Oblate-prolate transition in odd-mass light mercury isotopes

Anomalous isotope shifts in the chain of light Hg isotopes are investigated by using the Hartree-Fock-Bogoliubov method with the Skyrme SIII, SkI3 and SLy4 forces. The sharp increase in the mean-square radius of the odd mass $^{181-185}$Hg isotopes is well explained in terms of the transition from an oblate to a prolate shape in the ground state of these isotopes. We discuss the polarization energy of time-odd mean-field terms in relation to the blocked level by the odd neutron.Comment: 25 pages including 19 postscript figures; accepted for publication in Nuclear Physics

Systematic decay studies of even-even 132−138132-138^Nd, 144−158144-158^Gd, 176−196176-196^Hg and 192−198192-198^Pb isotopes

The alpha and cluster decay properties of the $132-138$^Nd, $144-158$^Gd, $176-196$^Hg and $192-198$^Pb even-even isotopes in the two mass regions A = 130-158 and A = 180-198 are analysed using the Coulomb and Proximity Potential Model. On examining the clusters at corresponding points in the cold valleys (points with same A_2) of the various isotopes of a particular nucleus we find that at certain mass numbers of the parent nuclei, the clusters emitted are getting shifted to the next lower atomic number. It is interesting to see that the change in clusters appears at those isotopes where a change in shape is occurring correspondingly. Such a change of clusters with shape change is studied for the first time in cluster decay. The alpha decay half lives of these nuclei are computed and these are compared with the available experimental alpha decay data. It is seen that the two are in good agreement. On making a comparison of the alpha half lives of the normal deformed and super deformed nuclei, it can be seen that the normal deformed $132$^Nd, $176-188$^Hg and $192$^Pb nuclei are found to be better alpha emitters than the super deformed (in excited state) $134,136$^Nd, $190-196$^Hg and $194$^Pb nuclei. The cluster decay studies reveal that as the atomic number of the parent nuclei increases the N \neq Z cluster emissions become equally or more probable than the N=Z emissions. On the whole the alpha and cluster emissions are more probable from the parents in the heavier mass region (A=180-198) than from the parents in the lighter mass region (A= 130-158). The effect of quadrupole ({\beta}_2) and hexadecapole ({\beta}_4) deformations of parent and fragments on half life times are also studied.Comment: 42 pages,19 figure

Atomic mass measurements of short-lived nuclides around the doubly-magic 208Pb

Accurate atomic mass measurements of neutron-deficient and neutron-rich nuclides around the doubly-magic 208Pb and of neutron-rich cesium isotopes were performed with the Penning trap mass spectrometer ISOLTRAP at ISOLDE/CERN. The masses of 145,147Cs, 181,183Tl, 186Tlm, 187Tl, 196Tlm, 205Tl, 197Pbm, 208Pb, 190 to 197Bi, 209,215,216Bi, 203,205,229Fr, and 214,229,230Ra were determined. The obtained relative mass uncertainty in the range of $2 \cdot 10^{-7}$ to $2 \cdot 10^{-8}$ is not only required for safe identification of isomeric states but also allows mapping the detailed structure of the mass surface. A mass adjustment procedure was carried out and the results included into the Atomic Mass Evaluation. The resulting separation energies are discussed and the mass spectrometric and laser spectroscopic data are examined for possible correlations.Comment: 40 pages, 20 figures, accept. for publication in Nucl. Phys.

Desenvolvimento e Validação de método não destrutivo de determinação de nitrogênio proteico em vacina de febre amarela por espectroscopia de infravermelho próximo com calibração multivariada

Submitted by Repositório Arca ([email protected]) on 2019-05-09T18:44:58Z No. of bitstreams: 1 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5)Approved for entry into archive by Simone Teixeira ([email protected]) on 2019-12-13T19:31:42Z (GMT) No. of bitstreams: 2 Dissertação_Vanessa_Emídio_Dabkiewicz.pdf: 5138955 bytes, checksum: 4eb59555b1366d2ae4c0e32bde10e7c8 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5)Made available in DSpace on 2019-12-13T19:31:42Z (GMT). No. of bitstreams: 2 Dissertação_Vanessa_Emídio_Dabkiewicz.pdf: 5138955 bytes, checksum: 4eb59555b1366d2ae4c0e32bde10e7c8 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2016Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Rio de Janeiro, RJ, Brasil.A vacina febre amarela (atenuada) é o meio mais eficaz para prevenir e controlar essa doença. E segundo registros recentes, preocupa sua possível reemergência, refletindo no aumento da solicitação da vacina, tanto pelo Ministério da Saúde para áreas nacionais, quanto para a exportação.O conteúdo de proteína total é um fator de influência na tolerância a este imunobiológico, devendo ser monitorado o limite máximo exigido pela legislação, por meio do teste de nitrogênio proteico; realizado através do método de Kjeldahl, cujas desvantagens incluem o uso de reagentes químicos, a geração de resíduos e um longo tempo de análise. Diante da importância atribuída ao teste de nitrogênio proteico, no controle do produto final da vacina, é clara a motivação para o desenvolvimento e validação deste trabalho. Dentro das diretrizes da boa prática de fabricação (BPF) e fundamentos de vigilância sanitária, foi contemplada a espectroscopia do infravermelho próximo (NIR) com reflectância difusa, associada à calibração multivariada, como uma alternativa para o método clássico. A calibração multivariada mais apropriada foi alcançada para o método mínimos quadrados parciais (PLS) com tratamento de correção multiplicativa de sinal (MSC) e dados centrados na média (CM), utilizando um número mínimo de variáveis latentes igual a 1, com menor valor da raiz quadrada do erro médio quadrático de previsão (0,00334) associado ao maior valor de percentual (90%) de amostras com exatidão na faixa de recuperação de 95 a 105%, na região de 4000-5184 cm-1. O modelo teve comportamento nas suas previsões, considerado repetitivo com um valor de HorRat menor que 2, e com desvio padrão relativo menor que 5%. Os critérios de aceitação foram satisfatórios, indicando precisão intermediária adequada. O método não foi considerado robusto para a temperatura de 27°C, mas robusto para as temperaturas avaliadas (22°, 24° e 25°C), para todos os tempos de degelo avaliados (10 minutos a 6 horas), para a troca da lâmpada do instrumento e para a variação da posição de leitura do frasco da amostra. A recuperação para valores de incremento de 0,02 mg/dose em nitrogênio proteico, com adição do padrão de ovoalbumina às amostras, apresentou percentuais entre 95 a 105%. A incerteza dos resultados da metodologia analítica do Kjeldahl (0,002345 mg/dose), representou uma contribuição significativa de 54% no resultado da incerteza dos resultados da calibração multivariada (0,002867mg/dose). Essa avaliação reflete a forte influência da confiabilidade dos valores de referência. A espectroscopia NIR apresentou vantagens sobre o método Kjeldahl, pois permitiu a eliminação do uso de reagentes perigosos, a redução do tempo total de análise e eliminou a geração de resíduos. A análise pela técnica espectroscópica, por ser não destrutiva, possibilita o reuso das amostras para estudo de estabilidade da vacina. Finalmente, este trabalho apresentou a implementação e validação de modelos multivariados, através de uma robusta técnica de espectroscopia de infravermelho próximo, para determinação de nitrogênio proteico. Mostrando-se uma alternativa viável ao método tradicional e uma possível ferramenta orientativa, para estudos posteriores na área de controle de qualidade, voltadas às exigências da vigilância sanitária.The yellow fever vaccine (attenuated) is the most effective way to prevent and control the disease. And according to recent records, concerns its possible reemergence, reflecting the increased request by both the Ministry of Health to national areas , and for export. The total protein content is a factor influencing the tolerance to this immunobiological and should be monitored the limit required by law, through the protein nitrogen test; performed by the Kjeldahl method, which disadvantages include the use of chemical reagents, waste generation and a long analysis time. Given the importance attached to the protein nitrogen test in control of the final product of the vaccine is a clear motivation for the development and validation of this work. Within the guidelines of good manufacturing practice (GMP) and health surveillance foundations, was awarded the near infrared spectroscopy with diffuse reflectance, connected with multivariate calibration as an alternative to the traditional method. The most appropriate multivariate calibration has been achieved for the PLS method and MSC, CM treatment, using a minimum number of latent variables equal to 1, less RMSEP value (0.00330) associated with the highest percentage value (91%) samples exactly a 95 to 105%, recovery band in the region of 4000-5184 cm-1. The model had behavior in their forecasts, considered repetitive with less Horrat value than 2, and relative standard deviation less than 5%. The acceptance criteria were satisfactory, indicating adequate intermediate precision. The method is not considered to be robust to 27° C, but robust to measured temperatures (22°, 24° and 25° C) for all time evaluated thaw (10 minutes to 6 hours) for the exchange instrument lamp and the variation of the sample vial reading position. The recovery increased to values of 0.02 mg/dose in protein nitrogen, with standard addition of the ovalbumin samples showed percentages between 95 and 105%. The uncertainty of the result of the Kjeldahl analytic methodology (0,002345 mg/dose), was a significant contribution of 54% in the uncertainty of the result of multivariate calibration (0,002867 mg/dose). This assessment reflects the strong influence of the reliability of the reference values. NIR spectroscopy showed advantages over the Kjeldahl method, because it allowed the elimination of the use of hazardous reagents, the reduction in the total analysis time and eliminated the generation of residues (leavings). The analysis by spectroscopic technique by been non-destructive, enables the reuse of samples for study of vaccine stability. Finally, this work presented the implementation and validation of multivariate models, through a robust technique of near infrared spectroscopy for the determination of protein nitrogen, proving a viable alternative to the traditional method and a possible tool for guidance for further studies in the quality control area, geared to the demands of health surveillance

Spiżarnia wiejska obywatelska, czyli praktyczne przepisy porządnego i należytego, tak utrzymania, jako i urządzenia spiżarni--pewnych i łatwych sposobów konserwowania wszelkich artykułow żywności, do użytku i wygody człowieka służących, tudzież, dokładne sposoby robienia wszelkich gatunków pekieflejszów, wędlin, salcesonów, octu, marynaty, marmulady, konfitur, jako też rozmaitych naliwek, wódek, likierów, farbowania cukrów i rzeczy innych, zupełość spiżarni stanowiących /

Reprint. Originally published: Wilno : w Drukarni A. Marcinkowskiego, 1838.Mode of access: Internet