CONTRACTING BY REFERENCE TO PRICE INDICES

The commodity price index number has been defined as a figure which shows the average percentage change in the prices of a number of representative goods from one point of time to another. In the preceding article it has been argued that the use of the index number in private contracts as a method of expressing stable values is not prohibited by the gold-clause resolution of June 5, 1933; that in the decisions of the United States Supreme Court sustaining this legislation there is nothing to indicate that such contracts would run counter to the Government\u27s policies in the control of the currency; and that the commodity price index is now the only effective instrument remaining to private parties for protecting themselves against major changes in the value of money

Towards functional de novo designed proteins

Our ability to design completely de novo proteins is improving rapidly. This is true of all three main approaches to de novo protein design, which we define as: minimal, rational and computational design. Together, these have delivered a variety of protein scaffolds characterised to high resolution. This is truly impressive and a major advance from where the field was a decade or so ago. That all said, significant challenges in the field remain. Chief amongst these is the need to deliver functional de novo proteins. Such designs might include selective and/or tight binding of specified small molecules, or the catalysis of entirely new chemical transformations. We argue that, whilst progress is being made, solving such problems will require more than simply adding functional side chains to extant de novo structures. New approaches will be needed to target and build structure, stability and function simultaneously. Moreover, if we are to match the exquisite control and subtlety of natural proteins, design methods will have to incorporate multi-state modelling and dynamics. This will require more than black-box methodology, specifically increased understanding of protein conformational changes and dynamics will be needed

GPS-Geodetic Deformation Monitoring of the South-west Seismic Zone of Western Australia: Review, Description of Methodology and Results from Epoch-one

The south-west seismic zone (SWSZ) is a northwest-southeast trending belt of intraplate earthquake activity that occurs in the south-western corner of Western Australia, and is one of the most seismically active areas in Australia. Since the SWSZ lies as close as ~150 km from the ~1.4 million population of the Perth region, it poses a distinct seismic hazard. Earthquake activity recorded by Geoscience Australia over the past three decades suggests that the SWSZ could be deforming by 0.5-5 mmy-1. However, little is currently known about the magnitude and orientation of this deformation, and whether there is any associated surface expression. Previous geodetic studies of the SWSZ that used both terrestrial and Global Positioning System (GPS) techniques are inconclusive, due mainly to the imprecision of the technologies used in relation to the likely small amount of any surface deformation. Therefore, a new 48-point GPS-geodetic monitoring network has been established across the SWSZ to attempt to detect surface deformation, for which epoch-one episodic GPS-geodetic measurements were made in May 2002. This paper briefly reviews previous attempts to geodetically measure surface deformation across the SWSZ, summarises the scientific rationale for the new project, describes the network design and observations used, results of the May 2002 campaign (epoch-one) and discusses future work, including issues pertaining to the likely amount of surface deformation that can be detected

A simple method to account for thermal boundary layers during the estimation of CTmax in small ectotherms

As temperatures rise, understanding how ectotherms will become impacted by thermal stress is of critical importance. In this context, many researchers quantify critical temperatures – these are the upper (CTmax) and lower (CTmin) thermal limits at which organisms can no longer function. Most studies estimate CTs using bath-based methods where organisms are submerged within a set thermal environment. Plate-based methods (i.e. hot plates), however, offer huge opportunity for automation and are readily available in many lab settings. Plates, however, generate a unidirectional thermal boundary layer above their surface which means that the temperatures experienced by organisms of different sizes is different. This boundary layer effect can bias estimates of critical temperatures. Here, we test the hypothesis that biases in critical temperature estimation on hot plates are driven by organism height. We also quantify the composition of the boundary layer in order to correct for these biases. We assayed four differently sized species of UK ants for their CTmax in dry baths (with no boundary layer) and on hot plates (with a boundary layer). We found that hot plates overestimated the CTmax values of the different ants, and that this overestimate was larger for taller species. By statistically modelling the thickness of the thermal boundary layer, and combining with estimates of species height, we were able to correct this overestimation and eliminate methodological differences. Our study provides two main findings. First, we provide evidence that organism height is positively related to the bias present in plate-based estimates of CTmax. Second, we show that a relatively simple statistical model can correct for this bias. By using simple corrections for boundary layer effects, as we have done here, researchers could open up a new possibility space in the design and implementation of thermal tolerance assays using plates rather than restrictive dry or water baths

Redshift-weighted constraints on primordial non-Gaussianity from the clustering of the eBOSS DR14 quasars in Fourier space

We present constraints on local primordial non-Gaussianity (PNG), parametrized through $f^{\rm loc}_{\rm NL}$, using the Sloan Digital Sky Survey IV extended Baryon Oscillation Spectroscopic Survey Data Release 14 quasar sample. We measure and analyze the anisotropic clustering of the quasars in Fourier space, testing for the scale-dependent bias introduced by primordial non-Gaussianity on large scales. We derive and employ a power spectrum estimator using optimal weights that account for the redshift evolution of the PNG signal. We find constraints of $-51<f^{\rm loc}_{\rm NL}<21$ at 95% confidence level. These are amont the tightest constraints from Large Scale Structure (LSS) data. Our redshift weighting improves the error bar by 15% in comparison to the unweighted case. If quasars have lower response to PNG, the constraint degrades to $-81<f^{\rm loc}_{\rm NL}<26$, with a 40% improvement over the standard approach. We forecast that the full eBOSS dataset could reach $\sigma_{f^{\rm loc}_{\rm NL}}\simeq 5\text{-}8$ using optimal methods and full range of scales.Comment: 28 pages, 12 figures. Comments welcome

The completed SDSS-IV extended Baryon Oscillation Spectroscopic Survey: Cosmological implications from multi-tracer BAO analysis with galaxies and voids

We construct cosmic void catalogues with the DIVE void finder upon SDSS BOSS DR12 and eBOSS DR16 galaxy samples with BAO reconstruction applied, and perform a joint BAO analysis using different types of galaxies and the corresponding voids. The BAO peak is evident for the galaxy-galaxy, galaxy-void, and void-void correlation functions of all datasets, including the ones cross correlating luminous red galaxy and emission line galaxy samples. Two multi-tracer BAO fitting schemes are then tested, one combining the galaxy and void correlation functions with a weight applied to voids, and the other using a single BAO dilation parameter for all clustering measurements of different tracers. Both methods produce consistent results with mock catalogues, and on average ~10 per cent improvements of the BAO statistical uncertainties are observed for all samples, compared to the results from galaxies alone. By combining the clustering of galaxies and voids, the uncertainties of BAO measurements from the SDSS data are reduced by 5 to 15 per cent, yielding 0.9, 0.8, 1.1, 2.3, and 2.9 per cent constraints on the distance $D_{_{\rm V}}(z)$, at effective redshifts of 0.38, 0.51, 0.70, 0.77, and 0.85, respectively. When combined with BAO measurements from SDSS MGS, QSO, and Ly$\alpha$ samples, as well as the BBN results, we obtain $H_0 = 67.58 \pm 0.91\,{\rm km}\,{\rm s}^{-1}\,{\rm Mpc}^{-1}$, $\Omega_{\rm m} = 0.290 \pm 0.015$, and $\Omega_\Lambda h^2 = 0.3241 \pm 0.0079$ in the flat-$\Lambda$CDM framework, where the 1$\,\sigma$ uncertainties are around 6, 6, and 17 per cent smaller respectively, compared to constraints from the corresponding anisotropic BAO measurements without voids and LRG-ELG cross correlations.Comment: 33 pages, 30 figures, submitted to MNRA

The clustering of galaxies in the SDSS-III Baryon Oscillation Spectroscopic Survey : cosmological implications of the full shape of the clustering wedges in the data release 10 and 11 galaxy samples

We explore the cosmological implications of the angle-averaged correlation function, ξ(s), and the clustering wedges, ξ⊥(s) and ξ∥(s), of the LOWZ and CMASS galaxy samples from Data Releases 10 and 11 of the Sloan Digital Sky Survey III (SDSS-III) Baryon Oscillation Spectroscopic Survey. Our results show no significant evidence for a deviation from the standard Λ cold dark matter model. The combination of the information from our clustering measurements with recent data from the cosmic microwave background is sufficient to constrain the curvature of the Universe to Ωk = 0.0010 ± 0.0029, the total neutrino mass to ∑mν < 0.23 eV (95 per cent confidence level), the effective number of relativistic species to Neff = 3.31 ± 0.27 and the dark energy equation of state to wDE = −1.051 ± 0.076. These limits are further improved by adding information from Type Ia supernovae and baryon acoustic oscillations from other samples. In particular, this data set combination is completely consistent with a time-independent dark energy equation of state, in which case we find wDE = −1.024 ± 0.052. We explore the constraints on the growth rate of cosmic structures assuming f(z) = Ωm(z)γ and obtain γ = 0.69 ± 0.15, consistent with the predictions of general relativity of γ = 0.55.Publisher PDFPeer reviewe

Applications of advanced metrology for understanding the effects of drying temperature in the lithium-ion battery electrode manufacturing process

The performance of lithium-ion batteries is determined by the architecture and properties of electrodes formed during manufacturing, particularly in the drying process when solvent is removed and the electrode structure is formed. Temperature is one of the most dominant parameters that influences the process, and therefore a comparison of temperature effects on both NMC622-based cathodes (PVDF-based binder) and graphite-based anodes (water-based binder) dried at RT, 60, 80, 100 and 120 °C has been undertaken. X-ray computed tomography showed that NMC622 particles concentrated at the surface of the cathode coating except when dried at 60 °C. However, anodes showed similar graphite distributions at all temperatures. The discharge capacities for the cathodes dried at 60, 80, 100 and 120 °C displayed the following trend: 60 °C < 80 °C < 100 °C < 120 °C as C-rate was increased which was consistent with the trends found in adhesion testing between 60 and 120 °C. Focused-ion beam scanning electrode microscopy and energy-dispersive X-ray spectroscopy suggested that the F-rich binder distribution was largely insensitive to temperature for cathodes. In contrast, conductivity enhancing fine carbon agglomerated on the upper surface of the active NMC particles in the cathode as temperature increased. The cathode dried at RT had the highest adhesion force of 0.015 N mm−1 and the best electrochemical rate performance. Conversely, drying temperature had no significant effect on the electrochemical performance of the anode, which was consistent with only a relatively small change in the adhesion, related to the use of lower adhesion water-based binders