A dynamic multi-attribute group emergency decision making method considering experts’ hesitation

Multi-attribute group emergency decision making (MAGEDM) has become a valuable research topic in the last few years due to its effectiveness and reliability in dealing with real-world emergency events (EEs). Dynamic evolution and uncertain information are remarkable features of EEs. The former means that information related to EEs is usually changing with time and the development of EEs. To make an effective and appropriate decision, such an important feature should be addressed during the emergency decision process; however, it has not yet been discussed in current MAGEDM problems. Uncertain information is a distinct feature of EEs, particularly in their early stage; hence, experts involved in aMAGEDM problem might hesitate when they provide their assessments on different alternatives concerning different criteria. Their hesitancy is a practical and inevitable issue, which plays an important role in dealing with EEs successfully, and should be also considered in real world MAGEDM problems. Nevertheless, it has been neglected in existing MAGEDM approaches. To manage such limitations, this study intends to propose a novel MAGEDM method that deals with not only the dynamic evolution of MAGEDM problems, but also takes into account uncertain information, including experts’ hesitation. A case study is provided and comparisons with current approaches and related discussions are presented to illustrate the feasibility and validity of the proposed method.This work was partly supported by the Young Doctoral Dissertation Project of Social Science Planning Project of Fujian Province (Project No. FJ2016C202), National Natural Science Foundation of China (Project No. 71371053, 61773123), Spanish National Research Project ( Project No. TIN2015-66524-P), and Spanish Ministry of Economy and Finance Postdoctoral Fellow (IJCI-2015- 23715)

Iron Metabolism in Obesity and Metabolic Syndrome

Obesity is an excessive adipose tissue accumulation that may have detrimental effects on health. Particularly, childhood obesity has become one of the main public health problems in the 21st century, since its prevalence has widely increased in recent years. Childhood obesity is intimately related to the development of several comorbidities such as nonalcoholic fatty liver disease, dyslipidemia, type 2 diabetes mellitus, non-congenital cardiovascular disease, chronic inflammation and anemia, among others. Within this tangled interplay between these comorbidities and associated pathological conditions, obesity has been closely linked to important perturbations in iron metabolism. Iron is the second most abundant metal on Earth, but its bioavailability is hampered by its ability to form highly insoluble oxides, with iron deficiency being the most common nutritional disorder. Although every living organism requires iron, it may also cause toxic oxygen damage by generating oxygen free radicals through the Fenton reaction. Thus, iron homeostasis and metabolism must be tightly regulated in humans at every level (i.e., absorption, storage, transport, recycling). Dysregulation of any step involved in iron metabolism may lead to iron deficiencies and, eventually, to the anemic state related to obesity. In this review article, we summarize the existent evidence on the role of the most recently described components of iron metabolism and their alterations in obesity

The distribution of mass components in simulated disc galaxies

Using 22 hydrodynamical simulated galaxies in a LCDM cosmological context we recover not only the observed baryonic Tully-Fisher relation, but also the observed "mass discrepancy--acceleration" relation, which reflects the distribution of the main components of the galaxies throughout their disks. This implies that the simulations, which span the range 52 < V$_{\rm flat}$ < 222 km/s where V$_{\rm flat}$ is the circular velocity at the flat part of the rotation curve, and match galaxy scaling relations, are able to recover the observed relations between the distributions of stars, gas and dark matter over the radial range for which we have observational rotation curve data. Furthermore, we explicitly match the observed baryonic to halo mass relation for the first time with simulated galaxies. We discuss our results in the context of the baryon cycle that is inherent in these simulations, and with regards to the effect of baryonic processes on the distribution of dark matter.Comment: 8 pages, 7 pdf figures. Accepted for publication in MNRAS on 2015 October 0

Managing Non-Homogeneous Information and Experts’ Psychological Behavior in Group Emergency Decision Making

After an emergency event (EE) happens, emergency decision making (EDM) is a common and effective way to deal with the emergency situation, which plays an important role in mitigating its level of harm. In the real world, it is a big challenge for an individual emergency manager (EM) to make a proper and comprehensive decision for coping with an EE. Consequently, many practical EDM problems drive group emergency decision making (GEDM) problems whose main limitations are related to the lack of flexibility in knowledge elicitation, disagreements in the group and the consideration of experts’ psychological behavior in the decision process. Hence, this paper proposes a novel GEDM approach that allows more flexibility for preference elicitation under uncertainty, provides a consensus process to avoid disagreements and considers experts’ psychological behavior by using the fuzzy TODIM method based on prospect theory. Eventually, a group decision support system (GDSS) is developed to support the whole GEDM process defined in the proposed method demonstrating its novelty, validity and feasibility.This work was partly supported by the Young Doctoral Dissertation Project of Social Science Planning Project of Fujian Province (Project No. FJ2016C202), National Natural Science Foundation of China (Project Nos. 71371053, 61773123), Spanish National Research Project (Project No. TIN2015-66524-P), and Spanish Ministry of Economy and Finance Postdoctoral Fellow (IJCI-2015-23715) and ERDF

Projection of diversity in Higher Education. A study of an institutional communication media in a Spanish university

(IndiquAtención a la diversidad y educación inclusiva en la universidad. Diagnóstico y evaluación de indicadores de institucionalización (I+D+i) (InclUni) (EDU2017-2862-R): http://www.uco.es/incluni/index.php/es/resultadose el organismo, el programa y el número de referencia del proyecto)The way in which diversity is conveyed through the media can reflect the attitude of the communicators themselves and contribute to shaping society’s attitudes towards diversity. The aim of the study was to identify how diversity is conveyed by the University to the Society. A content analysis of diversity-related news items in the University’s Institutional Newspaper Journal of the Pablo de Olavide University (DUPO) (626 news items out of 3,186 published between 2016 and 2019, a full rector’s term) was conducted. Heterogeneity in diversity was identified: gender, functional, cultural, sexual, religious and age, with gender and functional or disability diversity being predominant. Dissemination of diversity was linked to the fields of social sciences, humanities and sport. Communicators were government teams, with a slightly larger role for women. In conclusion, the institutional communication of diversity carried out from the most common official communication channel of the university analysed is the majority compared to the actions of professors and researchers, and a heterogeneous conception of diversity was found, linking it to issues of gender, inequalities and violence.Universidad Pablo de Olavide de Sevilla. Departamento de Educación y Psicología Socia

Tectonoelins, new norlignans from a bioactive extract of Tectona grandis

A phytochemical study on the most bioactive extract from Tectona grandis led to the isolation of two new norlignans, tectonoelin A and tectonoelin B, together with ten known compounds. The structures of the compounds were determined by a combination of 1D and 2D NMR techniques. This is the first time that this type of compound (C8–C80 linkage norlignans) has been isolated from a dicotyledon. The general bioactivities of the isolated compounds have been studied using etiolated wheat coleoptiles. The activities showed that the isolated lignans and norlignans should be part of the defence mechanisms of this plant

A CMOS 0.8 μm fully differential current mode buffer for HF SI circuits

El pdf del artículo es la versión post-print.We present a high-frequency fully-differential current-mode buffer to interface off-chip currents with no significant degradation of the frequency response, and to measure current-mode ICs using standard equipment. It has been fabricated in a 0.8μm double-poly double-metal CMOS technology and features more than 37MHz bandwidth. In order to show its functionality, this unit has been incorporated to the front end of a Switched-Current Band-Pass ΣΔ modulator featuring 9 bit dynamic range at 10MHz clock frequency for a 30kHz signal bandwidth centered at 2.5MHz.Peer reviewe

Restoring catalase activity in Staphylococcus aureus subsp. anaerobius leads to loss of pathogenicity for lambs

Staphylococcus aureus subsp. anaerobius, a microaerophilic and catalase-negative bacterium, is the etiological agent of abscess disease, a specific chronic condition of sheep and goats, which is characterized by formation of necrotic lesions that are located typically in superficial lymph nodes. We constructed an isogenic mutant of S. aureus subsp. anaerobius (RDKA84) that carried a repaired and functional catalase gene from S. aureus ATCC 12600, to investigate whether the lack of catalase in S. aureus subsp. anaerobius plays a role in its physiological and pathogenic characteristics. The catalase activity had no apparent influence on the in vitro growth characteristics of RDKA84, which, like the wild-type, did not grow on aerobically incubated agar plates. Restoration of catalase activity in RDKA84 substantially increased resistance to H2O2 when analyzed in a death assay. The intracellular survival rates of the catalase-positive mutant RDKA84 in polymorphonuclear neutrophils (PMN) isolated from adult sheep were significantly higher than those of the wild-type, while no differences were found with PMN isolated from lambs. RDKA84 showed significantly lower survival rates in murine macrophages (J774A.1 cells) than the wild-type strains did, whereas, in bovine mammary epithelial cells (MAC-T), no differences in intracellular survival were observed. Interestingly, the virulence for lambs, the natural host for abscess disease, of the catalase-positive mutant RDKA84 was reduced dramatically in comparison with wild-type S. aureus subsp. anaerobius in two experimental models of infection