Coste energético del dribling en hockey sobre patines

El objetivo del presente estudio ha sido analizar y comparar el coste energético del dribling en hockey sobre patines con respecto a la acción de patinar. Doce jugadores amateurs bien entrenados han realizado, durante cinco minutos a 11, 13 y 15 km/h, patinaje solamente y patinaje mientras driblaban la bola con el stick. En ambos casos se evaluaron directamente y compararon consumo de oxígeno, ventilación, frecuencia cardíaca y nivel de percepción subjetiva del esfuerzo. Las variables fisiológicas fueron registradas mediante un analizador de gases portátil telemétrico (Cosmed K2) y un cardiotacómetro (Sport Tester PE4000). El coste energético se incrementa linealmente con la velocidad y, además, es superior en todos los casos al driblar la bola mientras se patina (17.50 ± 0.7 ml/kg.in vs 20.40 ± 0.61 inl/kg.m a 11 km/h; 19.23 ± 0.51 ml/kg.m vs 24.54 ± 0.76 ml/kg.m a 13 km/h; 24.84 ± 0.85 ml/kg.m vs 32.44 ± 0.7 ml/kg.m a 15 km/h). La ventilación y la frecuencia cardíaca muestran también una evolución similar. Los niveles de percepción subjetiva del esfuerzo son más altos al realizar el dribling que al patinar (p<.05) y, en ambos casos, también más elevados cuanto mayor es la velocidad (p<.05). Se puede concluir que el dribling de la bola en hockey al patinar aumenta significativamente el coste energético y la percepción subjetiva del esfuerzo con respecto a la acción de solamente patinar

Monitoring and Assisting Maternity-Infant Care in Rural Areas (Mamicare)

We present our project called MAMICare that is motivated by the alarming number of maternity and infant deaths in rural areas due mainly to a poor monitoring of pregnancy progress and lack of appropriate alerting mechanism in case of abnormal gestation evolution. We are proposing an information technology solution based on mobile devices, and health sensors such as ECG (electrocardiogram), stethoscope, pulse-oximeter, and blood-glucose meter to automatically collect relevant health data for a better monitoring of pregnant women. In this paper we address the current status of the maternity infant death problem especially in rural areas of Mexico. We review some applications of IT in health systems (known also as Electronic Health or simply e-Health) and discuss how these are related to our proposal and how they differ. In the paper we present our proposed solution and discuss the current status of our work

Comparison of visual and refractive results of Toric Implantable Collamer Lens with bioptics for myopic astigmatism

PURPOSE: To compare visual and refractive results of Toric Implantable Collamer Lens (TICL) and bioptics (ICL plus excimer corneal surgery) to treat myopic astigmatism. METHODS: Eighty-one eyes underwent TICL implantation and 83 eyes were treated with bioptics (corneal ablation was performed between 1.5 and 6 months after ICL implantation). Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refraction, adverse events, safety, and efficacy were evaluated 12 months postoperatively. RESULTS: At 12 months postoperatively, the mean spherical equivalent was -0.15 ± 0.36 diopters (D) in the TICL group and -0.08 ± 0.26 D in the bioptics group (p = 0.099). Sixty-six (81.5 %) and 78 (94.0 %) eyes were within ±0.50 D for TICL and bioptics groups, respectively. The mean Snellen UDVA was not statistically different between both procedures (p = 0.909); 53 (65.4 %) and 54 (65.1 %) eyes achieved at least 20/25 or better in TICL and bioptics groups, respectively. No eye had lost more than two lines of CDVA, and 32.1 % of eyes (26/81) in the TICL group and 57.8 % of eyes (48/83) in the bioptics group had better postoperative UDVA than preoperative CDVA (p < 0.001). Safety was not statistically different between groups (p = 0.464) while efficacy was significantly higher in the bioptics group (p = 0.000). Two eyes with a TICL were treated to correct TICL decentration. CONCLUSIONS: Bioptics showed slightly better outcomes in some clinical measures such as uncorrected visual acuity, efficacy, and refractive predictability. TICL implantation shows reliable results similar to bioptics. A single procedure with TICL implantation might be preferred, eliminating the inherent risks of laser treatments and the risks of a second surgical procedure.The authors have no proprietary interests in any of the materials mentioned in this article. This research was supported in part by a Universitat de Valencia Research Grant to Robert Montes-Mico (#SAF2009-13342 and #SAF2008-01114-E#) and Fundacao para a Ciencia e Tecnologia of Portugal through a Grant to Paulo Fernandes (#FCT-SFRH-BD-34303-2007#)

GESTIÓN ADMINISTRATIVA DEL ABASTECIMIENTO EN LAS INSTITUCIONES DEL SECTOR SALUD DEL ESTADO PERUANO./SUPPLY ADMINISTRATIVE MANAGEMENT IN HEALTH SECTOR INSTITUTIONS OF THE PERUVIAN STATE

RESUMEN El Objetivo de la presente investigación pretende: “...analizar las dificultades de la gestión administrativa del abastecimiento en las Instituciones del Sector Salud del Estado Peruano, con el propósito de identificar sus causas y proponer el uso de teorías y conocimientos científicos, que contribuyan a desarrollar una filosofía conceptual de modernización y de mejoramiento continuo...” Así mismo el Problema, exige responder ¿Se presentan o producen empirismos aplicativos, deficiencias, incumplimientos, carencias, y distorsiones en la gestión administrativa del abastecimiento en las Instituciones del Sector Salud del Estado Peruano? Para este fin, además de una visión retrospectiva y la descripción del tema planteado, se apela al uso de la estadística aplicada al campo social a través del método de regresión de mínimos cuadrados para realizar el respectivo análisis causa-efecto del caso formulado. ABSTRACT The aim of this investigation pretends “... analyze the difficulties of the administrative management of the healthcare supply in Peruvian state’s entities and propose the use of theories and scientific knowledge that will also help to develop a conceptual modernization and continuous improvement philosophy …” Likewise, the problem requires answering:  if there is  applicative empiricisms, deficiencies, failures, shortcomings and distortions in the administrative management of the healthcare supply in Peruvian state’s entitiesFor this aim, applied statistics is used to the social field through the weighted least squares regression method for a cause and effect analysis

Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-beta plaques

BACKGROUND: Increasing evidence for a direct contribution of astrocytes to neuroinflammatory and neurodegenerative processes causing Alzheimer’s disease comes from molecular and functional studies in rodent models. However, these models may not fully recapitulate human disease as human and rodent astrocytes differ considerably in morphology, functionality, and gene expression. RESULTS: To address these challenges, we established an approach to study human astrocytes within the mouse brain by transplanting human induced pluripotent stem cell (hiPSC)-derived astrocyte progenitors into neonatal brains. Xenografted hiPSC-derived astrocyte progenitors differentiated into astrocytes that integrated functionally within the mouse host brain and matured in a cell-autonomous way retaining human-specific morphologies, unique features, and physiological properties. In Alzheimer´s chimeric brains, transplanted hiPSC-derived astrocytes responded to the presence of amyloid plaques undergoing morphological changes that seemed independent of the APOE allelic background. CONCLUSIONS: In sum, we describe here a promising approach that consist of transplanting patient-derived and genetically modified astrocytes into the mouse brain to study human astrocyte pathophysiology in the context of Alzheimer´s disease

Determinación empírica de las competencias para el turismo sostenible

El presente trabajo tiene el propósito de determinar las escalas de medida de las competencias genéricas y específicas que permitan a directivos y trabajadores vinculados a la actividad turística en una localidad actuar en consonancia con el modelo de sostenibilidad que se persigue. Se recurrió al método de expertos. Se aplicó un test estadístico para medir la fiabilidad y validez de las escalas de medición. La muestra comprendió 97 directivos y 154 trabajadores de 25 organizaciones vinculadas a la actividad turística de la localidad de Viñales, Pinar del Río. Para el análisis de la fiabilidad se utilizó el Coeficiente Alpha de Cronbach y para el análisis de la validez se recurrió al Análisis Factorial. Se determinó que los directivos y trabajadores vinculados a la actividad turística de una localidad deben poseer seis competencias genéricas, siete competencias específicas de los directivos y cinco competencias específicas de los trabajadores, para contribuir a la sostenibilidad turística

Physical activity and clustered cardiovascular disease risk factors in young children: a cross-sectional study (the IDEFICS study)

&lt;p&gt;Background The relevance of physical activity (PA) for combating cardiovascular disease (CVD) risk in children has been highlighted, but to date there has been no large-scale study analyzing that association in children aged &#8804;9 years of age. This study sought to evaluate the associations between objectively-measured PA and clustered CVD risk factors in a large sample of European children, and to provide evidence for gender-specific recommendations of PA.&lt;/p&gt; &lt;p&gt;Methods Cross-sectional data from a longitudinal study in 16,224 children aged 2 to 9 were collected. Of these, 3,120 (1,016 between 2 to 6 years, 2,104 between 6 to 9 years) had sufficient data for inclusion in the current analyses. Two different age-specific and gender-specific clustered CVD risk scores associated with PA were determined. First, a CVD risk factor (CRF) continuous score was computed using the following variables: systolic blood pressure (SBP), total triglycerides (TG), total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-c) ratio, homeostasis model assessment of insulin resistance (HOMA-IR), and sum of two skinfolds (score CRFs). Secondly, another CVD risk score was obtained for older children containing the score CRFs + the cardiorespiratory fitness variable (termed score CRFs + fit). Data used in the current analysis were derived from the IDEFICS (‘Identification and prevention of Dietary- and lifestyle-induced health EFfects In Children and infantS’) study.&lt;/p&gt; &lt;p&gt;Results In boys &#60;6 years, the odds ratios (OR) for CVD risk were elevated in the least active quintile of PA (OR: 2.58) compared with the most active quintile as well as the second quintile for vigorous PA (OR: 2.91). Compared with the most active quintile, older children in the first, second and third quintiles had OR for CVD risk score CRFs + fit ranging from OR 2.69 to 5.40 in boys, and from OR 2.85 to 7.05 in girls.&lt;/p&gt; &lt;p&gt;Conclusions PA is important to protect against clustering of CVD risk factors in young children, being more consistent in those older than 6 years. Healthcare professionals should recommend around 60 and 85 min/day of moderate-to-vigorous PA, including 20 min/day of vigorous PA.&lt;/p&gt

Síndrome post-covid-19: manifestaciones clínicas más frecuentes

COVID-19 since its emergence in Wuhan, China, has spread and had a profound impact on the lives and health of individuals globally. As of July 4, 2021, there have been more than 183 million confirmed cases of SARS-CoV-2 and 3.97 million deaths globally. Post-COVID syndrome is the term used in patients who have recovered from SARS-CoV-2 but symptoms persist. These symptoms involve persistent physical disorders that produce conditioning in regular activities such as work and physical activity, it also produces cognitive sequelae, in many cases immunosuppression is persistent, many of the patients have pulmonary, cardiac and vascular fibrosis after having culminated with the phase of acute infection by COVID-19. Symptoms of post-COVID syndrome include fatigue, dyspnea, muscle pain, sleep disturbances, cognitive impairment, heart abnormalities, symptoms of post-traumatic stress disorder, concentration problems, and headache. This review summarises the most common symptoms of hospitalised and outpatient patients who have overcome acute SARS-CoV-2 infection, and discusses treatment guidelines for these patientsEl COVID-19 desde su aparición en Wuhan, China, se ha propagado y ha tenido un profundo impacto en la vida y la salud de los individuos a nivel mundial. Hasta el 4 de julio de 2021, se habían registrado más de 183 millones de casos confirmados de SARS-CoV-2 y 3,97 millones de muertes a nivel mundial. El síndrome post-COVID es el término empleado en los pacientes que se han recuperado del SARS-CoV-2 pero los síntomas persisten. Estos síntomas involucran trastornos físicos persistentes que producen condicionamiento en las actividades regulares como el trabajo y actividad física, también produce secuelas cognitivas, en muchos casos la inmunosupresión es persistente, muchos de los pacientes tienen fibrosis pulmonar, cardíaca y vascular después de haber culminado con la fase de infección aguda por COVID-19. Los síntomas del síndrome post- COVID incluyen fatiga, disnea, dolor muscular, trastornos del sueño, deterioro cognitivo, anomalías cardíacas, síntomas de trastorno de estrés postraumático, problemas de concentración y cefalea. Esta revisión resume los síntomas más frecuentes que cursan los pacientes hospitalizados y no hospitalizados que superaron la infección aguda por SARS-CoV-2, también se discute las guías terapéuticas para dichos pacientes

Collective Animal Behavior from Bayesian Estimation and Probability Matching

Animals living in groups make movement decisions that depend, among other factors, on social interactions with other group members. Our present understanding of social rules in animal collectives is based on empirical fits to observations and we lack first-principles approaches that allow their derivation. Here we show that patterns of collective decisions can be derived from the basic ability of animals to make probabilistic estimations in the presence of uncertainty. We build a decision-making model with two stages: Bayesian estimation and probabilistic matching.&#xd;&#xa;In the first stage, each animal makes a Bayesian estimation of which behavior is best to perform taking into account personal information about the environment and social information collected by observing the behaviors of other animals. In the probability matching stage, each animal chooses a behavior with a probability given by the Bayesian estimation that this behavior is the most appropriate one. This model derives very simple rules of interaction in animal collectives that depend only on two types of reliability parameters, one that each animal assigns to the other animals and another given by the quality of the non-social information. We test our model by obtaining theoretically a rich set of observed collective patterns of decisions in three-spined sticklebacks, Gasterosteus aculeatus, a shoaling fish species. The quantitative link shown between probabilistic estimation and collective rules of behavior allows a better contact with other fields such as foraging, mate selection, neurobiology and psychology, and gives predictions for experiments directly testing the relationship between estimation and collective behavior