Future directions in international financial integration research. A crowdsourced perspective

This paper is the result of a crowdsourced effort to surface perspectives on the present and future direction of international finance. The authors are researchers in financial economics who attended the INFINITI 2017 conference in the University of Valencia in June 2017 and who participated in the crowdsourcing via the Overleaf platform. This paper highlights the actual state of scientific knowledge in a multitude of fields in finance and proposes different directions for future research

The comparative responsiveness of Hospital Universitario Princesa Index and other composite indices for assessing rheumatoid arthritis activity

Objective To evaluate the responsiveness in terms of correlation of the Hospital Universitario La Princesa Index (HUPI) comparatively to the traditional composite indices used to assess disease activity in rheumatoid arthritis (RA), and to compare the performance of HUPI-based response criteria with that of the EULAR response criteria. Methods Secondary data analysis from the following studies: ACT-RAY (clinical trial), PROAR (early RA cohort) and EMECAR (pre-biologic era long term RA cohort). Responsiveness was evaluated by: 1) comparing change from baseline (Delta) of HUPI with Delta in other scores by calculating correlation coefficients; 2) calculating standardised effect sizes. The accuracy of response by HUPI and by EULAR criteria was analyzed using linear regressions in which the dependent variable was change in global assessment by physician (Delta GDA-Phy). Results Delta HUPI correlation with change in all other indices ranged from 0.387 to 0.791); HUPI's standardized effect size was larger than those from the other indices in each database used. In ACT-RAY, depending on visit, between 65 and 80% of patients were equally classified by HUPI and EULAR response criteria. However, HUPI criteria were slightly more stringent, with higher percentage of patients classified as non-responder, especially at early visits. HUPI response criteria showed a slightly higher accuracy than EULAR response criteria when using Delta GDA-Phy as gold standard. Conclusion HUPI shows good responsiveness in terms of correlation in each studied scenario (clinical trial, early RA cohort, and established RA cohort). Response criteria by HUPI seem more stringent than EULAR''s

Programming methodology for multi-axis CNC woodworking machining center for advanced manufacturing based on STEP-NC

The paper proposes a programming methodology for advanced manufacturing based on STEP-NC, a compliant to multi-axis CNC woodworking machining center. The equivalent virtual machine in the CAD/CAM, STEP-NC environment, is developed as a part of a programming system for considered CNC woodworking machining center. STEP-NC aims to provide a digital thread for CNC manufacturing running in the STEP-NC System world via the Internet that can enable advanced e-Manufacturing. Virtual machine as a digital twin is configured and implemented into the control system based on LinuxCNC, but configured virtual machine as a Web interface based on STEP-NC, also. The developed methodology is validated through machining simulation using the configured digital twin in the control system and machining experiments on the real machine

Phosphorus-to-phospholipid conversion factors for crude and degummed sunflower oils

Phospholipid composition and phosphorus content of several crude and degummed sunflower oils were measured in order to compare theoretical and experimental factors used to convert phosphorus content to phospholipid content. Differences in phospholipid content between sunflower oils obtained by different extraction and degumming methods were also considered. From FA and phospholipid compositions, average theoretical conversion factors of 24.7 and 23.0 were found for crude and degummed sunflower oils, respectively. The experimental conversion factor for degummed oils was in good agreement with the theoretical value. In contrast, fitted experimental factors were significantly lower for crude oils. The differences could be attributed to phosphorus from sources other than phospholipids and to the presence of minor phospholipids not quantified by chromatographic analysis. The relative phospholipid concentrations of oils depended on the method of extraction and the type of degumming. Solvent-extracted oils had a higher total phospholipid content, being generally more concentrated in PC and PE. The content of nonhydratable phospholipids was relatively low; acid or enzymatic degumming removed 40 to 70% of these phospholipids.Fil: Carelli Albarracin, Amalia Antonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaFil: Ceci, Liliana Noemí. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaFil: Crapiste, Guillermo Hector. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentin

Sensitivity and specificity of a quality of life questionnaire Qualeffo-41

ISPOR 18th Annual International Meeting Research Abstract