The inviscid compressible Goertler problem

The growth rate is studied of Goertler vortices in a compressible flow in the inviscid limit of large Goertler number. Numerical solutions are obtained for 0(1) wavenumbers. The further limits of large Mach number and large wavenumber with 0(1) Mach number are considered. It is shown that two different types of disturbance modes can appear in this problem. The first is a wall layer mode, so named as it has its eigenfunctions trapped in a thin layer away from the wall and termed a trapped layer mode for large wavenumbers and an adjustment layer mode for large Mach numbers, since then this mode has its eigenfunctions concentrated in the temperature adjustment layer. The near crossing of the modes which occurs in each of the limits mentioned is investigated

Wavenumber selection for small-wavelength Goertler vortices in curved channel flows

The problem of wavenumber selection for fully nonlinear, small-wavelength Goertler vortices in a curved channel flow is considered. These types of Goertler vortices were first considered by Hall & Lakin (1988) for an external boundary layer flow. They proved particularly amenable to asymptotic description, it was possible to consider vortices large enough so that the mean flow correction driven by them is as large as the basic state, and this prompted the authors to consider them in a curved channel flow as an initial application of the phase-equation approach to Goertler vortices. This involves the assumption that the phase variable of these Goertler vortices varies on slow spanwise and time scales, then an analysis of both inside and outside the core region, to which vortex activity is restricted, leads to a system of partial differential equations which can be solved numerically for the wavenumber. The authors consider in particular the effect on the wavenumber of the outer channel wall varying on the same slow spanwise scale as the phase variable

The nonlinear evolution of modes on unstable stratified shear layers

The nonlinear development of disturbances in stratified shear flows (having a local Richardson number of value less than one quarter) is considered. Such modes are initially fast growing but, like related studies, we assume that the viscous, non-parallel spreading of the shear layer results in them evolving in a linear fashion until they reach a position where their amplitudes are large enough and their growth rates have diminished sufficiently so that amplitude equations can be derived using weakly nonlinear and non-equilibrium critical-layer theories. Four different basic integro-differential amplitude equations are possible, including one due to a novel mechanism; the relevant choice of amplitude equation, at a particular instance, being dependent on the relative sizes of the disturbance amplitude, the growth rate of the disturbance, its wavenumber, and the viscosity of the fluid. This richness of choice of possible nonlinearities arises mathematically from the indicial Frobenius roots of the governing linear inviscid equation (the Taylor-Goldstein equation) not, in general, differing by an integer. The initial nonlinear evolution of a mode will be governed by an integro-differential amplitude equations with a cubic nonlinearity but the resulting significant increase in the size of the disturbance's amplitude leads on to the next stage of the evolution process where the evolution of the mode is governed by an integro-differential amplitude equations with a quintic nonlinearity. Continued growth of the disturbance amplitude is expected during this stage, resulting in the effects of nonlinearity spreading to outside the critical level, by which time the flow has become fully nonlinear

The nonlinear evolution of inviscid Goertler vortices in three-dimensional boundary layers

The nonlinear development of inviscid Gortler vortices in a three-dimensional boundary layer is considered. We do not follow the classical approach of weakly nonlinear stability problems and consider a mode which has just become unstable. Instead we extend the method of Blackaby, Dando, and Hall (1992), which considered the closely related nonlinear development of disturbances in stratified shear flows. The Gortler modes we consider are initially fast growing and we assume, following others, that boundary-layer spreading results in them evolving in a linear fashion until they reach a stage where their amplitudes are large enough and their growth rates have diminished sufficiently so that amplitude equations can be derived using weakly nonlinear and non-equilibrium critical-layer theories. From the work of Blackaby, Dando and Hall (1993) is apparent, given the range of parameters for the Gortler problem, that there are three possible nonlinear integro-differential evolution equations for the disturbance amplitude. These are a cubic due to viscous effects, a cubic which corresponds to the novel mechanism investigated in this previous paper, and a quintic. In this paper we shall concentrate on the two cubic integro-differential equations and in particular, on the one due to the novel mechanism as this will be the first to affect a disturbance. It is found that the consideration of a spatial evolution problem as opposed to temporal (as was considered in Blackaby, Dando, and Hall, 1992) causes a number of significant changes to the evolution equations

Mars Phobos and Deimos Survey (M-PADS) – A Martian Moons Orbiter and Phobos Lander

We describe a Mars 'Micro Mission' for detailed study of the martian satellites Phobos and Deimos. The mission involves two ~330 kg spacecraft equipped with solar electric propulsion to reach Mars orbit. The two spacecraft are stacked for launch: an orbiter for remote investigation of the moons and in situ studies of their environment in Mars orbit, and another carrying a lander for in situ measurements on the surface of Phobos (or alternatively Deimos). Phobos and Deimos remain only partially studied, and Deimos less well than Phobos. Mars has almost always been the primary mission objective, while the more dedicated Phobos project (1988-89) failed to realise its full potential. Many questions remain concerning the moons' origins, evolution, physical nature and composition. Current missions, such as Mars Express, are extending our knowledge of Phobos in some areas but largely neglect Deimos. The objectives of M-PADS focus on: origins and evolution, interactions with Mars, volatiles and interiors, surface features, and differences. The consequent measurement requirements imply both landed and remote sensing payloads. M-PADS is expected to accommodate a 60 kg orbital payload and a 16 kg lander payload. M-PADS resulted from a BNSC-funded study carried out in 2003 to define candidate Mars Micro Mission concepts for ESA's Aurora programme

Comparative Composition, Diversity and Trophic Ecology of Sediment Macrofauna at Vents, Seeps and Organic Falls

Sediments associated with hydrothermal venting, methane seepage and large organic falls such as whale, wood and plant detritus create deep-sea networks of soft-sediment habitats fueled, at least in part, by the oxidation of reduced chemicals. Biological studies at deep-sea vents, seeps and organic falls have looked at macrofaunal taxa, but there has yet to be a systematic comparison of the community-level attributes of sediment macrobenthos in various reducing ecosystems. Here we review key similarities and differences in the sediment-dwelling assemblages of each system with the goals of (1) generating a predictive framework for the exploration and study of newly identified reducing habitats, and (2) identifying taxa and communities that overlap across ecosystems. We show that deep-sea seep, vent and organic-fall sediments are highly heterogeneous. They sustain different geochemical and microbial processes that are reflected in a complex mosaic of habitats inhabited by a mixture of specialist (heterotrophic and symbiont-associated) and background fauna. Community-level comparisons reveal that vent, seep and organic-fall macrofauna are very distinct in terms of composition at the family level, although they share many dominant taxa among these highly sulphidic habitats. Stress gradients are good predictors of macrofaunal diversity at some sites, but habitat heterogeneity and facilitation often modify community structure. The biogeochemical differences across ecosystems and within habitats result in wide differences in organic utilization (i.e., food sources) and in the prevalence of chemosynthesis-derived nutrition. In the Pacific, vents, seeps and organic-falls exhibit distinct macrofaunal assemblages at broad-scales contributing to ß diversity. This has important implications for the conservation of reducing ecosystems, which face growing threats from human activities

Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte–myelin dysfunction

Although the underlying neurobiology of major mental illness (MMI) remains unknown, emerging evidence implicates a role for oligodendrocyte–myelin abnormalities. Here, we took advantage of a large family carrying a balanced t(1;11) translocation, which substantially increases risk of MMI, to undertake both diffusion tensor imaging and cellular studies to evaluate the consequences of the t(1;11) translocation on white matter structural integrity and oligodendrocyte–myelin biology. This translocation disrupts among others the DISC1 gene which plays a crucial role in brain development. We show that translocation-carrying patients display significant disruption of white matter integrity compared with familial controls. At a cellular level, we observe dysregulation of key pathways controlling oligodendrocyte development and morphogenesis in induced pluripotent stem cell (iPSC) derived case oligodendrocytes. This is associated with reduced proliferation and a stunted morphology in vitro. Further, myelin internodes in a humanized mouse model that recapitulates the human translocation as well as after transplantation of t(1;11) oligodendrocyte progenitors were significantly reduced when compared with controls. Thus we provide evidence that the t(1;11) translocation has biological effects at both the systems and cellular level that together suggest oligodendrocyte–myelin dysfunction

A História da Alimentação: balizas historiográficas

Os M. pretenderam traçar um quadro da História da Alimentação, não como um novo ramo epistemológico da disciplina, mas como um campo em desenvolvimento de práticas e atividades especializadas, incluindo pesquisa, formação, publicações, associações, encontros acadêmicos, etc. Um breve relato das condições em que tal campo se assentou faz-se preceder de um panorama dos estudos de alimentação e temas correia tos, em geral, segundo cinco abardagens Ia biológica, a econômica, a social, a cultural e a filosófica!, assim como da identificação das contribuições mais relevantes da Antropologia, Arqueologia, Sociologia e Geografia. A fim de comentar a multiforme e volumosa bibliografia histórica, foi ela organizada segundo critérios morfológicos. A seguir, alguns tópicos importantes mereceram tratamento à parte: a fome, o alimento e o domínio religioso, as descobertas européias e a difusão mundial de alimentos, gosto e gastronomia. O artigo se encerra com um rápido balanço crítico da historiografia brasileira sobre o tema