893 research outputs found

    Global implications of Trump’s fiscal stimulus

    Get PDF
    Recent commentary on the presidential election has touched on the domestic appeal of Trump’s protectionist, “America first” economic policy. LSE Visiting Fellow Guillermo Felices reflects on the broader implications of this protectionist stance, and argues that an international backlash could undermine the sustainability of this economic position. He also notes that though the anti-establishment sentiment seen in the UK and US may reappear in European elections this coming year, their capacity to pursue a similarly radical policy shift is limited

    Taula rodona. Present i futur d'un Baix Vallès saludable

    Get PDF

    The Role of TEC Family Kinases in Innate T Cell Development and Function: a Dissertation

    Get PDF
    The Tec family kinases Itk and Rlk have been previously shown to have an important role in signaling downstream of the T cell receptor [TCR]. Almost all of the work done in the past on these two kinases looked at their role in conventional αβ T cells, specifically CD4+ T cells. These studies demonstrated functions for Itk [primarily] and Rlk in T cell development, activation, and differentiation. However, despite the wealth of knowledge on conventional CD4+ T cells, prior to the work presented here little to no studies addressed the role of Tec family kinases on CD8+ or innate T cell development. My studies show a clear role for Itk [and in some cases Rlk] in innate T cell development; whether it be deprecating, in the case of innate CD8+ T cells or some subsets of γδ T cells, or beneficial, in the case of NKT cells. I show that Itk has a crucial role in conventional CD8+ T cell development, as absence of Itk [or Itk and Rlk] causes strongly reduced numbers of conventional CD8+ T cells and a vigorous enhancement of an innate-like CD8+ T cell population. In NKT cells, my work demonstrates that Itk [and to a lesser extent Rlk] is required for terminal maturation, survival, and cytokine secretion. Finally, on γδ T cells Itk is important in maintaining the Th1 cytokine secretion profile usually associated with these cells, and regulating the development of CD4+ or NK1.1+ γδ T cells. Taken together, this work clearly illustrates an important role for Tec family kinases in innate T cell development and function

    Book Review

    Get PDF
    Obra ressenyada: Leocadio MARTÍN MINGORANCE, El modelo lexemáticofuncional. Granada: Editorial Universidad de Granada, 1998

    Paratextualidad y novela: las partes del texto o el "diseño editorial"

    Get PDF
    Este artículo es un estudio acerca de aquellas formas constitutivas externas –parte, capítulo, párrafo, título, etc.- en el que el texto de una narración aparece distribuido en las páginas de un libro. Además, y en especial, se analiza su estructura paratextual y el funcionamiento de las mismas como claves identificadora, descriptiva y apelativa textuales. Esto es, todo su dispositivo autoral y pragmático que viene a convertirse en una de las razones de ser del texto novelesco.This article provides a study of the external constitutive parts –division, chapter, paragraph, title…- in which narrations are typically divided in books. Furthermore, in also analyses paratextual structure and how the parts of a text serve as identifying, descriptive and appellative textual keys. Thus, the authorial and pragmatic disposition of text parts will be shown as one of the essential characteristics of the novel as a text

    El campo semántico de los sustantivos que expresan maldad conductual en la lengua inglesa

    Get PDF
    A lo largo de las líneas siguientes sólo hemos pretendido desarrollar prácticamente presupuestos y fórmulas teóricas esbozadas por algunas de las figuras más relevantes de la moderna semántica estructural. Para ello, hemos confeccionado un campo semántico representativo de los sustantivos que expresan la maldad conductual en la lengua inglesa. La aportación de este trabajo podría definirse como la contrastación práctica de las grandes ventajas que nos ofrece esta línea metodológica para resolver algunos de los intrincados problemas en un estudio científico del significado. El aspecto más complejo de este estudio ha consistido en hallar las precisiones y matizaciones necesarias para diferenciar entre sí los lexemas en base a las dimensiones, subdimensiones, subgrupos, semas y clasemas correspondientes y, de este modo, proceder a la gestación de nuestro campo

    Paratextualidad y novela: las partes del texto o el "diseño editorial"

    Get PDF
    Este artículo es un estudio acerca de aquellas formas constitutivas externas —parte, capítulo, párrafo, título, etc.— en el que el texto de una narración aparece distribuido en las páginas de un libro. Además, y en especial, se analiza su estructura paratextual (el texto como mercancía), y el funcionamiento de las mismas como claves identificadora, descriptiva y apelativa textuales. Esto es, todo su dispositivo autoral y pragmático que viene a convertirse en una de las razones de ser del texto novelesco (Genette 1987).This article provides a study of the external constitutive parts —division, chapter, paragraph, title…— in which narrations are typically divided in books. Furthermore, it also analyses paratextual structure (the text as merchandise) and how the parts of a text serve as identifying, descriptive and appellative textual keys. Thus, the authorial and pragmatic disposition of text parts will be shown as one of the essential characteristics of the novel as a text (Genette 1987).peerReviewe

    The process of constructing ontological meaning based on criminal law verbs

    Get PDF
    This study intends to account for the process involved in the construction of the conceptual meaning of verbs (#EVENTS) directly related to legal aspects of terrorism and organized crime based on the evidence provided by the Globalcrimeterm Corpus and the consistent application of specific criteria for term extraction. The selected 49 concepts have eventually been integrated in the Core Ontology of FunGramKB (Functional Grammar Knowledge Base), a knowledge base which is founded on the principles of deep semantics and is also aimed at the computational development of the Lexical Constructional Model (www.fungramkb.com). To achieve this purpose, key phases of the COHERENT methodology (Periñán Pascual & Mairal Usón 2011) are followed, particularly those which involve the modelling, subsumption and hierarchisation of the aforementioned verbal concepts. The final outcome of this research shows that most of the apparently specialised conceptual units should eventually be included in the Core Ontology instead of the specific Globalcrimeterm Subontology, due to the fact that the semantic content of their corresponding lexical units can be found in widely used learner`s dictionaries and, consequently, this conceptual information is not only shared by the experts in the field but also by the layperson and the average speaker of the language

    El campo semántico de los adjetivos que expresan maldad conductual en la lengua inglesa

    Get PDF
    corecore