Oscillatory and Asymptotic Properties of the Solutions of a Class of Operator-Differential Equations

Sin resume

Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2)

BACKGROUND: Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control. METHODS: Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million adults (age 15-99 years) and 75,000 children (age 0-14 years) diagnosed with cancer during 1995-2009 and followed up to Dec 31, 2009, or later. We looked at cancers of the stomach, colon, rectum, liver, lung, breast (women), cervix, ovary, and prostate in adults, and adult and childhood leukaemia. Standardised quality control procedures were applied; errors were corrected by the registry concerned. We estimated 5-year net survival, adjusted for background mortality in every country or region by age (single year), sex, and calendar year, and by race or ethnic origin in some countries. Estimates were age-standardised with the International Cancer Survival Standard weights. FINDINGS: 5-year survival from colon, rectal, and breast cancers has increased steadily in most developed countries. For patients diagnosed during 2005-09, survival for colon and rectal cancer reached 60% or more in 22 countries around the world; for breast cancer, 5-year survival rose to 85% or higher in 17 countries worldwide. Liver and lung cancer remain lethal in all nations: for both cancers, 5-year survival is below 20% everywhere in Europe, in the range 15-19% in North America, and as low as 7-9% in Mongolia and Thailand. Striking rises in 5-year survival from prostate cancer have occurred in many countries: survival rose by 10-20% between 1995-99 and 2005-09 in 22 countries in South America, Asia, and Europe, but survival still varies widely around the world, from less than 60% in Bulgaria and Thailand to 95% or more in Brazil, Puerto Rico, and the USA. For cervical cancer, national estimates of 5-year survival range from less than 50% to more than 70%; regional variations are much wider, and improvements between 1995-99 and 2005-09 have generally been slight. For women diagnosed with ovarian cancer in 2005-09, 5-year survival was 40% or higher only in Ecuador, the USA, and 17 countries in Asia and Europe. 5-year survival for stomach cancer in 2005-09 was high (54-58%) in Japan and South Korea, compared with less than 40% in other countries. By contrast, 5-year survival from adult leukaemia in Japan and South Korea (18-23%) is lower than in most other countries. 5-year survival from childhood acute lymphoblastic leukaemia is less than 60% in several countries, but as high as 90% in Canada and four European countries, which suggests major deficiencies in the management of a largely curable disease. INTERPRETATION: International comparison of survival trends reveals very wide differences that are likely to be attributable to differences in access to early diagnosis and optimum treatment. Continuous worldwide surveillance of cancer survival should become an indispensable source of information for cancer patients and researchers and a stimulus for politicians to improve health policy and health-care systems

Existence and asymptotic behavior of the positive solutions of neutral impulsive differential equations

In this article we consider first order neutral impulsive differential equations with constant coefficients and constant delays. We study the asymptotic behavior of the eventually positive solutions of these equations and establish necessary and sufficient conditions for the existence of such solutions.Розглянуто нейтральнi диференцiальнi рiвняння першого порядку з iмпульсною дiєю, сталими коефiцiєнтами та сталими запiзненнями. Вивчено асимптотичну поведiнку евентуально додатних розв’язкiв цих рiвнянь та знайдено достатнi умови їх iснування

Sufficient conditions for oscillation of solutions of first order neutral delay impulsive differential equations with constant coefficients

This paper is dealing with the oscillatory properties of first order neutral delay impulsive differential equations and the corresponding inequalities with constant coefficients. The established sufficient conditions ensure oscillation of every solution of this type of the equations.Розглянуто осциляцiйнi властивостi розв’язкiв диференцiальних рiвнянь першого порядку зi сталими коефiцiєнтами та нейтральним запiзненням iмпульсної дiї та вiдповiдних до них нерiвностей. Знайденi умови є достатнiми для того, щоб кожний розв’язок рiвняння такого типу був осциляцiйним

Make me yours: The psychodynamics of seduction through works of art

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Multi-directional weighted interpolation for wi-fi localisation

© Springer International Publishing Switzerland 2014. The rise in popularity of unmanned autonomous vehicles (UAV) has created a need for accurate positioning systems. Due to the indoor limitations of the Global Positioning System (GPS), research has focused on other technologies which could be used in this landscape with Wi-Fi localisation emerging as a popular option. When implementing such a system, it is necessary to find an equilibrium between the desired level of final precision, and the time and money spent training the system. We propose Multi-Directional Weighted Interpolation (MDWI), a probabilistic-based weighting mechanism to predict unseen locations. Our results show that MDWI uses half the number of training points whilst increasing accuracy by up to 24%

Analyzing multiple endpoints in clinical trials of pain treatments: IMMPACT recommendations

The increasing complexity of randomized clinical trials and the practice of obtaining a wide variety of measurements from study participants have made the consideration of multiple endpoints a critically important issue in the design, analysis, and interpretation of clinical trials. Failure to consider important outcomes can limit the validity and utility of clinical trials; specifying multiple endpoints for the evaluation of treatment efficacy, however, can increase the rate of false positive conclusions about the efficacy of a treatment. We describe the use of multiple endpoints in the design, analysis, and interpretation of pain clinical trials, and review available strategies and methods for addressing multiplicity. To decrease the probability of a Type I error (i.e., the likelihood of obtaining statistically significant results by chance) in pain clinical trials, the use of gatekeeping procedures and other methods that correct for multiple analyses is recommended when a single primary endpoint does not adequately reflect the overall benefits of treatment. We emphasize the importance of specifying in advance the outcomes and clinical decision rule that will serve as the basis for determining that a treatment is efficacious and the methods that will be used to control the overall Type I error rate

Peering into microscale details of mountain winds

A grand challenge from the wind energy industry is to provide reliable forecasts on mountain winds several hours in advance at microscale (similar to 100 m) resolution. This requires better microscale wind-energy physics included in forecasting tools, for which field observations are imperative. While mesoscale (similar to 1 km) measurements abound, microscale processes are not monitored in practice nor do plentiful measurements exist at this scale. After a decade of preparation, a group of European and U.S. collaborators conducted a field campaign during 1 May-15 June 2017 in Vale Cobrao in central Portugal to delve into microscale processes in complex terrain. This valley is nestled within a parallel double ridge near the town of Perdigao with dominant wind climatology normal to the ridges, offering a nominally simple yet natural setting for fundamental studies. The dense instrument ensemble deployed covered a similar to 4 km x 4 km swath horizontally and similar to 10 km vertically, with measurement resolutions of tens of meters and seconds. Meteorological data were collected continuously, capturing multiscale flow interactions from synoptic to microscales, diurnal variability, thermal circulation, turbine wake and acoustics, waves, and turbulence. Particularly noteworthy are the extensiveness of the instrument array, space-time scales covered, use of leading-edge multiple-lidar technology alongside conventional tower and remote sensors, fruitful cross-Atlantic partnership, and adaptive management of the campaign. Preliminary data analysis uncovered interesting new phenomena. All data are being archived for public use