461 research outputs found

    Remote Sensing of Snow in the Solar Spectrum: Experiments in the French Alps.

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    Two experiments were perfonned irliApril and December 1992 in the French Alps using simultaneous relnote sensing and ground truth data. Snow grain site and soot content of samples collected in thefield were measured. The Landsat thematic mapper (TM) sensor was used because it has a good spatial resolution, a middle infrared channel which is sensitive to grain size and a thermal infraredchannel. Firstj the reflectance data were compared with the theoretical results obtained from a bidirectional reflectance model. Then, some remote sehstng-derived snow parameters wbre comparediWith the outpllt ofa snow metamorphism model (CROCUS),viz., lower elevation of the snowcover, lhe surface grl1in size and the surface temperature. A digital elevation model was used to obtain thelocal incidenc:f angles and the elevation of each snow pixel. The pixels were then grouped according to CROCUS classification (range, elevation, slope, and orientation) and the mean snow chart;cheracteristicsfor each class were .compared with the tROCUS results. The lower limit of snow and the surface grain size derived from TM data were compared favourably with the model results. Larger differences werefound for the temperature, because it varies rapidly and is very sensitive to shadowing by the snrrounding mountains and also because its remote measurement is dependent on atmospheric conditions

    Ethanol application at veraison decreases acidity in Cabernet Sauvignon grapes

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    Research NoteSpraying ethanol (5 % v/v in water) onto grape clusters at mid-veraison led to a 30 % drop in the malic acid concentration at harvest. As a consequence, titratable acidity also dropped by 10 %. The concentration of tartaric acid did not change significantly. The mode of action of ethanol on malic acid metabolism is discussed.

    Punctual Hilbert Schemes and Certified Approximate Singularities

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    In this paper we provide a new method to certify that a nearby polynomial system has a singular isolated root with a prescribed multiplicity structure. More precisely, given a polynomial system f =(f_1,,f_N)C[x_1,,x_n]N=(f\_1, \ldots, f\_N)\in C[x\_1, \ldots, x\_n]^N, we present a Newton iteration on an extended deflated system that locally converges, under regularity conditions, to a small deformation of ff such that this deformed system has an exact singular root. The iteration simultaneously converges to the coordinates of the singular root and the coefficients of the so called inverse system that describes the multiplicity structure at the root. We use α\alpha-theory test to certify the quadratic convergence, and togive bounds on the size of the deformation and on the approximation error. The approach relies on an analysis of the punctual Hilbert scheme, for which we provide a new description. We show in particular that some of its strata can be rationally parametrized and exploit these parametrizations in the certification. We show in numerical experimentation how the approximate inverse system can be computed as a starting point of the Newton iterations and the fast numerical convergence to the singular root with its multiplicity structure, certified by our criteria.Comment: International Symposium on Symbolic and Algebraic Computation, Jul 2020, Kalamata, Franc

    Defining and cataloging exoplanets: The exoplanet.eu database

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    We describe an online database for extra-solar planetary-mass candidates, updated regularly as new data are available. We first discuss criteria for the inclusion of objects in the catalog: "definition" of a planet and several aspects of the confidence level of planet candidates. {\bf We are led to point out the conflict between sharpness of belonging or not to a catalogue and fuzziness of the confidence level.} We then describe the different tables of extra-solar planetary systems, including unconfirmed candidates (which will ultimately be confirmed, or not, by direct imaging). It also provides online tools: histogrammes of planet and host star data, cross-correlations between these parameters and some VO services. Future evolutions of the database are presented.Comment: Accepted in Astronomy and Astrophysics (revised version

    Adverse childhood experiences and premature all-cause mortality

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    Events causing stress responses during sensitive periods of rapid neurological development in childhood may be early determinants of all-cause premature mortality. Using a British birth cohort study of individuals born in 1958, the relationship between adverse childhood experiences (ACE) and mortality ≤50 year was examined for men (n = 7,816) and women (n = 7,405) separately. ACE were measured using prospectively collected reports from parents and the school: no adversities (70 %); one adversity (22 %), two or more adversities (8 %). A Cox regression model was carried out controlling for early life variables and for characteristics at 23 years. In men the risk of death was 57 % higher among those who had experienced 2+ ACE compared to those with none (HR 1.57, 95 % CI 1.13, 2.18, p = 0.007). In women, a graded relationship was observed between ACE and mortality, the risk increasing as ACE accumulated. Women with one ACE had a 66 % increased risk of death (HR 1.66, 95 % CI 1.19, 2.33, p = 0.003) and those with ≥2 ACE had an 80 % increased risk (HR 1.80, 95 % CI 1.10, 2.95, p = 0.020) versus those with no ACE. Given the small impact of adult life style factors on the association between ACE and premature mortality, biological embedding during sensitive periods in early development is a plausible explanatory mechanism

    From error bounds to the complexity of first-order descent methods for convex functions

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    This paper shows that error bounds can be used as effective tools for deriving complexity results for first-order descent methods in convex minimization. In a first stage, this objective led us to revisit the interplay between error bounds and the Kurdyka-\L ojasiewicz (KL) inequality. One can show the equivalence between the two concepts for convex functions having a moderately flat profile near the set of minimizers (as those of functions with H\"olderian growth). A counterexample shows that the equivalence is no longer true for extremely flat functions. This fact reveals the relevance of an approach based on KL inequality. In a second stage, we show how KL inequalities can in turn be employed to compute new complexity bounds for a wealth of descent methods for convex problems. Our approach is completely original and makes use of a one-dimensional worst-case proximal sequence in the spirit of the famous majorant method of Kantorovich. Our result applies to a very simple abstract scheme that covers a wide class of descent methods. As a byproduct of our study, we also provide new results for the globalization of KL inequalities in the convex framework. Our main results inaugurate a simple methodology: derive an error bound, compute the desingularizing function whenever possible, identify essential constants in the descent method and finally compute the complexity using the one-dimensional worst case proximal sequence. Our method is illustrated through projection methods for feasibility problems, and through the famous iterative shrinkage thresholding algorithm (ISTA), for which we show that the complexity bound is of the form O(qk)O(q^{k}) where the constituents of the bound only depend on error bound constants obtained for an arbitrary least squares objective with 1\ell^1 regularization

    LRP-1 Promotes Cancer Cell Invasion by Supporting ERK and Inhibiting JNK Signaling Pathways

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    Background: The low-density lipoprotein receptor-related protein-1 (LRP-1) is an endocytic receptor mediating the clearance of various extracellular molecules involved in the dissemination of cancer cells. LRP-1 thus appeared as an attractive receptor for targeting the invasive behavior of malignant cells. However, recent results suggest that LRP-1 may facilitate the development and growth of cancer metastases in vivo, but the precise contribution of the receptor during cancer progression remains to be elucidated. The lack of mechanistic insights into the intracellular signaling networks downstream of LRP-1 has prevented the understanding of its contribution towards cancer. Methodology/Principal Findings: Through a short-hairpin RNA-mediated silencing approach, we identified LRP-1 as a main regulator of ERK and JNK signaling in a tumor cell context. Co-immunoprecipitation experiments revealed that LRP-1 constitutes an intracellular docking site for MAPK containing complexes. By using pharmacological agents, constitutively active and dominant-negative kinases, we demonstrated that LRP-1 maintains malignant cells in an adhesive state that is favorable for invasion by activating ERK and inhibiting JNK. We further demonstrated that the LRP-1-dependent regulation of MAPK signaling organizes the cytoskeletal architecture and mediates adhesive complex turnover in cancer cells. Moreover, we found that LRP-1 is tethered to the actin network and to focal adhesion sites and controls ERK and JNK targeting to talin-rich structures. Conclusions: We identified ERK and JNK as the main molecular relays by which LRP-1 regulates focal adhesion disassembly of malignant cells to support invasion
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