42 research outputs found
Novel β-cyclodextrin–eosin conjugates
- Author
- Publication venue
- 'Beilstein Institut'
- Publication date
- 01/01/2017
- Field of study
Eosin B (EoB) and eosin Y (EoY), two xanthene dye derivatives with photosensitizing ability were prepared in high purity through an improved synthetic route. The dyes were grafted to a 6-monoamino-β-cyclodextrin scaffold under mild reaction conditions through a stable amide linkage using the coupling agent 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride. The molecular conjugates, well soluble in aqueous medium, were extensively characterized by 1D and 2D NMR spectroscopy and mass spectrometry. Preliminary spectroscopic investigations showed that the β-cyclodextrin–EoY conjugate retains both the fluorescence properties and the capability to photogenerate singlet oxygen of the unbound chromophore. In contrast, the corresponding β-cyclodextrin–EoB conjugate did not show either relevant emission or photosensitizing activity probably due to aggregation in aqueous medium, which precludes any response to light excitation
A multifunctional β-cyclodextrin-conjugate photodelivering nitric oxide with fluorescence reporting
- Author
- András Darcsi
- Bortolus
- Caruso
- Coneski
- Damien Afonso
- Davis
- Ford
- Ford
- Fraix
- Fry
- Gábor Benkovics
- Hasan
- Ignarro
- Ignarro
- Jia
- Jicsinszky
- Kirejev
- Loftsson
- Marta Perez-Lloret
- Matsui
- Mazzaglia
- Mazzaglia
- Milo Malanga
- Monti
- Mourtzis
- Mourtzis
- Pellois
- Piras
- Riccio
- Salvatore Sortino
- Seabra
- Sortino
- Szabolcs Béni
- Ueno
- Veldhuyzen
- Vittorino
- Wang
- Wang
- Weinstain
- Wilkinson
- Yannakopoulou
- Éva Fenyvesi
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study
The Science Case for Multi-Object Spectroscopy on the European ELT
- Author
- Afonso Jose
- Almaini Omar
- Amram Philippe
- Aussel Hervé
- Barbuy Beatriz
- Basden Alistair
- Bastian Nate
- Battaglia Giuseppina
- Biller Beth
- Bonifacio Piercarlo
- Bouché Nicholas
- Bunker Andy
- Caffau Elisabetta
- Charlot Stephane
- Cirasuolo Michele
- Clenet Yann
- Combes Francoise
- Conselice Chris
- Contini Thierry
- Cuby Jean-Gabriel
- Dalton Gavin
- Davies Ben
- de Koter Alex
- Disseau Karen
- Dunlop Jim
- Epinat Benoît
- Evans Chris
- Feltzing Sofia
- Ferguson Annette
- Fiore Fabrizio
- Flores Hector
- Fontana Adriano
- Fusco Thierry
- Gadotti Dimitri
- Gallazzi Anna
- Gallego Jesus
- Giallongo Emanuele
- Gonçalves Thiago
- Gratadour Damien
- Guenther Eike
- Hammer Francois
- Hill Vanessa
- Huertas-Company Marc
- Ibata Roridgo
- Kaper Lex
- Korn Andreas
- Larsen Søren
- Le Fèvre Olivier
- Lemasle Bertrand
- Maraston Claudia
- Mei Simona
- Mellier Yannick
- Morris Simon
- Paumard Thibaut
- Pello Roser
- Pentericci Laura
- Peroux Celine
- Petitjean Patrick
- Puech Mathieu
- Rodrigues Myriam
- Rodríguez-Muñoz Lucía
- Rouan Daniel
- Sana Hugues
- Schaerer Daniel
- Telles Eduardo
- Trager Scott
- Tresse Laurence
- Welikala Niraj
- Zibetti Stefano
- Ziegler Bodo
- Östlin Göran
- Publication venue
- Publication date
- 01/01/2015
- Field of study
This White Paper presents the scientific motivations for a multi-object
spectrograph (MOS) on the European Extremely Large Telescope (E-ELT). The MOS
case draws on all fields of contemporary astronomy, from extra-solar planets,
to the study of the halo of the Milky Way and its satellites, and from resolved
stellar populations in nearby galaxies out to observations of the earliest
'first-light' structures in the partially-reionised Universe. The material
presented here results from thorough discussions within the community over the
past four years, building on the past competitive studies to agree a common
strategy toward realising a MOS capability on the E-ELT. The cases have been
distilled to a set of common requirements which will be used to define the
MOSAIC instrument, entailing two observational modes ('high multiplex' and
'high definition'). When combined with the unprecedented sensitivity of the
E-ELT, MOSAIC will be the world's leading MOS facility. In analysing the
requirements we also identify a high-multiplex MOS for the longer-term plans
for the E-ELT, with an even greater multiplex (>1000 targets) to enable studies
of large-scale structures in the high-redshift Universe. Following the green
light for the construction of the E-ELT the MOS community, structured through
the MOSAIC consortium, is eager to realise a MOS on the E-ELT as soon as
possible. We argue that several of the most compelling cases for ELT science,
in highly competitive areas of modern astronomy, demand such a capability. For
example, MOS observations in the early stages of E-ELT operations will be
essential for follow-up of sources identified by the James Webb Space Telescope
(JWST). In particular, multi-object adaptive optics and accurate sky
subtraction with fibres have both recently been demonstrated on sky, making
fast-track development of MOSAIC feasible.Comment: Significantly expanded and updated version of previous ELT-MOS White
Paper, so there is some textual overlap with arXiv:1303.002
Recommended from our members
Climate seasonality limits leaf carbon assimilation and wood productivity in tropical forests
- Author
- Anderson Liana O.
- Aragão Luiz E. O. C.
- Baker Timothy R.
- Becker Gabriel Sebastian
- Beeckman Hans
- Boanerges Souza Danilo
- Bonal Damien
- Botosso Paulo Cesar
- Bowman David M. J. S.
- Brede Benjamin
- Brown Foster Irving
- Bräuning Achim
- Camarero Jesus Julio
- Camargo Plínio Barbosa
- Cardoso Fernanda C. G.
- Carvalho Fabrício Alvim
- Castro Wendeson
- Chagas Rubens Koloski
- Chave Jérome
- Chidumayo Emmanuel N.
- Clark Deborah A.
- Costa Flavia Regina Capellotto
- Couralet Camille
- da Silva Mauricio Paulo Henrique
- Dalitz Helmut
- de Castro Vinicius Resende
- de Freitas Milani Jaçanan Eloisa
- de Oliveira Edilson Consuelo
- de Souza Arruda Luciano
- Devineau Jean-Louis
- Drew David M.
- Durigan Giselda
- Dünisch Oliver
- Elifuraha Elisha
- Fedele Marcio
- Ferreira Fedele Ligia
- Figueiredo Filho Afonso
- Finger César Augusto Guimarães
- Franco Augusto César
- Freitas Júnior João Lima
- Galvão Franklin
- Gebrekirstos Aster
- Gliniars Robert
- Graça Paulo Maurício Lima de Alencastro
- Griffiths Anthony D.
- Grogan James
- Guan Kaiyu
- Homeier Jürgen
- Hérault Bruno
- Kanieski Maria Raquel
- Kho Lip Khoon
- Koenig Jennifer
- Kohler Sintia Valerio
- Krepkowski Julia
- Lemos-Filho José Pires
- Lieberman Diana
- Lieberman Milton Eugene
- Lisi Claudio Sergio
- Longhi Santos Tomaz
- López Ayala José Luis
- Maeda Eduardo Eijji
- Malhi Yadvinder
- Maria Vivian R. B.
- Marques Marcia C. M.
- Marques Renato
- Maza Chamba Hector
- Mbwambo Lawrence
- Melgaço Karina Liana Lisboa
- Mendivelso Hooz Angela
- Murphy Brett P.
- O'Brien Joseph J.
- Oberbauer Steven F.
- Okada Naoki
- Prior Lynda D.
- Pélissier Raphaël
- Roig Fidel Alejandro
- Ross Michael
- Rossatto Davi Rodrigo
- Rossi Vivien
- Rowland Lucy
- Rutishauser Ervan
- Santana Hellen
- Schulze Mark
- Selhorst Diogo
- Silva Williamar Rodrigues
- Silveira Marcos
- Spannl Susanne
- Stahl Clément
- Swaine Michael D.
- Toledo José Julio
- Toledo Marcos Miranda
- Toledo Marisol
- Toma Takeshi
- Tomazello Filho Mario
- Valdez Hernández Juan Ignacio
- Verbesselt Jan
- Vieira Simone Aparecida
- Vincent Grégoire
- Volkmer de Castilho Carolina
- Volland Franziska
- Wagner Fabien H.
- Worbes Martin
- Zanon Magda Lea Bolzan
- Publication venue
- Copernicus Publications
- Publication date
- Field of study
The seasonal climate drivers of the carbon cycle in tropical forests remain poorly known, although these forests account for more carbon assimilation and storage than any other terrestrial ecosystem. Based on a unique combination of seasonal pan-tropical data sets from 89 experimental sites (68 include aboveground wood productivity measurements and 35 litter productivity measurements), their associated canopy photosynthetic capacity (enhanced vegetation index, EVI) and climate, we ask how carbon assimilation and aboveground allocation are related to climate seasonality in tropical forests and how they interact in the seasonal carbon cycle. We found that canopy photosynthetic capacity seasonality responds positively to precipitation when rainfall is < 2000 mm yr⁻¹ (water-limited forests) and to radiation otherwise (light-limited forests). On the other hand, independent of climate limitations, wood productivity and litterfall are driven by seasonal variation in precipitation and evapotranspiration, respectively. Consequently, light-limited forests present an asynchronism between canopy photosynthetic capacity and wood productivity. First-order control by precipitation likely indicates a decrease in tropical forest productivity in a drier climate in water-limited forest, and in current light-limited forest with future rainfall < 2000 mm yr⁻¹
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Aaron Joffe
- Aaron Mark Hernandez
- Aaron Mark Hernandez
- Abby Lewis
- Abdelhamid Hachimi
- Abdualhamid I Alshrif
- Abel Viveiros
- Abhijit Duggal
- Abidin Oner Balbay
- Achilleas Chovas
- Ade Susanti
- Adi Hadzibegovic
- Adonis Dungca
- Adrian Belii
- Adrian Belii
- Adriana Onelli
- Afolabi Owojuyigbe
- Agnieszka Kubisz-Pudelko
- Agnès Blanc
- Ahmed Ali Aboufray
- Ahmed Elhadi
- Ahmed Ramadan Triki
- Ahmed Subhy Alsheikhly
- Ahmed Zaki
- Ahmet Eroglu
- Aidan O'Shea
- Aikaterini Dimoula
- Aikaterini Efthimiou
- Aikaterini Flevari
- Ailesh Corcoran
- AiPing Bi
- Aiua Ren
- Aizhi Zhang
- Ajitha Rajendran
- Akemi Hirao
- Akira Ohuchi
- Aktham Yaghi
- Ala Khaled
- Alan Sustic
- Alan Sustic
- Alba Riera
- Alban Greca
- Alberto de Jesús Ortiz
- Alberto Peratoner
- Alejandra Aucapina
- Alejandra Azahara Marguello Fernandez
- Alejandro Ibarra
- Aleksandar Šuput
- Aleksandra Gutysz-Wojnicka
- Alessandra Negro
- Alessandro Di Risio
- Alessandro Galazzi
- Alexander Dullenkopf
- Alexander Kiselev
- Alexander Tsarev
- Alexandra Pivkina
- Alexandra Vasquez
- Alexis Tabah
- Ali Kağnıcı
- Alida Moise
- Aline Ramalho
- Alinoy Lavy
- Alisha van Axel
- Alma Cani
- Alvaro Ortega Guerrero
- Amalia Corso
- Amber Markham
- Amelia Ferreira
- Amer Assiri
- Amilcar Garcia
- Amilcar Garcia
- Amit Gupta
- Amit Gupta
- Amy Collins
- Amy Thompson
- Amy Walsh
- Amylkar Garay Reyes
- Amylkar José Garay Reyes
- Ana Alabart Llinas
- Ana Alícia Velarde Pineda
- Ana Bantar
- Ana Belén Curto Polo
- Ana Belén Sánchez de la Ventana
- Ana Diaz
- Ana Diaz
- Ana Isabel Clement
- Ana Laura Gonzalez
- Ana Lucia Vitti Ronchini
- Ana Margarida Feranandes
- Ana María De Pablo
- Ana Pascual-Bielsa
- Ana Tavares
- Ana Vochin
- Ana Wensell Fernández
- Anastasia Spyropoulou
- Anastasio Espejo Cano
- Andeas Stübner
- Andrea Bruni
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Giampaoletti
- Andrea Martonova
- Andrea Martonova
- Andrea McDonnell
- Andrea McLucas
- Andrej Markota
- Andrijan Kartalov
- Andréa Maria Laizner
- Andréa Maria Laizner
- Andréa Maria Laizner
- Ane Stenset
- Angela Trposak
- Angelica Olivetto de Almeida
- Anisette Hoegenhaven
- Anita Alias
- Anita Jans
- Anita Vuković
- Anita-Chrysolyte Kusi-Appiah
- Anja Diers
- Anja Hansen
- Ann-Sofie Malvemyr
- Anna Alexandrou
- Anna Diaz
- Anna Efthymiou
- Anna Kyriakoudi
- Anna Leonova
- Anna Vita Bruno
- Anne Fishman
- Anne Langvad
- Anne Marie Kodal
- Anne Sofie Bomholt Pedersen
- Anne Williams
- Anne-Sophie Debue
- Annette Carey
- Annette Toellefsen
- Anthony Adenekan
- Anthony Radavidson
- Antigoni Karathanou
- Anton Turčan
- Antonella Cotoia
- Antonella Mo
- Antoni Margarit Ribas
- Antonia Liarmakopoulou
- Antonija Petosic
- Antonino Rizzo
- Antonio Abdala
- Antonio Barone
- Antonio Landaverde
- Antonio Manzo
- Antonio Margarit Ribas
- Antony Eneas
- Apostolos Bakas
- Arena Raimondo
- Arif Moghal
- Aristeidis Vakalos
- Arlette Van Den Elst
- Armanda Bozena
- Armando Schmukler
- Armorel Salberg
- Artemis Patsalos
- Arturo Briva
- Arvind Baronia
- Asbjorn Blondal
- Ascanio Tridente
- Ashish K Khanna
- Ashish K Khanna
- Ashish Khanna
- Ashley Szabo Eltorai
- Ashok Sundai Raj
- Ashwaq Ali
- Asmah Zainudin
- Asu Ozgultekin
- Ata Mahmoodpoor
- Athena Lavrentieva
- Attilio Quaini
- Audrey Fioretti
- Audrey Massard
- Auke Reidinga
- Auli Palmu
- Avşar Zerman
- Aya Alabuzidi
- Ayako Noguchi
- Ayça Gümüş
- Azmin Huda Abdul Rahim
- Babangida John Sankey
- Badiola Hilario
- Banu Taşdemir
- Baoke Zhang
- Barbara Garcia
- Barbro Meland
- Bart Ramaker
- Basri Mat Nor
- Battsetseg Baasanjav
- Başar Erdivanli
- Başar Erdivanli
- Beatrice Pastore
- Begoña Zalba-Etayo
- Belen Burgos Conde
- Belinda Guadi-Gosh
- Ben Attwood
- Benjamin Bongiorno
- Benjamin Gerretsen
- Benoît Chinardet
- Berenice Navarro
- Bernardo Panka
- Bernardo Panka
- Bernd Oliver Rose
- Bert Loef
- Betty Star Kampayana
- Beverley Thomas
- Beysim Özcan
- Beysim Özcan
- Bhagyesh Shah
- Biljana Kuzmanovska
- Bindu Thankamma
- Bing Song
- Binny Tuinstra
- Birgitte Fosser Johansen
- Birthe Husted
- Biyan Li
- Bjoern Monsen
- Bjorn Bratsberg
- Bodin Khwannimit
- Bogdan Raitsiou
- Bojan Jovanovic
- Bonnie Bowes
- Boğaç Özserezli
- Bram Kilapong
- Bram Kilapong
- Branislava Stefanovic
- Brian Marsh
- Brigitte Tejeda-Huezo
- Brita Fosser Olsen
- Britt Galaaen
- Britt Sjobo
- Britta Jepsen
- Bronagh Blackwood
- Bruno Miguel Bispo
- Bruno Sousa
- Bruno Sousa
- Brynja Rygvadottir
- Burhan Hadri
- Burhan Hadri
- Byung Ju Kang
- Caihong Hui
- Caiju Song
- Caitriona Cody
- Can Turan
- Carita Löfqvist
- Carlo Alberto Volta
- Carlos Alejandro Bascary
- Carlos Castro Delgado
- Carmel Chapman
- Carmel Georgiev
- Carmen Partera Luque
- Carmen Velasco Guillén
- Carole Boulanger
- Carole Boulanger
- Carole Brett
- Carolina Garzón-Tovar
- Carolina Palaez
- Caroline Lagerhäll
- Caroline O'Donnell
- Caroline Paillet
- Carrie Sona
- Casiano Barrera Groba
- Catalin Traian Guran
- Catarina Nunes
- Catarina Tingsvik
- Catherine Motherway
- Catherine O'Brien
- Catherine Smith
- Cathy Becker
- Catia Quagliotto
- Cecilia Inés Loudet
- Cecilia Loudet
- Celia Tirado
- Ceri Lynch
- Cesar Aponte
- Cesar Rodriguez Nuñez
- Chaiwut Sawawiboon
- Chaoqun Ma
- Charalampos Martinos
- Charalice Ramiro
- Charikleia Nikolaou
- Charlotte Carter
- Charlotte Young
- Charlotte Young
- Chen Yumei
- Cheng
- Chenghau Mu
- Chengxia Sun
- Cheryl Bealer
- Cheryl Davidson
- Chiara Gatti
- Chiara Megna
- Chiara Megna
- Cho Young-Jae
- Chris Gerome Ellazar
- Chris Smith
- Chrisi Diakaki
- Christian Ferretti
- Christian Frey
- Christian Theisen
- Christiana Chime
- Christine Fiedler
- Christine Sheehan
- Christophe Borin
- Christophe Giacardi
- Christopher Barnes
- Christopher Barnes
- Christopher Palfreeman
- Christopher Potestio
- Christos Christofis
- Christos Dragoumanis
- Chrysanthos Markoulias
- Chrysostomos Katsenos
- Chun Jie Xia
- Chunxia Li
- Cindy Barefield
- Cindy Pillard
- Cintia Valencia Hurtado
- Cinzia Borgognoni
- Claire Derbyshire
- Claire Randell
- Claire Reynolds
- Clara Hurtado
- Clara Santa Rita
- Clare Fielding
- Clare Howcroft
- Claude Sertznig
- Claudia Lizbeth Lopez Nava
- Claudia Martins
- Congcong Liu
- Constantina Constantinou
- Cristal April Jane Aperocho
- Cristian Quiroga
- Cristiana Mota Pinheiro
- Cristina Paños Espinosa
- Cristina Petrisor
- Cui Yuan
- Cynthia Xing
- Cyril Thix
- Cyril Thix
- Cédric Bruel
- Cédric Daubin
- Dagmar Holmquist
- Daira Gonzalez
- Daisy Mehay
- Dale Ventour
- Damei Wang
- Damien O'Connell Rosemary Finn
- Dana Tomescu
- Dana Tomescu
- Danca Lančaričová
- Daniel Blanco
- Daniel Horner
- Daniel Owens
- Daniel Sancho Muriel
- Daniela Alampi
- Daniela Carmen Filipescu
- Danielle Hacking
- Danil Baskakov
- Daria Rabarova
- Dassy Levy
- David De Bels
- David Higgins
- David Perez-Torres
- David Shaw
- Davide Massimo Ghioldi
- Dea Mahanes
- Debbie Noblezada-Uy
- Deborah Jibrin
- DeHong Lei
- Deirdre Doyle
- Dejan Veličković
- Delmiro Becker
- Delphine Ngo
- Demet Tok Aydin
- Detlef Kindgen-Milles
- Devrim Akdağ
- Deyan Cao
- Diana Alvarez
- Diane Barkas
- Dianne Figaro-Barclay
- Dick Nahar
- Diego Rolando Morocho Tutillo
- Dimitra Lepida
- Dimitrios Papadopoulos
- Dinko Tonkovic
- Dirk von Lewinski
- Dmitriy Galishevskiy
- Dmitry Sergeev
- Dolly Mabel Bordon Cabral
- Dominic Carney
- Donaldo S Arteta Arteta
- Dongfang Wei
- Dongliang Lin
- Dongmei Bai
- Dongshu Ni
- Donna Cummings
- Dorel Sandesc
- Dorothee Mueller
- Dorothy Terry
- Drammen Sykehus
- Dritan Muzha
- Dritan Muzha
- Duygu Kayar Calili
- Dylan De Lange
- Dylan De Lange
- Edda Johansen
- Edwin Chapeta
- Egide Buregeya
- Egidija Bielskute
- Eileen Gilder
- Eirini Pantiora
- Eirini Papageorgiou
- Eirini-Chysovalanto Patsiou
- Ekaterina Tokareva
- Elaine Barros
- Elaine Thorpe
- Eleanor Santiago
- Elena Molinos
- Eleni Achilleos
- Eliane Mazocoli
- Elie Gharios
- Elif Erdogan
- Elif Erdogan
- Elin Kristoffersen
- Elin Mari Skorstad
- Elin Steffenak
- Elina Karjula
- Elisabet Gallart
- Elisabeth Wiborg
- Elisabetta Brizio
- Elizabeth Campbell
- Elizabeth Maidana
- Elizabeth Stones
- Ella Rokosh
- Elsa Afonso
- Elsa Afonso
- Emanuel Valgolio
- Emiliano Dean
- Emilio Maseda
- Emma Aves
- Emma Moreno Barreiro
- Emma Parkin
- Enas Soula
- Eneli Anvelt
- Enora Atchade
- Epaminontas Farmakis
- Erik Roman-Pognuz
- Erika Backlund Jansson
- Eryun Tian
- Esben Straede
- Esteban Milioto
- Estefania Orozco
- Estefanía Prol-Silva
- Estevão Lafuente
- Etienne De Montmollin
- Eugenio Garofalo
- Eugenio Martinez-Hurtado
- Eugeniya Larina
- Eulália Luis
- Eumorfia Kondili
- Eunice Tole
- Eva Joelsson-Alm
- Eva Joelsson-Alm
- Eva Åkerman
- Eva Åkerman
- Evangelia Michailidou
- Evdokia Sourla
- Evellyn Oliveira
- Evgeniy Zuev
- Evren Şentürk
- Ewa Wahlbom
- Ewa Wallin
- Fabienne Etourneau
- Fabio Capuzzi
- Fabio Guarracino
- Fan Yang
- Fanglan Wang
- Farid Zand
- Farshad Heidari
- Fatema Salman
- Fateme Jafaraghaee
- Fatemeh Zarei
- Fatiha Essardy
- Fatima Fernandes
- Fatima Ferreira
- Fatima Kasem El Ahmad
- Fatime Hawchar
- Faustina Excel Adipa
- Fausto Guerrero
- Faye Morren
- Fayez François Abillama
- Fayez François Abillama
- Federica Dellafiore
- Federica Mancini
- Federica Piergentili
- Federico Gordo
- Federico Iglesias
- Fei Ouyang
- Feifei Chen
- Feifei Luo
- Feifei Zhang
- Fekri Abroug
- Fengling Yang
- Ferdinand Aganon
- Fernando Avalos
- Fernando Baccaro
- Fernando Lipovestky
- Fernando Lipovesty
- Fernando Molinar
- Fernando Pablo Bertoletti
- Fernando Tapia
- Fethi Gül
- Fidelina Canete
- Filip Naumovski
- Filipo Binda
- Filippo Boroli
- Filpe Pires
- Fiona Coyer
- Fiona Coyer
- Fiona Coyer
- Fiona O'Shea
- Firas Ashour
- Flavia Ranalli
- Frances Dawn
- Frances Lin
- Frances Lin
- Frances Lin
- Frances Lin
- Francesca De Sanctis
- Francesca Paola Tranello
- Francesca Rubulotta
- Francesca Rubulotta
- Francesca Rubulotta
- Francesco D'Ambrosio
- Francesco Uccelli
- Francis Hannes
- Francisco Javier Saenz Abos
- Frank Bloos
- Frank Bloos
- Franklin Dean Cerezo
- François Philippart
- Fränk Gils
- Fumiya Kanda
- Fuqun Pan
- Fuying Ma
- Gabor Nardai
- Gabriel Enrique Rodriguez
- Gabriel Preda
- Gabriel Suen
- Gabriela Mendez
- Gao Chunhua
- Gari Slobodianiuk
- Garri Slobodianiuk
- Gavin D Leslie
- Gaëtan Plantefève
- Ged Williams
- Gen Meng
- Genci Hyska
- Georgios Gkiokas
- Georgios Papathanakos
- Geraldine Craig
- Gerry Fitzpatrick
- Ghaleb Almekhlafi
- Giacomo Castiglione
- Gian Domenico Giusti
- Giancarlo Abregal
- Giannoula Thoma
- Gilberto Felipe Vazquez de Anda
- Gilles Martin
- Gillian Berry
- Giorgia Rubulotta
- Giovanni Scire
- Glenda Rooney
- Gloria Alvarenga
- Gloria Montaldi
- Gonzalo Martín Alvarez
- Gonzalo Pagella
- Gordana Pavlisa
- Gordana Zivanovic-Posilovic
- Grace Lacaden
- Graciela Del Valle Gimenez
- Graciela Zakalik
- Grit Henning
- Gro Anne Lunde
- Gro Ringstad Akselsen
- Guangyan Liu
- Guangyuan Gao
- Guanxiu Shi
- Guifang Du
- Guijun Bao
- Guillaume Besch
- Guillermo Muñiz Albaiceta
- Guiping Zhang
- Gulbahar Caliskan
- Gulsah Karaoren
- Gun Löf
- Gunilla Mattsson
- GuoXian Wang
- Guoxue He
- Guoyan Zhu
- Gustavo Andres Alvarez
- Gustavo Badariotti
- Guy François
- Gülseren Elay
- Hai Yin
- Hai Yun Wang
- Hailing Guo
- Haiyan Chen
- Haiyan Wang
- Hajer Ben Zahra
- Hakan Yilmaz
- Hanne Andresen
- Hanne Haugom
- Hanne Irene Jensen
- Hanne Irene Jensen
- Hansjoerg Waibel
- Harriet Judd
- Hasan Nabi Undar
- Hayriye Cankar Dal
- Hazem Ahmed
- Heather Byers
- Hege Bjorgen
- Hege Ostenjo
- Helen Baker
- Helen Derrick
- Helen Jaundoo
- Helen Williams
- Helena Behan
- Helena Cesar
- Helena Fernandez Alonso
- Hemena Čuljak
- Hernan Aguirre-Bermeo
- Hernan Aguirre-Bermeo
- Hervé Mentec
- Hervé Quintard
- Heung Bum Lee
- Hideaki Sakuramoto
- Hilary Twiggs
- Hilaryano Ferreira
- Hong Zhang
- Hong Zheng
- Hongjuan Chen
- Hongmei Liu
- Hongmei Qiao
- Hongsu Zhang
- Hongyan Shao
- Howe Yan
- Hrönn Birgisdottir
- Hrönn Birgisdóttir
- Hua Ji
- Huai Yang
- Huan Duan
- Hugo Perez
- Hui Min Zhao
- Hui Zhang
- Humberto Costa
- Humberto Gallegos-Perez
- Huseyin Arikan
- Hyacinth Harding-Goldson
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- Volkan Inal
- Volodymyr Babych
- Vongayi Ogbeide
- W Nazaruddin W Hassan
- Walid Naija
- Walid Sellami
- Walter Swinnen
- Wan Nasrudin Wan Ismail
- Wang Zhijuan
- Wangari Waweru-Siika
- Wangari Waweru-Siika
- Wangyan Jin
- Wei Sun
- Wei Wang
- Wei Wei
- Wei Zhang
- Wei Zhang
- Weilian Yuan
- Weiwei Li
- Wenche Arntsen
- Wendy Brown
- Wendy Chaboyer
- Wendy Chaboyer
- Wendy Milner
- Wenjie Ju
- Wenmei Wang
- Wenmin Chen
- Wenwen Zhao
- Wenzhen Cao
- Wesal Ali Belkhair
- Willem Dieperink
- Windu Baskoro
- Won-Yeon Lee
- Wu Yuchen
- Xia Cui
- Xia Huang
- Xianhong Zheng
- Xianping Luo
- Xiao Fang Tian
- Xiao Xu
- XiaoChun Hu
- Xiaodi Liu
- Xiaofang Luo
- Xiaohan Li
- Xiaohan Li
- Xiaojun Wu
- Xiaoli Yan
- Xiaomin Wang
- Xiaoqiong Deng
- Xiaowu Bai
- Xiaoyan Chen
- Xiaoyan Chen
- Xiaoying Wu
- XiaoZhe Liu
- Ximena Villanueva
- Xingguo Li
- Xinhua Xia
- Xinhua Xia
- Xinjian Li
- Xinran Ding
- Xinxia Li
- Xinxia Li
- Xiuhua Fang
- Xiuhua Fang
- Xiujuan Xue
- XiuMei Liu
- Xiuying Yao
- Xiyan Wei
- Xu Peipei
- Xue Lin
- Xue Qin Li
- Xuejuan Liang
- XueLian Liu
- Xuelian Pang
- Xuelian Xu
- Xueping Jiao
- Yajun Ding
- Yakubu H Yakubu
- Yali Zhang
- Yalım Dikmen
- Yalım Dikmen
- Yalim Dikmen
- Yan Gao
- Yan Li
- Yan Liu
- Yan Liu
- Yan Long
- Yan Wan
- Yan Wang
- Yan Xiao
- Yan Xie
- Yan Xu
- Yan Yan
- Yanfei Long
- Yang Lei
- Yang Liu
- Yang Wu
- Yang Xiaoyan
- Yanhong Di
- Yanhua Hao
- Yani Tian
- Yanlan Yao
- Yanling Shen
- Yanman Jian
- Yanmei Gu
- Yanming Ding
- Yann Le Guen
- Yanping Yang
- Yasser Mandourah
- Yenny Cardenas
- Yenny Cardenas
- Yesim Serife Bayraktar
- Yin He
- Ying Cao
- Ying Li
- Ying Liu
- Ying Wang
- Ying Wei
- Ying Zhang
- Yingjuan Zhao
- Yingli Wang
- Yinhua Guo
- Yolanda Mendiara
- YongXia Yang
- Yoshimasa Nishime
- Yoshiro Hayashi
- Youjin Chang
- Youru Jiang
- Youssef Zied Elhechmi
- Ysica Acosta
- Yu Chao
- Yu Han
- Yu Liu
- Yu Liu
- Yue Sun
- Yue Ying Gong
- Yuming Zhou
- Yun Su Sim
- Yun Wu
- Yunchun Dong
- Yunfeng Xiong
- Yupeng Liu
- Yuping Wang
- Yuxia Huo
- Yuxia Wang
- Yuxia Yuan
- Yvan Fleury
- Yvonne Andersen
- Zainab Ateya
- Zaneta Bogoevska-Miteva
- Zeya Shi
- Zhang Zhigang
- ZhangShuangzi Li
- ZhangXia Feng
- Zhaoxia Feng
- Zhaoxing Dai
- Zhenxia Zhang
- Zhihong Chen
- Zhiru Yao
- Zhixia Jiang
- ZhiXia Jiang
- Zhixia Tian
- Zhu Jun Yu
- Zhuqing Li
- Zied Hajjej
- Zijing Wu
- Zsuzsann Ágoston
- Zu Qing Cao
- Zulkifli Zulkifli
- Ângela Lima
- Publication venue
- Intensive Care Medicine
- Publication date
- 29/08/2020
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
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Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
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- Baker Nerilee
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- Balbay Abidin Oner
- Balon Sandrine
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- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
- Bastani Styliani
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- Baxter Karen
- Bayraktar Yesim Serife
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- Bean Sarah
- Becker Cathy
- Becker Delmiro
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- Belkhair Wesal Ali
- Belskiy Vladislav
- Ben-Hamouda Nawfel
- Ben-Jacob Talia
- Benbenishty Julie
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- Bertoletti Fernando Pablo
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- De lange Dylan
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- D’Ambrosio Francesco
- D’Ambrosio Paolo
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- Efe Serdar
- Efthimiou Aikaterini
- Efthymiou Anna
- Egi Moritoki
- Egorova Natalya
- Ei Poe Poe
- Elatrous Souheil
- Elay Gülseren
- Elgammudi Mala
- Elhadi Ahmed
- Elhadi Muhammed
- Elhechmi Youssef Zied
- Elkhayari Mina
- Ellazar Chris Gerome
- Eller Philipp
- Eltorai Ashley Szabo
- Enamorado Judy
- Enamorado Judy Enamorado
- Eneas Antony
- Eng Timothy
- Erdivanli Başar
- Erdogan Elif
- Eroglu Ahmet
- Ershova Olga
- Escalante Rosana Gabriela
- Espinosa Cristina Paños
- Esposito Romina
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- Fernandez Maria Cristina Iglesias
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- Higgins David
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- Hirao Akemi
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- Honoré Patrick M.
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- Jaschinski Ulrich
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- Kanakaki Sofia
- Kanda Fumiya
- Kang Byung Ju
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- Kapoor Ritoo
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- Karabacak Pınar
- Karakurt Sait
- Karamchandani Kunal
- Karaoren Gulsah
- Karathanou Antigoni
- Karjula Elina
- Kartalov Andrijan
- Kataoka Jun
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- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
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- Yang Fengling
- Yang Huai
- Yang Jing
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- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
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- Yeon-Joo Lee
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- Yilmaz Hakan
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- Yu Min
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- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- 'Organisation for Economic Co-Operation and Development (OECD)'
- Publication date
- 26/02/2021
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Recommended from our members
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
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- Zhao Ronghua
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- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
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- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- Intensive Care Medicine
- Publication date
- 09/04/2021
- Field of study
The original version of this article unfortunately contained a mistake
Structure simplification of the Securinine skeleton reveals the importance of BCD ring system for the cytotoxic activity on HCT116 and HL60 cell lines
- Publication venue
- 'Elsevier BV'
- Publication date
- 12/02/2022
- Field of study
International audienceFunction-oriented molecular editing of the polycyclic scaffold of securinine led to the preparation of a library of simplified analogs that have been evaluated for their cytotoxicity potential against HCT116 and HL60 human cell lines. Chemical diversity at the C14 position (securinine numbering) was generated through the site-selective γ-iodination followed by Pd-catalyzed Sonogashira and Suzuki-Miyaura reactions. To explain the selectivity in the iodination step, a reaction mechanism has been proposed. Surprisingly, the piperidine ring (ring A) of the securinine skeleton has been found to be irrelevant for the cytotoxic activity. Based on this finding, the pharmacophoric core of securinine could be simplified to the key BCD motif. The nature of the substituent at the nitrogen can vary from a methyl or an isobutyl group to a benzyl or a carbamate moiety. Interestingly, the N-benzyl substituted simplified analog exhibited the same cytotoxic activity as the parent compound securinine. This functional group tolerance paves the way for the installation of reactive handles for the synthesis of molecular probes for target identification
Nouveaux lipides amphiphiles ramifiés
- Publication venue
- HAL CCSD
- Publication date
- 25/09/2015
- Field of study
The present invention relates to novel branched amphiphilic lipids. In particular, the present invention relates to novel branched amphiphilic lipids of general formula (II). The present invention also provides a method for synthesis of said compounds of formula (II) from unsaturated amphiphilic compounds of general formula (I). The invention also relates to the use of compounds of general formula (II) and lipoplexes obtained by formulating the compounds of general formula (II) for applications, including transfection, in which improved melting properties are sought.The invention relates to novel branched amphiphilic lipids. The invention specifically relates to novel branched amphiphilic lipids of general formula (II). The invention also relates to a method of synthesis for said compounds of formula (II), from unsaturated amphiphilic compounds of general formula (I). The invention further relates to the use of the compounds of general formula (II) and lipoplexes obtained by formulation of the compounds of general formula (II) for applications, particularly transfection, in which improved fusion properties are desired
Ultra-low-energy catalytic degradation of ozone by off-stoichiometric delafossite Cu–Cr–O for highly selective low-temperature solid-state O3 sensors
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/06/2023
- Field of study
Off-stoichiometric copper-chromium delafossite featuring giant catalytic degradation of ozone is demonstrated for the very first time. This leads to the reversible low-temperature detection of ozone onto resistive thin-film devices to values as low as 50 ppb. The selectivity when compared with molecular oxygen is also evidenced. Near-Atmospheric Pressure X-Ray Photoelectron Spectroscopy led to the understanding of the ozone - Cu0·66Cr1·33O2 surface reaction. The partial oxidation of copper into Cu2+ dependence on the ozone concentration is for the first time revealed. The apparition of a new peak associated with chemisorbed oxygen proves that the specific sub-stochiometric copper sites of the delafossite phase are driving the efficient and selective catalytic decomposition of ozone into monoatomic oxygen at the neat surface of thin films. The sensing response in ambient air is not limited by ozone decomposition but by the number of available adsorption sites. This work discloses pioneering results for the sensing networks integration of competitive ozone sensors based on Cu0·66Cr1·33O2