558 research outputs found
Ethnic concentration and language fluency of immigrants in Germany
Studies that investigate the effect of the regional ethnic composition on immigrant outcomes have been complicated by the self-selection of ethnic minorities into specific neighbourhoods. We analyse the impact of own-ethnic concentration on the language proficiency of immigrants by exploiting the fact that the initial placement of guest-workers after WWII was determined by labour demanding firms and the federal labour administration and hence exogenous to immigrant workers. Combining several data sets, we find a small but robust and significant negative effect of ethnic concentration on immigrantsâ language ability. Simulation results of a choice model in which location and learning decisions are taken simultaneously confirm the presence of the effect. Immigrants with high learning costs are inclined to move to ethnic enclaves, so that the share of German-speakers would increase only modestly even under the counterfactual scenario of a regionally equal distribution of immigrants across Germany
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Do Ethnic Enclaves Impede Immigrantsâ Integration? Evidence from a Quasi-Experimental Social-Interaction Approach
It is widely debated whether immigrants who live among co-ethnics are less willing to integrate into the host society. Exploiting the quasi-experimental guest worker placement across German regions during the 1960/70s as well as information on immigrants' inter-ethnic contact networks and social activities, we are able to identify the causal effect of ethnic concentration on social integration. The exogenous placement of immigrants âswitches offâ observable and unobservable differences in the willingness or ability to integrate which have confounded previous studies. Evidence suggests that the presence of co-ethnics increases migrants' interaction cost with natives and thus reduces the likelihood of integration
Acute Sets of Exponentially Optimal Size
We present a simple construction of an acute set of size (Formula presented.) in (Formula presented.) for any dimension d. That is, we explicitly give (Formula presented.) points in the d-dimensional Euclidean space with the property that any three points form an acute triangle. It is known that the maximal number of such points is less than (Formula presented.). Our result significantly improves upon a recent construction, due to Dmitriy Zakharov, with size of order (Formula presented.) where (Formula presented.) is the golden ratio. © 2018 Springer Science+Business Media, LLC, part of Springer Natur
Regular Incidence Complexes, Polytopes, and C-Groups
Regular incidence complexes are combinatorial incidence structures
generalizing regular convex polytopes, regular complex polytopes, various types
of incidence geometries, and many other highly symmetric objects. The special
case of abstract regular polytopes has been well-studied. The paper describes
the combinatorial structure of a regular incidence complex in terms of a system
of distinguished generating subgroups of its automorphism group or a
flag-transitive subgroup. Then the groups admitting a flag-transitive action on
an incidence complex are characterized as generalized string C-groups. Further,
extensions of regular incidence complexes are studied, and certain incidence
complexes particularly close to abstract polytopes, called abstract polytope
complexes, are investigated.Comment: 24 pages; to appear in "Discrete Geometry and Symmetry", M. Conder,
A. Deza, and A. Ivic Weiss (eds), Springe
Hadron Spectroscopy with Dynamical Chirally Improved Fermions
We simulate two dynamical, mass degenerate light quarks on 16^3x32 lattices
with a spatial extent of 2.4 fm using the Chirally Improved Dirac operator. The
simulation method, the implementation of the action and signals of
equilibration are discussed in detail. Based on the eigenvalues of the Dirac
operator we discuss some qualitative features of our approach. Results for
ground state masses of pseudoscalar and vector mesons as well as for the
nucleon and delta baryons are presented.Comment: 26 pages, 17 figures, 10 table
The Fermat-Torricelli problem in normed planes and spaces
We investigate the Fermat-Torricelli problem in d-dimensional real normed
spaces or Minkowski spaces, mainly for d=2. Our approach is to study the
Fermat-Torricelli locus in a geometric way. We present many new results, as
well as give an exposition of known results that are scattered in various
sources, with proofs for some of them. Together, these results can be
considered to be a minitheory of the Fermat-Torricelli problem in Minkowski
spaces and especially in Minkowski planes. This demonstrates that substantial
results about locational problems valid for all norms can be found using a
geometric approach
The sign problem across the QCD phase transition
The average phase factor of the QCD fermion determinant signals the strength
of the QCD sign problem. We compute the average phase factor as a function of
temperature and baryon chemical potential using a two-flavor NJL model. This
allows us to study the strength of the sign problem at and above the chiral
transition. It is discussed how the anomaly affects the sign problem.
Finally, we study the interplay between the sign problem and the endpoint of
the chiral transition.Comment: 9 pages and 9 fig
Synthesis, structural characterization, antimicrobial and cytotoxic effects of aziridine, 2-aminoethylaziridine and azirine complexes of copper(II) and palladium(II).
The synthesis, spectroscopic and X-ray structural characterization of copper(II) and palladium(II) complexes with aziridine ligands as 2-dimethylaziridine HNCH2CMe2 (a), the bidentate N-(2-aminoethyl)aziridines C2H4NC2H4NH2 (b) or CH2CMe2NCH2CMe2NH2 (c) as well as the unsaturated azirine NCH2CPh (d) are reported. Cleavage of the cyclometallated Pd(II) dimer [ÎŒ-Cl(C6H4CHMeNMe2-C,N)Pd]2 with ligand a yielded compound [Cl(NHCH2CMe2)(C6H4CHMe2NMe2-C,N)Pd] (1a). The reaction of the aziridine complex trans-[Cl2Pd(HNC2H4)2] with an excess of aziridine in the presence of AgOTf gave the ionic chelate complex trans-[(C2H4NC2H4NH2-N,NâČ)2Pd](OTf)2 (2b) which contains the new ligand b formed by an unexpected insertion and ring opening reaction of two aziridines (âaziridine dimerizationâ). CuCl2 reacted in pure HNC2H4 or HNCH2CMe2 (b) again by âdimerizationâ to give the tris-chelated ionic complex [Cu(C2H4NC2H4NH2-N,NâČ)3]Cl2 (3b) or the bis-chelated complex [CuCl(C2H2Me2NC2H2Me2NH2-N,NâČ)2]Cl (4c). By addition of 2H-3-phenylazirine (d) to PdCl2, trans-[Cl2Pd(NCH2CPh)2] (5d) was formed. All new compounds were characterized by NMR, IR and mass spectra and also by X-ray structure analyses (except 3b). Additionally the cytotoxic effects of these complexes were examined on HL-60 and NALM-6 human leukemia cells and melanoma WM-115 cells. The antimicrobial activity was also determined. The growth of Gram-positive bacterial strains (S. aureus, S. epidermidis, E. faecalis) was inhibited by almost all tested complexes at the concentrations of 37.5â300.0 ÎŒg mLâ1. However, MIC values of complexes obtained for Gram-negative E. coli and P. aeruginosa, as well as for C. albicans yeast, mostly exceeded 300 ÎŒg mLâ1. The highest antibacterial activity was achieved by complexes 1a and 2b. Complex 2b also inhibited the growth of Gram-negative bacteria.
Graphical abstract: Synthesis, structural characterization, antimicrobial and cytotoxic effects of aziridine, 2-aminoethylaziridine and azirine complexes of copper(ii) and palladium(ii
Improving statistical inference on pathogen densities estimated by quantitative molecular methods: malaria gametocytaemia as a case study
BACKGROUND: Quantitative molecular methods (QMMs) such as quantitative real-time polymerase chain reaction (q-PCR), reverse-transcriptase PCR (qRT-PCR) and quantitative nucleic acid sequence-based amplification (QT-NASBA) are increasingly used to estimate pathogen density in a variety of clinical and epidemiological contexts. These methods are often classified as semi-quantitative, yet estimates of reliability or sensitivity are seldom reported. Here, a statistical framework is developed for assessing the reliability (uncertainty) of pathogen densities estimated using QMMs and the associated diagnostic sensitivity. The method is illustrated with quantification of Plasmodium falciparum gametocytaemia by QT-NASBA. RESULTS: The reliability of pathogen (e.g. gametocyte) densities, and the accompanying diagnostic sensitivity, estimated by two contrasting statistical calibration techniques, are compared; a traditional method and a mixed model Bayesian approach. The latter accounts for statistical dependence of QMM assays run under identical laboratory protocols and permits structural modelling of experimental measurements, allowing precision to vary with pathogen density. Traditional calibration cannot account for inter-assay variability arising from imperfect QMMs and generates estimates of pathogen density that have poor reliability, are variable among assays and inaccurately reflect diagnostic sensitivity. The Bayesian mixed model approach assimilates information from replica QMM assays, improving reliability and inter-assay homogeneity, providing an accurate appraisal of quantitative and diagnostic performance. CONCLUSIONS: Bayesian mixed model statistical calibration supersedes traditional techniques in the context of QMM-derived estimates of pathogen density, offering the potential to improve substantially the depth and quality of clinical and epidemiological inference for a wide variety of pathogens
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