2,503 research outputs found

    The demand for money in developing countries : assessing the role of financial innovation

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    Traditional specifications of money demand have commonly been plagued by persistent overprediction, implausible parameter estimates, andhighly autocorrelated errors. The authors argue that some of these problems stem from the failure to account for the impact of financial innovation. They estimate money demand for ten developing countries, using various proxies for financial innovations. They also assess the relative importance of this variable, finding financial innovation can be better modeled as a stochastic (random-walk) trend rather than a deterministic (time) trend. Financial innovation plays an important role in determining fluctuations of the demand for money. The importance of this role increases with the rate of inflation.Economic Theory&Research,Environmental Economics&Policies,Fiscal&Monetary Policy,Inequality,Energy and Environment

    Perturbation Expansion in Phase-Ordering Kinetics: II. N-vector Model

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    The perturbation theory expansion presented earlier to describe the phase-ordering kinetics in the case of a nonconserved scalar order parameter is generalized to the case of the nn-vector model. At lowest order in this expansion, as in the scalar case, one obtains the theory due to Ohta, Jasnow and Kawasaki (OJK). The second-order corrections for the nonequilibrium exponents are worked out explicitly in dd dimensions and as a function of the number of components nn of the order parameter. In the formulation developed here the corrections to the OJK results are found to go to zero in the large nn and dd limits. Indeed, the large-dd convergence is exponential.Comment: 20 pages, no figure

    Clinical outcomes of teicoplanin use in the OPAT setting.

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    Teicoplanin possesses several convenient properties for use in the delivery of outpatient parenteral antimicrobial therapy (OPAT) services. However, its use is not widespread and data on its efficacy in the OPAT setting are limited. Here we present a case series of patients undergoing OPAT care being treated by either teicoplanin-based (n = 107) or ceftriaxone-based (n = 191) antibiotic regimens. Clinical failure with teicoplanin occurred in five episodes of care (4.7%) compared with only two episodes of ceftriaxone-based OPAT care (1.0%). Teicoplanin-associated clinical failure was observed in 2 (33.3%) of 6 patients with Enterococcus infections compared with 3 (3.0%) of 101 patients with non-Enterococcus infections. Overall, there were four (2.9%) drug-related adverse events for teicoplanin and four (1.8%) for ceftriaxone, prompting a switch to teicoplanin in three patients. These findings support the continued use of teicoplanin in OPAT as well as its consideration in centres where it is not currently being offered

    Seeing environmental violence in deep time: perspectives from contemporary Mongolian literature and music

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    What does it mean to do violence in deep time? How is deep time evoked in our understanding of environmental harm? Environmental transformations have figured prominently in the recent history of Mongolia. Shifts in land use have been associated with severe pasture degradation, and the precarity of herding livelihoods has been a factor accelerating urbanization. Most recently, the intensification of mining activity has been a particular source of social and economic change. These contexts have led to a political and religious reevaluation of human relationships with the land. This article focuses on literary and musical interventions (particularly rap music in the first part of the article and the literary work of G. Mend-Ooyo in the later part) that draw attention to this changing relationship with the environment, which the article portrays as a potential rupture. We explore how these works domesticate deep time, nesting personal histories within the temporal depth of the landscape and crosshatching biographical, mythological, and geologic understandings of time. Yet we then see how this domestication comes to be threatened by developments that sever the relationship between people and land, leading to the disturbing prospect of being left stranded in the face of an inhospitable deep time

    Phase ordering in bulk uniaxial nematic liquid crystals

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    The phase-ordering kinetics of a bulk uniaxial nematic liquid crystal is addressed using techniques that have been successfully applied to describe ordering in the O(n) model. The method involves constructing an appropriate mapping between the order-parameter tensor and a Gaussian auxiliary field. The mapping accounts both for the geometry of the director about the dominant charge 1/2 string defects and biaxiality near the string cores. At late-times t following a quench, there exists a scaling regime where the bulk nematic liquid crystal and the three-dimensional O(2) model are found to be isomorphic, within the Gaussian approximation. As a consequence, the scaling function for order-parameter correlations in the nematic liquid crystal is exactly that of the O(2) model, and the length characteristic of the strings grows as t1/2t^{1/2}. These results are in accord with experiment and simulation. Related models dealing with thin films and monopole defects in the bulk are presented and discussed.Comment: 21 pages, 3 figures, REVTeX, submitted to Phys. Rev.

    Cation distribution in manganese cobaltite spinels Co3−xMnxO4 (0 ≤ x ≤ 1) determined by thermal analysis

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    Thermogravimetric analysis was used in order to study the reduction in air of submicronic powders of Co3−x Mn x O4 spinels, with 0 ≤ x ≤ 1. For x = 0 (i.e. Co3O4), cation reduction occurred in a single step. It involved the CoIII ions at the octahedral sites, which were reduced to Co2+ on producing CoO. For 0 < x ≤ 1, the reduction occurred in two stages at increasing temperature with increasing amounts of manganese. The first step corresponded to the reduction of octahedral CoIII ions and the second was attributed to the reduction of octahedral Mn4+ ions to Mn3+. From the individual weight losses and the electrical neutrality of the lattice, the CoIII and Mn4+ ion concentrations were calculated. The distribution of cobalt and manganese ions present on each crystallographic site of the spinel was determined. In contrast to most previous studies that took into account either CoIII and Mn3+ or Co2+, CoIII and Mn4+ only, our thermal analysis study showed that Co2+/CoIII and Mn3+/Mn4+ pairs occupy the octahedral sites. These results were used to explain the resistivity measurements carried out on dense ceramics prepared from our powders sintered at low temperature (700–750 °C) in a Spark Plasma Sintering apparatus

    Sur la formation des prix dans l'économie du haut Moyen Âge

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    International audienceDuring the Early Middle Ages, market exchange coexists alongside non market exchange. The aim of this paper is to examine how possibly this two great modalities of exchange can be present at the same time in the economic life, in a period in which the existence of marketable surplus is a problem. The presumed deficiencies of the means of production, their presumed unsuitability with the economic development, the postulated incompetence of the élites, make the market exchange, and even the possibility that a profit sector exists in the economy, undervalued, or even denied. The social élites, just as the small scale actors, whatever their activity could be, farming or trading, have beside production, consumption and exchange, very subtle and complex attitudes. We shall see that some cognitive capacities exist within the groups of economic actors, that go far beyond an empirical knowledge and result from a reflection about the finalities of economics, the functions of wealth and about its use in a Christian society. Sixth century monks know how the prices are formed, as they know that there is a difference between price formation and price fixation, and also know how to manage with rules to ensure one's salvation. This knowledge also exists, within a very different framework, and the comparison between the practice of such men as Adalhard of Corbie and saint Benedict's Rule (or with the Master's Rule), give an explanation of their attitude toward prices: for them, things have a value and it is possible to measure it as well as modify it. The attitude of the Carolingian and post-carolingian élites during the famines allows us to understand how social and political authorities understood market exchange rules within a Christian society. At the end, there is a shared but tacit, as well, knowledge about the functioning of exchanges and a clear awareness about the fact that they can take several forms depending on the result aimed at.Durant le haut Moyen Âge, l'échange marchand coexiste avec l'échange non-marchand. Le but de cet article est d'examiner les conditions de possibilité de la présence de ces deux grandes modalités de l'échange au sein de la vie économique durant une période où l'existence même de surplus commerciaux fait question. Les déficiences supposées des moyens de production, leur éventuelle inadéquation avec le développement, l'incompétence elle aussi postulée des élites font que l'échange par le marché et la possibilité qu'il existe un secteur de profit sont le plus souvent sous-évalués voire niés. Les élites sociales tout comme les acteurs de petit niveau, qu'il s'agisse d'agriculteurs ou de commerçants, ont à l'égard de la production, de la consommation et de l'échange des attitudes très nuancées et complexes. On montre qu'il existe des capacités cognitives qui vont au-delà d'un savoir faire empirique mais relèvent d'une réflexion sur les finalités mêmes de la vie économique, sur les fonctions de la richesse et sur leur usage dans un monde chrétien. Les moines savent, au VIe siècle, comment se forment les prix et comprennent la différence entre formation et fixation des prix. Il savent aussi comment il faut jouer avec ces règles pour assurer son salut. Ce savoir existe aussi au IXe siècle, dans un monde très différent, et la comparaison entre les pratiques d'hommes comme Adalhard de Corbie et la règle de saint Benoît (ou celle du Maître) livre l'explication de leur attitude à l'égard des prix : pour eux les choses ont une valeur qu'il est possible de mesurer et de modifier. L'attitude des élites carolingiennes et post-carolingiennes lors des famines permet d'établir comment les autorités ont compris les règles de l'échange marchand à l'intérieur d'un monde chrétien. Il y a au bout du compte un savoir partagé mais tacite sur le fonctionnement des échanges et une conscience de ce que, en fonction des buts poursuivis, ceux-ci peuvent prendre plusieurs formes

    Evaluating the use of ABBA-BABA statistics to locate introgressed loci

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    Several methods have been proposed to test for introgression across genomes. One method tests for a genome-wide excess of shared derived alleles between taxa using Patterson’s D statistic, but does not establish which loci show such an excess or whether the excess is due to introgression or ancestral population structure. Several recent studies have extended the use of D by applying the statistic to small genomic regions, rather than genome-wide. Here, we use simulations and whole-genome data from Heliconius butterflies to investigate the behavior of D in small genomic regions. We find that D is unreliable in this situation as it gives inflated values when effective population size is low, causing D outliers to cluster in genomic regions of reduced diversity. As an alternative, we propose a related statistic f ̂ d, a modified version of a statistic originally developed to estimate the genome-wide fraction of admixture. f ̂ d is not subject to the same biases as D, and is better at identifying introgressed loci. Finally, we show that both D and f ̂ d outliers tend to cluster in regions of low absolute divergence (dXY), which can confound a recently proposed test for differentiating introgression from shared ancestral variation at individual loci

    Shear-induced pressure changes and seepage phenomena in a deforming porous layer-I

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    We present a model for flow and seepage in a deforming, shear-dilatant sensitive porous layer that enables estimates of the excess pore fluid pressures and flow rates in both the melt and solid phase to be captured simultaneously as a function of stress rate. Calculations are relevant to crystallizing magma in the solidosity range 0.5–0.8 (50–20 per cent melt), corresponding to a dense region within the solidification front of a crystallizing magma chamber. Composition is expressed only through the viscosity of the fluid phase, making the model generally applicable to a wide range of magma types. A natural scaling emerges that allows results to be presented in non-dimensional form. We show that all length-scales can be expressed as fractions of the layer height H, timescales as fractions of H2(nβ'θ+ 1)/(θk) and pressures as fractions of . Taking as an example the permeability k in the mush of the order of magnitude 1015 m2 Pa1 s1, a layer thickness of tens of metres and a mush strength (θ) in the range 108–1012 Pa, an estimate of the consolidation time for near-incompressible fluids is of the order of 105–109 s. Using mush permeability as a proxy, we show that the greatest maximum excess pore pressures develop consistently in rhyolitic (high-viscosity) magmas at high rates of shear ( , implying that during deformation, the mechanical behaviour of basaltic and rhyolitic magmas will differ. Transport parameters of the granular framework including tortuosity and the ratio of grain size to layer thickness (a/H) will also exert a strong effect on the mechanical behaviour of the layer at a given rate of strain. For dilatant materials under shear, flow of melt into the granular layer is implied. Reduction in excess pore pressure sucks melt into the solidification front at a velocity proportional to the strain rate. For tectonic rates (generally 1014 s1), melt upwelling (or downwelling, if the layer is on the floor of the chamber) is of the order of cm yr1. At higher rates of loading comparable with emplacement of some magmatic intrusions (1010 s1), melt velocities may exceed effects due to instabilities resulting from local changes in density and composition. Such a flow carries particulates with it, and we speculate that these may become trapped in the granular layer depending on their sizes. If on further solidification the segregated grain size distribution of the particulates is frozen in the granular layer, structure formation including layering and grading may result. Finally, as the process settles down to a steady state, the pressure does not continue to decrease. We find no evidence for critical rheological thresholds, and the process is stable until so much shear has been applied that the granular medium fails, but there is no hydraulic failure

    Fungicides and the grapevine wood mycobiome: a case study on Tracheomycotic Ascomycete Phaemoniella chlamydospora reveals potential for two novel control strategies

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    Original ResearchPhaeomoniella chlamydospora is a tracheomycotic fungus that colonizes the xylem of grapevines (Vitis vinifera L.), causing wood discoloration, brown wood streaking, gummosis, and wood necrosis, which negatively affect the overall health, productivity, and life span of vines. Current control strategies to prevent or cope with P. chlamydospora infections are frequently ineffective. Moreover, it is unclear how fungicides commonly applied in vineyards against downy and powdery mildew agents affect the wood mycobiome, including wood pathogens such as P. chlamydospora. In this study, we used next-generation sequencing to assess the effects of foliar spray of grapevines with inorganic (copper oxychloride and sulfur), synthetic (penconazole and fosetyl-aluminum), and natural (Blad) fungicides currently used against the downy and powdery mildews. The subjects of our investigation were (i) the resident wood mycobiome, (ii) the early colonization by a consortium of fungal wood endophytes (ACEA1), (iii) the wood colonization success of P. chlamydospora, and (iv) the in planta interaction between P. chlamydospora and ACEA1, under greenhouse conditions, in rooted grapevine cuttings of cv. Cabernet Sauvignon. The data obtained suggest that the resident mycobiome is affected by different fungicide treatments. In addition, the early colonization success of the endophytes composing ACEA1 varied in response to fungicides, with relative abundances of some taxa being overrepresented or underrepresented when compared with the control. The wood colonization by P. chlamydospora comported significant changes in the mycobiome composition, and in addition, it was greatly affected by the foliar spray with Blad, which decreased the relative abundance of this pathogen 12-fold (4.9%) when compared with the control (60.7%) and other treatments. The presence of the pathogen also decreased considerably when co-inoculated into the plant with ACEA1, reaching relative abundances between 13.9% and 2.0%, depending on the fungicide treatment applied. This study shows that fungicides sprayed to prevent infections of powdery and downy mildews have an control strategies to fight P. chlamydospora, namely, the foliar spray with Blad and the use of ACEA1. Further studies to confirm these results are requiredinfo:eu-repo/semantics/publishedVersio
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