3,520 research outputs found
Radial Distribution of the Mass-to-Luminosity Ratio in Spiral Galaxies and Massive Dark Cores
We derive radial profiles of the surface-mass-density for 19 spiral galaxies
directly from their high-resolution rotation curves. Using the corresponding
luminosity profiles, we obtain the radial distribution of the
mass-to-luminosity ratios () from the inner bulge ( a few 100 pc) to
the outer disk ( 2-10 kpc) for 11 galaxies (with inclination <
in order to reduce the influence of the interstellar extinction.
The s in the bulges of two galaxies with sufficient resolution, NGC 4527
and NGC 6946, are found to increase steeply toward the center at radii
100-500 pc at rates of 153 and 72 times per kpc, respectively. Some
other galaxies with fairly high resolution also show signs of an increase
toward the center. Such an increase may indicate the existence of a new
component, a ``massive dark core'', which may be an object linking the bulge
and a central black hole. Based on radial variations of the , we further
discuss the variation of the dark-mass fraction in spiral galaxies.Comment: Latex 19 pages, 30 ps figures. ApJ in pres
Quantum shot-noise at local tunneling contacts on mesoscopic multiprobe conductors
New experiments that measure the low-frequency shot-noise spectrum at local
tunneling contacts on mesoscopic structures are proposed. The current
fluctuation spectrum at a single tunneling tip is determined by local partial
densities of states. The current-correlation spectrum between two tunneling
tips is sensitive to non-diagonal density of states elements which are
expressed in terms of products of scattering states of the conductor. Thus such
an experiment permits to investigate correlations of electronic wave functions.
We present specific results for a clean wire with a single barrier and for
metallic diffusive conductors.Comment: 4 pages REVTeX, 2 figure
Spin accumulation induced resistance in mesoscopic ferromagnet/ superconductor junctions
We present a description of spin-polarized transport in mesoscopic
ferromagnet-superconductor (F/S) systems, where the transport is diffusive, and
the interfaces are transparent. It is shown that the spin reversal associated
with Andreev reflection generates an excess spin density close to the F/S
interface, which leads to a spin contact resistance. Expressions for the
contact resistance are given for two terminal and four terminal geometries. In
the latter the sign depends on the relative magnetization of the ferromagnetic
electrodes.Comment: RevTeX 10 pages, 4 figures, submitted to Phys.Rev. Let
The POINT-AGAPE survey II: An Unrestricted Search for Microlensing Events towards M31
An automated search is carried out for microlensing events using a catalogue
of 44554 variable superpixel lightcurves derived from our three-year monitoring
program of M31. Each step of our candidate selection is objective and
reproducible by a computer. Our search is unrestricted, in the sense that it
has no explicit timescale cut. So, it must overcome the awkward problem of
distinguishing long-timescale microlensing events from long-period stellar
variables. The basis of the selection algorithm is the fitting of the
superpixel lightcurves to two different theoretical models, using variable star
and blended microlensing templates. Only if microlensing is preferred is an
event retained as a possible candidate. Further cuts are made with regard to
(i) sampling, (ii) goodness of fit of the peak to a Paczynski curve, (iii)
consistency of the microlensing hypothesis with the absence of a resolved
source, (iv) achromaticity, (v) position in the colour-magnitude diagram and
(vi) signal-to-noise ratio. Our results are reported in terms of first-level
candidates, which are the most trustworthy, and second-level candidates, which
are possible microlensing but have lower signal-to-noise and are more
questionable. The pipeline leaves just 3 first-level candidates, all of which
have very short full-width half-maximum timescale (<5 days) and 3 second-level
candidates, which have timescales of 31, 36 and 51 days respectively. We also
show 16 third-level lightcurves, as an illustration of the events that just
fail the threshold for designation as microlensing candidates. They are almost
certainly mainly variable stars. Two of the 3 first-level candidates correspond
to known events (PA 00-S3 and PA 00-S4) already reported by the POINT-AGAPE
project. The remaining first-level candidate is new.Comment: 22 pages, 18 figures, MNRAS, to appea
Internal medicine specialists' attitudes towards working part-time: a comparison between 1996 and 2004
BACKGROUND: Although medical specialists traditionally hold negative views towards working part-time, the practice of medicine has evolved. Given the trend towards more part-time work and that there is no evidence that it compromises the quality of care, attitudes towards part-time work may have changed as well in recent years. The aim of this paper was to examine the possible changes in attitudes towards part-time work among specialists in internal medicine between 1996 and 2004. Moreover, we wanted to determine whether these attitudes were associated with individual characteristics (age, gender, investments in work) and whether attitudes of specialists within a partnership showed more resemblance than specialists' attitudes from different partnerships. METHODS: Two samples were used in this study: data of a survey conducted in 1996 and in 2004. After selecting internal medicine specialists working in general hospitals in The Netherlands, the sample consisted of 219 specialists in 1996 and 363 specialists in 2004. They were sent a questionnaire, including topics on the attitudes towards part-time work. RESULTS: Internal medicine specialists' attitudes towards working part-time became slightly more positive between 1996 and 2004. Full-time working specialists in 2004 still expressed concerns regarding the investments of part-timers in overhead tasks, the flexibility of task division, efficiency, communication and continuity of care. In 1996 gender was the only predictor of the attitude, in 2004 being a full- or a part-timer, age and the time invested in work were associated with this attitude. Furthermore, specialists' attitudes were not found to cluster much within partnerships. CONCLUSION: In spite of the increasing number of specialists working or preferring to work part-time, part-time practice among internal medicine specialists seems not to be fully accepted. The results indicate that the attitudes are no longer gender based, but are associated with age and work aspects such as the number of hours worked. Though there is little evidence to support them, negative ideas about the consequences of part-time work for the quality of care still exist. Policy should be aimed at removing the organisational difficulties related to part-time work and create a system in which part-time practice is fully integrated and accepted
Monitoring international migration flows in Europe. Towards a statistical data base combining data from different sources
The paper reviews techniques developed in demography, geography and statistics that are useful for bridging the gap between available data on international migration flows and the information required for policy making and research. The basic idea of the paper is as follows: to establish a coherent and consistent data base that contains sufficiently detailed, up-to-date and accurate information, data from several sources should be combined. That raises issues of definition and measurement, and of how to combine data from different origins properly. The issues may be tackled more easily if the statistics that are being compiled are viewed as different outcomes or manifestations of underlying stochastic processes governing migration. The link between the processes and their outcomes is described by models, the parameters of which must be estimated from the available data. That may be done within the context of socio-demographic accounting. The paper discusses the experience of the U.S. Bureau of the Census in combining migration data from several sources. It also summarizes the many efforts in Europe to establish a coherent and consistent data base on international migration.
The paper was written at IIASA. It is part of the Migration Estimation Study, which is a collaborative IIASA-University of Groningen project, funded by the Netherlands Organization for Scientific Research (NWO). The project aims at developing techniques to obtain improved estimates of international migration flows by country of origin and country of destination
Lung diffusing capacity for nitric oxide and carbon monoxide in relation to morphological changes as assessed by computed tomography in patients with cystic fibrosis
Background
Due to large-scale destruction, changes in membrane diffusion (Dm) may occur in cystic fibrosis (CF), in correspondence to alterations observed by computed tomography (CT). Dm can be easily quantified via the diffusing capacity for nitric oxide (DLNO), as opposed to the conventional diffusing capacity for carbon monoxide (DLCO). We thus studied the relationship between DLNO as well as DLCO and a CF-specific CT score in patients with stable CF.
Methods
Simultaneous single-breath determinations of DLNO and DLCO were performed in 21 CF patients (mean ± SD age 35 ± 9 y, FEV1 66 ± 28%pred). Patients also underwent spirometry and bodyplethysmography. CT scans were evaluated via the Brody score and rank correlations (rS) with z-scores of functional measures were computed.
Results
CT scores correlated best with DLNO (rS = -0.83; p < 0.001). Scores were also related to the volume-specific NO transfer coefficient (KNO; rS = -0.63; p < 0.01) and to DLCO (rS = -0.79; p < 0.001) but not KCO. Z-scores for DLNO were significantly lower than for DLCO (p < 0.001). Correlations with spirometric (e.g., FEV1, IVC) or bodyplethysmographic (e.g., SRaw, RV/TLC) indices were weaker than for DLNO or DLCO but most of them were also significant (p < 0.05 each).
Conclusion
In this cross sectional study in patients with CF, DLNO and DLCO reflected CT-morphological alterations of the lung better than other measures. Thus the combined diffusing capacity for NO and CO may play a future role for the non-invasive, functional assessment of structural alterations of the lung in CF
Status and Recent Results of the Acoustic Neutrino Detection Test System AMADEUS
The AMADEUS system is an integral part of the ANTARES neutrino telescope in
the Mediterranean Sea. The project aims at the investigation of techniques for
acoustic neutrino detection in the deep sea. Installed at a depth of more than
2000m, the acoustic sensors of AMADEUS are based on piezo-ceramics elements for
the broad-band recording of signals with frequencies ranging up to 125kHz.
AMADEUS was completed in May 2008 and comprises six "acoustic clusters", each
one holding six acoustic sensors that are arranged at distances of roughly 1m
from each other. The clusters are installed with inter-spacings ranging from
15m to 340m. Acoustic data are continuously acquired and processed at a
computer cluster where online filter algorithms are applied to select a
high-purity sample of neutrino-like signals. 1.6 TB of data were recorded in
2008 and 3.2 TB in 2009. In order to assess the background of neutrino-like
signals in the deep sea, the characteristics of ambient noise and transient
signals have been investigated. In this article, the AMADEUS system will be
described and recent results will be presented.Comment: 7 pages, 8 figures. Proceedings of ARENA 2010, the 4th International
Workshop on Acoustic and Radio EeV Neutrino Detection Activitie
ABO-incompatible kidney transplantation in perspective of deceased donor transplantation and induction strategies:a propensity-matched analysis
BACKGROUND: Kidney transplant candidates are blood group incompatible with roughly one out of three potential living donors. We compared outcomes after ABO-incompatible (ABOi) kidney transplantation with matched ABO-compatible (ABOc) living and deceased donor transplantation and analyzed different induction regimens. METHODS: We performed a retrospective study with propensity matching and compared patient and death-censored graft survival after ABOi versus ABOc living donor and deceased donor kidney transplantation in a nationwide registry from 2006 till 2019. RESULTS: 296 ABOi were compared to 1184 center and propensity matched ABOc living donor and 1184 deceased donor recipients (matching: recipient age, sex, blood group and PRA). Patient survival was better compared to deceased donor (hazard ratio (HR) for death of HR 0.69 [0.49-0.96], and not-significantly different from ABOc living donor recipients (HR 1.28 [0.90-1.81]). Rate of graft failure was higher compared to ABOc living donor transplantation (HR 2.63 [1.72-4.01]). Rejection occurred in 47% of 140 rituximab versus 22% of 50 rituximab/basiliximab, and 4% of 92 alemtuzumab treated recipients (p <0.001). CONCLUSIONS: ABOi kidney transplantation is superior to deceased donor transplantation. Rejection rate and graft failure are higher compared to matched ABOc living donor transplantation, underscoring the need for further studies into risk stratification and induction therapy
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