700 research outputs found

    The Statistical Mapping of Magnetosheath Plasma Properties Based on THEMIS Measurements in the Magnetosheath Interplanetary Medium Reference Frame

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    The magnetosheath operates as a natural filter between the solar wind and the magnetospheric plasma. As a result of this, the magnetosheath plays a crucial role in the plasma momentum and energy transport from the interplanetary medium into the magnetosphere. Statistical studies of the magnetosheath are difficult due to the dynamic nature of the terrestrial bow shock and the magnetopause. As a result of this, the spatial and temporal dependence of magnetosheath plasma properties under varying solar wind conditions is still not completely understood. We present a study of magnetosheath plasma properties using 5 years of THEMIS and OMNI data to produce statistical maps of fundamental magnetosheath plasma properties. The magnetosheath interplanetary medium reference frame is applied to present data in a normalized reference frame which accounts for both boundary and orbital motion. The statistical maps are compared with the MHD runs from the CCMC-BATS-R-US model which agree favorably. The results are also used to investigate the presence of any magnetosheath plasma parameter asymmetries and their possible causes

    Study of guidance techniques for aerial application of agricultural compounds

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    Candidate systems were identified for evaluation of suitability in meeting specified accuracy requirements for a swath guidance system in an agriculture aircraft. Further examination reduced the list of potential candidates to a single category, i.e., transponder type systems, for detailed evaluation. Within this category three systems were found which met the basic accuracy requirements of the work statement. The Flying Flagman, the Electronic Flagging and the Raydist Director System. In addition to evaluating the systems against the specified requirements, each system was compared with the other two systems on a relative basis. The conclusions supported by the analyses show the Flying Flagman system to be the most suitable system currently available to meet the requirements

    Ion-Scale Wave Properties and Enhanced Ion Heating Across the Low-Latitude Boundary Layer During Kelvin-Helmholtz Instability

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    In the Earth\u27s magnetosphere, the magnetotail plasma sheet ions are much hotter than in the shocked solar wind. On the dawn sector, the cold-component ions are more abundant and hotter by 30–40% when compared to the dusk sector. Recent statistical studies of the flank magnetopause and magnetosheath have shown that the level of temperature asymmetry of the magnetosheath is unable to account for this, so additional physical mechanisms must be at play, either at the magnetopause or plasma sheet that contributes to this asymmetry. In this study, we perform a statistical analysis on the ion-scale wave properties in the three main plasma regimes common to flank magnetopause boundary crossings when the boundary is unstable to Kelvin-Helmholtz instability (KHI): hot and tenuous magnetospheric, cold and dense magnetosheath, and mixed (Hasegawa et al., 2004). These statistics of ion-scale wave properties are compared to observations of fast magnetosonic wave modes that have recently been linked to Kelvin-Helmholtz (KH) vortex centered ion heating (Moore et al., 2016). The statistical analysis shows that during KH events there is enhanced nonadiabatic heating calculated during ion scale wave intervals when compared to non-KH events. This suggests that during KH events there is more free energy for ion-scale wave generation, which in turn can heat ions more effectively when compared to cases when KH waves are absent. This may contribute to the dawn favored temperature asymmetry of the plasma sheet; recent studies suggest KH waves favor the dawn flank during Parker-Spiral interplanetary magnetic field

    Dispersion of low frequency plasma waves upstream of the quasi-perpendicular terrestrial bow shock

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    Low frequency waves in the foot of a supercritical quasi-perpendicular shock front have been observed since the very early in situ observations of the terrestrial bow shock (Guha et al., 1972). The great attention that has been devoted to these type of waves since the first observations is explained by the key role attributed to them in the processes of energy redistribution in the shock front by various theoretical models. In some models, these waves play the role of the intermediator between the ions and electrons. It is assumed that they are generated by plasma instability that exist due to the counter-streaming flows of incident and reflected ions. In the second type of models, these waves result from the evolution of the shock front itself in the quasi-periodic process of steepening and overturning of the magnetic ramp. However, the range of the observed frequencies in the spacecraft frame are not enough to distinguish the origin of the observed waves. It also requires the determination of the wave vectors and the plasma frame frequencies. Multipoint measurements within the wave coherence length are needed for an ambiguous determination of the wave vectors. In the main multi-point missions such as ISEE, AMPTE, Cluster and THEMIS, the spacecraft separation is too large for such a wave vector determination and therefore only very few case studies are published (mainly for AMPTE UKS AMPTE IRM pair). Here we present the observations of upstream low frequency waves by the Cluster spacecraft which took place on 19 February 2002. The spacecraft separation during the crossing of the bow shock was small enough to determine the wave vectors and allowed the identification of the plasma wave dispersion relation for the observed waves. Presented results are compared with whistler wave dispersion and it is shown that contrary to previous studies based on the AMPTE data, the phase velocity in the shock frame is directed downstream. The consequences of this finding for both types of models that were developed to explain the generation of these waves are discussed

    The case for early use of rapid whole-genome sequencing in management of critically ill infants: late diagnosis of Coffin-Siris syndrome in an infant with left congenital diaphragmatic hernia, congenital heart disease, and recurrent infections.

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    Congenital diaphragmatic hernia (CDH) results from incomplete formation of the diaphragm leading to herniation of abdominal organs into the thoracic cavity. CDH is associated with pulmonary hypoplasia, congenital heart disease, and pulmonary hypertension. Genetically, it is associated with aneuploidies, chromosomal copy-number variants, and single gene mutations. CDH is the most expensive noncardiac congenital defect. Management frequently requires implementation of extracorporeal membrane oxygenation (ECMO), which increases management expenditures 2.4-3.5-fold. The cost of management of CDH has been estimated to exceed $250 million per year. Despite in-hospital survival of 80%-90%, current management is imperfect, as a great proportion of surviving children have long-term functional deficits. We report the case of a premature infant prenatally diagnosed with CDH and congenital heart disease, who had a protracted and complicated course in the intensive care unit with multiple surgical interventions, including postcardiac surgery ECMO, gastrostomy tube placement with Nissen fundoplication, tracheostomy for respiratory failure, recurrent infections, and developmental delay. Rapid whole-genome sequencing (rWGS) identified a de novo, likely pathogenic, c.3096_ 3100delCAAAG (p.Lys1033Argfs*32) variant in ARID1B, providing a diagnosis of Coffin-Siris syndrome. Her parents elected palliative care and she died later that day

    Magnetosheath control of solar wind-magnetosphere coupling efficiency

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    We examine the role of the magnetosheath in solar wind-magnetosphere-ionosphere coupling using the Time History of Events and Macroscale Interactions during Substorms plasma and magnetic field observations in the magnetosheath together with OMNI solar wind data and auroral electrojet recordings from the International Monitor for Auroral Geomagnetic Effects (IMAGE) magnetometer chain. We demonstrate that the electric field and Poynting flux reaching the magnetopause are not linear functions of the electric field and Poynting flux observed in the solar wind: the electric field and Poynting flux at the magnetopause during higher driving conditions are lower than those predicted from a linear function. We also show that the Poynting flux normal to the magnetopause is linearly correlated with the directly driven part of the auroral electrojets in the ionosphere. This indicates that the energy entering the magnetosphere in the form of the Poynting flux is directly responsible for driving the electrojets. Furthermore, we argue that the polar cap potential saturation discussed in the literature is associated with the way solar wind plasma gets processed during the bow shock crossing and motion within the magnetosheath.Peer reviewe

    Statistical analysis of mirror mode waves in sheath regions driven by interplanetary coronal mass ejection

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    We present a comprehensive statistical analysis of mirror mode waves and the properties of their plasma surroundings in sheath regions driven by interplanetary coronal mass ejection (ICME). We have constructed a semi-automated method to identify mirror modes from the magnetic field data. We analyze 91 ICME sheath regions from January 1997 to April 2015 using data from the Wind spacecraft. The results imply that similarly to planetary magnetosheaths, mirror modes are also common structures in ICME sheaths. However, they occur almost exclusively as dip-like structures and in mirror stable plasma. We observe mirror modes throughout the sheath, from the bow shock to the ICME leading edge, but their amplitudes are largest closest to the shock. We also find that the shock strength (measured by Alfven Mach number) is the most important parameter in controlling the occurrence of mirror modes. Our findings suggest that in ICME sheaths the dominant source of free energy for mirror mode generation is the shock compression. We also suggest that mirror modes that are found deeper in the sheath are remnants from earlier times of the sheath evolution, generated also in the vicinity of the shock.Peer reviewe

    A comparison of beliefs about exercise during pregnancy between Chinese and Australian pregnant women

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    Background: Despite the well-established benefits of exercise during pregnancy, many women remain inactive. This may be related, in part, to women's beliefs about exercise in pregnancy, which are likely influenced by cultural background. Accordingly, the aim of this study was to compare attitudes, subjective norms, and perceived behavioural control toward exercise, together with current levels of exercise participation between Chinese and Australian women during pregnancy. A second aim was to determine the extent to which these factors predict intention to exercise within a Theory of Planned Behaviour framework. Methods: Pregnant women (22 ± 2 weeks of gestation) living in China (n = 240) and Australia (n = 215) completed a questionnaire designed to assess a) maternal beliefs regarding the importance of exercise in relation to other health behaviours, b) attitudes, subjective norms, perceived behavioural control and intentions toward exercise, and c) current levels of physical activity. One-way analyses of variance were used to compare the demographics, maternal beliefs, attitudes, subjective norms, perceived behavioural control, intentions to exercise, and current physical activity levels between the Chinese and Australian samples. Structural equation modelling was used to determine which factors predicted intention to exercise in the two samples. Results: Australian women reported higher levels of current exercise and intentions to exercise in the next four weeks of pregnancy compared with Chinese women. These observations were associated with higher instrumental attitudes, ratings of subjective norm, and perceived behavioural control toward exercise in the Australian women. Instrumental attitudes and perceived behavioural control predicted intention to exercise in the Australian women, while perceived behavioural control was the only predictor of intentions to exercise in the Chinese sample. Conclusions: Beliefs, attitudes, barriers and intentions towards exercise during pregnancy differ between cultures. Understanding these differences may assist in the design of exercise interventions to maximise exercise adherence and lifelong physical activity patterns

    Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established

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    Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics. In addition there are periodic outbreaks in domestic poultry, horses, pigs, dogs, and cats. Infections of domestic birds can be fatal for the birds and their human contacts. Control in man operates through vaccines and antivirals, but both have their limitations. In the search for an alternative treatment we have focussed on defective interfering (DI) influenza A virus. Such a DI virus is superficially indistinguishable from a normal virus but has a large deletion in one of the eight RNAs that make up the viral genome. Antiviral activity resides in the deleted RNA. We have cloned one such highly active DI RNA derived from segment 1 (244 DI virus) and shown earlier that intranasal administration protects mice from lethal disease caused by a number of different influenza A viruses. A more cogent model of human influenza is the ferret. Here we found that intranasal treatment with a single dose of 2 or 0.2 µg 244 RNA delivered as A/PR/8/34 virus particles protected ferrets from disease caused by pandemic virus A/California/04/09 (A/Cal; H1N1). Specifically, 244 DI virus significantly reduced fever, weight loss, respiratory symptoms, and infectious load. 244 DI RNA, the active principle, was amplified in nasal washes following infection with A/Cal, consistent with its amelioration of clinical disease. Animals that were treated with 244 DI RNA cleared infectious and DI viruses without delay. Despite the attenuation of infection and disease by DI virus, ferrets formed high levels of A/Cal-specific serum haemagglutination-inhibiting antibodies and were solidly immune to rechallenge with A/Cal. Together with earlier data from mouse studies, we conclude that 244 DI virus is a highly effective antiviral with activity potentially against all influenza A subtypes
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