Explanatory factors of university student participation in flamenco

The present work offers a study exploring University of Seville students’ cultural participation and how often they attend live flamenco shows. Based on the statistical yearbook of this university, a sample of 452 students from different fields was selected and, by applying a questionnaire, a binomial logit model and an ordered finance model were constructed. Our empirical findings offer descriptive, explanatory and predictive statistical results regarding participation and frequency. For example, the results evidence that 43% of the University of Seville students have never attended a live flamenco show and that one of the main issues influencing attendance is human and cultural capital

Economic and financial viability plan for the enterpreneurship of a lyric theatre low-cost company: The case of Zarzuela in Spain

Taking into account that one of the major handicaps when undertaken in the cultural sector is the problem of cost and demand volatility, this paper aims to implement a viability plan for the entrepreneurship of a lyric theatre low-cost company, dedicated to Zarzuela performance, a type of Spanish music like Opera. Firstly, the cultural sector data are analysed in terms of supply and demand and secondly a viability plan is carried out for three years. According to the results it is concluded that this type of venture is very risky if you do not have grant or other financial resources, due to the variability of demand and the increase in unit costs as the artistic performance has a fixed production technology that cannot absorb the technical progress of the rest of the economy

Perioperative management and early complications after intestinal resection with ileocolonic anastomosis in Crohn’s disease: analysis from the PRACTICROHN study

This study is aimed at describing the prevalence of and risk factors associated with early post-operative complications after Crohn’s disease-related intestinal resection. Methods: This was a retrospective analysis of data from the PRACTICROHN cohort. Adult Crohn’s disease patients who underwent ileocolonic resection with ileocolonic anastomosis between January 2007 and December 2010 were included. The complications evaluated included death, ileus, anastomotic leak, abscess, wound infection, catheter-related infection, digestive bleeding and other extra-abdominal infections that occurred in the 30 days after surgery.Results: A total of 364 patients (median age at surgery 38 years and 50% men) were included. Indication for surgery was: stricturing disease (46.4%), penetrating disease (31.3%), penetrating and stricturing disease (14.0%) or resistance to medical treatment (5.8%). Early complications were recorded in 100 (27.5%) patients, with wound infection, intra-abdominal abscess and anastomotic leakage being the most frequent complications. Median hospitalization duration was 16 days for patients with complications vs. 9 days without complications (P<0.001). Complications were more common among patients with penetrating disease (36/114, 31.6%) and those refractory to treatment (9/21, 42.9%) compared with stricturing disease (45/169, 26.6%) or stricturingþpenetrating disease (6/51, 11.8%) (P¼0.040). The rate of complications was higher among patients with diagnosis made at the time of surgery (15/31, 48.4%) compared with the rest (85/331, 25.7%) (P¼0.013). Medication received at the time of surgery did not affect the rate of complications. Conclusions: Almost a quarter of patients developed early complications after intestinal resection. Penetrating disease and urgent surgery were associated with an increased risk of complicationsThis study was supported by Merck Sharp and Dohme, Spai

Variabilidad de los conjuntos líticos en el Paleolítico Medio del Abric Romaní (Capellades, Barcelona)

El Abric Romaní cuenta con una potente secuencia del Paleolítico Medio de la que hasta el momento se han excavado 13 niveles arqueológicos. Estos niveles muestran un patrón de ocupación basado en la aparición de espacios domésticos en torno a hogares en los que se concentra la mayor parte de las actividades, especialmente las relacionadas con el procesamiento de los recursos líticos. Este patrón permite caracterizar el Abric Romaní como un espacio residencial, lo que es fundamental para entender el registro arqueológico y el comportamiento técnico. La variabilidad de los conjuntos líticos se ha abordado desde una triple perspectiva, relacionada con las diferentes escalas temporales a las que es posible acceder a través de la metodología arqueológica: la variabilidad que refleja procesos de larga duración y que se expresa en los cambios que se producen a lo largo de la secuencia; la variabilidad en el interior de conjunto lítico definido a partir de criterios estratigráficos; y la variabilidad accesible a través de contextos temporales de alta resolución. Esta última aproximación a la variabilidad se centra en el estudio de los diferentes comportamientos discernibles en un mismo nivel arqueológico. En este trabajo utilizaremos el nivel J como ejemplo de este tipo de análisis.L'Abric Romaní compta amb una potent seqüència del Paleolític Mitjà de qual, fins al moment, s'han excavat 13 nivells arqueològics. Aquests nivells mostren un patró d'ocupació basat en l'aparició d'espais domèstics entorn a fogars en els quals es concentren la major part de les activitats, especialment les relacionades amb el processament dels recursos lítics. Aquest patró permet caracteritzar l'Abric Romaní com un espai residencial, fet que és fonamental per entendre el registre arqueològic i el comportament tècnic. La variabilitat dels conjunts lítics s'ha tractat des d'una triple perspectiva, relacionada amb les diferents escales temporals a les quals és possible accedir a través de la metodologia arqueològica: la variabilitat que reflecteix processos de llarga duració i que s'expressa en els canvis que es produeixen al llarg de la seqüència; la variabilitat en l'interior del conjunt lític definit a partir de criteris estratigràfics; i la variabilitat accessible a través de contextos temporals d'alta resolució. Aquesta última aproximació a la variabilitat se centra en l'estudi dels diferents comportaments discernibles en un mateix nivell arqueològic. En aquest treball utilitzarem el nivell J com a exemple d'aquest tipus d'anàlisi.L'Abric Romaní compte avec une puissante séquence du Paléolithique Moyen dont, actuellement, ont uniquement été fouillés 13 niveaux archéologiques. Ces niveaux montrent un patron d'occupation basé sur l'apparition d'espaces domestiques autour des foyers dans lesquels se concentrent la plupart des activités, spécialement celles qui sont en relation avec la taille des ressources lithiques. Ce patron permet de caractériser l'Abri Romaní comme espace résidentiel, ce qui est fondamental pour comprendre le registre archéologique et le comportement technique. La variabilité des ensembles lithiques a été traitée suivant une triple perspective, mise en relation avec les différentes échelles temporelles auxquelles il est possible d'y accéder par la méthodologie archéologique: la variabilité qui montre des processus de longue durée et qui se donne par les changements produits tout le long de la séquence ; la variabilité à l'intérieur de l'ensemble lithique défini suivant des critères stratigraphiques ; et la variabilité accessible à partir des contextes temporels d'haute résolution. Cette dernière approche à la variabilité se centre sur l'étude des différents comportements discernables dans un même niveau archéologique. Dans ce travail, on utilisera le niveau J comme exemple de ce type d'analyse.Abric Romani contains a thick Middle Palaeolithic sequence of which 13 archaeological levels have been excavated so far. Occupation patterns in these levels are organized in domestic spaces around hearths in which most of activities are concentrated, especially those concerning the management of lithic material. This pattern portrays Abric Romani as a residential space, and that is essential to understanding its archaeological record and technical behaviour. Variability of the lithic assemblages has been assessed according to three different temporal scales feasible of being investigated with archaeological methods; variability in long term scales, as shown by changes throughout the sequence; variability in lithic assemblages within a single stratigraphic level; and variability in high resolution temporal contexts. The latter is approached through the study of different behaviours detected within the same archaeological level. In this paper, level J will be used as a case study to tackle this type of analysis

Datos fenológicos de floración de algunas especies leñosas de la duna del Faro de Trafalgar (Barbate, Cádiz)

Datos fenológicos de floración de algunas especies leñosas de la duna del Faro de Trafalgar (Barbate, Cádiz). En este trabajo se ha estudiado la composición florística y algunos aspectos del comportamiento fenológico de floración de algunas especies del matorral leñoso existente en una duna fija costera del sur de la Península Ibérica. En la comunidad de vegetación leñosa de la duna del Faro de Trafalgar se desarrollan procesos de floración a lo largo de todo el año, observándose un máximo en primavera (Marzo-Abril), que corresponde a la época de mayor disponibilidad de recursos y climatología más favorable. En el verano se produce una regresión en la producción de flores, aunque sin llegar a desaparecer, hasta alcanzarse otro máximo en otoño, aunque de menor magnitud y duración que en primavera. En los meses invernales muchos matorrales presentan floración, hecho por otra parte frecuente en otras comunidades de matorrales mediterráneos

On existence of trends applicable to thermoeconomic optimisation of combined cycle gas turbine power plants

This paper aims at the influence of the nominal power on the design configuration of combined cycle gas turbine (CCGT) power plants. This is achieved by means of a thermoeconomic model aimed at the minimisation of the power plant cost. The present work starts with the establishment of trends in existing commercial gas turbines. Based on these, other trends are found for the design of the whole CCGT, leading to the assessment of the most suitable heat recovery steam generator type and the optimal design parameters. Finally, an analysis of the influence of fuel price on the design configuration is carried out. This serves two purposes: to observe the dependence of economic results with fuel prices and to determine whether fuel price variations might influence the previously established trends in the CCGT design

Solid phase extraction of copper traces using poly (styrene-divinylbenzene) membrane disks modified with pyridoxal salicyloylhydrazone in water samples

A simple technique for the isolation, concentration and matrix simplification of Cu(II) ion in natural waters is proposed. This method has been developed using poly(styrene-divinylbenzene) membrane disks modified with the synthesized ligand pyridoxal salicyloylhydrazone (PSH). The retained ions on the disks were eluted with 10mL 1mol L 1 HNO3 and measured by flame atomic absorption spectrometry at 324.8nm. The influence of pH, amount of ligand, type and amount of eluent for the stripping of copper ion from the membrane over extraction efficiency were evaluated. Extraction efficiencies 499% were obtained by elution of the disks with minimal amount of solvent with a preconcentration factor up to 100. The precision of the method for 10 replicate measurements of aqueous solutions containing 40 mg L 1 Cu(II) was 1.5% at significance level of 95%. The breakthrough volume for 5 mg of Cu(II) was found to be 1000mL and the detection limit of the method was 4ngL 1 of metalion. The present method was successfully applied to the extraction and determination of copper in lake and sea waters

Variabilidad de los conjuntos líticos en el Paleolítico Medio del Abric Romaní (Capellades, Barcelona)

L’Abric Romaní compta amb una potent seqüència del Paleolític Mitjà de qual, fins al moment, s’han excavat 13 nivells arqueològics. Aquests nivells mostren un patró d’ocupació basat en l’aparició d’espais domèstics entorn a fogars en els quals es concentren la major part de les activitats, especialment les relacionades amb el processament dels recursos lítics. Aquest patró permet caracteritzar l’Abric Romaní com un espai residencial, fet que és fonamental per entendre el registre arqueològic i el comportament tècnic. La variabilitat dels conjunts lítics s’ha tractat des d’una triple perspectiva, relacionada amb les diferents escales temporals a les quals és possible accedir a través de la metodologia arqueològica: la variabilitat que reflecteix processos de llarga duració i que s’expressa en els canvis que es produeixen al llarg de la seqüència; la variabilitat en l’interior del conjunt lític definit a partir de criteris estratigràfics; i la variabilitat accessible a través de contextos temporals d’alta resolució. Aquesta última aproximació a la variabilitat se centra en l’estudi dels diferents comportaments discernibles en un mateix nivell arqueològic. En aquest treball utilitzarem el nivell J com a exemple d’aquest tipus d’anàlisi.Abric Romani contains a thick Middle Palaeolithic sequence of which 13 archaeological levels have been excavated so far. Occupation patterns in these levels are organized in domestic spaces around hearths in which most of activities are concentrated, especially those concerning the management of lithic material. This pattern portrays Abric Romani as a residential space, and that is essential to understanding its archaeological record and technical behaviour. Variability of the lithic assemblages has been assessed according to three different temporal scales feasible of being investigated with archaeological methods; variability in long term scales, as shown by changes throughout the sequence; variability in lithic assemblages within a single stratigraphic level; and variability in high resolution temporal contexts. The latter is approached through the study of different behaviours detected within the same archaeological level. In this paper, level J will be used as a case study to tackle this type of analysis.El Abric Romaní cuenta con una potente secuencia del Paleolítico Medio de la que hasta el momento se han excavado 13 niveles arqueológicos. Estos niveles muestran un patrón de ocupación basado en la aparición de espacios domésticos en torno a hogares en los que se concentra la mayor parte de las actividades, especialmente las relacionadas con el procesamiento de los recursos líticos. Este patrón permite caracterizar el Abric Romaní como un espacio residencial, lo que es fundamental para entender el registro arqueológico y el comportamiento técnico. La variabilidad de los conjuntos líticos se ha abordado desde una triple perspectiva, relacionada con las diferentes escalas temporales a las que es posible acceder a través de la metodología arqueológica: la variabilidad que refleja procesos de larga duración y que se expresa en los cambios que se producen a lo largo de la secuencia; la variabilidad en el interior de conjunto lítico definido a partir de criterios estratigráficos; y la variabilidad accesible a través de contextos temporales de alta resolución. Esta última aproximación a la variabilidad se centra en el estudio de los diferentes comportamientos discernibles en un mismo nivel arqueológico. En este trabajo utilizaremos el nivel J como ejemplo de este tipo de análisis

Monitoring and preliminary analysis of the natural responses recorded in a poorly accessible streambed spring located at a fluviokarstic gorge in Southern Spain

The analysis of natural responses (hydrodynamic, hydrothermal and hydrochemical) of karst springs is a well-established approach to provide insights into the hydrogeological functioning of the aquifers that they drain. However, a suitable monitoring program of these responses are often difficult to launch in poorly accessible streambed springs, due to the mixing between surface water and groundwater, in addition to topographic impediments. This work describes the installation procedure of the measurement equipment and the preliminary hydrogeological dataset collected at the Charco del Moro spring (Southern Spain) during one year. This outlet emerges 5 m below water surface, at the bottom of a partially flooded 20 - 200 m deep and 2 km long gorge, eroded by the Guadiaro River streamflow. It is considered the largest discharge point in the region, draining groundwater from northern nearby carbonate outcrops, although its catchment area is not established yet. Continuous (hourly) monitoring of electrical conductivity, water temperature, turbidity and water level (discharge) reflects a high degree of heterogeneity in the duality of groundwater flow and storage dynamics, which is typical of karst conduit flow systemsUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

Addition of Immune Checkpoint Inhibitors to Chemotherapy vs Chemotherapy Alone as First-Line Treatment in Extensive-Stage Small-Cell Lung Carcinoma: A Systematic Review and Meta-Analysis

Introduction The addition of immune checkpoint inhibitors (ICIs) to conventional chemotherapy (CT) as first-line treatment improves survival in extensive-stage small-cell lung cancer (ES-SCLC). The aim of this meta-analysis was to determine the relative efficacy of first-line ICIs compared with CT in patients with ES-SCLC. Methods Two independent reviewers extracted relevant data according to PRISMA guidelines and assessed the risk of bias using the Cochrane Collaboration's risk-of-bias tool. Meta-analysis was conducted using random-effects models to calculate an average effect size for overall survival (OS), progression-free survival (PFS), and safety outcomes in the overall populations and clinically relevant subgroups. Results A literature search of PubMed and Embase was performed. Six randomized controlled clinical trials (IMpower133, CHECKMATE-451, CASPIAN, KEYNOTE-604, and phase II and III ipilimumab plus CT trials) with a total of 3757 patients were included. Compared with CT alone, ICIs plus CT showed a favourable effect on OS (hazard ratio [HR] 0.85; 95% confidence intervals [CI] 0.79–0.96) and PFS (HR 0.78; 95% CI 0.72–0.83) but a non-significant increase in the risk of experiencing any adverse event (relative risk, 1.05; 95% CI 0.99–1.11). The estimated HR for OS favoured ICI combinations in all planned subgroups according to age (< 65 years/≥ 65 years), sex (men/women), and ECOG performance status (0/1). Analysis by specific ICI revealed significant improvements in OS only for atezolizumab + CT (HR 1.36; 95% CI 1.09–1.69) and durvalumab + CT (HR 1.35; 95% CI 1.12–1.62) compared with CT alone. Conclusion Combining anti-programmed cell death ligand 1 antibodies with platinum/etoposide is a superior therapeutic approach compared to CT alone for the first-line treatment of patients with ES-SCLC