Oral myiasis in mentally challenged patient: a case report

Myiasis is the infestation of live human and vertebrate animal with Dipterous larvae which feed on host’s dead or living tissue. This condition is a result of neglected approach towards oral hygiene along with mental and physical challenges of patient. A case of oral myiasis in the maxillary anterior region in an 18 years old female with neurologic defi-cit caused by the larvae (maggots) is reported. The management consists of manual removal of larvae by topical application of turpentine oil, oral therapy with Ivermectin and surgical debridement of oral wound

Design, Synthesis, and Biological Evaluation of Coumarin-Triazole Hybrid Molecules as Potential Antitumor and Pancreatic Lipase Agents

WOS: 000406714000001PubMed: 28543820The design, synthesis, and investigation of antitumor and anti-lipase activities of some coumarin-triazole hybrid molecules are reported. the synthesis of these hybrid molecules was performed under microwave irradiation and conventional heating procedures. the newly synthesized hybrid molecules were investigated as inhibitors against four tumor cell lines (BT20 human breast carcinoma, SK-Mel 128 melanoma, DU-145 prostate carcinoma, and A549 lung carcinoma) and porcine pancreatic lipase (PPL). Most of these compounds showed notable antitumor activities against the tested tumor cell lines, and compounds 8i and 8l showed the best anti-lipase activity of 99.30 +/- 0.56% and 99.85 +/- 1.21%, respectively, at a concentration of 10 mu M.Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [115Z047]; TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK)This work was supported by the Scientific and Technological Research Council of Turkey (TUBITAK) under the project number of 115Z047. Authors thank to TUBITAK for this support

Treatment For The Large Aggressive Benign Lesions Of The Jaws

Our aim was to evaluate the clinical outcome of the conservative management of the significantly large benign aggressive lesions of the jaws