters for which the system is integrable. We observe some striking relations between critical values arising from the approach of dynamical systems and the singularity and symmetry analyses.Comment: 14 pages, to appear in Journal of Nonlinear Mathematical Physic

Fluctuation induces evolutionary branching in a modeled microbial ecosystem

The impact of environmental fluctuation on species diversity is studied with a model of the evolutionary ecology of microorganisms. We show that environmental fluctuation induces evolutionary branching and assures the consequential coexistence of multiple species. Pairwise invasibility analysis is applied to illustrate the speciation process. We also discuss how fluctuation affects species diversity.Comment: 4 pages, 4 figures. Submitted to Physical Review Letter

A pilot clinical trial testing mutant von Hippel-Lindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma

<p>Abstract</p> <p>Background</p> <p>Due to the lack of specific tumor antigens, the majority of tested cancer vaccines for renal cell carcinoma (RCC) are based on tumor cell lysate. The identification of the <it>von Hippel-Lindau </it>(<it>VHL</it>) gene mutations in RCC patients provided the potential for developing a novel targeted vaccine for RCC. In this pilot study, we tested the feasibility of vaccinating advanced RCC patients with the corresponding mutant VHL peptides.</p> <p>Methods</p> <p>Six patients with advanced RCC and mutated <it>VHL </it>genes were vaccinated with the relevant VHL peptides. Patients were injected with the peptide mixed with Montanide subcutaneously (SQ) every 4 weeks until disease progression or until the utilization of all available peptide stock.</p> <p>Results</p> <p>Four out of five evaluable patients (80%) generated specific immune responses against the corresponding mutant VHL peptides. The vaccine was well tolerated. No grade III or IV toxicities occurred. The median overall survival (OS) and median progression-free survival (PFS) were 30.5 and 6.5 months, respectively.</p> <p>Conclusions</p> <p>The vaccine demonstrated safety and proved efficacy in generating specific immune response to the mutant VHL peptide. Despite the fact that the preparation of these custom-made vaccines is time consuming, the utilization of VHL as a vaccine target presents a promising approach because of the lack of other specific targets for RCC. Accordingly, developing mutant VHL peptides as vaccines for RCC warrants further investigation in larger trials. Trial registration: 98C0139</p

Globally coupled chaotic maps and demographic stochasticity

The affect of demographic stochasticity of a system of globally coupled chaotic maps is considered. A two-step model is studied, where the intra-patch chaotic dynamics is followed by a migration step that coupled all patches; the equilibrium number of agents on each site, $N$, controls the strength of the discreteness-induced fluctuations. For small $N$ (large fluctuations) a period-doubling cascade appears as the coupling (migration) increases. As $N$ grows an extremely slow dynamic emerges, leading to a flow along a one-dimensional family of almost period 2 solutions. This manifold become a true solutions in the deterministic limit. The degeneracy between different attractors that characterizes the clustering phase of the deterministic system is thus the $N \to \infty$ limit of the slow dynamics manifold