Stressors in anaesthesiology: development and validation of a new questionnaire: A cross-sectional study of Portuguese anaesthesiologists

BACKGROUND: Stress in anaesthesiologists is a common and multifactorial problem related to patients, colleagues and organisations. The consequences of stress include depression, work-home conflicts and burnout. Reduction in stress can be achieved by reducing the number and magnitude of stressors or by increasing resilience strategies. OBJECTIVES: We have created the self-reporting 'Stress Questionnaire in Anaesthesiologists' (SQA), to qualify the sources of stress in anaesthesiologists' professional lives, and measure the level of associated stress. Our study aimed to develop and validate the SQA using exploratory and confirmatory factor analyses. Construct validity was assessed through correlations between SQA and negative psychological outcomes as well as by comparing perception of stress among different known groups. DESIGN: A questionnaire-based cross-sectional, correlational, observational study. SETTINGS: The study was conducted between January 2014 and December 2014, throughout different anaesthesia departments in Portuguese hospitals. Data collection was from a representative subset at one specific time point. PARTICIPANTS: A sample of 710 anaesthesia specialists and residents from Portugal. MAIN OUTCOME MEASURES: The primary outcome measure was to identify specific stressors in anaesthesiologists. Secondary outcome was the association between stressors and burnout, depression symptoms, anxiety, stress, rumination, satisfaction with life and functional impairment. RESULTS: The exploratory analysis showed the SQA is a tri-dimensional instrument and confirmatory analysis showed the tri-dimensional structure presented good model fit. The three dimensions of SQA correlated positively with other stress measures and burnout, but negatively with satisfaction with life. CONCLUSION: SQA is a well adjusted measure for assessing stressors in anaesthesia physicians and includes clinical, organisational and team stress factors. Results showed that the SQA is a robust and reliable instrument.info:eu-repo/semantics/publishedVersio

Effect of rainfall patterns on soil surface CO(2 )efflux, soil moisture, soil temperature and plant growth in a grassland ecosystem of northern Ontario, Canada: implications for climate change

BACKGROUND: The effect of rainfall patterns on soil surface CO(2 )efflux, soil moisture, soil temperature and plant growth was investigated in a grassland ecosystem of northern Ontario, Canada, where climatic change is predicted to introduce new precipitation regimes. Rain shelters were established in a fallow field consisting mainly of Trifolium hybridum L., Trifolium pratense L., and Phleum pratense L. Daytime ambient air temperatures within the shelters increased by an average of 1.9°C similar to predicted future increases in air temperatures for this region. To simulate six precipitation regimes which cover the maximum range to be expected under climate change, a portable irrigation system was designed to modify the frequency of monthly rainfall events with a constant delivery rate of water, while maintaining contemporary average precipitation volumes. Controls consisted of blocks irrigated with frequencies and total monthly precipitation consistent with the 25 year average rainfall for this location. RESULTS: Seasonal soil moisture correlated with soil surface CO(2 )efflux (R = 0.756, P < 0.001) and above ground plant biomass (R = 0.447, P = 0.029). By reducing irrigation frequency, soil surface CO(2 )efflux decreased by 80%, P < 0.001, while soil moisture content decreased by 42%, P < 0.001. CONCLUSIONS: Manipulating the number of precipitation events and inter-rainfall intervals, while maintaining monthly rainfall averages impacted CO(2 )efflux and plant growth. Even with monthly rainfall averages that are similar to contemporary monthly precipitation averages, decreasing the number of monthly rainfall events reduced soil surface CO(2 )efflux and plant growth through soil moisture deficits. Although many have speculated that climate change will increase ecosystem productivity, our results show that a reduction in the number of monthly rainfall events while maintaining monthly averages will limit carbon dynamics

A panel of human lung carcinoma lines: establishment, properties and common characteristics.

A panel of human lung carcinoma lines representing the four main histological types (squamous, small-cell, large-cell and adenocarcinoma), and derived from both primary and metastatic sites, has been established in xenograft and in tissue culture. The highest take rates were achieved when biopsy specimens were obtained from large tumour masses and cultured lines were most readily established after preliminary passages as xenografts. The established lines exhibited an overlapping spectrum of biochemical and morphological characteristics, and showed a tendency to change from one cell type to another, in keeping with the concept of a common endodermal cell of origin. Radiation resistance appeared to be related to the large-cell phenotype

West African equatorial ionospheric parameters climatology based on Ouagadougou ionosonde station data from June 1966 to February 1998

This study is the first which gives the climatology of West African equatorial ionosphere by using Ouagadougou station through three solar cycles. It has permitted to show the complete morphology of ionosphere parameters by analyzing yearly variation, solar cycle and geomagnetic activity, seasonal evolution and diurnal development. This work shows that almost all ionospheric parameters have 11-year solar cycle evolution. Seasonal variation shows that only &lt;I&gt;fo&lt;/I&gt;F2 exhibits annual, winter and semiannual anomaly. &lt;I&gt;fo&lt;/I&gt;F2 seasonal variation has permitted us to identify and characterize solar events effects on F2 layer in this area. In fact (1) during quiet geomagnetic condition &lt;I&gt;fo&lt;/I&gt;F2 presents winter and semiannual anomalies asymmetric peaks in March/April and October. (2) The absence of winter anomaly and the presence of equinoctial peaks are the most visible effects of fluctuating activity in &lt;I&gt;fo&lt;/I&gt;F2 seasonal time profiles. (3) Solar wind shock activity does not modify the profile of &lt;I&gt;fo&lt;/I&gt;F2 but increases ionization. (4) The absence of asymmetry peaks, the location of the peaks in March and October and the increase of ionization characterize recurrent storm activity. F1 layers shows increasing trend from cycle 20 to cycle 21. Moreover, E layer parameters seasonal variations exhibit complex structure. It seems impossible to detect fluctuating activity effect in E layer parameters seasonal variations but shock activity and wind stream activity act to decrease E layer ionization. It can be seen from Es layer parameters seasonal variations that wind stream activity effect is fairly independent of solar cycle. E and Es layers critical frequencies and virtual heights diurnal variations let us see the effects of the greenhouse gases in these layers

Critical exponents for the homology of Fortuin-Kasteleyn clusters on a torus

A Fortuin-Kasteleyn cluster on a torus is said to be of type $\{a,b\}, a,b\in\mathbb Z$, if it possible to draw a curve belonging to the cluster that winds $a$ times around the first cycle of the torus as it winds $-b$ times around the second. Even though the $Q$-Potts models make sense only for $Q$ integers, they can be included into a family of models parametrized by $\beta=\sqrt{Q}$ for which the Fortuin-Kasteleyn clusters can be defined for any real $\beta\in (0,2]$. For this family, we study the probability $\pi({\{a,b\}})$ of a given type of clusters as a function of the torus modular parameter $\tau=\tau_r+i\tau_i$. We compute the asymptotic behavior of some of these probabilities as the torus becomes infinitely thin. For example, the behavior of $\pi(\{1,0\})$ is studied along the line $\tau_r=0$ and $\tau_i\to\infty$. Exponents describing these behaviors are defined and related to weights $h_{r,s}$ of the extended Kac table for $r,s$ integers, but also half-integers. Numerical simulations are also presented. Possible relationship with recent works and conformal loop ensembles is discussed.Comment: References and one figure adde

Procedures and Frequencies of Embalming and Heart Extractions in Modern Period in Brittany. Contribution to the Evolution of Ritual Funerary in Europe.

The evolution of funeral practices from the Middle Ages through the Modern era in Europe is generally seen as a process of secularization. The study, through imaging and autopsy, of two mummies, five lead urns containing hearts, and more than six hundred skeletons of nobles and clergymen from a Renaissance convent in Brittany has led us to reject this view. In addition to exceptional embalming, we observed instances in which hearts alone had been extracted, a phenomenon that had never before been described, and brains alone as well, and instances in which each spouse's heart had been placed on the other's coffin. In some identified cases we were able to establish links between the religious attitudes of given individuals and either ancient Medieval practices or more modern ones generated by the Council of Trent. All of these practices, which were a function of social status, were rooted in religion. They offer no evidence of secularization whatsoever

A reference relative time-scale as an alternative to chronological age for cohorts with long follow-up

Background: Epidemiologists have debated the appropriate time-scale for cohort survival studies; chronological age or time-on-study being two such time-scales. Importantly, assessment of risk factors may depend on the choice of time-scale. Recently, chronological or attained age has gained support but a case can be made for a ‘reference relative time-scale’ as an alternative which circumvents difficulties that arise with this and other scales. The reference relative time of an individual participant is the integral of a reference population hazard function between time of entry and time of exit of the individual. The objective here is to describe the reference relative time-scale, illustrate its use, make comparison with attained age by simulation and explain its relationship to modern and traditional epidemiologic methods. Results: A comparison was made between two models; a stratified Cox model with age as the time-scale versus an un-stratified Cox model using the reference relative time-scale. The illustrative comparison used a UK cohort of cotton workers, with differing ages at entry to the study, with accrual over a time period and with long follow-up. Additionally, exponential and Weibull models were fitted since the reference relative time-scale analysis need not be restricted to the Cox model. A simulation study showed that analysis using the reference relative time-scale and analysis using chronological age had very similar power to detect a significant risk factor and both were equally unbiased. Further, the analysis using the reference relative time-scale supported fully-parametric survival modelling and allowed percentile predictions and mortality curves to be constructed. Conclusions: The reference relative time-scale was a viable alternative to chronological age, led to simplification of the modelling process and possessed the defined features of a good time-scale as defined in reliability theory. The reference relative time-scale has several interpretations and provides a unifying concept that links contemporary approaches in survival and reliability analysis to the traditional epidemiologic methods of Poisson regression and standardised mortality ratios. The community of practitioners has not previously made this connection